Hispolon suppresses SK-Hep1 human hepatoma cell metastasis by inhibiting matrix metalloproteinase-2/9 and urokinase-plasminogen activator through the PI3K/Akt and ERK signaling pathways

Journal of Agricultural and Food Chemistry

Volumn 58, Issue 17, 2010, Pages 9468-9475

  Huang, Guan Jhong ^a   Yang, Chih Min ^b   Chang, Yuan Shiun ^a   Amagaya, Sakae ^c   Wang, Hsiao Chieh ^a   Hou, Wen Chi ^d   Huang, Shyh Shyun ^a   Hu, Miao Lin ^a,b  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^c NIHON PHARMACEUTICAL UNIVERSITY   (Japan)

^d TAIPEI MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Hispolon; MMP 2; MMP 9; Phellinus linteus; uPA

Indexed keywords

HISPOLON; MMP-2; MMP-9; PHELLINUS LINTEUS; UPA;

ADHESION; DISEASES; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYMES; PATHOLOGY; PHENOLS; PHOSPHORYLATION; PIGMENTS; SIGNALING;

GENE EXPRESSION;

CATECHOL DERIVATIVE; HISPOLON; MATRIX METALLOPROTEINASE; PROTEIN KINASE; UROKINASE;

ARTICLE; CELL ADHESION; CELL MOTION; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; HUMAN; LIVER CELL CARCINOMA; LIVER TUMOR; METABOLISM; METASTASIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

CARCINOMA, HEPATOCELLULAR; CATECHOLS; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; HUMANS; LIVER NEOPLASMS; MAGNETIC RESONANCE SPECTROSCOPY; MATRIX METALLOPROTEINASES; NEOPLASM METASTASIS; PROTEIN KINASES; SIGNAL TRANSDUCTION; UROKINASE-TYPE PLASMINOGEN ACTIVATOR;

BASIDIOMYCOTA; INONOTUS LINTEUS;

EID: 77956243391     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf101508r     Document Type: Article

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