Validation and use of the CALUX‐bioassay for the determination of dioxins and PCBs in bovine milk

Food Additives and Contaminants

Volumn 15, Issue 8, 1998, Pages 863-875

  Bovee, Toine F H ^a   Hoogenboom, Laurentius A P ^a   Hamers, Astrid R M ^a   Traag, Wim A ^a   Zuidema, Tina ^a   Aarts, Jac M M J G ^a   Brouwer, Abraham ^a   Kuiper, Harry A ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Bioassay; CALUX; Dioxins; Milk; PCBs; Polyhalogenated aromatic hydrocarbons; Validation

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; DIOXIN; MILK FAT; POLYCHLORINATED BIPHENYL;

ARTICLE; BIOASSAY; BUTTER; CATTLE; FOOD ANALYSIS; FOOD CONTAMINATION; NONHUMAN; PRIORITY JOURNAL;

BOS TAURUS; BOVINAE; ERAGROSTIS TEF; MAMMALIA;

EID: 0031744087     PISSN: 0265203X     EISSN: 14645122     Source Type: Journal    
DOI: 10.1080/02652039809374723     Document Type: Article

References (35)

1. Aarts, J. M. M. J. G., Denison, M. S., Cox, M. A., Schalk, A. C., Garrison, P. A., Tullis, K., Haan, L. H. J. de, and Brouwer, A., 1995, Species-specific antagonism of Ah receptor action by 2,2', 5,5'-tetrachloro- and 2,2',3,3',4,4'-hexachlor-obiphenyl. European Journal of Pharmacology and Environmental Toxicology, 293, 463-474.
2. Aarts, J. M. M. J. G., Cenijn, P. H., Blankvoort, B. M. G., Murk, A. J., Bovee, T. F. H., Traag, W. A., Hoogenboom, L. A. P., Patandin, S., Weisglas-Kuperus, N., Sauer, P. J. J., Denison, M. S., and Brouwer, A., 1996, Application of the chemical-activated luciferase expression (CALUX) bioassay for quantification of dioxin-like compounds in small samples of human milk and blood plasma. Organohalogen Compounds, 27, 285-290.
3. Abbott, B. D., Perdew, G. H., Buckalew, A. R., and Birnbaum, L. S., 1994, Interactive regulation of Ah and glucocorticoid receptors in the synergistic induction of cleft palate by 2,3,7,8-tetrachloro-p-dioxin and hydrocortisone. Toxicology and Applied Pharmacology, 128, 138-150.
4. Ahlborg, U. G., Brouwer, A., Fingerhut, M. A., Jacobsen, J. L., Jacobsen, S. W., Kennedy, S. W., Kettrup, A. A. F., Koeman, J. H., Poiger, H., Rappe, C., Safe, S. H., Seegal, R. F., Tuomistro, J., and van den Berg, M., 1992, Impact of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls on human and environmental health, with special emphasis on application of the toxic equivalency factor concept. European Journal of Pharmacology and Environmental Toxicology, 228, 179-199.
5. Ahlborg, U. G., Becking, G. C., Birnbaum, L. S., Brouwer, A., Derks, H. J. G. M., Feeley, M., Golor, G., Hanberg, A., Larsen, J. C., Liem, A. K. M., Safe, S. H., Schlatter, C., Wern, F., Younes, M., and Yrjanheikki, E., 1994, Toxic Equivalency Factors for dioxin-like PCBs. Chemosphere, 28, 1049-1067.
6. Bovee, T. F. H., Hoogenboom, L. A. P., Traag, W. A., Zuidema, T., Horstman, J. H. J., Aarts, J. M. M. J. G., Murk, T. J., Brouwer, A., Denison, M. S., and Kuiper, H. A., 1996, Biological screening of Ah receptor agonist activity in butter fat and coconut oil by means of chemical-activated luciferase expression in a genetically engineered cell line (CALUX). Organohalogen Compounds, 27, 303-308.
7. Brouwer, A., 1991, The role of enzymes in regulating the toxicity of xenobiotics. Role of biotransformation in PCB-induced alterations in vitamin A and thyroid hormone metabolism in laboratory and wildlife species. Biochemical Society Transactions, 19, 731-738.
8. Denison, M. S., and Whitlock, J. P., 1995, Xenobiotic-inducible transcription of cytochrome P450 genes. Journal of Biological Chemistry, 270, 18175-18178.
9. Denison, M. S., and Yao, E. F., 1991, Characterization of the interaction of transformed rat hepatic cytosolic Ah receptor with a dioxin responsive transcriptional enhancer. Archives of Biochemistry and Biophysics, 284, 158-166.
10. Devaux, A., Pesonen, M., Monod, G., and Andersson, T., 1992, Glucocorticoid-mediated potentiation of P450 induction in primary culture of rainbow trout hepatocytes. Biochemical Pharmacology, 43, 898-901.
11. De Vito, M. J., and Birnbaum, L. S., 1994, Toxicology of dioxins and related chemicals. In Dioxins and Health, edited by A. Schecter (New York: Plenum), pp. 139-162.
12. Donato, M. T., Gomez-Lechon, M. J., and Castell, J. V., 1990, Effects of xenobiotics on monooxygenase activities in cultured human hepatocytes. Biochemical Pharmacology, 39, 1321-1326.
13. Eggens, M., Bergman, A., Vethaak, D., Weiden, M. v.d., Celander, M., and Boon, J. P., 1995, Cytochrome P4501A indices as biomarkers of contaminant exposure: results of a field study with plaice (Pleuronectes platessa) and flounder (Pla-tichthys flesus) from the southern North Sea. Aquatic Toxicology, 32,211-225.
14. Garrison, P. A., Tullis, K., Aarts, J. M. M. J. G., Brouwer, A., Giesy, J. P., and Denison, M. S., 1996, Stress-specific recombinant cell lines as bioassay systems for the detection of 2,3,7,8-tetrachlorodibenzo-p-dioxine-like chemicals. Fundamental and Applied Toxicology, 30, 194-203.
15. Giesy, J. P., Ludwig, J. P., and Tillit, D. E., 1994, Embryolethality and deformities in colonial, fish-eating, water birds of the Great Lakes regions: assessing causality. Environmental Science and Technology, 28, 128A-135A.
16. Hoogenboom, L. A. P., and Hamers, A. R. M., 1995, Effects of oxfendazole on the Ah receptor-mediated induction of ethox-yresorufin-O-deethylase and luciferase activity by 2,3,7,8-tetra-chlorodibenzo-p-dioxin in Hepa-lclc7 and H4IIE cell-lines. Organohalogen Compounds, 25, 53-56.
17. Jones, P. D., Ankley, G. T., Best, D. A., Crawford, R., DeGalan, N., Giesy, J. P., Kubiak, T. J., Ludwig, J. P., Newsted, J. L., Tillitt, D. E., and Verbrugge, D. A., 1993, Biomagnification of bioassay derived 2,3,7,8-tetrachlor-odibenzo-p-dioxin equivalents. Chemosphere, 26, 1203-1212.
18. Kennedy, S. W., Lorenzen, A., James, C. A., and Collins, B. T., 1993, Ethoxyresorufin O-deethylase and porphyrin analysis in chicken embryo hepatocyte cultures with a fluorescence multiwell plate reader. Analytical Biochemistry, 211, 102-112.
19. Krokos, F., Creaser, C. S., Wright, C., and Startin, J. R., 1996. Levels of selected ortho and non-ortho polychlorinated biphenyls in UK retail milk. Chemosphere, 32, 667-673.
20. Murk, A. J., Jonas, A., Leonards, P. E. G., Denison, M. S., and Brouwer, A., 1996a, Application of the CALUX (Chemical Activated LUciferase gene expression) assay for measuring TCDD-equivalents in sediment, pore water and blood plasma samples. Organohaiogen Compounds, 27, 291-296.
21. Murk, A. J., legler, J., Denison, M. S., Giesy, J. P., guchte, C. van de, and Brouwer, A., 1996b, Chemical-Activated LUciferase gene expression (CALUX): a novel in vitro bioassay for Ah-receptor active compounds in sediments and pore water. Fundamental and Applied Toxicology, 33, 149-160.
22. NATO/CCMS (North Atlantic Treaty Organization, Committee on the Challenges of Modern Society), 1988, International toxicity equivalency factor (I-TEF) method of risk assessment for complex mixtures of dioxins and related compounds. Report No. 176 (Brussels: North Atlantic Treaty Organization).
23. Poland, A., and Knutson, J. C., 1982, 2,3,7,8-tetrachlorodibenzo-p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity. Annual Review of Pharmacology and Toxicology, 22, 517-542.
24. Safe, S., 1986, Comparative toxicology and mechanism of action of polychlorinated dibenzo-p-dioxins and dibenzofurans. Annual Review of Pharmacology and Toxicology, 26, 371-399.
25. Safe, S., 1987, Determination of 2,3,7,8-TCDD toxic equivalent factors (TEFs): support for the use of the in vitro AHH induction assay. Chemosphere, 16, 791-802.
26. Safe, S., 1990, Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs). Critical Reviews in Toxicology, 21, 51-88.
27. Safe, S. H., 1994, Polychlolrinated biphenyls (PCBs): environmental impact, biochemical and toxic responses, and implications for risk assessment. Critical Reviews in Toxicology, 24, 87-149.
28. Safe, S., Safe, L., and Mullin, M., 1987, Polychlorinated biphenyls: environmental occurrence and analysis. Polychlorinated biphenyls (PCBs): Mammalian and Environmental Toxicology, edited by S. Safe and O. Hutzinger, Environmental Toxin Series 1 (Berlin: Springer-Verlag), pp. 1-13.
29. Safe, S., Bandiera, S., Sawyer, T., Robertson, L., Safe, L., Parkinson, A., Thomas, P. E., Ryan, D. E., Reik, L. M., Levin, W., Denomme, M. A., and Fujita, T., 1985, PCBs: structure-function relationships and mechanism of action. Environmental Health Perspectives, 60, 47-56.
30. Sanderson, J. T., Aarts, J. M. M. J. G., Brouwer, A., Froese, K. L., Denison, M. S., and Giesy, J. P., 1996, Comparison of Ah-receptor-mediated luciferase and ethoxyresorufin O-deethylase induction in H4IIE cells: implications for their use as bioanalytical tools for the detection of polyhalogenated aromatic compounds. Toxicology and Applied Pharmacology, 137, 316-325.
31. Sawyer, T. W., Vatcher, A. D., and Safe, S., 1984, Comparative aryl hydrocarbon hydroxylase induction of commercial PCBs in Wistar rats and hepatoma H4IIE cells in culture. Chemosphere, 13, 695-701.
32. Schrenk, D., Lipp, H.-P., Wiesmuller, T., Hagenmaier, H., and Bock, K. W., 1991, Assessment of biological activities of mixtures of polychlorinated dibenzo-p-dioxins: comparison between defined mixtures and their constituents. Archives of Toxicology, 65, 114-118.
33. Tillitt, D. E., Giesy, J. P., and Ankley, G. T., 1991, Characterization of the H4IIE rat hepatoma cell bioassay as a tool for assessing toxic potency of planar halogenated hydrocarbons in environmental samples. Environmental Science and Technology, 25, 87-92.
34. Tuinstra, L. G., Traag, W. A., van Rhijn, J. A., and v.d. Spreng, P. F., 1994, The Dutch PCB/dioxin study: development of a method for the determination of dioxins, planar and other PCBs in human milk. Chemosphere, 29, 1859-1875.
35. Wiebel, F. J., and Cikryt, P., 1990, Dexamethasone-mediated potentiation of P450IA1 induction in H4IIEC3/T hepatoma cells is dependant on a time-consuming process and associated with induction of the Ah receptor. Chemico-Biological Interactions, 76, 307-320