-
1
-
-
40949095655
-
Guide to Receptors and Channels (GRAC), 3rd edition
-
Suppl. 2
-
Alexander SP, Mathie A, Peters JA (2008). Guide to Receptors and Channels (GRAC), 3rd edition. Br J Pharmacol 153 (Suppl. 2 S1 S209.
-
(2008)
Br J Pharmacol
, vol.153
-
-
Alexander, S.P.1
Mathie, A.2
Peters, J.A.3
-
2
-
-
31044432330
-
Mechanism of action of a novel human ether-a-go-go-related gene channel activator
-
Casis O, Olesen SP, Sanguinetti MC (2006). Mechanism of action of a novel human ether-a-go-go-related gene channel activator. Mol Pharmacol 69 : 658 665.
-
(2006)
Mol Pharmacol
, vol.69
, pp. 658-665
-
-
Casis, O.1
Olesen, S.P.2
Sanguinetti, M.C.3
-
4
-
-
45849107163
-
Antiarrhythmic properties of a rapid delayed-rectifier current activator in rabbit models of acquired long QT syndrome
-
Diness TG, Yeh YH, Qi XY, Chartier D, Tsuji Y, Hansen RS et al. (2008). Antiarrhythmic properties of a rapid delayed-rectifier current activator in rabbit models of acquired long QT syndrome. Cardiovasc Res 79 : 61 69.
-
(2008)
Cardiovasc Res
, vol.79
, pp. 61-69
-
-
Diness, T.G.1
Yeh, Y.H.2
Qi, X.Y.3
Chartier, D.4
Tsuji, Y.5
Hansen, R.S.6
-
5
-
-
0037910175
-
Expression and function of KCNH2 (HERG) in the human jejunum
-
Farrelly AM, Ro S, Callaghan BP, Khoyi MA, Fleming N, Horowitz B et al. (2003). Expression and function of KCNH2 (HERG) in the human jejunum. Am J Physiol Gastrointest Liver Physiol 284 : G883 G895.
-
(2003)
Am J Physiol Gastrointest Liver Physiol
, vol.284
-
-
Farrelly, A.M.1
Ro, S.2
Callaghan, B.P.3
Khoyi, M.A.4
Fleming, N.5
Horowitz, B.6
-
6
-
-
24344487347
-
Expression pattern of the ether-a-go-go-related (ERG) family proteins in the adult mouse central nervous system: Evidence for coassembly of different subunits
-
Guasti L, Cilia E, Crociani O, Hofmann G, Polvani S, Becchetti A et al. (2005). Expression pattern of the ether-a-go-go-related (ERG) family proteins in the adult mouse central nervous system: evidence for coassembly of different subunits. J Comp Neurol 491 : 157 174.
-
(2005)
J Comp Neurol
, vol.491
, pp. 157-174
-
-
Guasti, L.1
Cilia, E.2
Crociani, O.3
Hofmann, G.4
Polvani, S.5
Becchetti, A.6
-
8
-
-
30044441212
-
Activation of human ether-a-go-go-related gene potassium channels by the diphenylurea 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643)
-
Hansen RS, Diness TG, Christ T, Demnitz J, Ravens U, Olesen SP et al. (2006a). Activation of human ether-a-go-go-related gene potassium channels by the diphenylurea 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643). Mol Pharmacol 69 : 266 277.
-
(2006)
Mol Pharmacol
, vol.69
, pp. 266-277
-
-
Hansen, R.S.1
Diness, T.G.2
Christ, T.3
Demnitz, J.4
Ravens, U.5
Olesen, S.P.6
-
9
-
-
33748936880
-
Biophysical characterization of the new human ether-a-go-go-related gene channel opener NS3623 [n-(4-bromo-2-(1H-tetrazol-5-yl)-phenyl)-N′- (3′-trifluoromethylphenyl)urea]
-
Hansen RS, Diness TG, Christ T, Wettwer E, Ravens U, Olesen SP et al. (2006b). Biophysical characterization of the new human ether-a-go-go-related gene channel opener NS3623 [N-(4-bromo-2-(1H-tetrazol-5-yl)-phenyl)-N′- (3′-trifluoromethylphenyl)urea]. Mol Pharmacol 70 : 1319 1329.
-
(2006)
Mol Pharmacol
, vol.70
, pp. 1319-1329
-
-
Hansen, R.S.1
Diness, T.G.2
Christ, T.3
Wettwer, E.4
Ravens, U.5
Olesen, S.P.6
-
10
-
-
34248586985
-
Pharmacological activation of rapid delayed rectifier potassium current suppresses bradycardia-induced triggered activity in the isolated guinea pig heart
-
Hansen RS, Olesen SP, Grunnet M (2007). Pharmacological activation of rapid delayed rectifier potassium current suppresses bradycardia-induced triggered activity in the isolated guinea pig heart. J Pharmacol Exp Ther 321 : 996 1002.
-
(2007)
J Pharmacol Exp Ther
, vol.321
, pp. 996-1002
-
-
Hansen, R.S.1
Olesen, S.P.2
Grunnet, M.3
-
11
-
-
66749174141
-
A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophrenia
-
Huffaker SJ, Chen J, Nicodemus KK, Sambataro F, Yang F, Mattay V et al. (2009). A primate-specific, brain isoform of KCNH2 affects cortical physiology, cognition, neuronal repolarization and risk of schizophrenia. Nat Med 15 : 509 518.
-
(2009)
Nat Med
, vol.15
, pp. 509-518
-
-
Huffaker, S.J.1
Chen, J.2
Nicodemus, K.K.3
Sambataro, F.4
Yang, F.5
Mattay, V.6
-
12
-
-
0036186510
-
Dual-function vector for protein expression in both mammalian cells and Xenopus laevis oocytes
-
Jespersen T, Grunnet M, Angelo K, Klaerke DA, Olesen SP (2002). Dual-function vector for protein expression in both mammalian cells and Xenopus laevis oocytes. Biotechniques 32 : 536 540.
-
(2002)
Biotechniques
, vol.32
, pp. 536-540
-
-
Jespersen, T.1
Grunnet, M.2
Angelo, K.3
Klaerke, D.A.4
Olesen, S.P.5
-
13
-
-
7244226352
-
Cardiac IKr channels minimally comprise hERG 1a and 1b subunits
-
Jones EM, Roti Roti EC, Wang J, Delfosse SA, Robertson GA (2004). Cardiac IKr channels minimally comprise hERG 1a and 1b subunits. J Biol Chem 279 : 44690 44694.
-
(2004)
J Biol Chem
, vol.279
, pp. 44690-44694
-
-
Jones, E.M.1
Roti Roti, E.C.2
Wang, J.3
Delfosse, S.A.4
Robertson, G.A.5
-
15
-
-
0032538558
-
+ channel splice variant common in human heart lacks a C-terminal domain required for expression of rapidly activating delayed rectifier current
-
+ channel splice variant common in human heart lacks a C-terminal domain required for expression of rapidly activating delayed rectifier current. J Biol Chem 273 : 27231 27235.
-
(1998)
J Biol Chem
, vol.273
, pp. 27231-27235
-
-
Kupershmidt, S.1
Snyders, D.J.2
Raes, A.3
Roden, D.M.4
-
16
-
-
77749322248
-
Differential expression of hERG1 channel isoforms reproduces properties of native I(Kr) and modulates cardiac action potential characteristics
-
Larsen AP, Olesen SP (2010). Differential expression of hERG1 channel isoforms reproduces properties of native I(Kr) and modulates cardiac action potential characteristics. PLoS ONE 5 : e9021.
-
(2010)
PLoS ONE
, vol.5
, pp. 9021
-
-
Larsen, A.P.1
Olesen, S.P.2
-
17
-
-
50049112701
-
Characterization of hERG1a and hERG1b potassium channels - A possible role for hERG1b in the I (Kr) current
-
Larsen AP, Olesen SP, Grunnet M, Jespersen T (2008). Characterization of hERG1a and hERG1b potassium channels-a possible role for hERG1b in the I (Kr) current. Pflugers Arch 456 : 1137 1148.
-
(2008)
Pflugers Arch
, vol.456
, pp. 1137-1148
-
-
Larsen, A.P.1
Olesen, S.P.2
Grunnet, M.3
Jespersen, T.4
-
20
-
-
0036720936
-
Functional and molecular identification of ERG channels in murine portal vein myocytes
-
Ohya S, Horowitz B, Greenwood IA (2002). Functional and molecular identification of ERG channels in murine portal vein myocytes. Am J Physiol Cell Physiol 283 : C866 C877.
-
(2002)
Am J Physiol Cell Physiol
, vol.283
-
-
Ohya, S.1
Horowitz, B.2
Greenwood, I.A.3
-
21
-
-
35348824829
-
Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator
-
Perry M, Sachse FB, Sanguinetti MC (2007). Structural basis of action for a human ether-a-go-go-related gene 1 potassium channel activator. Proc Natl Acad Sci USA 104 : 13827 13832.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 13827-13832
-
-
Perry, M.1
Sachse, F.B.2
Sanguinetti, M.C.3
-
23
-
-
0029002969
-
A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel
-
Sanguinetti MC, Jiang C, Curran ME, Keating MT (1995). A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel. Cell 81 : 299 307.
-
(1995)
Cell
, vol.81
, pp. 299-307
-
-
Sanguinetti, M.C.1
Jiang, C.2
Curran, M.E.3
Keating, M.T.4
-
24
-
-
0029007356
-
HERG, a human inward rectifier in the voltage-gated potassium channel family
-
Trudeau MC, Warmke JW, Ganetzky B, Robertson GA (1995). HERG, a human inward rectifier in the voltage-gated potassium channel family. Science 269 : 92 95.
-
(1995)
Science
, vol.269
, pp. 92-95
-
-
Trudeau, M.C.1
Warmke, J.W.2
Ganetzky, B.3
Robertson, G.A.4
-
25
-
-
0028292927
-
A family of potassium channel genes related to eag in Drosophila and mammals
-
Warmke JW, Ganetzky B (1994). A family of potassium channel genes related to eag in Drosophila and mammals. Proc Natl Acad Sci USA 91 : 3438 3442.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 3438-3442
-
-
Warmke, J.W.1
Ganetzky, B.2
-
26
-
-
44249098289
-
Probing the binding sites and mechanisms of action of two human ether-a-go-go-related gene channel activators, 1,3-bis-(2-hydroxy-5- trifluoromethyl-phenyl)-urea (NS1643) and 2-[2-(3,4-dichloro-phenyl)-2,3- dihydro-1H-isoindol-5-ylamino]-nicotinic acid (PD307243)
-
Xu X, Recanatini M, Roberti M, Tseng GN (2008). Probing the binding sites and mechanisms of action of two human ether-a-go-go-related gene channel activators, 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643) and 2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1H-isoindol-5-ylamino]-nicotinic acid (PD307243). Mol Pharmacol 73 : 1709 1721.
-
(2008)
Mol Pharmacol
, vol.73
, pp. 1709-1721
-
-
Xu, X.1
Recanatini, M.2
Roberti, M.3
Tseng, G.N.4
-
27
-
-
23944441185
-
Novel potent human ether-a-go-go-related gene (hERG) potassium channel enhancers and their in vitro antiarrhythmic activity
-
Zhou J, Augelli-Szafran CE, Bradley JA, Chen X, Koci BJ, Volberg WA et al. (2005). Novel potent human ether-a-go-go-related gene (hERG) potassium channel enhancers and their in vitro antiarrhythmic activity. Mol Pharmacol 68 : 876 884.
-
(2005)
Mol Pharmacol
, vol.68
, pp. 876-884
-
-
Zhou, J.1
Augelli-Szafran, C.E.2
Bradley, J.A.3
Chen, X.4
Koci, B.J.5
Volberg, W.A.6
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