AhR-agonistic, anti-androgenic, and anti-estrogenic potencies of 2-isopropylthioxanthone (ITX) as determined by in vitro bioassays and gene expression profiling

Toxicology in Vitro

Volumn 24, Issue 6, 2010, Pages 1619-1628

  Peijnenburg, Ad ^a   Riethof Poortman, Jenneke ^a   Baykus, Hakan ^a   Portier, Liza ^a   Bovee, Toine ^a   Hoogenboom, Ron ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

2,3,7,8 Tetrachlorodibenzo p dioxin; DNA microarrays; DR CALUX ; EROD; Isopropylthioxanthone; Photoinitiator; Yeast hormone bioassays

Indexed keywords

2 ISOPROPYLTHIOXANTHENE; 2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ANDROGEN; AROMATIC HYDROCARBON RECEPTOR; ESTROGEN; ETHOXYRESORUFIN DEETHYLASE; FUROCOUMARIN DERIVATIVE; THIOXANTHENE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BIOASSAY; CONTROLLED STUDY; DNA MICROARRAY; GENE EXPRESSION PROFILING; HAZARD ASSESSMENT; HEPATOMA CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; RAT;

ANDROGEN ANTAGONISTS; ANIMALS; BIOSENSING TECHNIQUES; CELL LINE, TUMOR; CELL SURVIVAL; CYTOCHROME P-450 CYP1A1; ENDOCRINE DISRUPTORS; ESTROGEN RECEPTOR MODULATORS; GENE EXPRESSION; GENE EXPRESSION PROFILING; HEPATOCYTES; HORMONE ANTAGONISTS; LUCIFERASES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RATS; RECEPTORS, ARYL HYDROCARBON; RNA, MESSENGER; SACCHAROMYCES CEREVISIAE; THIOXANTHENES;

RATTUS;

EID: 77956177711     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2010.06.004     Document Type: Article

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