The risk of hip fractures in older individuals with diabetes: A population-based study

Diabetes Care

Volumn 30, Issue 4, 2007, Pages 835-841

  Lipscombe, Lorraine L ^a,b,c   Jamal, Sophie A ^b,c,e   Booth, Gillian L ^a,b,d,e   Hawker, Gillian A ^a,b,c,e  

^a INSTITUTE FOR CLINICAL EVALUATIVE SCIENCES   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c WOMEN S COLLEGE HOSPITAL   (Canada)

^d ST MICHAEL'S HOSPITAL   (Canada)

^e UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICONVULSIVE AGENT; ANTIDEPRESSANT AGENT; ANTIPARKINSON AGENT; BARBITURIC ACID DERIVATIVE; BENZODIAZEPINE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BISPHOSPHONIC ACID DERIVATIVE; BROMOCRIPTINE; CHLORAL HYDRATE; CODEINE; CORTICOSTEROID; ESTROGEN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LEVODOPA; MORPHINE; NITRIC ACID DERIVATIVE; PERGOLIDE; PRAMIPEXOLE; ROPINIROLE; SEDATIVE AGENT; SEROTONIN UPTAKE INHIBITOR; THIAZIDE DIURETIC AGENT; TRANQUILIZER;

AGED; ARTICLE; BONE DENSITY; COMORBIDITY; CONTROLLED STUDY; DEMOGRAPHY; DISEASE REGISTRY; FALLING; FEMALE; FOLLOW UP; HIP FRACTURE; HUMAN; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; PHYSICIAN; PREVALENCE; RISK FACTOR; SIDE EFFECT;

AGED; BONE DENSITY; COHORT STUDIES; COMORBIDITY; DATABASES, FACTUAL; DIABETES COMPLICATIONS; HIP FRACTURES; HUMANS; MEDICAL RECORDS; ONTARIO; PATIENT SELECTION; RETROSPECTIVE STUDIES; RISK FACTORS;

EID: 34147176168     PISSN: 01495992     EISSN: 01495992     Source Type: Journal    
DOI: 10.2337/dc06-1851     Document Type: Article

References (47)

1. Chrischilles EA, Butler CD, Davis CS, Wallace RB: A model of lifetime osteoporosis impact. Arch Intern Med 151:2026-2032, 1991
2. Ivers RQ, Cumming RG, Mitchell P, Peduto AJ: Diabetes and risk of fracture: the Blue Mountains Eye Study. Diabetes Care 24:1198-1203, 2001
3. Strotmeyer ES, Cauley JA, Orchard TJ, Steenkiste AR, Dorman JS: Middle-aged premenopausal women with type 1 diabetes have lower bone mineral density and calcaneal quantitative ultrasound than nondiabetic women. Diabetes Care 29:306-311, 2006
4. Ahmed LA, Joakimsen RM, Berntsen GK, Fonnebo V, Schirmer H: Diabetes mellitus and the risk of non-vertebral fractures: the Tromso study. Osteoporos Int 17:495-500, 2006
5. Forsen L, Meyer HE, Midthjell K, Edna TH: Diabetes mellitus and the incidence of hip fracture: results from the Nord-Trondelag Health Survey. Diabetologia 42:920-925, 1999
6. Nicodemus KK, Folsom AR: Type 1 and type 2 diabetes and incident hip fractures in postmenopausal women. Diabetes Care 24:1192-1197, 2001
7. Vestergaard P, Rejnmark L, Mosekilde L: Relative fracture risk in patients with diabetes mellitus, and the impact of insulin and oral antidiabetic medication on relative fracture risk. Diabetologia 48:1292-1299, 2005
8. Christensen JO, Svendsen OL: Bone mineral in pre- and postmenopausal women with insulin-dependent and non-insulin-dependent diabetes mellitus. Osteoporos Int 10:307-311, 1999
9. van Daele PL, Stolk RP, Burger H, Algra D, Grobbee DE, Hofman A, Birkenhager JC, Pols HA: Bone density in non-insulin-dependent diabetes mellitus: the Rotterdam Study. Ann Intern Med 122:409-414, 1995
10. Weinstock RS, Goland RS, Shane E, Clemens TL, Lindsay R, Bilezikian JP: Bone mineral density in women with type II diabetes mellitus. J Bone Miner Res 4:97-101, 1989
11. Melchior TM, Sorensen H, Torp-Pedersen C: Hip and distal arm fracture rates in peri- and postmenopausal insulin-treated diabetic females. J Intern Med 236:203-208, 1994
12. Heath H III, Melton LJ III, Chu CP: Diabetes mellitus and risk of skeletal fracture. N Engl J Med 303:567-570, 1980
13. de Liefde II, van der Klift M, de Laet CE, van Daele PL, Hofman A, Pols HA: Bone mineral density and fracture risk in type-2 diabetes mellitus: the Rotterdam Study. Osteoporos Int 16:1713-1720, 2005
14. Ottenbacher KJ, Ostir GV, Peek MK, Goodwin JS, Markides KS: Diabetes mellitus as a risk factor for hip fracture in Mexican American older adults. J Gerontol A Biol Sci Med Sci 57:M648-M653, 2002
15. Schwartz AV, Sellmeyer DE, Ensrud KE, Cauley JA, Tabor HK, Schreiner PJ, Jamal SA, Black DM, Cummings SR: Older women with diabetes have an increased risk of fracture: a prospective study. J Clin Endocrinol Metab 86:32-38, 2001
16. Strotmeyer ES, Cauley JA, Schwartz AV, Nevitt MC, Resnick HE, Bauer DC, Tylavsky FA, de Rekeneire N, Harris TB, Newman AB: Nontraumatic fracture risk with diabetes mellitus and impaired fasting glucose in older white and black adults: the health, aging, and body composition study. Arch Intern Med 165:1612-1617, 2005
17. Kriegsman DM, Penninx BW, van Eijk JT, Boeke AJ, Deeg DJ: Self-reports and general practitioner information on the presence of chronic diseases in community dwelling elderly: a study on the accuracy of patients' self-reports and on determinants of inaccuracy. J Clin Epidemiol 49:1407-1417, 1996
18. Hux JE, Ivis F, Flintoft V, Bica A: Diabetes in Ontario: determination of prevalence and incidence using a validated administrative data algorithm. Diabetes Care 25:512-516, 2002
19. Cummings SR, Nevitt MC, Browner WS, Stone K, Fox KM, Ensrud KE, Cauley J, Black D, Vogt TM: Risk factors for hip fracture in white women: study of Osteoporotic Fractures Research Group. N Engl J Med 332:767-773, 1995
20. Rossouw JE, Anderson GL, Prentice RL, LaCroix AZ, Kooperberg C, Stefanick ML, Jackson RD, Beresford SA, Howard BV, Johnson KC, Kotchen JM, Ockene J: Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women's Health Initiative randomized controlled trial. JAMA 288:321-333, 2002
21. Bauer DC, Mundy GR, Jamal SA, Black DM, Cauley JA, Ensrud KE, van der KM, Pols HA: Use of statins and fracture: results of 4 prospective studies and cumulative meta-analysis of observational studies and controlled trials. Arch Intern Med 164:146-152, 2004
22. Jamal SA, Browner WS, Bauer DC, Cummings SR: Intermittent use of nitrates increases bone mineral density: the study of osteoporotic fractures. J Bone Miner Res 13:1755-1759, 1998
23. Liu B, Anderson G, Mittmann N, To T, Axcell T, Shear N: Use of selective serotonin-reuptake inhibitors of tricyclic antidepressants and risk of hip fractures in elderly people. Lancet 351:1303-1307, 1998
24. Rejnmark L, Vestergaard P, Mosekilde L: Reduced fracture risk in users of thiazide diuretics. Calcif Tissue Int 76:167-175, 2005
25. Vestergaard P, Rejnmark L, Mosekilde L: Fracture risk associated with systemic and topical corticosteroids. J Intern Med 257:374-384, 2005
26. Wilkins R: Automated geographic coding based on the Statistics Canada postal code conversion files, including postal codes to May 2002 (Catalogue 82 F0086-XDB). Ottawa, Health Analysis and Measurement Group, Statistics Canada, July 2002
27. Weiner JP, Starfield BH, Steinwachs DM, Mumford LM: Development and application of a population-oriented measure of ambulatory care case-mix. Med Care 29:452-472, 1991
28. Kanis J, Oden A, Johnell O: Acute and long-term increase in fracture risk after hospitalization for stroke. Stroke 32:702-706, 2001
29. Melton LJ III, Brown RD Jr, Achenbach SJ, O'Fallon WM, Whisnant JP: Long-term fracture risk following ischemic stroke: a population-based study. Osteoporos Int 12:980-986, 2001
30. Richardson JK, Ashton-Miller JA: Peripheral neuropathy: an often-overlooked cause of falls in the elderly. Postgrad Med 99:161-172, 1996
31. Richardson JK: Factors associated with falls in older patients with diffuse polyneuropathy. J Am Geriatr Soc 50:1767-1773, 2002
32. Miller WC, Speechley M, Deathe B: The prevalence and risk factors of falling and fear of falling among lower extremity amputees. Arch Phys Med Rehabil 82:1031-1037, 2001
33. Lipscombe LL, Hux JE, Booth GL: Reduced screening mammography among women with diabetes. Arch Intern Med 165:2090-2095, 2005
34. Roos LL, Stranc L, James RC, Li J: Complications, comorbidities, and mortality: improving classification and prediction. Health Serv Res 32:229-238, 1997
35. Feldstein AC, Nichols G, Orwoll E, Elmer PJ, Smith DH, Herson M, Aickin M: The near absence of osteoporosis treatment in older men with fractures. Osteoporos Int 16:953-962, 2005
36. Cauley JA, Lui LY, Ensrud KE, Zmuda JM, Stone KL, Hochberg MC, Cummings SR: Bone mineral density and the risk of incident nonspinal fractures in black and white women. JAMA 293:2102-2108, 2005
37. Greenspan SL, Myers ER, Maitland LA, Resnick NM, Hayes WC: Fall severity and bone mineral density as risk factors for hip fracture in ambulatory elderly. JAMA 271:128-133, 1994
38. Greenspan SL, Myers ER, Kiel DP, Parker RA, Hayes WC, Resnick NM: Fall direction, bone mineral density, and function: risk factors for hip fracture in frail nursing home elderly. Am J Med 104:539-545, 1998
39. Wei TS, Hu CH, Wang SH, Hwang KL: Fall characteristics, functional mobility and bone mineral density as risk factors of hip fracture in the community-dwelling ambulatory elderly. Osteoporos Int 12:1050-1055, 2001
40. Christiansen C, Christensen MS, McNair P, Nielsen B, Madsbad S: Vitamin D metabolites in diabetic patients: decreased serum concentration of 24,25-dihydroxyvitamin D. Scand J Clin Lab Invest 42:487-491, 1982
41. Nyomba BL, Verhaeghe J, Thomasset M, Lissens W, Bouillon R: Bone mineral homeostasis in spontaneously diabetic BB rats. I. Abnormal vitamin D metabolism and impaired active intestinal calcium absorption. Endocrinology 124:565-572, 1989
42. Paul RG, Bailey AJ: Glycation of collagen: the basis of its central role in the late complications of ageing and diabetes. Int J Biochem Cell Biol 28:1297-1310, 1996
43. Vashishth D, Gibson GJ, Khoury JI, Schaf-fler MB, Kimura J, Fyhrie DP: Influence of nonenzymatic glycation on biomechanical properties of cortical bone. Bone 28:195-201, 2001
44. Balint E, Szabo P, Marshall CF, Sprague SM: Glucose-induced inhibition of in vitro bone mineralization. Bone 28:21-28, 2001
45. Thrailkill KM, Lumpkin CK Jr, Bunn RC, Kemp SF, Fowlkes JL: Is insulin an anabolic agent in bone? Dissecting the diabetic bone for clues. Am J Physiol 289:E735-E745, 2005
46. Yano H, Ohya K, Amagasa T: Effects of insulin on in vitro bone formation in fetal rat parietal bone. Endocr J 41:293-300, 1994
47. Wild S, Roglic G, Green A, Sicree R, King H: Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 27:1047-1053, 2004