Endothelial cells promote neural stem cell proliferation and differentiation associated with VEGF activated Notch and Pten signaling

Developmental Dynamics

Volumn 239, Issue 9, 2010, Pages 2345-2353

  Sun, Jinqiao ^a,b   Zhou, Wenhao ^a,b   Ma, Duan ^c,d   Yang, Yi ^a,b  

^a CHILDREN S HOSPITAL OF FUDAN UNIVERSITY   (China)

^b BEIJING HOSPITAL   (China)

^c BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^d FUDAN UNIVERSITY   (China)

Author keywords

Endothelial cell; Neural stem cell; Neurogenesis; Notch; Pten

Indexed keywords

NOTCH RECEPTOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; SMALL INTERFERING RNA; VASCULOTROPIN;

ANGIOGENESIS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL COUNT; CELL DIFFERENTIATION; CELL PROLIFERATION; COCULTURE; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE EXPRESSION; GENE FUNCTION; GLIA CELL; MOUSE; NEURAL STEM CELL; NEWBORN; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT; RNA INTERFERENCE; SCREENING;

ANIMALS; BIOLOGICAL MARKERS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; COCULTURE TECHNIQUES; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MICE; MOLECULAR SEQUENCE DATA; NEOVASCULARIZATION, PHYSIOLOGIC; NEURAL STEM CELLS; NEUROGENESIS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PTEN PHOSPHOHYDROLASE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NOTCH; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

RATTUS;

EID: 77956278486     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.22377     Document Type: Article

References (40)

1. Alexson TO, Hitoshi S, Coles BL, Bernstein A, van der Kooy D. 2006. Notch signaling is required to maintain all neural stem cell populations - irrespective of spatial or temporal niche. Dev Neurosci 28:34-48.
2. Backman SA, Stambolic V, Suzuki A, Haight J, Elia A, Pretorius J, Tsao MS, Shannon P, Bolon B, Ivy GO, Mak TW. 2001. Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease. Nat Genet 29:396-403.
3. Basak O, Taylor V. 2009. Stem cells of the adult mammalian brain and their niche. Cell Mol Life Sci 66:1057-1072.
4. Capela A, Temple S. 2002. LeX/ssea-1 is expressed by adult mouse CNS stem cells identifying them as nonependymal. Neuron 35:865-875.
5. Carlson ME, Conboy IM. 2007. Regulating the Notch pathway in embryonic, adult and old stem cells. Curr Opin Pharmacol 7:303-309.
6. Corbin JG, Gaiano N, Juliano SL, Poluch S, Stancik E, Haydar TF. 2008. Regulation of neural progenitor cell development in the nervous system. J Neurochem 106:2272-2287.
7. Frantseva MV, Carlen PL, Beheiry H. 1999. A submersion method to induce hypoxic damage in organotypic hippocampal cultures. J Neurosci. Methods 89:25-31.
8. Fuches E, Tumbar T, Guasch G. 2004. Socializing with the neighbors: stem cells and their niche. Cell 116:769-778.
9. Giuliani N, Morandi F, Tagliaferri S, Lazzaretti M, Donofrio G, Bonomini S, Sala R, Mangoni M, Rizzoli V. 2007. Production of Wnt inhibitors by myeloma cells: potential effects on canonical Wnt pathway in the bone microenvironment. Cancer Res 67:7665-7674.
10. Gregorian C, Nakashima J, Le Belle J, Ohab J, Kim R, Liu A, Smith KB, Groszer M, Garcia AD, Sofroniew MV, Carmichael ST, Kornblum HI, Liu X, Wu H. 2009. Pten deletion in adult neural stem/progenitor cells enhances constitutive neurogenesis. J Neurosci 29:1874-1886.
11. Groszer M, Erickson R, Scripture-Adams DD, Lesche R, Trumpp A, Zack JA, Kornblum HI, Liu X, Wu H. 2001. Negative regulation of neural stem/progenitor cell proliferation by the Pten tumor suppressor gene in vivo. Science 294:2186-2189.
12. Jiao J, Chen DF. 2008. Induction of neurogenesis in nonconventional neurogenic regions of the adult central nervous system by niche astrocyte-produced signals. Stem Cells 26:1221-1230.
13. Jin K, Zhu Y, Sun Y, Mao XO, Xie L, Greenberg DA. 2002. Vascular endothelial growth factor (VEGF) stimulates neurogenesis in vitro and in vivo. Proc Natl Acad Sci USA 99:11946-11950.
14. Jin-qiao S, Bin S, Wen-hao Z, Yi Y. 2009. Basic fibroblast growth factor stimulates the proliferation and differentiation of neural stem cells in neonatal rats after ischemic brain injury. Brain Dev 31:331-340.
15. Kwon CH, Zhu X, Zhang J, Knoop LL, Tharp R, Smeyne RJ, Eberhart CG, Burger PC, Baker SJ. 2001. Pten regulates neuronal soma size: a mouse model of Lhermitte-Duclos disease. Nat Genet 29:404-411.
16. Leventhal C, Rafii S, Rafii D, Shahar A, Goldman SA. 1999. Endothelial trophic support of neuronal production and recruitment from the adult mammalian subependyma. Mol Cell Neurosci 13:450-464.
17. Louissaint A Jr, Rao S, Leventhal C, Goldman SA. 2002. Coordinated interaction of neurogenesis and angiogenesis in the adult songbird brain. Neuron 34:945-960.
18. Mabie PC, Mehler MF, Kessler JA. 1999. Multiple roles of bone morphogenetic protein signaling in the regulation of cortical cell number and phenotype. J Neurosci 19:7077-7088.
19. Mercier F, Kitasako JT, Hatton GI. 2002. Anatomy of the brain neurogenic zones revisited: fractones and the fibroblast/macrophage network. J Comp Neurol 451:170-188.
20. Moyse E, Segura S, Liard O, Mahaut S, Mechawar N. 2008. Microenvironmental determinants of adult neural stem cell proliferation and lineage commitment in the healthy and injured central nervous system. Curr Stem Cell Res Ther 3:163-184.
21. Palmer TD, Willhoite AR, Gage FH. 2000. Vascular niche for adult hippocampal neurogenesis. J Comp Neurol 425:479-494.
22. Parent JM, Vexler ZS, Gong C, Derugin N, Ferriero DM. 2002. Rat forebrain neurogenesis and striatal neuron replacement after focal stroke. Ann Neurol 52:802-813.
23. Perez Velazquez JL, Frantseva MV, Carlen PL. 1997. In vitro ischemia promotes glutamate-mediated free radical generation and intracellular calcium accumulation in pyramidal neurons of cultured hippocampal slices J Neurosci 23:9085-9094.
24. Salama-Cohen P, Arevalo MA, Meier J, Grantyn R, Rodríguez- Tébar A. 2005. NGF controls dendrite development in hippocampal neurons by binding to p75 NTR and modulating the cellular targets of Notch. Mol Biol Cell 16:339-347.
25. Salama-Cohen P, Arevalo MA, Grantyn R, Rodríguez-Tébar A. 2006. Notch and NGF/p75NTR control dendrite morphology and the balance of excitatory/inhibitory synaptic input to hippocampal neurones through Neurogenin 3. J Neurochem 97:1269-1278.
26. Shen Q, Goderie SK, Jin L, Karanth N, Sun Y, Abramova N, Vincent P, Pumiglia K, Temple S. 2004. endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cells. Science 304:1338-1340.
27. Sumioka T, Ikeda K, Okada Y, Yamanaka O, Kitano A, Saika S. 2008. Inhibitory effect of blocking TGF-beta/Smad signal on injury-induced fibrosis of corneal endothelium. Mol Vis 14:2272-2281.
28. Tusher V, Tibshirani R, Chu G. 2001. Significance analysis of microarrays applied to transcriptional responses to ionizing radiation. Proc Natl Acad Sci USA 98:5116-5121.
29. Vemuganti R, Dempsey RJ, Bowen KK. 2004. Inhibition of intercellular adhesion molecule-1 protein expression by antisense oligonucleotides is neuroprotective after transient middle cerebral artery occlusion in rat. Stroke 35:179-184.
30. Wang Y, Jin K, Mao XO, Xie L, Banwait S, Marti HH, Greenberg DA. 2007. VEGF-overexpressing transgenic mice show enhanced post-ischemic neurogenesis and neuromigration. J Neurosci Res 85:740-747.
31. West MJ, Slomianka L, Gundersen HJ. 1991. Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator. Anat Rec 231:482-497.
32. Wurmser AE, Palmer TD, Gage FH. 2004. Cellular interactions in the stem cell niche. Science 304:1253-1255.
33. Xiao Z, Kong Y, Yang S, Li M, Wen J, Li L. 2007. Upregulation of Flk-1 by bFGF via the ERK pathway is essential for VEGF-mediated promotion of neural stem cell proliferation. Cell Res 17:73-79.
34. Xie K, Wei D, Shi Q, Huang S. 2004. Constitutive and inducible expression and regulation of vascular endothelial growth factor. Cytokine Growth Factor Rev 15:297-324. (Pubitemid 39140697)
35. Yoon K, Gaiano N. 2005. Notch signaling in the mammalian central nervous system: insights from mouse mutants. Nat Neurosci 8:709-715.
36. Zang S, Guo R, Zhang L, Lu Y. 2007. Integration of statistical inference methods and a novel control measure to improve sensitivity and specificity of data analysis in expression profiling studies. J Biomed Inform 40:552-560.
37. Zhang S. 2007. A comprehensive evaluation of SAM, the SAM R-package and a simple modification to improve its performance. BMC Bioinformatics 8:230.
38. Zhang H, Vutskits L, Pepper MS, Kiss JZ. 2003. VEGF is a chemoattractant for FGF-2 stimulated neural progenitors. J Cell Biol 163:1375-1384.
39. Zheng H, Ying H, Yan H, Kimmelman AC, Hiller DJ, Chen AJ, Perry SR, Tonon G, Chu GC, Ding Z, Stommel JM, Dunn KL, Wiedemeyer R, You MJ, Brennan C, Wang YA, Ligon KL, Wong WH, Chin L, DePinho RA. 2008. p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation. Nature 455:1129-1133.
40. Zhu W, Fan Y, Frenzel T, Gasmi M, Bartus RT, Young WL, Yang GY, Chen Y. 2008. Insulin growth factor-1 gene transfer enhances neurovascular remodeling and improves long-term stroke outcome in mice. Stroke 39:1254-1261.