-
1
-
-
0032535483
-
The ubiquitin-proteasome pathway: On protein death and cell life
-
Ciechanover A (1998) The ubiquitin-proteasome pathway: on protein death and cell life. Embo J 17: 7151-7160.
-
(1998)
Embo J
, vol.17
, pp. 7151-7160
-
-
Ciechanover, A.1
-
2
-
-
23144449208
-
Ubiquitin and ubiquitin-like proteins as multifunctional signals
-
Welchman RL, Gordon C, Mayer RJ (2005) Ubiquitin and ubiquitin-like proteins as multifunctional signals. Nat Rev Mol Cell Biol 6: 599-609.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 599-609
-
-
Welchman, R.L.1
Gordon, C.2
Mayer, R.J.3
-
3
-
-
0036227219
-
The challenges of developing a sound proteomics strategy
-
Hancock WS, Wu SL, Shieh P (2002) The challenges of developing a sound proteomics strategy. Proteomics 2: 352-359.
-
(2002)
Proteomics
, vol.2
, pp. 352-359
-
-
Hancock, W.S.1
Wu, S.L.2
Shieh, P.3
-
4
-
-
26944464255
-
Prospects and challenges in proteomics
-
Bertone P, Snyder M (2005) Prospects and challenges in proteomics. Plant Physiol 138: 560-562.
-
(2005)
Plant Physiol
, vol.138
, pp. 560-562
-
-
Bertone, P.1
Snyder, M.2
-
5
-
-
0036198435
-
Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae
-
Ficarro SB, McCleland ML, Stukenberg PT, Burke DJ, Ross MM, et al. (2002) Phosphoproteome analysis by mass spectrometry and its application to Saccharomyces cerevisiae. Nat Biotechnol 20: 301-305.
-
(2002)
Nat Biotechnol
, vol.20
, pp. 301-305
-
-
Ficarro, S.B.1
McCleland, M.L.2
Stukenberg, P.T.3
Burke, D.J.4
Ross, M.M.5
-
6
-
-
28444460297
-
Global analysis of protein phosphorylation in yeast
-
Ptacek J, Devgan G, Michaud G, Zhu H, Zhu X, et al. (2005) Global analysis of protein phosphorylation in yeast. Nature 438: 679-684.
-
(2005)
Nature
, vol.438
, pp. 679-684
-
-
Ptacek, J.1
Devgan, G.2
Michaud, G.3
Zhu, H.4
Zhu, X.5
-
7
-
-
34249947558
-
Ubiquitination screen using protein microarrays for comprehensive identification of Rsp5 substrates in yeast
-
Gupta R, Kus B, Fladd C, Wasmuth J, Tonikian R, et al. (2007) Ubiquitination screen using protein microarrays for comprehensive identification of Rsp5 substrates in yeast. Mol Syst Biol 3: 116.
-
(2007)
Mol Syst Biol
, vol.3
, pp. 116
-
-
Gupta, R.1
Kus, B.2
Fladd, C.3
Wasmuth, J.4
Tonikian, R.5
-
8
-
-
62449196769
-
Large-scale detection of ubiquitination substrates using cell extracts and protein microarrays
-
Merbl Y, Kirschner MW (2009) Large-scale detection of ubiquitination substrates using cell extracts and protein microarrays. Proc Natl Acad Sci U S A 106: 2543-2548.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 2543-2548
-
-
Merbl, Y.1
Kirschner, M.W.2
-
9
-
-
0035942224
-
Skp2 is oncogenic and overexpressed in human cancers
-
Gstaiger M, Jordan R, Lim M, Catzavelos C, Mestan J, et al. (2001) Skp2 is oncogenic and overexpressed in human cancers. Proc Natl Acad Sci U S A 98: 5043-5048.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 5043-5048
-
-
Gstaiger, M.1
Jordan, R.2
Lim, M.3
Catzavelos, C.4
Mestan, J.5
-
10
-
-
0035092687
-
The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27
-
Ganoth D, Bornstein G, Ko TK, Larsen B, Tyers M, et al. (2001) The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27. Nat Cell Biol 3: 321-324.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 321-324
-
-
Ganoth, D.1
Bornstein, G.2
Ko, T.K.3
Larsen, B.4
Tyers, M.5
-
11
-
-
0035265829
-
A CDK-independent function of mammalian Cks1: Targeting of SCF(Skp2) to the CDK inhibitor p27Kip1
-
Spruck C, Strohmaier H, Watson M, Smith AP, Ryan A, et al. (2001) A CDK-independent function of mammalian Cks1: targeting of SCF(Skp2) to the CDK inhibitor p27Kip1. Mol Cell 7: 639-650.
-
(2001)
Mol Cell
, vol.7
, pp. 639-650
-
-
Spruck, C.1
Strohmaier, H.2
Watson, M.3
Smith, A.P.4
Ryan, A.5
-
12
-
-
33750982397
-
Livin promotes Smac/DIABLO degradation by ubiquitin-proteasome pathway
-
Ma L, Huang Y, Song Z, Feng S, Tian X, et al. (2006) Livin promotes Smac/DIABLO degradation by ubiquitin-proteasome pathway. Cell Death Differ 13: 2079-2088.
-
(2006)
Cell Death Differ
, vol.13
, pp. 2079-2088
-
-
Ma, L.1
Huang, Y.2
Song, Z.3
Feng, S.4
Tian, X.5
-
13
-
-
34648816891
-
Conserved function of RNF4 family proteins in eukaryotes: Targeting a ubiquitin ligase to SUMOylated proteins
-
Sun H, Leverson JD, Hunter T (2007) Conserved function of RNF4 family proteins in eukaryotes: targeting a ubiquitin ligase to SUMOylated proteins. Embo J 26: 4102-4112.
-
(2007)
Embo J
, vol.26
, pp. 4102-4112
-
-
Sun, H.1
Leverson, J.D.2
Hunter, T.3
-
14
-
-
28544431575
-
A novel RING-type ubiquitin ligase breast cancer-associated gene 2 correlates with outcome in invasive breast cancer
-
Burger AM, Gao Y, Amemiya Y, Kahn HJ, Kitching R, et al. (2005) A novel RING-type ubiquitin ligase breast cancer-associated gene 2 correlates with outcome in invasive breast cancer. Cancer Res 65: 10401-10412.
-
(2005)
Cancer Res
, vol.65
, pp. 10401-10412
-
-
Burger, A.M.1
Gao, Y.2
Amemiya, Y.3
Kahn, H.J.4
Kitching, R.5
-
15
-
-
0345616428
-
A ubiquitin-binding motif required for intramolecular monoubiquitylation, the CUE domain
-
Shih SC, Prag G, Francis SA, Sutanto MA, Hurley JH, et al. (2003) A ubiquitin-binding motif required for intramolecular monoubiquitylation, the CUE domain. Embo J 22: 1273-1281.
-
(2003)
Embo J
, vol.22
, pp. 1273-1281
-
-
Shih, S.C.1
Prag, G.2
Francis, S.A.3
Sutanto, M.A.4
Hurley, J.H.5
-
16
-
-
0037646406
-
Rad23 ubiquitin-associated domains (UBA) inhibit 26 S proteasome-catalyzed proteolysis by sequestering lysine 48-linked polyubiquitin chains
-
Raasi S, Pickart CM (2003) Rad23 ubiquitin-associated domains (UBA) inhibit 26 S proteasome-catalyzed proteolysis by sequestering lysine 48-linked polyubiquitin chains. J Biol Chem 278: 8951-8959.
-
(2003)
J Biol Chem
, vol.278
, pp. 8951-8959
-
-
Raasi, S.1
Pickart, C.M.2
-
17
-
-
4644302353
-
The c-Cbl/CD2AP complex regulates VEGF-induced endocytosis and degradation of Flt-1 (VEGFR-1)
-
Kobayashi S, Sawano A, Nojima Y, Shibuya M, Maru Y (2004) The c-Cbl/CD2AP complex regulates VEGF-induced endocytosis and degradation of Flt-1 (VEGFR-1). Faseb J 18: 929-931.
-
(2004)
Faseb J
, vol.18
, pp. 929-931
-
-
Kobayashi, S.1
Sawano, A.2
Nojima, Y.3
Shibuya, M.4
Maru, Y.5
-
18
-
-
0346101802
-
SHP-2 regulates SOCS-1-mediated Janus kinase-2 ubiquitination/degradation downstream of the prolactin receptor
-
Ali S, Nouhi Z, Chughtai N, Ali S (2003) SHP-2 regulates SOCS-1-mediated Janus kinase-2 ubiquitination/degradation downstream of the prolactin receptor. J Biol Chem 278: 52021-52031.
-
(2003)
J Biol Chem
, vol.278
, pp. 52021-52031
-
-
Ali, S.1
Nouhi, Z.2
Chughtai, N.3
Ali, S.4
-
19
-
-
0034625744
-
The APS adapter protein couples the insulin receptor to the phosphorylation of c-Cbl and facilitates ligand-stimulated ubiquitination of the insulin receptor
-
Ahmed Z, Smith BJ, Pillay TS (2000) The APS adapter protein couples the insulin receptor to the phosphorylation of c-Cbl and facilitates ligand-stimulated ubiquitination of the insulin receptor. FEBS Lett 475: 31-34.
-
(2000)
FEBS Lett
, vol.475
, pp. 31-34
-
-
Ahmed, Z.1
Smith, B.J.2
Pillay, T.S.3
-
20
-
-
63049109748
-
The ubiquitin receptor Rad23: At the crossroads of nucleotide excision repair and proteasomal degradation
-
Dantuma NP, Heinen C, Hoogstraten D (2009) The ubiquitin receptor Rad23: at the crossroads of nucleotide excision repair and proteasomal degradation. DNA Repair (Amst) 8: 449-460.
-
(2009)
DNA Repair (Amst)
, vol.8
, pp. 449-460
-
-
Dantuma, N.P.1
Heinen, C.2
Hoogstraten, D.3
-
21
-
-
0033603339
-
Identification of HHR23A as a substrate for E6-associated protein-mediated ubiquitination
-
Kumar S, Talis AL, Howley PM (1999) Identification of HHR23A as a substrate for E6-associated protein-mediated ubiquitination. J Biol Chem 274: 18785-18792.
-
(1999)
J Biol Chem
, vol.274
, pp. 18785-18792
-
-
Kumar, S.1
Talis, A.L.2
Howley, P.M.3
-
23
-
-
17644377920
-
Covalent modification of human homeodomain interacting protein kinase 2 by SUMO-1 at lysine 25 affects its stability
-
Gresko E, Moller A, Roscic A, Schmitz ML (2005) Covalent modification of human homeodomain interacting protein kinase 2 by SUMO-1 at lysine 25 affects its stability. Biochem Biophys Res Commun 329: 1293-1299.
-
(2005)
Biochem Biophys Res Commun
, vol.329
, pp. 1293-1299
-
-
Gresko, E.1
Moller, A.2
Roscic, A.3
Schmitz, M.L.4
-
24
-
-
0035918226
-
SUMO-1 conjugation in vivo requires both a consensus modification motif and nuclear targeting
-
Rodriguez MS, Dargemont C, Hay RT (2001) SUMO-1 conjugation in vivo requires both a consensus modification motif and nuclear targeting. J Biol Chem 276: 12654-12659.
-
(2001)
J Biol Chem
, vol.276
, pp. 12654-12659
-
-
Rodriguez, M.S.1
Dargemont, C.2
Hay, R.T.3
-
25
-
-
33747795350
-
A general approach for investigating enzymatic pathways and substrates for ubiquitin-like modifiers
-
Li T, Santockyte R, Shen RF, Tekle E, Wang G, et al. (2006) A general approach for investigating enzymatic pathways and substrates for ubiquitin-like modifiers. Arch Biochem Biophys 453: 70-74.
-
(2006)
Arch Biochem Biophys
, vol.453
, pp. 70-74
-
-
Li, T.1
Santockyte, R.2
Shen, R.F.3
Tekle, E.4
Wang, G.5
-
26
-
-
33644701400
-
Analysis of Nedd8-associated polypeptides: A model for deciphering the pathway for ubiquitin-like modifications
-
Norman JA, Shiekhattar R (2006) Analysis of Nedd8-associated polypeptides: a model for deciphering the pathway for ubiquitin-like modifications. Biochemistry 45: 3014-3019.
-
(2006)
Biochemistry
, vol.45
, pp. 3014-3019
-
-
Norman, J.A.1
Shiekhattar, R.2
-
27
-
-
44449129585
-
A targeted proteomic analysis of the ubiquitin-like modifier nedd8 and associated proteins
-
Jones J, Wu K, Yang Y, Guerrero C, Nillegoda N, et al. (2008) A targeted proteomic analysis of the ubiquitin-like modifier nedd8 and associated proteins. J Proteome Res 7: 1274-1287.
-
(2008)
J Proteome Res
, vol.7
, pp. 1274-1287
-
-
Jones, J.1
Wu, K.2
Yang, Y.3
Guerrero, C.4
Nillegoda, N.5
-
28
-
-
1842591241
-
Nedd8 on cullin: Building an expressway to protein destruction
-
Pan ZQ, Kentsis A, Dias DC, Yamoah K, Wu K (2004) Nedd8 on cullin: building an expressway to protein destruction. Oncogene 23: 1985-1997.
-
(2004)
Oncogene
, vol.23
, pp. 1985-1997
-
-
Pan, Z.Q.1
Kentsis, A.2
Dias, D.C.3
Yamoah, K.4
Wu, K.5
-
29
-
-
0036742399
-
Role of the Arabidopsis RING-H2 protein RBX1 in RUB modification and SCF function
-
Gray WM, Hellmann H, Dharmasiri S, Estelle M (2002) Role of the Arabidopsis RING-H2 protein RBX1 in RUB modification and SCF function. Plant Cell 14: 2137-2144.
-
(2002)
Plant Cell
, vol.14
, pp. 2137-2144
-
-
Gray, W.M.1
Hellmann, H.2
Dharmasiri, S.3
Estelle, M.4
-
30
-
-
0032727343
-
The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2
-
Kamura T, Conrad MN, Yan Q, Conaway RC, Conaway JW (1999) The Rbx1 subunit of SCF and VHL E3 ubiquitin ligase activates Rub1 modification of cullins Cdc53 and Cul2. Genes Dev 13: 2928-2933.
-
(1999)
Genes Dev
, vol.13
, pp. 2928-2933
-
-
Kamura, T.1
Conrad, M.N.2
Yan, Q.3
Conaway, R.C.4
Conaway, J.W.5
-
31
-
-
0037423760
-
Nedd8-modification of Cul1 is promoted by Roc1 as a Nedd8-E3 ligase and regulates its stability
-
Morimoto M, Nishida T, Nagayama Y, Yasuda H (2003) Nedd8-modification of Cul1 is promoted by Roc1 as a Nedd8-E3 ligase and regulates its stability. Biochem Biophys Res Commun 301: 392-398.
-
(2003)
Biochem Biophys Res Commun
, vol.301
, pp. 392-398
-
-
Morimoto, M.1
Nishida, T.2
Nagayama, Y.3
Yasuda, H.4
-
32
-
-
21744455599
-
The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae
-
Kurz T, Ozlu N, Rudolf F, O'Rourke SM, Luke B, et al. (2005) The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae. Nature 435: 1257-1261.
-
(2005)
Nature
, vol.435
, pp. 1257-1261
-
-
Kurz, T.1
Ozlu, N.2
Rudolf, F.3
O'Rourke, S.M.4
Luke, B.5
-
33
-
-
0035906430
-
Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome
-
Lyapina S, Cope G, Shevchenko A, Serino G, Tsuge T, et al. (2001) Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome. Science 292: 1382-1385.
-
(2001)
Science
, vol.292
, pp. 1382-1385
-
-
Lyapina, S.1
Cope, G.2
Shevchenko, A.3
Serino, G.4
Tsuge, T.5
-
34
-
-
36949032298
-
SRC family nonreceptor tyrosine kinases as molecular targets for cancer therapy
-
Johnson FM, Gallick GE (2007) SRC family nonreceptor tyrosine kinases as molecular targets for cancer therapy. Anticancer Agents Med Chem 7: 651-659.
-
(2007)
Anticancer Agents Med Chem
, vol.7
, pp. 651-659
-
-
Johnson, F.M.1
Gallick, G.E.2
-
35
-
-
28844468834
-
Experimental tests to definitively determine ubiquitylation of a substrate
-
Bloom J, Pagano M (2005) Experimental tests to definitively determine ubiquitylation of a substrate. Methods Enzymol 399: 249-266.
-
(2005)
Methods Enzymol
, vol.399
, pp. 249-266
-
-
Bloom, J.1
Pagano, M.2
-
37
-
-
3242879529
-
Evidence and credibility: Full Bayesian significance test for precise hypotheses
-
Pereira CA, Stern JM (1999) Evidence and credibility: Full Bayesian significance test for precise hypotheses. Entropy 1: 99-110.
-
(1999)
Entropy
, vol.1
, pp. 99-110
-
-
Pereira, C.A.1
Stern, J.M.2
-
38
-
-
2942702012
-
Yin Yang 1 is a negative regulator of p53
-
Sui G, Affar el B, Shi Y, Brignone C, Wall NR, et al. (2004) Yin Yang 1 is a negative regulator of p53. Cell 117: 859-872.
-
(2004)
Cell
, vol.117
, pp. 859-872
-
-
Sui, G.1
Affar el, B.2
Shi, Y.3
Brignone, C.4
Wall, N.R.5
-
39
-
-
33645120412
-
X linked mental retardation: A clinical guide
-
Raymond FL (2006) X linked mental retardation: a clinical guide. J Med Genet 43: 193-200.
-
(2006)
J Med Genet
, vol.43
, pp. 193-200
-
-
Raymond, F.L.1
-
40
-
-
34250769508
-
Regulation of synaptic growth and maturation by a synapse-associated E3 ubiquitin ligase at the neuromuscular junction
-
Lu Z, Je HS, Young P, Gross J, Lu B, et al. (2007) Regulation of synaptic growth and maturation by a synapse-associated E3 ubiquitin ligase at the neuromuscular junction. J Cell Biol 177: 1077-1089.
-
(2007)
J Cell Biol
, vol.177
, pp. 1077-1089
-
-
Lu, Z.1
Je, H.S.2
Young, P.3
Gross, J.4
Lu, B.5
-
41
-
-
14244260623
-
Defining the SUMO-modified proteome by multiple approaches in Saccharomyces cerevisiae
-
Hannich JT, Lewis A, Kroetz MB, Li SJ, Heide H, et al. (2005) Defining the SUMO-modified proteome by multiple approaches in Saccharomyces cerevisiae. J Biol Chem 280: 4102-4110.
-
(2005)
J Biol Chem
, vol.280
, pp. 4102-4110
-
-
Hannich, J.T.1
Lewis, A.2
Kroetz, M.B.3
Li, S.J.4
Heide, H.5
-
42
-
-
34247528121
-
A proteomics approach to identify the ubiquitinated proteins in mouse heart
-
Jeon HB, Choi ES, Yoon JH, Hwang JH, Chang JW, et al. (2007) A proteomics approach to identify the ubiquitinated proteins in mouse heart. Biochem Biophys Res Commun 357: 731-736.
-
(2007)
Biochem Biophys Res Commun
, vol.357
, pp. 731-736
-
-
Jeon, H.B.1
Choi, E.S.2
Yoon, J.H.3
Hwang, J.H.4
Chang, J.W.5
-
43
-
-
33745360876
-
Automated identification of SUMOylation sites using mass spectrometry and SUMmOn pattern recognition software
-
Pedrioli PG, Raught B, Zhang XD, Rogers R, Aitchison J, et al. (2006) Automated identification of SUMOylation sites using mass spectrometry and SUMmOn pattern recognition software. Nat Methods 3: 533-539.
-
(2006)
Nat Methods
, vol.3
, pp. 533-539
-
-
Pedrioli, P.G.1
Raught, B.2
Zhang, X.D.3
Rogers, R.4
Aitchison, J.5
-
44
-
-
0034654399
-
The KEN box: An APC recognition signal distinct from the D box targeted by Cdh1
-
Pfleger CM, Kirschner MW (2000) The KEN box: an APC recognition signal distinct from the D box targeted by Cdh1. Genes Dev 14: 655-665.
-
(2000)
Genes Dev
, vol.14
, pp. 655-665
-
-
Pfleger, C.M.1
Kirschner, M.W.2
-
45
-
-
0028108747
-
Evidence for N-glycosylation and ubiquitination of the prolactin receptor expressed in a baculovirus-insect cell system
-
Cahoreau C, Garnier L, Djiane J, Devauchelle G, Cerutti M (1994) Evidence for N-glycosylation and ubiquitination of the prolactin receptor expressed in a baculovirus-insect cell system. FEBS Lett 350: 230-234.
-
(1994)
FEBS Lett
, vol.350
, pp. 230-234
-
-
Cahoreau, C.1
Garnier, L.2
Djiane, J.3
Devauchelle, G.4
Cerutti, M.5
-
47
-
-
72449163470
-
The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress
-
Morris JR, Boutell C, Keppler M, Densham R, Weekes D, et al. (2009) The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress. Nature 462: 886-890.
-
(2009)
Nature
, vol.462
, pp. 886-890
-
-
Morris, J.R.1
Boutell, C.2
Keppler, M.3
Densham, R.4
Weekes, D.5
-
48
-
-
72449175818
-
Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks
-
Galanty Y, Belotserkovskaya R, Coates J, Polo S, Miller KM, et al. (2009) Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks. Nature 462: 935-939.
-
(2009)
Nature
, vol.462
, pp. 935-939
-
-
Galanty, Y.1
Belotserkovskaya, R.2
Coates, J.3
Polo, S.4
Miller, K.M.5
-
49
-
-
73649083381
-
SUMO boosts the DNA damage response barrier against cancer
-
Bartek J, Hodny Z (2010) SUMO boosts the DNA damage response barrier against cancer. Cancer Cell 17: 9-11.
-
(2010)
Cancer Cell
, vol.17
, pp. 9-11
-
-
Bartek, J.1
Hodny, Z.2
-
50
-
-
77951622671
-
A20: From ubiquitin editing to tumour suppression
-
Hymowitz SG, Wertz IE (2010) A20: from ubiquitin editing to tumour suppression. Nat Rev Cancer 10: 332-341.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 332-341
-
-
Hymowitz, S.G.1
Wertz, I.E.2
-
51
-
-
0029918062
-
Crystal structure and mutational analysis of the human CDK2 kinase complex with cell cycle-regulatory protein CksHs1
-
Bourne Y, Watson MH, Hickey MJ, Holmes W, Rocque W, et al. (1996) Crystal structure and mutational analysis of the human CDK2 kinase complex with cell cycle-regulatory protein CksHs1. Cell 84: 863-874.
-
(1996)
Cell
, vol.84
, pp. 863-874
-
-
Bourne, Y.1
Watson, M.H.2
Hickey, M.J.3
Holmes, W.4
Rocque, W.5
|