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Volumn 207, Issue 9, 2010, Pages 1819-1823

Sliding set-points of immune responses for therapy of autoimmunity

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIBODY; HLA ANTIGEN; INTERLEUKIN 2; T LYMPHOCYTE RECEPTOR;

EID: 77956259249     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20101606     Document Type: Short Survey
Times cited : (5)

References (31)
  • 1
    • 65749120321 scopus 로고    scopus 로고
    • Intraclonal competition limits the fate determination of regulatory T cells in the thymus
    • doi:10.1038/ni.1739
    • Bautista, J.L., C.W. Lio, S.K. Lathrop, K. Forbush, Y. Liang, J. Luo, A.Y. Rudensky, and C.S. Hsieh. 2009. Intraclonal competition limits the fate determination of regulatory T cells in the thymus. Nat. Immunol. 10:610-617. doi:10.1038/ni.1739
    • (2009) Nat. Immunol. , vol.10 , pp. 610-617
    • Bautista, J.L.1    Lio, C.W.2    Lathrop, S.K.3    Forbush, K.4    Liang, Y.5    Luo, J.6    Rudensky, A.Y.7    Hsieh, C.S.8
  • 2
    • 77951776390 scopus 로고    scopus 로고
    • Genetics, pathogenesis and clinical interventions in type 1 diabetes
    • doi:10.1038/nature08933
    • Bluestone, J.A., K. Herold, and G. Eisenbarth. 2010. Genetics, pathogenesis and clinical interventions in type 1 diabetes. Nature. 464: 1293-1300. doi:10.1038/nature08933
    • (2010) Nature , vol.464 , pp. 1293-1300
    • Bluestone, J.A.1    Herold, K.2    Eisenbarth, G.3
  • 3
    • 37849008688 scopus 로고    scopus 로고
    • Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire
    • doi:10.1016/j.immuni.2007.11.022
    • Burchill, M.A., J. Yang, K.B. Vang, J.J. Moon, H.H. Chu, C.W. Lio, A.L. Vegoe, C.S. Hsieh, M.K. Jenkins, and M.A. Farrar. 2008. Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire. Immunity. 28:112-121. doi:10.1016/j.immuni.2007.11.022
    • (2008) Immunity , vol.28 , pp. 112-121
    • Burchill, M.A.1    Yang, J.2    Vang, K.B.3    Moon, J.J.4    Chu, H.H.5    Lio, C.W.6    Vegoe, A.L.7    Hsieh, C.S.8    Jenkins, M.K.9    Farrar, M.A.10
  • 5
    • 27544446622 scopus 로고    scopus 로고
    • Development and function of agonist-induced CD25+ Foxp3+ regulatory T cells in the absence of interleukin 2 signaling
    • doi:10.1038/ni1264
    • D'Cruz, L.M., and L. Klein. 2005. Development and function of agonist-induced CD25+ Foxp3+ regulatory T cells in the absence of interleukin 2 signaling. Nat. Immunol. 6: 1152-1159. doi:10.1038/ni1264
    • (2005) Nat. Immunol. , vol.6 , pp. 1152-1159
    • D'Cruz, L.M.1    Klein, L.2
  • 6
    • 65449125930 scopus 로고    scopus 로고
    • Natural Treg cells spontaneously differentiate into pathogenic helper cells in lymphopenic conditions
    • doi:10.1002/eji.200839196
    • Duarte, J.H., S. Zelenay, M.L. Bergman, A.C. Martins, and J. Demengeot. 2009. Natural Treg cells spontaneously differentiate into pathogenic helper cells in lymphopenic conditions. Eur. J. Immunol. 39:948-955. doi:10.1002/eji.200839196
    • (2009) Eur. J. Immunol. , vol.39 , pp. 948-955
    • Duarte, J.H.1    Zelenay, S.2    Bergman, M.L.3    Martins, A.C.4    Demengeot, J.5
  • 7
    • 27544481941 scopus 로고    scopus 로고
    • A function for interleukin 2 in Foxp3-expressing regulatory T cells
    • doi:10.1038/ni1263
    • Fontenot, J.D., J.P. Rasmussen, M.A. Gavin, and A.Y. Rudensky. 2005. A function for interleukin 2 in Foxp3-expressing regulatory T cells. Nat. Immunol. 6:1142-1151. doi:10.1038/ni1263
    • (2005) Nat. Immunol. , vol.6 , pp. 1142-1151
    • Fontenot, J.D.1    Rasmussen, J.P.2    Gavin, M.A.3    Rudensky, A.Y.4
  • 9
    • 33645102841 scopus 로고    scopus 로고
    • An intersection between the self-reactive regulatory and non-regulatory T cell receptor repertoires
    • doi:10.1038/ni1318
    • Hsieh, C.S., Y. Zheng, Y. Liang, J.D. Fontenot, and A.Y. Rudensky. 2006. An intersection between the self-reactive regulatory and non-regulatory T cell receptor repertoires. Nat. Immunol. 7:401-410. doi:10.1038/ni1318
    • (2006) Nat. Immunol. , vol.7 , pp. 401-410
    • Hsieh, C.S.1    Zheng, Y.2    Liang, Y.3    Fontenot, J.D.4    Rudensky, A.Y.5
  • 10
    • 27944455288 scopus 로고    scopus 로고
    • Sequential development of interleukin 2-dependent effector and regulatory T cells in response to endogenous systemic antigen
    • doi:10.1084/jem.20050855
    • Knoechel, B., J. Lohr, E. Kahn, J.A. Bluestone, and A.K. Abbas. 2005. Sequential development of interleukin 2-dependent effector and regulatory T cells in response to endogenous systemic antigen. J. Exp. Med. 202:1375-1386. doi:10.1084/jem.20050855
    • (2005) J. Exp. Med. , vol.202 , pp. 1375-1386
    • Knoechel, B.1    Lohr, J.2    Kahn, E.3    Bluestone, J.A.4    Abbas, A.K.5
  • 12
    • 59649118664 scopus 로고    scopus 로고
    • Antigen-specific peripheral shaping of the natural regulatory T cell population
    • doi:10.1084/jem.20081359
    • Lathrop, S.K., N.A. Santacruz, D. Pham, J. Luo, and C.S. Hsieh. 2008. Antigen-specific peripheral shaping of the natural regulatory T cell population. J. Exp. Med. 205:3105-3117. doi:10.1084/jem.20081359
    • (2008) J. Exp. Med. , vol.205 , pp. 3105-3117
    • Lathrop, S.K.1    Santacruz, N.A.2    Pham, D.3    Luo, J.4    Hsieh, C.S.5
  • 13
    • 70350440009 scopus 로고    scopus 로고
    • + cells is limited to small clonal sizes
    • doi:10.1084/jem.20091033
    • + cells is limited to small clonal sizes. J. Exp. Med. 206:2121-2130. doi:10.1084/jem.20091033
    • (2009) J. Exp. Med. , vol.206 , pp. 2121-2130
    • Leung, M.W.1    Shen, S.2    Lafaille, J.J.3
  • 14
    • 33748448717 scopus 로고    scopus 로고
    • Transforming growth factor-beta controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanisms
    • doi:10.1016/j.immuni.2006.07.011
    • Li, M.O., S. Sanjabi, and R.A. Flavell. 2006. Transforming growth factor-beta controls development, homeostasis, and tolerance of T cells by regulatory T cell-dependent and -independent mechanisms. Immunity. 25:455-471. doi:10.1016/j.immuni.2006.07.011
    • (2006) Immunity , vol.25 , pp. 455-471
    • Li, M.O.1    Sanjabi, S.2    Flavell, R.A.3
  • 15
    • 37849009964 scopus 로고    scopus 로고
    • A two-step process for thymic regulatory T cell development
    • doi:10.1016/j.immuni.2007.11.021
    • Lio, C.W., and C.S. Hsieh. 2008. A two-step process for thymic regulatory T cell development. Immunity. 28:100-111. doi:10.1016/j.immuni.2007.11.021
    • (2008) Immunity , vol.28 , pp. 100-111
    • Lio, C.W.1    Hsieh, C.S.2
  • 16
    • 41949097030 scopus 로고    scopus 로고
    • The biology of interleukin-2
    • doi:10.1146/annurev.immunol.26.021607.090357
    • Malek, T.R. 2008. The biology of interleukin-2. Annu. Rev. Immunol. 26:453-479. doi:10.1146/annurev.immunol.26.021607.090357
    • (2008) Annu. Rev. Immunol. , vol.26 , pp. 453-479
    • Malek, T.R.1
  • 17
    • 0036669298 scopus 로고    scopus 로고
    • CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2
    • doi:10.1016/S1074-7613(02)00367-9
    • Malek, T.R., A. Yu, V. Vincek, P. Scibelli, and L. Kong. 2002. CD4 regulatory T cells prevent lethal autoimmunity in IL-2Rbeta-deficient mice. Implications for the nonredundant function of IL-2. Immunity. 17:167-178. doi:10.1016/S1074-7613(02)00367-9
    • (2002) Immunity , vol.17 , pp. 167-178
    • Malek, T.R.1    Yu, A.2    Vincek, V.3    Scibelli, P.4    Kong, L.5
  • 18
    • 33748465396 scopus 로고    scopus 로고
    • Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor
    • doi:10.1016/j.immuni.2006.07.012
    • Marie, J.C., D. Liggitt, and A.Y. Rudensky. 2006. Cellular mechanisms of fatal early-onset autoimmunity in mice with the T cell-specific targeting of transforming growth factor-beta receptor. Immunity. 25:441-454. doi:10.1016/j.immuni.2006.07.012
    • (2006) Immunity , vol.25 , pp. 441-454
    • Marie, J.C.1    Liggitt, D.2    Rudensky, A.Y.3
  • 19
    • 77956254994 scopus 로고    scopus 로고
    • Anti-CD3 therapy permits regulatory T cells to surmount T cell receptor-specified peripheral niche constraints
    • Nishio, J., M. Feuerer, J. Wong, D. Mathis, and C. Benoist. 2010. Anti-CD3 therapy permits regulatory T cells to surmount T cell receptor-specified peripheral niche constraints. J. Exp. Med. 207:1879-1889.
    • (2010) J. Exp. Med. , vol.207 , pp. 1879-1889
    • Nishio, J.1    Feuerer, M.2    Wong, J.3    Mathis, D.4    Benoist, C.5
  • 21
    • 33747099523 scopus 로고    scopus 로고
    • Origin and T cell receptor diversity of Foxp3+CD4+CD25+ T cells
    • doi:10.1016/j.immuni.2006.05.016
    • Pacholczyk, R., H. Ignatowicz, P. Kraj, and L. Ignatowicz. 2006. Origin and T cell receptor diversity of Foxp3+CD4+CD25+ T cells. Immunity. 25:249-259. doi:10.1016/j.immuni.2006.05.016
    • (2006) Immunity , vol.25 , pp. 249-259
    • Pacholczyk, R.1    Ignatowicz, H.2    Kraj, P.3    Ignatowicz, L.4
  • 22
    • 36248976097 scopus 로고    scopus 로고
    • CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells
    • doi:10.1038/ni1536
    • Pandiyan, P., L. Zheng, S. Ishihara, J. Reed, and M.J. Lenardo. 2007. CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells. Nat. Immunol. 8:1353-1362. doi:10.1038/ni1536
    • (2007) Nat. Immunol. , vol.8 , pp. 1353-1362
    • Pandiyan, P.1    Zheng, L.2    Ishihara, S.3    Reed, J.4    Lenardo, M.J.5
  • 23
    • 0037436119 scopus 로고    scopus 로고
    • Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells
    • doi:10.1126/science.1078231
    • Pasare, C., and R. Medzhitov. 2003. Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells. Science. 299:1033-1036. doi:10.1126/science.1078231
    • (2003) Science , vol.299 , pp. 1033-1036
    • Pasare, C.1    Medzhitov, R.2
  • 25
    • 34547214205 scopus 로고    scopus 로고
    • Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans
    • doi:10.1038/nri2138
    • Roncarolo, M.G., and M. Battaglia. 2007. Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans. Nat. Rev. Immunol. 7:585-598. doi:10.1038/nri2138
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 585-598
    • Roncarolo, M.G.1    Battaglia, M.2
  • 26
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi, S., N. Sakaguchi, M. Asano, M. Itoh, and M. Toda. 1995. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol. 155:1151-1164.
    • (1995) J. Immunol. , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 27
    • 77953308663 scopus 로고    scopus 로고
    • - precursor to Foxp3+ regulatory T cells in peripheral lymphoid organs of nonmanipulated mice
    • doi:10.1084/jem.20100045
    • - precursor to Foxp3+ regulatory T cells in peripheral lymphoid organs of nonmanipulated mice. J. Exp. Med. 207:1393-1407. doi:10.1084/jem.20100045
    • (2010) J. Exp. Med. , vol.207 , pp. 1393-1407
    • Schallenberg, S.1    Tsai, P.Y.2    Riewaldt, J.3    Kretschmer, K.4
  • 28
    • 77953696525 scopus 로고    scopus 로고
    • EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs
    • doi:10.1136/ard.2009.126532
    • Smolen, J.S., R. Landewé, F.C. Breedveld, M. Dougados, P. Emery, C. Gaujoux-Viala, S. Gorter, R. Knevel, J. Nam, M. Schoels, et al. 2010. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs. Ann. Rheum. Dis. 69: 964-975. doi:10.1136/ard.2009.126532
    • (2010) Ann. Rheum. Dis. , vol.69 , pp. 964-975
    • Smolen, J.S.1    Landewé, R.2    Breedveld, F.C.3    Dougados, M.4    Emery, P.5    Gaujoux-Viala, C.6    Gorter, S.7    Knevel, R.8    Nam, J.9    Schoels, M.10
  • 30
    • 43049174722 scopus 로고    scopus 로고
    • Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction
    • doi:10.1016/j.immuni.2008.03.016
    • Tang, Q., J.Y. Adams, C. Penaranda, K. Melli, E. Piaggio, E. Sgouroudis, C.A. Piccirillo, B.L. Salomon, and J.A. Bluestone. 2008. Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction. Immunity. 28:687-697. doi:10.1016/j.immuni.2008.03.016
    • (2008) Immunity , vol.28 , pp. 687-697
    • Tang, Q.1    Adams, J.Y.2    Penaranda, C.3    Melli, K.4    Piaggio, E.5    Sgouroudis, E.6    Piccirillo, C.A.7    Salomon, B.L.8    Bluestone, J.A.9
  • 31
    • 2942692039 scopus 로고    scopus 로고
    • + T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes
    • doi:10.1084/jem.20040180
    • + T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes. J. Exp. Med. 199:1467-1477. doi:10.1084/jem.20040180
    • (2004) J. Exp. Med. , vol.199 , pp. 1467-1477
    • Tarbell, K.V.1    Yamazaki, S.2    Olson, K.3    Toy, P.4    Steinman, R.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.