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Volumn 9, Issue 31, 2010, Pages 5004-5012

The effects of Momordica charantia on the liver in streptozotocin-induced diabetes in neonatal rats

Author keywords

Diabetes; Liver; Momordica charantia; Neonatal rat

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; GLIBENCLAMIDE; GLUCOSE; INSULIN; MALONALDEHYDE; MOMORDICA CHARANTIA EXTRACT;

EID: 77956118312     PISSN: 16845315     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (43)

References (42)
  • 1
    • 33750348125 scopus 로고    scopus 로고
    • Some toxicological studies of Momordica charantia L. on albino rats in normal and alloxan diabetic. rats
    • Abdelsattarelbatran S, Elgengaihi S, Elshabrawy O (2006). Some toxicological studies of Momordica charantia L. on albino rats in normal and alloxan diabetic. rats. J. Ethnopharmacol. 108: 236-242.
    • (2006) J. Ethnopharmacol , vol.108 , pp. 236-242
    • Abdelsattarelbatran, S.1    Elgengaihi, S.2    Elshabrawy, O.3
  • 2
    • 0033107711 scopus 로고    scopus 로고
    • Effect of Momordica charantia (Karolla) extracts on fasting and postprandial serum glucose levels in NIDDM patients
    • Ahmad N, Hassan MR, Halder H, Bennoor KS (1999). Effect of Momordica charantia (Karolla) extracts on fasting and postprandial serum glucose levels in NIDDM patients. Bangladesh Med. Res. Counc. Bull. 25: 11-13.
    • (1999) Bangladesh Med. Res. Counc. Bull , vol.25 , pp. 11-13
    • Ahmad, N.1    Hassan, M.R.2    Halder, H.3    Bennoor, K.S.4
  • 3
    • 0032104490 scopus 로고    scopus 로고
    • Effects of Momordica charantia fruit juice on islet morphology in the pancreas of the streptozotocin-diabetic rat
    • Ahmed I, Adeghate E, Sharma AK, Pallot DJ, Singh J (1998). Effects of Momordica charantia fruit juice on islet morphology in the pancreas of the streptozotocin-diabetic rat. Diabetes Res. Clin. Pract. 40: 145-151.
    • (1998) Diabetes Res. Clin. Pract , vol.40 , pp. 145-151
    • Ahmed, I.1    Adeghate, E.2    Sharma, A.K.3    Pallot, D.J.4    Singh, J.5
  • 4
    • 34447646909 scopus 로고    scopus 로고
    • Lipid peroxidation and serum antioxidant enzymes in patients with type 2 diabetes mellitus
    • Ahmed FN, Naqvi FN, Shafiq F (2006). Lipid peroxidation and serum antioxidant enzymes in patients with type 2 diabetes mellitus. Ann. NY. Acad. Sci. 1084: 481-489.
    • (2006) Ann. NY. Acad. Sci , vol.1084 , pp. 481-489
    • Ahmed, F.N.1    Naqvi, F.N.2    Shafiq, F.3
  • 5
    • 33751249006 scopus 로고    scopus 로고
    • Review Diabetes mellitus and its treatment
    • Bastaki S (2005). Review Diabetes mellitus and its treatment. Int. J. Diabetes Metabol. 13: 111-134.
    • (2005) Int. J. Diabetes Metabol , vol.13 , pp. 111-134
    • Bastaki, S.1
  • 6
    • 0032913309 scopus 로고    scopus 로고
    • Role of oxidative stress in diabetic complications: A new perspective on an old paradigm
    • Baynes JW, Thorpe SR (1999). Role of oxidative stress in diabetic complications: a new perspective on an old paradigm. Diabetes, 48: 1-9.
    • (1999) Diabetes , vol.48 , pp. 1-9
    • Baynes, J.W.1    Thorpe, S.R.2
  • 7
    • 16644369717 scopus 로고    scopus 로고
    • Effect of Aloe vera leaf gel and pulp extracts on the liver in type-II diabetic rat models
    • Can A, Akev N, Ozsoy N, Bolkent S, Arda BP, Yanardag R, Okyar A (2004). Effect of Aloe vera leaf gel and pulp extracts on the liver in type-II diabetic rat models. Biol. Pharm. Bull. 27: 694-698.
    • (2004) Biol. Pharm. Bull , vol.27 , pp. 694-698
    • Can, A.1    Akev, N.2    Ozsoy, N.3    Bolkent, S.4    Arda, B.P.5    Yanardag, R.6    Okyar, A.7
  • 8
    • 11144233279 scopus 로고    scopus 로고
    • Effect of Momordica charantia on lipid profile and oral glucose tolerance in diabetic rats
    • Chaturvedi P, George S, Milinganyo M, Tripathi YB (2004). Effect of Momordica charantia on lipid profile and oral glucose tolerance in diabetic rats. Phytother. Res. 18: 954-956.
    • (2004) Phytother. Res , vol.18 , pp. 954-956
    • Chaturvedi, P.1    George, S.2    Milinganyo, M.3    Tripathi, Y.B.4
  • 9
    • 0037385896 scopus 로고    scopus 로고
    • Bitter Melon (Momordica charantia) Reduces Adiposity, Lowers Serum Insulin and Normalizes Glucose Tolerance in Rats Fed a High Fat Diet
    • Chen Q, Chan LLY, Li ETS (2003). Bitter Melon (Momordica charantia) Reduces Adiposity, Lowers Serum Insulin and Normalizes Glucose Tolerance in Rats Fed a High Fat Diet. J. Nutr. 133: 1088-1093.
    • (2003) J. Nutr , vol.133 , pp. 1088-1093
    • Chen, Q.1    Chan, L.L.Y.2    Li, E.T.S.3
  • 10
    • 35748941961 scopus 로고    scopus 로고
    • An experimental evaluation of the antidiabetic and antilipidemic properties of a standardized Momordica charantia fruit extract
    • Fernandes NPC, Lagishetty CV, Panda VS, Naik SR (2007). An experimental evaluation of the antidiabetic and antilipidemic properties of a standardized Momordica charantia fruit extract. BMC Complement. Altern. Med. 7: 29.
    • (2007) BMC Complement. Altern. Med , vol.7 , pp. 29
    • Fernandes, N.P.C.1    Lagishetty, C.V.2    Panda, V.S.3    Naik, S.R.4
  • 11
    • 26244447838 scopus 로고    scopus 로고
    • Beneficial effect and mechanism of action of Momordica Charantia in the treatment of diabetes mellitus: A mini review
    • Garau C, Singh J, Cummings E (2003). Beneficial effect and mechanism of action of Momordica Charantia in the treatment of diabetes mellitus: a mini review. Int. J. Diabetes Metabol. 11: 46-55.
    • (2003) Int. J. Diabetes Metabol , vol.11 , pp. 46-55
    • Garau, C.1    Singh, J.2    Cummings, E.3
  • 12
    • 3042636409 scopus 로고    scopus 로고
    • P Glucose Homeostasis Tissue Transcript Content of Insulin Signaling Intermediates in Four Inbred of Mice: C57BL/6, C57BLKS/6, DBA/2, and 129X1
    • Goren HJ, Kulkarni RN, Kahn CR (2004). P Glucose Homeostasis Tissue Transcript Content of Insulin Signaling Intermediates in Four Inbred of Mice: C57BL/6, C57BLKS/6, DBA/2, and 129X1. Endocrinol.145:3307-3332.
    • (2004) Endocrinol , vol.145 , pp. 3307-3332
    • Goren, H.J.1    Kulkarni, R.N.2    Kahn, C.R.3
  • 13
    • 2942538292 scopus 로고    scopus 로고
    • Pharmacological actions and potential uses of Momordica charantia: A review
    • Grover JK, Yadav SP (2004). Pharmacological actions and potential uses of Momordica charantia: a review. J. Ethnopharmacol. 93: 123-132.
    • (2004) J. Ethnopharmacol , vol.93 , pp. 123-132
    • Grover, J.K.1    Yadav, S.P.2
  • 15
    • 0035136395 scopus 로고    scopus 로고
    • The sulfonylurea glimepiride regulates intracellular routing of the insulin-receptor complexes through their interaction with specific protein kinase C isoforms
    • Hribal ML, D'Alfonso R, Giovannone B, Lauro D, Liu YY, Borboni P, Federici M, Lauro R, Sesti G (2001). The sulfonylurea glimepiride regulates intracellular routing of the insulin-receptor complexes through their interaction with specific protein kinase C isoforms. Mol. Pharmacol. 59: 322-330.
    • (2001) Mol. Pharmacol , vol.59 , pp. 322-330
    • Hribal, M.L.1    D'alfonso, R.2    Giovannone, B.3    Lauro, D.4    Liu, Y.Y.5    Borboni, P.6    Federici, M.7    Lauro, R.8    Sesti, G.9
  • 16
    • 33746386763 scopus 로고    scopus 로고
    • Bitter gourd (Momordica Charantia): A dietary approach to hyperglycemia
    • Krawinkel MB, Keding GB (2006). Bitter gourd (Momordica Charantia): A dietary approach to hyperglycemia. Nutr. Rev. 64: 331-337.
    • (2006) Nutr. Rev , vol.64 , pp. 331-337
    • Krawinkel, M.B.1    Keding, G.B.2
  • 17
    • 33645239789 scopus 로고    scopus 로고
    • Antidiabetic activity of SMK001, a poly herbal formula in streptozotocin induced diabetic rats: Therapeutic study
    • Kim JD, Kang SM, Seo BI, Choi HY, Choi HS, Ku SK (2006). Antidiabetic activity of SMK001, a poly herbal formula in streptozotocin induced diabetic rats: therapeutic study. Biol. Pharm. Bull. 29: 477-482.
    • (2006) Biol. Pharm. Bull , vol.29 , pp. 477-482
    • Kim, J.D.1    Kang, S.M.2    Seo, B.I.3    Choi, H.Y.4    Choi, H.S.5    Ku, S.K.6
  • 18
    • 22244458309 scopus 로고    scopus 로고
    • Serum lipid peroxidation and antioxidant enzyme levels in male and female diabetic patients
    • Mahboob M, Rahman MF, Grover P (2005). Serum lipid peroxidation and antioxidant enzyme levels in male and female diabetic patients. Singapore. Med. J. 46: 322-324.
    • (2005) Singapore. Med. J , vol.46 , pp. 322-324
    • Mahboob, M.1    Rahman, M.F.2    Grover, P.3
  • 19
    • 33847157168 scopus 로고    scopus 로고
    • Effect of exogenous ATP on Momordica charantia Linn. (Cucurbitaceae) induced inhibition of D-glucose, L-tyrosine and fluid transport across rat everted intestinal sacs in vitro
    • Mahomoodally MF, Gurib-Fakim A, Subratty AH (2007). Effect of exogenous ATP on Momordica charantia Linn. (Cucurbitaceae) induced inhibition of D-glucose, L-tyrosine and fluid transport across rat everted intestinal sacs in vitro. J. Ethnopharmacol. 110: 257-263.
    • (2007) J. Ethnopharmacol , vol.110 , pp. 257-263
    • Mahomoodally, M.F.1    Gurib-Fakim, A.2    Subratty, A.H.3
  • 20
    • 3242813810 scopus 로고    scopus 로고
    • Does bitter melon contain an activator of AMP activated kinase
    • McCarty MF (2004). Does bitter melon contain an activator of AMP activated kinase? Med. Hypotheses, 63: 340-343.
    • (2004) Med. Hypotheses , vol.63 , pp. 340-343
    • McCarty, M.F.1
  • 22
    • 69549108234 scopus 로고    scopus 로고
    • Antioxidant triterpenoids from the stems of Momordica charantia
    • Liu C, Yen M, Tsang S, Gan K, Hsu H, Lin C (2010). Antioxidant triterpenoids from the stems of Momordica charantia. Food Chem. Toxicol. 118: 751-756.
    • (2010) Food Chem. Toxicol , vol.118 , pp. 751-756
    • Liu, C.1    Yen, M.2    Tsang, S.3    Gan, K.4    Hsu, H.5    Lin, C.6
  • 23
    • 1442276960 scopus 로고    scopus 로고
    • Activin A and betacellulin: Effect on regeneration of pancreatic beta-cells in neonatal streptozotocintreated rats
    • Li L, Yi Z, Seno M, Kojima I (2004). Activin A and betacellulin: effect on regeneration of pancreatic beta-cells in neonatal streptozotocintreated rats. Diabetes, 53: 608-615.
    • (2004) Diabetes , vol.53 , pp. 608-615
    • Li, L.1    Yi, Z.2    Seno, M.3    Kojima, I.4
  • 24
    • 47149095278 scopus 로고    scopus 로고
    • B-cell apoptosis in type 2 diabetes: Quantitative and functional consequences
    • Lupi R, Del Prato S (2008). B-cell apoptosis in type 2 diabetes: quantitative and functional consequences. Diabetes Metab. 34: 56-64.
    • (2008) Diabetes Metab , vol.34 , pp. 56-64
    • Lupi, R.1    del Prato, S.2
  • 25
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • Ohkawa H, Ohishi N, Yagi K (1979). Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal. Biochem. 95: 351-358.
    • (1979) Anal. Biochem , vol.95 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 28
    • 21144434516 scopus 로고    scopus 로고
    • Beneficial effects of Momordica charantia seeds in the treatment of STZ-induced diabetes in experimental rats
    • Sathishsekar D, Subramanian S (2005). Beneficial effects of Momordica charantia seeds in the treatment of STZ-induced diabetes in experimental rats. Biol. Pharm. Bull. 28: 978-983.
    • (2005) Biol. Pharm. Bull , vol.28 , pp. 978-983
    • Sathishsekar, D.1    Subramanian, S.2
  • 30
    • 33846992288 scopus 로고    scopus 로고
    • Antioxidant and chemoprotective properties of Momordica charantia L. (bitter melon) fruit extract
    • Semiz A, Sen A (2007). Antioxidant and chemoprotective properties of Momordica charantia L. (bitter melon) fruit extract. Afr. J. Med. Med Sci. 6: 273-277.
    • (2007) Afr. J. Med. Med Sci , vol.6 , pp. 273-277
    • Semiz, A.1    Sen, A.2
  • 31
    • 64549141112 scopus 로고    scopus 로고
    • Momordica charantia extract on insulin resistance and the skeletal muscle GLUT4 protein in fructosefed rats
    • Shih C, Lin C, Lin W, Wu J (2009). Momordica charantia extract on insulin resistance and the skeletal muscle GLUT4 protein in fructosefed rats. J. Ethnopharmacol. 123: 82-90.
    • (2009) J. Ethnopharmacol , vol.123 , pp. 82-90
    • Shih, C.1    Lin, C.2    Lin, W.3    Wu, J.4
  • 32
    • 0033927667 scopus 로고    scopus 로고
    • Cellular mechanisms of insulin resistance
    • Shulman GI (2000). Cellular mechanisms of insulin resistance. J. Clin. Invest. 106: 171-176.
    • (2000) J. Clin. Invest , vol.106 , pp. 171-176
    • Shulman, G.I.1
  • 33
    • 0033801858 scopus 로고    scopus 로고
    • Role of bittergourd fruit juice in STZ-induced diabetic state in vivo and in vitro
    • Sitasawad SL, Shewade Y, Bhonde R (2000). Role of bittergourd fruit juice in STZ-induced diabetic state in vivo and in vitro. J. Ethnopharmacol. 73: 71-79.
    • (2000) J. Ethnopharmacol , vol.73 , pp. 71-79
    • Sitasawad, S.L.1    Shewade, Y.2    Bhonde, R.3
  • 34
    • 40449117390 scopus 로고    scopus 로고
    • Bitter gourd (Momordica charantia) improves insulin sensitivity by increasing skeletal muscle insulin-stimulated IRS-1 tyrosine phosphorylation in high-fat-fed rats
    • Sridhar MG, Vinayagamoorthi R, Arul Suyambunathan V, Bobby Z, Selvaraj N (2008). Bitter gourd (Momordica charantia) improves insulin sensitivity by increasing skeletal muscle insulin-stimulated IRS-1 tyrosine phosphorylation in high-fat-fed rats. Br. J. Nutr. 99: 806-812.
    • (2008) Br. J. Nutr , vol.99 , pp. 806-812
    • Sridhar, M.G.1    Vinayagamoorthi, R.2    Arul, S.V.3    Bobby, Z.4    Selvaraj, N.5
  • 39
    • 38049120884 scopus 로고    scopus 로고
    • Conjugated linoleic acid fails to worsen insulin resistance but induces hepatic steatosis in the presence of leptin in ob/ob mice
    • Wendel AA, Purushotham A, Liu L, Belury MA (2008). Conjugated linoleic acid fails to worsen insulin resistance but induces hepatic steatosis in the presence of leptin in ob/ob mice. J. Lipid Res. 49: 98-106.
    • (2008) J. Lipid Res , vol.49 , pp. 98-106
    • Wendel, A.A.1    Purushotham, A.2    Liu, L.3    Belury, M.A.4
  • 41
    • 36048966599 scopus 로고    scopus 로고
    • Antioxidant and free radical scavenging activities of wild bitter melon (Momordica charantia Linn. var. abbreviata Ser.) in Taiwan
    • Wu S, Ng L (2008). Antioxidant and free radical scavenging activities of wild bitter melon (Momordica charantia Linn. var. abbreviata Ser.) in Taiwan. LWT-Food Sci. Technol. 41: 323-330.
    • (2008) LWT-Food Sci. Technol , vol.41 , pp. 323-330
    • Wu, S.1    Ng, L.2
  • 42
    • 84862805089 scopus 로고    scopus 로고
    • The characterization of highfat diet and multiple low-dose streptozotocin induced type 2 diabetes rat model
    • Zhang M, Lv X, Li J, Xu Z, Chen L (2008). The characterization of highfat diet and multiple low-dose streptozotocin induced type 2 diabetes rat model. Int. J. Exp. Diabetes Res. 7(4): 45.
    • (2008) Int. J. Exp. Diabetes Res , vol.7 , Issue.4 , pp. 45
    • Zhang, M.1    Lv, X.2    Li, J.3    Xu, Z.4    Chen, L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.