Effects of glucose and its modulation by insulin and estradiol on BMSC differentiation into osteoblastic lineages

Biochemistry and Cell Biology

Volumn 84, Issue 1, 2006, Pages 93-101

  Gopalakrishnan, V ^a   Vignesh, R C ^a   Arunakaran, J ^a   Aruldhas, M M ^a   Srinivasan, N ^a  

^a UNIVERSITY OF MADRAS   (India)

Author keywords

Bone marrow cells; Estradiol; Glucose; Insulin; Mineralization

Indexed keywords

ALCOHOLS; CELLS; COLLAGEN; INSULIN; MINERALS;

BONE MARROW CELLS; ESTRADIOL; MINERALIZATION;

GLUCOSE;

ALKALINE PHOSPHATASE; COLLAGEN; ESTRADIOL; GLUCOSE; INSULIN; THYMIDINE;

ANIMAL CELL; ARTICLE; BONE MARROW; BONE MINERALIZATION; CELL DIFFERENTIATION; CELL PROLIFERATION; HISTOCHEMISTRY; NONHUMAN; OSTEOBLAST; RAT; STROMA CELL;

ALKALINE PHOSPHATASE; ANIMALS; BONE MARROW CELLS; CALCIFICATION, PHYSIOLOGIC; CELL DIFFERENTIATION; CELL LINEAGE; CELLS, CULTURED; ESTRADIOL; EXTRACELLULAR MATRIX; GLUCOSE; INSULIN; OSTEOBLASTS; RATS; STROMAL CELLS; THYMIDINE; TRITIUM;

ANIMALIA;

EID: 33645409010     PISSN: 08298211     EISSN: None     Source Type: Journal    
DOI: 10.1139/o05-163     Document Type: Article

References (58)

1. Akune, T., Ogata, N., Hoshi, K., Kubota, N., Terauchi, Y., Tobe, K. et al. 2002. Insulin receptor substrate-2 maintains predominance of anabolic function over catabolic function of osteoblasts. J. Cell Biol. 159: 147-156.
2. Allen, D.A., Harwood, S., Varagunam, M., Raftery, M.J., and Yaqoob, M.M. 2003. High glucose-induced oxidative stress causes apoptosis in proximal tubular epithelial cells and is mediated by multiple caspases. FASEB J. 7: 908-910.
3. Andersch, M.A., and Szecypinski, A.J. 1947. Use of p-nitrophenyl phosphate as the substrate for determination of serum acid phosphatase. Am. J. Clin. Pathol. 17: 571-574.
4. Anderson, H.C. 1995. Molecular biology of matrix vesicles. Clin. Orthop. 314: 266-280.
5. Bain, S., Ramamurthy, N.S., Impeduglia, T., Scolman, S., Golub, L.M., and Rubin, C. 1997. Tetracyclin prevents cancellous bone loss and maintains near-normal rates of bone formation in streptozotozin diabetic rats. Bone, 21: 147-153.
6. Balint, E., Szabo, P., Marshall, C.F., and Sprague, S.M. 2001. Glucose-induced inhibition of in vitro bone mineralization. Bone, 28: 21-28.
7. Bellows, C.G., Heersche, J.N., and Aubin, J.E. 1992. Inorganic phosphate added exogenously or released from beta-glycerophosphate initiates mineralization of osteoid nodules in vitro. Bone Miner. 17: 15-29.
8. Boskey, A.L. 1998. Biomineralization: conflicts, challenges, and opportunities. J. Cell. Biochem. Suppl. 30-31: 83-91.
9. Campbell, S.E., and Febbraio, M.A. 2002. Effect of the ovarian hormones on GLUT4 expression and contraction-stimulated glucose uptake. Am. J. Physiol. Endocrinol. Metab. 282: E1139-E1146.
10. Chung, C.H., Golub, E.E., Forbes, E., Tokuoka, T., and Shapiro, I.M. 1992. Mechanism of action of beta-glycerophosphate on bone cell mineralization. Calcif. Tissue Int. 51: 305-311.
11. Conn, H.J., Darrow, M.A., and Emmel, V.M. 1965. Staining procedures used by the biological stain commission. 2nd ed. The Williams and Wilkinson Company., Baltimore, Md. pp. 50-51
12. Czech, M.P., Clancy, B.M., Pessino, A., Woon, C.W., and Harrison, S.A. 1992. Complex regulation of simple sugar transport in insulin-responsive cells. Trends Biochem. Sci. 17: 197-201.
13. De Luise, M.A., and Harker, M. 1988. Insulin stimulation of Na+-K+ pump in clonal rat osteosarcoma cells. Diabetes, 37: 33-37.
14. Digirolamo, C.M., Stokes, D., Colter, D., Phinney, D.G., Class, R., and Prockop, D.J. 1999. Propagation and senescence of human marrow stromal cells in culture: a simple colony-forming assay identifies samples with the greatest potential to propagate and differentiate. Br. J. Haematol. 107: 275-281.
15. Ernst, M., Heath, J.K., and Rodan, G.A. 1989. Estradiol effects on proliferation, messenger ribonucleic acid for collagen and insulin-like growth factor-I, and parathyroid hormone-stimulated adenylate cyclase activity in osteoblastic cells from calvariae and long bones. Endocrinology, 125: 825-833.
16. Garvey, W., Huecksteadt, T., Matthaei, S., and Olefsky. 1988. Role of glucose transporters in the cellular insulin resistance of type-II non-insulin-dependent diabetes mellitus. J. Clin. Investig. 81: 1528-1536.
17. Glimcher, M.J. 1989. Mechanism of calcification: role of collagen fibrils and collagen-phosphoprotein complexes in vitro and in vivo. Anat. Rec. 224: 139-153.
18. Gonzalez, C., Alonso, A., Grueso, N.A., Diaz, F., Esteban, M.M., Fernandez, S., and Patterson, A.M. 2002. Role of 17-beta-estradiol administration on insulin sensitivity in the rat: implications for the insulin receptor. Steroids, 67: 993-1005.
19. Hehenberger, K., Hansson, A., Heilborn, J.D., Abdel-Halim, S.M., Ostensson, C.G., and Brismar, K. 1999. Impaired proliferation and increased L-lactate production of dermal fibroblasts in the GK-rat, a spontaneous model of non-insulin dependent diabetes mellitus. Wound Repair Regen. 7: 65-71.
20. Hickman, J., and McElduff, A. 1988. Insulin promotes growth of cultured rat osteosarcoma cell line UMR-106-01: an osteoblast-like cell. Endocrinology, 124: 701-706.
21. Ikegami, A., Inoue, S., Hosoi, T., Kaneki, M., Mizuno, Y., Akedo, Y., Ouchi, Y., and Orimo, H. 1994. Cell cycle-dependent expression of estrogen receptor and effect of estrogen on proliferation of synchronized human osteoblast-like osteosarcoma cells. Endocrinology, 135: 782-789.
22. Inaba, M., Terada, M., Koyama, H., Yoshida, O., Ishimura, E., and Kawakishi, T. 1995. Influence of high glucose on 1,25-dihydroxyvitamin D3-induced effect of human osteoblasts-like MG-63 cells. J. Bone Miner. Res. 10: 1050-1056.
23. Ituarte, E.A., Ituarte, H.G., Iida-Klein, A., and Hahn, T.H. 1989. Characterization of insulin binding in the UMR-106 rat osteoblastic osteosarcoma cell. J. Bone Miner. Res. 4: 69-73.
24. Kang, B.P., Frencher, S., Reddy, V., Kessler, A., Malhotra, A., and Meggs, L.G. 2003. High glucose promotes mesangial cell apoptosis by oxidant-dependent mechanism. Am. J. Physiol. Renal. Physiol. 284: F455-F466.
25. Katayama, Y., Akatsu, T., Yamamoto, M., Kugai, N., and Nagata, N. 1996. Role of nonenzymatic glycosylation of type-1 collagen in diabetic osteopenia. J. Bone Miner. Res. 11: 931-937.
26. Kihara, T., Oshima, A., Hirose, M., and Ohgushi, H. 2004. Three-dimensional visualization analysis of in vitro cultured bone fabricated by rat marrow mesenchymal stem cells. Biochem. Biophys. Res. Commun. 316: 943-948.
27. Lee, A.V., Jackson, J.J.G., Gooch, J.L., Hilsenbeck, S.G., Coronado-Heinsohn, E., Osborne, C.J., and Yee, D. 1999. Enhancement of insulin-like growth factor signaling in human breast cancer: estrogen regulation of insulin receptor substrate-1 expression in vitro and in vivo. Mol. Endocrinol. 13: 787-796.
28. Levy, J.R., Murray, E., Manolagas, S., and Olefsky, J.M. 1986. Demonstration of insulin receptors and modulation of alkaline phosphatase activity by insulin in rat osteoblastic cells. Endocrinology, 119: 1786-1792.
29. Lian, J.B., and Stein, G.S. 1992. Transcriptional control of vitamin D-regulated proteins. J. Cell. Biochem. 49: 37-45.
30. Lian, J.B., and Stein, G.S. 1995. Development of the osteoblast phenotype: molecular mechanisms mediating osteoblast growth and differentiation. Iowa Orthop. J. 15: 118-140.
31. Lien, Y.H., Stern, R., Fu, C.C.C., and Siegel, R.C. 1984. Inhibition of collagen fibril formation in vitro and subsequent cross-linking by glucose. Science (Washington, D.C.), 255: 1489-1491.
32. Linde, A., and Goldberg, M. 1993. Dentinogenesis. Crit. Rev. Oral Biol. Med. 4: 679-728.
33. Lowry, O.H., Rosebrough, N.J., Far, A.B., and Randall, R.J. 1951. Protein measurements with follin-phenol reagent. J. Biol. Chem. 193: 265-275
34. Majeska, R.J., Ryaby, J.T., and Einhorn, T.A. 1994. Direct modulation of osteoblastic activity with estrogen. J. Bone Jt. Surg. Am. 76: 713-721.
35. Maor, G., and Karnieli, E. 1999. The insulin-sensitive glucose transporter (GLUT4) is involved in early bone growth in control and diabetic mice, but is regulated through the insulin-like growth factor I receptor. Endocrinology, 140: 1841-1851.
36. Marsden, P.J., Murdoch, A., and Taylor, R. 1996. Adipocyte insulin action during the normal menstrual cycle. Hum. Reprod. 11: 968-974.
37. Milne, M., Kang, M.I., Cardona, G., Quail, J.M., Braverman, L.E., Chin, W.W., and Baran, D.T. 1999. Expression of multiple thyroid hormone receptor isoforms in rat femoral and vertebral bone and in bone marrow osteogenic cultures. J. Cell. Biochem. 74: 684-693.
38. Mishra, R., Emancipator, S.N., Kern, T., and Simonson, M.S. 2005. High glucose evokes an intrinsic proapoptotic signaling pathway in mesangial cells. Kidney Int. 67: 82-93.
39. Molloy, C.A., May, F.E., and Westley, B.R. 2000. Insulin receptor substrate-1 expression is regulated by estrogen in the MCF-7 human breast cancer cell line. J. Biol. Chem. 275: 12565-12571.
40. Morohoshi, M., Fujisawa, K., Uchimura, I., and Numano, F. 1996. Glucose dependent interleukin 6 and tumor necrosis factor production by human peripheral blood monocytes in vitro. Diabetes, 45: 954-959.
41. Mueckler, M. 1994. Facilitative glucose transporters. Eur. J. Biochem. 219: 713-725.
42. O'Shaughnessy, M.C., Polak, J.M., Afzal, F., Hukkanen, M.V.J., Huang, P., MacIntyre, I., and Buttery, L.D.K. 2000. Nitric oxide mediates 17-b estradiol stimulated human and rodent osteoblast differentiation and proliferation. Biochem. Biophys. Res. Commun. 277: 604-610.
43. Ogata, N., Chikazu, D., Kubota, N., Terauchi, Y., Tobe, K., Azuma, Y. et al. 2000. Insulin receptor substrate-1 in osteoblast is indispensable for maintaining bone turnover. J. Clin. Investig. 105: 935-943.
44. Pittenger, M.F., Mackay, K.W., and Beck, S.C. 1999. Multilineage potential of adult human mesenchymal stem cells. Science (Washington, D.C.), 284: 143-147.
45. Polderman, K.H., Gooren, L.J.G., Asschman, H., Bakker, A., and Heine, R.J. 1994. Induction of insulin resistance by androgens and estrogens. J. Clin. Endocrinol. Metab. 79: 265-271.
46. Pun, K.K., Lau, P., and Ho, P.W.M. 1989. The characterization, regulation and function of insulin receptors on osteoblast-like clonal osteosarcoma cell-line. J. Bone Miner. Res. 4: 853-862.
47. Qu, Q., Perala-Heape, M., Kapanen, A., Dahllund, J., Salo, J., Vaananen, H.K., and Harkonen, P. 1998. Estrogen enhances differentiation of osteoblasts in mouse bone marrow culture. Bone, 22: 201-209.
48. Rickard, D.J., Kazhdan, I., and Leboy, P.S. 1995. Importance of 1,25-dihydroxyvitamin D3 and the nonadherent cells of marrow for osteoblast differentiation from rat marrow stromal cells. Bone, 16: 671-678.
49. Scheven, B.A., Damen, C.A., Hamilton, N.J., Verhaar, H.J., and Duursma, S.A. 1992. Stimulatory effects of estrogen and progesterone on proliferation and differentiation of normal human osteoblast-like cells in vitro. Biochem. Biophys. Res. Commun. 186: 54-60.
50. Sekiguchi, N., Inoguchi, T., Kobayashi, K., and Nawata, H. 2004. Effect of erythropoietin on endothelial cell apoptosis induced by high glucose. Diabetes Res. Clin. Pract. 66(Suppl. 1): S103-S107.
51. Siddhanti, S.R., and Quarles, L.D. 1994. Molecular to pharmacologic control of osteoblast proliferation and differentiation. J. Cell. Biochem. 55: 310-320.
52. Solini, A., Chiozzi, P., Falzoni, S., Morelli, A., Fellin, R., and Virgilio, F. 2000. High glucose modulates P2Z7 receptor-mediated function in human primary fibroblasts. Diabetologia, 43: 1248-1256.
53. Sun, X.J., Miralpeix, M., Meyrs, M.G., Glasheen, E.M., Backer, J.M., Kahn, C.R., and White, M.F. 1992. Expression and function of IRS-1 in insulin signal transmisstion. J. Biol. Chem. 267: 22662-22672.
54. Terada, M., Inaba, M., Yano, Y., Hasuma, T., Nishizawa, Y., Morii, H., and Otani, S. 1998. Growth-inhibitory effect of a high glucose concentration on osteoblast-like cells. Bone, 22: 17-23.
55. Thomas, D.M., Hards, D.K., Rogers, S.D., Ng, K.W., and Best, J.D. 1996. Insulin receptor expression in bone. J. Bone Miner. Res. 11: 1312-1320.
56. Verhofstad, M.H., Bisseling, T.M., Haans, E.M., and Henriks, T. 1998. Collagen synthesis in rat skin and ileum fibroblasts is affected differently by diabetes-related factors. Int. J. Exp. Pathol. 79: 321-328.
57. Williams, J.P., Blair, H.C., McDonald, J.M., McKenna, M.A., Jordan, S.E., Williford, J., and Hardy, R.W. 1997. Regulation of osteoclastic bone resorption by glucose. Biochem. Biophys. Res. Commun. 253: 646-651.
58. kip1, an inhibitor of cyclin-dependent kinase. Am. J. Pathol. 158: 1091-1100.