-
1
-
-
0027429040
-
Expression of collagen I, smooth muscle alpha-actin, and vimentin during the healing of alkali-burned and lacerated corneas
-
Ishizaki M, Zhu G, Haseba T, Shafer SS, Kao WW. Expression of collagen I, smooth muscle alpha-actin, and vimentin during the healing of alkali-burned and lacerated corneas. Invest Ophthalmol Vis Sci 1993; 34:3320-8.
-
(1993)
Invest Ophthalmol Vis Sci
, vol.34
, pp. 3320-3328
-
-
Ishizaki, M.1
Zhu, G.2
Haseba, T.3
Shafer, S.S.4
Kao, W.W.5
-
2
-
-
0027169448
-
Epithelial basement membrane in alkali-burned corneas in rats. Immunohistochemical study
-
Saika S, Kobata S, Hashizume N, Okada Y, Yamanaka O. Epithelial basement membrane in alkali-burned corneas in rats. Immunohistochemical study. Cornea 1993; 12:383-90.
-
(1993)
Cornea
, vol.12
, pp. 383-390
-
-
Saika, S.1
Kobata, S.2
Hashizume, N.3
Okada, Y.4
Yamanaka, O.5
-
3
-
-
0035158373
-
Extracellular matrix components in a case of retrocorneal membrane associated with syphilitic interstitial keratitis
-
Kawaguchi R, Saika S, Wakayama M, Ooshima A, Ohnishi Y, Yabe H. Extracellular matrix components in a case of retrocorneal membrane associated with syphilitic interstitial keratitis. Cornea 2001; 20:100-3.
-
(2001)
Cornea
, vol.20
, pp. 100-103
-
-
Kawaguchi, R.1
Saika, S.2
Wakayama, M.3
Ooshima, A.4
Ohnishi, Y.5
Yabe, H.6
-
4
-
-
0036513626
-
The snail superfamily of zinc-finger transcription factors
-
Nieto MA. The snail superfamily of zinc-finger transcription factors. Nat Rev Mol Cell Biol 2002; 3:155-66.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 155-166
-
-
Nieto, M.A.1
-
5
-
-
0346724511
-
Epithelial-mesenchymal transition and its implications for fibrosis
-
Kalluri R, Neilson EG. Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest 2003; 112:1776-84.
-
(2003)
J Clin Invest
, vol.112
, pp. 1776-1784
-
-
Kalluri, R.1
Neilson, E.G.2
-
6
-
-
33750443652
-
FGF-2-mediated signal transduction during endothelial mesenchymal transformation in corneal endothelial cells
-
Lee JG, Kay EP. FGF-2-mediated signal transduction during endothelial mesenchymal transformation in corneal endothelial cells. Exp Eye Res 2006; 83:1309-16.
-
(2006)
Exp Eye Res
, vol.83
, pp. 1309-1316
-
-
Lee, J.G.1
Kay, E.P.2
-
7
-
-
39549089570
-
Connexin43 Knockdown Accelerates Wound Healing but Inhibits Mesenchymal Transition after Corneal Endothelial Injury In Vivo
-
Nakano Y, Oyamada M, Dai P, Nakagami T, Kinoshita S, Takamatu T. Connexin43 Knockdown Accelerates Wound Healing but Inhibits Mesenchymal Transition after Corneal Endothelial Injury In Vivo. Invest Ophthalmol Vis Sci 2008; 49:93-104.
-
(2008)
Invest Ophthalmol Vis Sci
, vol.49
, pp. 93-104
-
-
Nakano, Y.1
Oyamada, M.2
Dai, P.3
Nakagami, T.4
Kinoshita, S.5
Takamatu, T.6
-
8
-
-
45549091983
-
Epithelial-mesenchymal transition as a therapeutic target for prevention of ocular tissue fibrosis
-
Saika S, Yamanaka O, Flanders KC, Okada Y, Miyamoto T, Sumioka T, Shirai K, Kitano A, Miyazaki K, Tanaka S, Ikeda K. Epithelial-mesenchymal transition as a therapeutic target for prevention of ocular tissue fibrosis. Endocr Metab Immune Disord Drug Targets 2008; 8:69-76.
-
(2008)
Endocr Metab Immune Disord Drug Targets
, vol.8
, pp. 69-76
-
-
Saika, S.1
Yamanaka, O.2
Flanders, K.C.3
Okada, Y.4
Miyamoto, T.5
Sumioka, T.6
Shirai, K.7
Kitano, A.8
Miyazaki, K.9
Tanaka, S.10
Ikeda, K.11
-
9
-
-
40249088145
-
Fibrotic disorders in the eye: Targets of gene therapy
-
Saika S, Yamanaka O, Sumioka T, Miyamoto T, Miyazaki K, Okada Y, Kitano A, Shirai K, Tanaka S, Ikeda K. Fibrotic disorders in the eye: targets of gene therapy. Prog Retin Eye Res 2008; 27:177-96.
-
(2008)
Prog Retin Eye Res
, vol.27
, pp. 177-196
-
-
Saika, S.1
Yamanaka, O.2
Sumioka, T.3
Miyamoto, T.4
Miyazaki, K.5
Okada, Y.6
Kitano, A.7
Shirai, K.8
Tanaka, S.9
Ikeda, K.10
-
10
-
-
0346727324
-
Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubulointestinal fibrosis induced by unilaterall obstruction
-
Sato M, Muragaki Y, Saika S, Roberts AB, Ooshima A. Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubulointestinal fibrosis induced by unilaterall obstruction. J Clin Invest 2003; 112:1486-92.
-
(2003)
J Clin Invest
, vol.112
, pp. 1486-1492
-
-
Sato, M.1
Muragaki, Y.2
Saika, S.3
Roberts, A.B.4
Ooshima, A.5
-
11
-
-
33744944779
-
Epithelial origin of myofibroblasts during fibrosis in the lung
-
Willis BC, Borok ZTG. Epithelial origin of myofibroblasts during fibrosis in the lung. Proc Am Thorac Soc 2006; 3:377-82.
-
(2006)
Proc Am Thorac Soc
, vol.3
, pp. 377-382
-
-
Willis, B.C.1
Borok, Z.T.G.2
-
12
-
-
34547599359
-
Transforming growth factor-β 1 induces an epithelial-to-mesenchymal transition state in mouse hepatocytes in Vitro
-
Kaimori A, Potter J, Kaimori JY, Wang C, Mezey E, Koteish A. Transforming growth factor-β 1 induces an epithelial-to-mesenchymal transition state in mouse hepatocytes in Vitro. J Biol Chem 2007; 282:22089-101.
-
(2007)
J Biol Chem
, vol.282
, pp. 22089-22101
-
-
Kaimori, A.1
Potter, J.2
Kaimori, J.Y.3
Wang, C.4
Mezey, E.5
Koteish, A.6
-
13
-
-
30944439493
-
TGF beta pathobiology in the eye
-
Saika S. TGF beta pathobiology in the eye. Lab Invest 2006; 86:106-15.
-
(2006)
Lab Invest
, vol.86
, pp. 106-115
-
-
Saika, S.1
-
14
-
-
30944466813
-
Smad3 is key to TGF-beta-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis
-
Roberts AB, Tian F, Byfield SD, Stuelten C, Ooshima A, Saika S, Flanders KC. Smad3 is key to TGF-beta-mediated epithelial-to-mesenchymal transition, fibrosis, tumor suppression and metastasis. Cytokine Growth Factor Rev 2006; 17:19-27.
-
(2006)
Cytokine Growth Factor Rev
, vol.17
, pp. 19-27
-
-
Roberts, A.B.1
Tian, F.2
Byfield, S.D.3
Stuelten, C.4
Ooshima, A.5
Saika, S.6
Flanders, K.C.7
-
15
-
-
84868877186
-
Therapeutic effects of adenovirus-mediated gene transfer of TGF-β signal antagonists on undesirable epithelial-mesenchymal transition and neovascularization
-
Jakowlew SB, editor, Totawa NJ, Humana Press;
-
Saika S. Therapeutic effects of adenovirus-mediated gene transfer of TGF-β signal antagonists on undesirable epithelial-mesenchymal transition and neovascularization. In: Jakowlew SB, editor, Transforming growth factor-beta in cancer therapy. Volume II. Totawa (NJ): Humana Press; 2008.
-
(2008)
Transforming growth factor-beta in cancer therapy
, vol.2
-
-
Saika, S.1
-
16
-
-
1542289674
-
Smad3 signaling is required for epithelial-mesenchymal transition of lens epithelium after injury
-
Saika S, Kono-Saika S, Ohnishi Y, Sato M, Muragaki Y, Ooshima A, Flanders KC, Yoo J, Anzano M, Liu CY, Kao WWY, Roberts AB. Smad3 signaling is required for epithelial-mesenchymal transition of lens epithelium after injury. Am J Pathol 2004; 164:651-63.
-
(2004)
Am J Pathol
, vol.164
, pp. 651-663
-
-
Saika, S.1
Kono-Saika, S.2
Ohnishi, Y.3
Sato, M.4
Muragaki, Y.5
Ooshima, A.6
Flanders, K.C.7
Yoo, J.8
Anzano, M.9
Liu, C.Y.10
Kao, W.W.Y.11
Roberts, A.B.12
-
17
-
-
4944259825
-
Smad3 is required for dedifferentiation of retinal pigment epithelium following retinal detachment in mice
-
Saika S, Kono-Saika S, Tanaka T, Yamanaka O, Ohnishi Y, Sato M, Muragaki Y, Ooshima A, Yoo J, Flanders KC, Roberts AB. Smad3 is required for dedifferentiation of retinal pigment epithelium following retinal detachment in mice. Lab Invest 2004; 84:1245-58.
-
(2004)
Lab Invest
, vol.84
, pp. 1245-1258
-
-
Saika, S.1
Kono-Saika, S.2
Tanaka, T.3
Yamanaka, O.4
Ohnishi, Y.5
Sato, M.6
Muragaki, Y.7
Ooshima, A.8
Yoo, J.9
Flanders, K.C.10
Roberts, A.B.11
-
18
-
-
4944260347
-
Transient adenoviral gene transfer of Smad7 prevents injury-induced epithelial-mesenchymal transition of lens epithelium in mice
-
Saika S, Ikeda K, Yamanaka O, Sato M, Muragaki Y, Ohnishi Y, Ooshima A, Nakajima K, Kiyama H, Flanders KC, Roberts AB. Transient adenoviral gene transfer of Smad7 prevents injury-induced epithelial-mesenchymal transition of lens epithelium in mice. Lab Invest 2004; 84:1259-70.
-
(2004)
Lab Invest
, vol.84
, pp. 1259-1270
-
-
Saika, S.1
Ikeda, K.2
Yamanaka, O.3
Sato, M.4
Muragaki, Y.5
Ohnishi, Y.6
Ooshima, A.7
Nakajima, K.8
Kiyama, H.9
Flanders, K.C.10
Roberts, A.B.11
-
19
-
-
34248539392
-
Effect of Smad7 gene overexpression on transforming growth factor beta-induced retinal pigment fibrosis in a proliferative vitreoretinopathy mouse model
-
Saika S, Yamanaka O, Nishikawa-Ishida I, Kitano A, Flanders KC, Okada Y, Ohnishi Y, Nakajima Y, Ikeda K. Effect of Smad7 gene overexpression on transforming growth factor beta-induced retinal pigment fibrosis in a proliferative vitreoretinopathy mouse model. Arch Ophthalmol 2007; 125:647-54.
-
(2007)
Arch Ophthalmol
, vol.125
, pp. 647-654
-
-
Saika, S.1
Yamanaka, O.2
Nishikawa-Ishida, I.3
Kitano, A.4
Flanders, K.C.5
Okada, Y.6
Ohnishi, Y.7
Nakajima, Y.8
Ikeda, K.9
-
20
-
-
33646562542
-
The logic of TGF beta signaling
-
Massague J, Gomis RR. The logic of TGF beta signaling. FEBS Lett 2006; 580:2811-20.
-
(2006)
FEBS Lett
, vol.580
, pp. 2811-2820
-
-
Massague, J.1
Gomis, R.R.2
-
21
-
-
33847716712
-
Negative regulation of TGF-beta receptor/Smad signal transduction
-
Itoh S, ten Dijke P. Negative regulation of TGF-beta receptor/Smad signal transduction. Curr Opin Cell Biol 2007; 19:176-84.
-
(2007)
Curr Opin Cell Biol
, vol.19
, pp. 176-184
-
-
Itoh, S.1
ten Dijke, P.2
-
22
-
-
1442299193
-
Lateral signaling enhances TGF-beta response complexity
-
Byfield SD, Roberts AB. Lateral signaling enhances TGF-beta response complexity. Trends Cell Biol 2004; 14:107-11.
-
(2004)
Trends Cell Biol
, vol.14
, pp. 107-111
-
-
Byfield, S.D.1
Roberts, A.B.2
-
23
-
-
0036082554
-
Inhibition of transforming growth factor (TGF)-β1-induced extracellular matrix with a novel inhibitor of the TGF-β type I receptor kinase activity: SB-431542
-
Laping NJ, Grygielko E, Mathur A, Butter S, Bomberger J, Tweed C, Martin W, Fomwald J, Lehr R, Harling J, Gaster L, Callahan JF, Olson BA. Inhibition of transforming growth factor (TGF)-β1-induced extracellular matrix with a novel inhibitor of the TGF-β type I receptor kinase activity: SB-431542. Mol Pharmacol 2002; 62:58-64.
-
(2002)
Mol Pharmacol
, vol.62
, pp. 58-64
-
-
Laping, N.J.1
Grygielko, E.2
Mathur, A.3
Butter, S.4
Bomberger, J.5
Tweed, C.6
Martin, W.7
Fomwald, J.8
Lehr, R.9
Harling, J.10
Gaster, L.11
Callahan, J.F.12
Olson, B.A.13
-
24
-
-
20944448800
-
Expression of Smad7 in mouse eyes accelerates healing of corneal tissue following exposure to alkali
-
Saika S, Ikeda K, Yamanaka O, Miyamoto T, Ohnishi Y, Sato M, Muragaki Y, Ooshima A, Nakajima Y, Kao WWY, Flanders KC, Roberts AB. Expression of Smad7 in mouse eyes accelerates healing of corneal tissue following exposure to alkali. Am J Pathol 2005; 166:1405-18.
-
(2005)
Am J Pathol
, vol.166
, pp. 1405-1418
-
-
Saika, S.1
Ikeda, K.2
Yamanaka, O.3
Miyamoto, T.4
Ohnishi, Y.5
Sato, M.6
Muragaki, Y.7
Ooshima, A.8
Nakajima, Y.9
Kao, W.W.Y.10
Flanders, K.C.11
Roberts, A.B.12
-
25
-
-
20944442872
-
Therapeutic effect of topical administration of SN50, an inhibitor of nuclear factor-kappaB, in treatment of corneal alkali burns in mice
-
Saika S, Miyamoto T, Yamanaka O, Kato T, Ohnishi Y, Flanders KC, Ikeda K, Nakajima Y, Kao WW, Sato M, Muragaki Y, Ooshima A. Therapeutic effect of topical administration of SN50, an inhibitor of nuclear factor-kappaB, in treatment of corneal alkali burns in mice. Am J Pathol 2005; 166:1393-403.
-
(2005)
Am J Pathol
, vol.166
, pp. 1393-1403
-
-
Saika, S.1
Miyamoto, T.2
Yamanaka, O.3
Kato, T.4
Ohnishi, Y.5
Flanders, K.C.6
Ikeda, K.7
Nakajima, Y.8
Kao, W.W.9
Sato, M.10
Muragaki, Y.11
Ooshima, A.12
-
26
-
-
22544457471
-
Inhibition of p38MAP kinase suppresses fibrotic reaction of retinal pigment epithelial cells
-
Saika S, Yamanaka O, Ikeda K, Kim-Mitsuyama S, Flanders KC, Yoo J, Roberts AB, Nishikawa-Ishida I, Ohnishi Y, Muragaki Y, Ooshima A. Inhibition of p38MAP kinase suppresses fibrotic reaction of retinal pigment epithelial cells. Lab Invest 2005; 85:838-50.
-
(2005)
Lab Invest
, vol.85
, pp. 838-850
-
-
Saika, S.1
Yamanaka, O.2
Ikeda, K.3
Kim-Mitsuyama, S.4
Flanders, K.C.5
Yoo, J.6
Roberts, A.B.7
Nishikawa-Ishida, I.8
Ohnishi, Y.9
Muragaki, Y.10
Ooshima, A.11
-
27
-
-
12544257249
-
Role of Rho/ROCK and p38 MAP kinase pathways in transforming growth factor-beta-mediated Smad-dependent growth inhibition of human breast carcinoma cells in vivo
-
Kamaraju AK, Roberts AB. Role of Rho/ROCK and p38 MAP kinase pathways in transforming growth factor-beta-mediated Smad-dependent growth inhibition of human breast carcinoma cells in vivo. J Biol Chem 2005; 280:1024-36.
-
(2005)
J Biol Chem
, vol.280
, pp. 1024-1036
-
-
Kamaraju, A.K.1
Roberts, A.B.2
-
28
-
-
34347235524
-
Reversible Smad-dependent signaling between tumor suppression and oncogenesis
-
Sekimoto G, Matsuzaki K, Yoshida K, Mori S, Murata M, Seki T, Matsui H, Fujisawa J, Okazaki K. Reversible Smad-dependent signaling between tumor suppression and oncogenesis. Cancer Res 2007; 67:5090-6.
-
(2007)
Cancer Res
, vol.67
, pp. 5090-5096
-
-
Sekimoto, G.1
Matsuzaki, K.2
Yoshida, K.3
Mori, S.4
Murata, M.5
Seki, T.6
Matsui, H.7
Fujisawa, J.8
Okazaki, K.9
-
29
-
-
20144379460
-
Smad pathway-specific transcriptional regulation of the cell cycle inhibitor p21(WAF1/Cip1)
-
Pardali K, Kowanetz M, Heldin CH, Moustakas A. Smad pathway-specific transcriptional regulation of the cell cycle inhibitor p21(WAF1/Cip1). J Cell Physiol 2005; 204:260-72.
-
(2005)
J Cell Physiol
, vol.204
, pp. 260-272
-
-
Pardali, K.1
Kowanetz, M.2
Heldin, C.H.3
Moustakas, A.4
-
30
-
-
20444433569
-
Smad7 abrogates transforming growth factor-beta1-mediated growth inhibition in COLO-357 cells through functional inactivation of the retinoblastoma protein
-
Boyer Arnold N, Korc M. Smad7 abrogates transforming growth factor-beta1-mediated growth inhibition in COLO-357 cells through functional inactivation of the retinoblastoma protein. J Biol Chem 2005; 280:21858-66.
-
(2005)
J Biol Chem
, vol.280
, pp. 21858-21866
-
-
Boyer Arnold, N.1
Korc, M.2
-
31
-
-
3543028591
-
FGF-2 induced by interleukin-1 beta through the action of phosphatidylinositol 3-kinase endothelial mesenchymal transformation in corneal endothelial cells
-
Lee HT, Lee JG, Na M, Kay EP. FGF-2 induced by interleukin-1 beta through the action of phosphatidylinositol 3-kinase endothelial mesenchymal transformation in corneal endothelial cells. J Biol Chem 2004; 279:32325-32.
-
(2004)
J Biol Chem
, vol.279
, pp. 32325-32332
-
-
Lee, H.T.1
Lee, J.G.2
Na, M.3
Kay, E.P.4
-
32
-
-
0036233040
-
Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation
-
Strutz F, Zeisberg M, Ziyadeh FN, Yang CQ, Kalluri R, Muller GA, Neilson EG. Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation. Kidney Int 2002; 61:1714-28.
-
(2002)
Kidney Int
, vol.61
, pp. 1714-1728
-
-
Strutz, F.1
Zeisberg, M.2
Ziyadeh, F.N.3
Yang, C.Q.4
Kalluri, R.5
Muller, G.A.6
Neilson, E.G.7
|