Pharmacological activation of rapid delayed rectifier potassium current suppresses bradycardia-induced triggered activity in the isolated guinea pig heart

Journal of Pharmacology and Experimental Therapeutics

Volumn 321, Issue 3, 2007, Pages 996-1002

  Hansen, Rie Schultz ^a,b   Olesen, Søren Peter ^b   Grunnet, Morten ^a,b  

^a NEUROSEARCH A S   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

DELAYED RECTIFIER POTASSIUM CHANNEL; N (4 BROMO 2 (1H TETRAZOL 5 YL) PHENYL) N' (3' TRIFLUOROMETHYLPHENYL) UREA; NS 3623; POTASSIUM CHANNEL HERG; UNCLASSIFIED DRUG; UREA DERIVATIVE;

ANIMAL TISSUE; ARTICLE; BRADYCARDIA; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; GUINEA PIG; HEART; HEART MUSCLE POTENTIAL; ISOLATED HEART; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; QT INTERVAL;

ACTION POTENTIALS; ANIMALS; ANTI-ARRHYTHMIA AGENTS; BRADYCARDIA; ELECTROCARDIOGRAPHY; ETHER-A-GO-GO POTASSIUM CHANNELS; GUINEA PIGS; HEART; HEART RATE; PERFUSION; PHENYLUREA COMPOUNDS; PIPERIDINES; PYRIDINES; TETRAZOLES; VENTRICULAR FUNCTION;

EID: 34248586985     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.106.118448     Document Type: Article

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