What can we learn about breast cancer from stem cells?

Advances in Experimental Medicine and Biology

Volumn 617, Issue , 2008, Pages 17-22

  Clarke, Michael F ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CANCER; CANCER STEM CELL; CELL DIFFERENTIATION; CELL DIVISION; CELL ISOLATION; CELL MATURATION; CONFERENCE PAPER; HUMAN; NONHUMAN; PRIORITY JOURNAL; TUMOR GROWTH; BREAST TUMOR; FEMALE; PATHOLOGY; REVIEW;

BREAST NEOPLASMS; FEMALE; HUMANS; NEOPLASTIC STEM CELLS;

EID: 46749096396     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-0-387-69080-3_2     Document Type: Conference Paper

References (49)

1. Clarke MF, Fuller M (2006) Stem cells and cancer: two faces of eve. Cell 124:1111-5.
2. Fearon ER, Vogelstein B (1990) A genetic model for colorectal tumorigenesis. Cell 61:759-767.
3. Smith GH, Chepko G (2001) Mammary epithelial stem cells. Microsc Res Tech 52:190-203.
4. Blanpain C, Lowry WE, Geoghegan A, et al. (2004) Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche. Cell 118:635-48.
5. Nilsson E, Parrott JA, Skinner MK (2001) Basic fibroblast growth factor induces primordial follicle development and initiates folliculogenesis. Mol Cell Endocrinol 175:123-30.
6. Vasioukhin V, Bauer C, Degenstein L, et al. (2001) Hyperproliferation and defects in epithelial polarity upon conditional ablation of alpha-catenin in skin. Cell 104:605-17.
7. Spangrude GJ, Heimfeld S, Weissman IL (1988) Purification and characterization of mouse hematopoietic stem cells. Science 241:58-62.
8. Blyszczuk P (2004) Embryonic stem cells differentiate into insulin-producing cells without selection of nestin-expressing cells. Int J Dev Biol 48:1095-104.
9. Bouwens L, De Blay E (1996) Islet morphogenesis and stem cell markers in rat pancreas. J Histochem Cytochem 44:947-51.
10. Doetsch F, Petreanu L, Caille I, et al. (2002) EGF converts transit-amplifying neurogenic precursors in the adult brain into multipotent stem cells. Neuron 36:1021-34.
11. Chepko G, Smith GH (1999) Mammary epithelial stem cells: our current understanding. J Mammary Gland Biol Neoplasia 4:35-52.
12. Easterday MC (2003) Neural progenitor genes. Germinal zone expression and analysis of genetic overlap in stem cell populations. Dev Biol 264:309-22.
13. Taipale J, Beachy PA (2001) The Hedgehog and Wnt signalling pathways in cancer. Nature 411:349-54.
14. van Es JH (2005) Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells. Nature 435:959-63.
15. Chan EF, Gat U, McNiff JM, Fuchs EA (1999) Common human skin tumour is caused by activating mutations in beta-catenin. Nat Genet 21:410-3.
16. Shackleton M (2006) Generation of a functional mammary gland from a single stem cell. Nature 439:84-8.
17. Morrison SJ, et al. (2002) A genetic determinant that specifically regulates the frequency of hematopoietic stem cells. J Immunol 168:635-42.
18. Allman D, Aster JC, Pear WS (2002) Notch signaling in hematopoiesis and early lymphocyte development. Immunol Rev 187:75-86.
19. Beachy PA, Karhadkar SS, Berman DM (2004) Tissue repair and stem cell renewal in carcinogenesis. Nature 432:324-31.
20. Boyer LA, et al. (2005) Core transcriptional regulatory circuitry in human embryonic stem cells. Cell 122:947-56.
21. Cavaleri F, Scholer HR (2003) Nanog: a new recruit to the embryonic stem cell orchestra. Cell 113:551-2.
22. Ema H, Takano H, Sudo K, Nakauchi H (2000) In vitro self-renewal division of hematopoietic stem cells. J Exp Med 192:1281-8.
23. He XC, et al. (2004) BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling. Nat Genet 36:1117-21.
24. Hitoshi S, et al. (2002) Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells. Genes Dev 16:846-58.
25. Huntly BJ, et al. (2004) MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors. Cancer Cell 6:587-96.
26. Kyba M, Perlingeiro RC, Daley GQ (2002) HoxB4 confers definitive lymphoid-myeloid engraftment potential on embryonic stem cell and yolk sac hematopoietic progenitors. Cell 109, 29-37.
27. Loh YH, et al. (2006) The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat Genet 38:431-40.
28. Mitsui K, et al. (2003) The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 113:631-42.
29. Molofsky AV, et al. (2003) Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation. Nature 425:962-7.
30. Morrison SJ, et al. (2000) Transient notch activation initiates an irreversible switch from neurogenesis to gliogenesis by neural crest stem cells. Cell 101:499-510.
31. Nakamura Y, et al. (2000) The bHLH gene hes1 as a repressor of the neuronal commitment of CNS stem cells. J Neurosci 20:283-93.
32. Ohta H, et al. (2002) Polycomb group gene rae28 is required for sustaining activity of hematopoietic stem cells. J Exp Med 195:759-70.
33. Park IK, et al. (2003) Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells. Nature 423:302-5.
34. Reya T, et al. (2003) A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature 423:409-14.
35. Xu RH, et al. (2005) Basic FGF and suppression of BMP signaling sustain undifferentiated proliferation of human ES cells. Nat Meth 2:185-90.
36. Ying QL, Nichols J, Chambers I, Smith A (2003) BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell 115:281-92.
37. Zaehres H, et al. (2005) High-efficiency RNA interference in human embryonic stem cells. Stem Cells 23:299-305.
38. Liang SH, Clarke MF (2001) Regulation of p53 localization. Eur J Biochem 268:2779-83.
39. Krishnamurthy J, et al. (2006) p16INK4a induces an age-dependent decline in islet regenerative potential. Nature 443:453-7.
40. Molofsky AV, et al. (2006) Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing. Nature 443:448-52.
41. Janzen V, et al. (2006) Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a. Nature 443:421-6.
42. Lee TI, et al. (2006) Control of developmental regulators by Polycomb in human embryonic stem cells. Cell 125:301-13.
43. Akala OO, Clarke MF (2006) Hematopoietic stem cell self-renewal. Curr Opin Genet Dev 16:496-501.
44. Reya T, Morrison SJ, Clarke MF, Weissman IL (2001) Stem cells, cancer, and cancer stem cells. Nature 414:105-11.
45. Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF (2003) Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci USA 100:3983-8.
46. Clarke MF (2004) Neurobiology: at the root of brain cancer. Nature 432:281-2.
47. Fang D, et al. (2005) A tumorigenic subpopulation with stem cell properties in melanomas. Cancer Res 65:9328-37.
48. Singh SK, et al. (2003) Identification of a cancer stem cell in human brain tumors. Cancer Res 63:5821-8.
49. Liu R, et al. (2007) The prognastic role of a gene signature from tumorigenic breast-cancers cells. N Engl J Med 356:217-26.