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Volumn 10, Issue 7, 2010, Pages 705-715

Paclitaxel efficacy is increased by parthenolide via nuclear factor-kappaB pathways in In Vitro and In Vivo human non-small cell lung cancer models

Author keywords

Caspase dependent; IKK; NF B; Synergy

Indexed keywords

I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PACLITAXEL; PARTHENOLIDE;

EID: 77956115773     PISSN: 15680096     EISSN: None     Source Type: Journal    
DOI: 10.2174/156800910793605776     Document Type: Article
Times cited : (24)

References (51)
  • 2
    • 33745199608 scopus 로고    scopus 로고
    • Expression of nuclear factor-kappaB and its clinical significance in nonsmall-cell lung cancer
    • Zhang, Z.; Ma, J.; Li, N.; Sun, N.; Wang, C. Expression of nuclear factor-kappaB and its clinical significance in nonsmall-cell lung cancer. Ann Thorac Surg. 2006, 82, 243-248.
    • (2006) Ann Thorac Surg , vol.82 , pp. 243-248
    • Zhang, Z.1    Ma, J.2    Li, N.3    Sun, N.4    Wang, C.5
  • 3
    • 0033807007 scopus 로고    scopus 로고
    • Inhibition of NF-kappaB sensitizes non-small cell lung cancer cells to chemotherapy-induced apoptosis
    • Jones, D. R.; Broad, R. M.; Madrid, L. V.; Baldwin, A. S. Jr.; Mayo, M. W. Inhibition of NF-kappaB sensitizes non-small cell lung cancer cells to chemotherapy-induced apoptosis. Ann. Thorac Surg. 2000, 70, 930-936.
    • (2000) Ann. Thorac Surg , vol.70 , pp. 930-936
    • Jones, D.R.1    Broad, R.M.2    Madrid, L.V.3    Baldwin Jr., A.S.4    Mayo, M.W.5
  • 4
    • 77951240675 scopus 로고    scopus 로고
    • Chemosensitization in non-small cell lung cancer cells by IKK inhibitor occurs via NF-kappaB and mitochondrial cytochrome c cascade
    • Jin, X.; Lin, Q.; Zhang, D.; Zhang, M.; Wang, Z.; Guo, Z.; Peng, M.; Deng, C.; Guo, C. Chemosensitization in non-small cell lung cancer cells by IKK inhibitor occurs via NF-kappaB and mitochondrial cytochrome c cascade. J. Cell Mol. Med. 2009, 13, 4596-4607.
    • (2009) J. Cell Mol. Med , vol.13 , pp. 4596-4607
    • Jin, X.1    Lin, Q.2    Zhang, D.3    Zhang, M.4    Wang, Z.5    Guo, Z.6    Peng, M.7    Deng, C.8    Guo, C.9
  • 5
    • 0033596121 scopus 로고    scopus 로고
    • Activators and target genes of Rel/NF-kappaB transcription factors
    • Pahl, H. L. Activators and target genes of Rel/NF-kappaB transcription factors. Oncogene 1999, 18, 6853-6866.
    • (1999) Oncogene , vol.18 , pp. 6853-6866
    • Pahl, H.L.1
  • 6
    • 33645999706 scopus 로고    scopus 로고
    • NF-kappaB and IKK as therapeutic targets in cancer
    • Kim, H. J.; Hawke, N.; Baldwin, A. S. NF-kappaB and IKK as therapeutic targets in cancer. Cell Death Differ. 2006, 13, 738-747.
    • (2006) Cell Death Differ , vol.13 , pp. 738-747
    • Kim, H.J.1    Hawke, N.2    Baldwin, A.S.3
  • 11
    • 11144237891 scopus 로고    scopus 로고
    • Nuclear factor-kappaB nuclear localization is predictive of biochemical recurrence in patients with positive margin prostate cancer
    • Fradet, V.; Lessard, L.; Bégin, L. R.; Karakiewicz, P.; Masson, A. M.; Saad, F. Nuclear factor-kappaB nuclear localization is predictive of biochemical recurrence in patients with positive margin prostate cancer. Clin. Cancer Res. 2004, 10, 8460-8464.
    • (2004) Clin. Cancer Res , vol.10 , pp. 8460-8464
    • Fradet, V.1    Lessard, L.2    Bégin, L.R.3    Karakiewicz, P.4    Masson, A.M.5    Saad, F.6
  • 12
    • 36349003530 scopus 로고    scopus 로고
    • Combined prognostic value of both RelA and IkappaB-alpha expression in human non-small cell lung cancer
    • Zhang, D.; Jin, X.; Wang, F.; Wang, S.; Deng, C.; Gao, Z.; Guo, C. Combined prognostic value of both RelA and IkappaB-alpha expression in human non-small cell lung cancer. Ann. Surg. Oncol. 2007,14, 3581-3592.
    • (2007) Ann. Surg. Oncol , vol.14 , pp. 3581-3592
    • Zhang, D.1    Jin, X.2    Wang, F.3    Wang, S.4    Deng, C.5    Gao, Z.6    Guo, C.7
  • 13
    • 74049104750 scopus 로고    scopus 로고
    • High expression levels of IKKalpha and IKKbeta are necessary for the malignant properties of liver cancer
    • Jiang, R.; Xia, Y.; Li, J.; Deng, L.; Zhao, L.; Shi, J.; Wang, X.; Sun, B. High expression levels of IKKalpha and IKKbeta are necessary for the malignant properties of liver cancer. Int. J. Cancer 2010,126, 1263-1274.
    • (2010) Int. J. Cancer , vol.126 , pp. 1263-1274
    • Jiang, R.1    Xia, Y.2    Li, J.3    Deng, L.4    Zhao, L.5    Shi, J.6    Wang, X.7    Sun, B.8
  • 15
    • 33745870112 scopus 로고    scopus 로고
    • Parthenolide cooperates with NS398 to inhibit growth of human hepatocellular carcinoma cells through effects on apoptosis and G0-G1 cell cycle arrest
    • Ralstin, M. C.; Gage, E. A.; Yip-Schneider, M. T.; Klein, P. J.; Wiebke, E. A.; Schmidt, C. M. Parthenolide cooperates with NS398 to inhibit growth of human hepatocellular carcinoma cells through effects on apoptosis and G0-G1 cell cycle arrest. Mol. Cancer Res. 2006, 4, 387-399.
    • (2006) Mol. Cancer Res , vol.4 , pp. 387-399
    • Ralstin, M.C.1    Gage, E.A.2    Yip-Schneider, M.T.3    Klein, P.J.4    Wiebke, E.A.5    Schmidt, C.M.6
  • 16
    • 19644366033 scopus 로고    scopus 로고
    • Apoptosis induction by a novel retinoid-related molecule requires nuclear factor-kappaB activation
    • Farhana, L.; Dawson, M. I.; Fontana, J. A. Apoptosis induction by a novel retinoid-related molecule requires nuclear factor-kappaB activation. Cancer Res. 2005, 65, 4909-4917.
    • (2005) Cancer Res , vol.65 , pp. 4909-4917
    • Farhana, L.1    Dawson, M.I.2    Fontana, J.A.3
  • 17
    • 0033571108 scopus 로고    scopus 로고
    • The antiinflammatory sesquiterpene lactone parthenolide inhibits NF-kappa B by targeting the I kappa B kinase complex
    • Hehner, S. P.; Hofmann, T. G.; Dröge, W.; Schmitz, M. L. The antiinflammatory sesquiterpene lactone parthenolide inhibits NF-kappa B by targeting the I kappa B kinase complex. J. Immunol. 1999,163, 5617-5623.
    • (1999) J. Immunol , vol.163 , pp. 5617-5623
    • Hehner, S.P.1    Hofmann, T.G.2    Dröge, W.3    Schmitz, M.L.4
  • 18
    • 34247525963 scopus 로고    scopus 로고
    • Sesquiterpene lactone parthenolide suppresses tumor growth in a xenograft model of renal cell carcinoma by inhibiting the activation of NF-kappaB
    • Oka, D.; Nishimura, K.; Shiba, M.; Nakai, Y.; Arai, Y.; Nakayama, M.; Takayama, H.; Inoue, H.; Okuyama, A.; Nonomura, N. Sesquiterpene lactone parthenolide suppresses tumor growth in a xenograft model of renal cell carcinoma by inhibiting the activation of NF-kappaB. Int. J. Cancer 2007, 120, 2576-2581.
    • (2007) Int. J. Cancer , vol.120 , pp. 2576-2581
    • Oka, D.1    Nishimura, K.2    Shiba, M.3    Nakai, Y.4    Arai, Y.5    Nakayama, M.6    Takayama, H.7    Inoue, H.8    Okuyama, A.9    Nonomura, N.10
  • 19
    • 33846272165 scopus 로고    scopus 로고
    • Parthenolide, a natural inhibitor of Nuclear Factor-kappaB, inhibits lung colonization of murine osteosarcoma cells
    • Kishida, Y.; Yoshikawa, H.; Myoui, A. Parthenolide, a natural inhibitor of Nuclear Factor-kappaB, inhibits lung colonization of murine osteosarcoma cells. Clin. Cancer Res. 2007, 13, 59-67.
    • (2007) Clin. Cancer Res , vol.13 , pp. 59-67
    • Kishida, Y.1    Yoshikawa, H.2    Myoui, A.3
  • 24
    • 38949094884 scopus 로고    scopus 로고
    • Potential biomarkers involving IKK/RelA signal in early stage non-small cell lung cancer
    • Jin, X.; Wang, Z.; Qiu, L.; Zhang, D.; Guo, Z.; Gao, Z.; Deng, C.; Wang, F.; Wang, S.; Guo, C. Potential biomarkers involving IKK/RelA signal in early stage non-small cell lung cancer. Cancer Sci. 2008, 99, 582-589.
    • (2008) Cancer Sci , vol.99 , pp. 582-589
    • Jin, X.1    Wang, Z.2    Qiu, L.3    Zhang, D.4    Guo, Z.5    Gao, Z.6    Deng, C.7    Wang, F.8    Wang, S.9    Guo, C.10
  • 25
    • 8444230023 scopus 로고    scopus 로고
    • Antitumor activity of hydrophilic Paclitaxel copolymer prodrug using locoregional delivery in human orthotopic non-small cell lung cancer xenograft models
    • Zou, Y.; Fu, H.; Ghosh, S.; Farquhar, D.; Klostergaard, J. Antitumor activity of hydrophilic Paclitaxel copolymer prodrug using locoregional delivery in human orthotopic non-small cell lung cancer xenograft models. Clin. Cancer Res. 2004, 10, 7382-7391.
    • (2004) Clin. Cancer Res , vol.10 , pp. 7382-7391
    • Zou, Y.1    Fu, H.2    Ghosh, S.3    Farquhar, D.4    Klostergaard, J.5
  • 26
    • 18044376489 scopus 로고    scopus 로고
    • Parthenolide and sulindac cooperate to mediate growth suppression and inhibit the nuclear factor-kappa B pathway in pancreatic carcinoma cells
    • Yip-Schneider, M. T.; Nakshatri, H.; Sweeney, C. J.; Marshall, M. S.; Wiebke, E. A.; Schmidt, C. M. Parthenolide and sulindac cooperate to mediate growth suppression and inhibit the nuclear factor-kappa B pathway in pancreatic carcinoma cells. Mol. Cancer Ther. 2005,4, 587-594.
    • (2005) Mol. Cancer Ther , vol.4 , pp. 587-594
    • Yip-Schneider, M.T.1    Nakshatri, H.2    Sweeney, C.J.3    Marshall, M.S.4    Wiebke, E.A.5    Schmidt, C.M.6
  • 28
    • 0036164423 scopus 로고    scopus 로고
    • Inhibition of nuclear factor kappaB chemosensitizes non-small cell lung cancer through cytochrome c release and caspase activation
    • Jones, D. R.; Broad, R. M.; Comeau, L. D.; Parsons, S. J.; Mayo, M. W. Inhibition of nuclear factor kappaB chemosensitizes non-small cell lung cancer through cytochrome c release and caspase activation. J. Thorac. Cardiovasc. Surg. 2002, 123, 310-317.
    • (2002) J. Thorac. Cardiovasc. Surg , vol.123 , pp. 310-317
    • Jones, D.R.1    Broad, R.M.2    Comeau, L.D.3    Parsons, S.J.4    Mayo, M.W.5
  • 31
    • 1842558596 scopus 로고    scopus 로고
    • Molecular therapy to inhibit NFkappaB activation by transcription factor decoy oligonucleotides
    • Morishita, R.; Tomita, N.; Kaneda, Y.; Ogihara, T. Molecular therapy to inhibit NFkappaB activation by transcription factor decoy oligonucleotides. Curr. Opin. Pharmacol. 2004, 4, 139-146.
    • (2004) Curr. Opin. Pharmacol , vol.4 , pp. 139-146
    • Morishita, R.1    Tomita, N.2    Kaneda, Y.3    Ogihara, T.4
  • 34
    • 0346505340 scopus 로고    scopus 로고
    • The IKK NF-kappa B system: A treasure trove for drug development
    • Karin, M.; Yamamoto, Y.; Wang, Q. M. The IKK NF-kappa B system: a treasure trove for drug development. Nat. Rev. Drug Discov. 2004, 3, 17-26.
    • (2004) Nat. Rev. Drug Discov , vol.3 , pp. 17-26
    • Karin, M.1    Yamamoto, Y.2    Wang, Q.M.3
  • 36
    • 27244431774 scopus 로고    scopus 로고
    • Targeting histones and proteasomes: New strategies for the treatment of lymphoma
    • O'Connor, O. A. Targeting histones and proteasomes: new strategies for the treatment of lymphoma. J. Clin. Oncol. 2005, 23, 6429-6436.
    • (2005) J. Clin. Oncol , vol.23 , pp. 6429-6436
    • O'Connor, O.A.1
  • 37
    • 33847168466 scopus 로고    scopus 로고
    • IkappaB kinase inhibitors for treating auto-immune and inflammatory disorders: Potential and challenges
    • Strnad, J.; Burke, J. R. IkappaB kinase inhibitors for treating auto-immune and inflammatory disorders: potential and challenges. Trends Pharmacol. Sci. 2007, 28, 142-148.
    • (2007) Trends Pharmacol. Sci , vol.28 , pp. 142-148
    • Strnad, J.1    Burke, J.R.2
  • 38
    • 34548236254 scopus 로고    scopus 로고
    • LZAP, a putative tumor suppressor, selectively inhibits NF-kappaB
    • Wang, J.; An, H.; Mayo, M. W.; Baldwin, A. S.; Yarbrough, W. G. LZAP, a putative tumor suppressor, selectively inhibits NF-kappaB. Cancer Cell. 2007, 12, 239-251.
    • (2007) Cancer Cell , vol.12 , pp. 239-251
    • Wang, J.1    An, H.2    Mayo, M.W.3    Baldwin, A.S.4    Yarbrough, W.G.5
  • 39
    • 0035577760 scopus 로고    scopus 로고
    • Retinoid-related molecules induce cytochrome c release and apoptosis through activation of c-Jun NH(2)-terminal kinase/p38 mitogen-activated protein kinases
    • Ortiz, M. A.; Lopez-Hernandez, F. J.; Bayon, Y.; Pfahl, M.; Piedrafita, F. J. Retinoid-related molecules induce cytochrome c release and apoptosis through activation of c-Jun NH(2)-terminal kinase/p38 mitogen-activated protein kinases. Cancer Res. 2001, 61, 8504-8512.
    • (2001) Cancer Res , vol.61 , pp. 8504-8512
    • Ortiz, M.A.1    Lopez-Hernandez, F.J.2    Bayon, Y.3    Pfahl, M.4    Piedrafita, F.J.5
  • 40
    • 0034662496 scopus 로고    scopus 로고
    • Factor-kappaB/IkappaB signaling pathway may contribute to the mediation of paclitaxel-induced apoptosis in solid tumor cells
    • Huang, Y.; Johnson, K. R.; Norris, J. S.; Fan, W. factor-kappaB/IkappaB signaling pathway may contribute to the mediation of paclitaxel-induced apoptosis in solid tumor cells. Cancer Res. 2000, 60, 4426-4432.
    • (2000) Cancer Res , vol.60 , pp. 4426-4432
    • Huang, Y.1    Johnson, K.R.2    Norris, J.S.3    Fan, W.4
  • 41
    • 0036006698 scopus 로고    scopus 로고
    • IkappaB kinase activation is involved in regulation of paclitaxel-induced apoptosis in human tumor cell lines. Mol
    • Huang, Y.; Fan, W. IkappaB kinase activation is involved in regulation of paclitaxel-induced apoptosis in human tumor cell lines. Mol. Pharmacol. 2002, 61, 105-113.
    • (2002) Pharmacol , vol.61 , pp. 105-113
    • Huang, Y.1    Fan, W.2
  • 42
    • 0030614456 scopus 로고    scopus 로고
    • IkappaB alpha overexpression in human breast carcinoma MCF7 cells inhibits nuclear factor-kappaB activation but not tumor necrosis factor-alpha-induced apoptosis
    • Cai, Z.; Körner, M.; Tarantino, N.; Chouaib, S. IkappaB alpha overexpression in human breast carcinoma MCF7 cells inhibits nuclear factor-kappaB activation but not tumor necrosis factor-alpha-induced apoptosis. J. Biol. Chem. 1997, 272, 96-101.
    • (1997) J. Biol. Chem , vol.272 , pp. 96-101
    • Cai, Z.1    Körner, M.2    Tarantino, N.3    Chouaib, S.4
  • 43
    • 1442350558 scopus 로고    scopus 로고
    • Paclitaxel-induced apoptosis may occur without a prior G2/M-phase arrest
    • Dziadyk, J. M.; Sui, M.; Zhu, X.; Fan, W. Paclitaxel-induced apoptosis may occur without a prior G2/M-phase arrest. Anticancer Res. 2004,24, 27-36.
    • (2004) Anticancer Res , vol.24 , pp. 27-36
    • Dziadyk, J.M.1    Sui, M.2    Zhu, X.3    Fan, W.4
  • 44
    • 34249892217 scopus 로고    scopus 로고
    • Parthenolide inhibits IkappaB kinase, NF-kappaB activation, and inflammatory response in cystic fibrosis cells and mice
    • Saadane, A.; Masters, S.; DiDonato, J.; Li, J.; Berger, M. Parthenolide inhibits IkappaB kinase, NF-kappaB activation, and inflammatory response in cystic fibrosis cells and mice. Am. J. Respir. Cell. Mol. Biol. 2007, 36, 728-736.
    • (2007) Am. J. Respir. Cell. Mol. Biol , vol.36 , pp. 728-736
    • Saadane, A.1    Masters, S.2    Didonato, J.3    Li, J.4    Berger, M.5
  • 45
    • 0034671206 scopus 로고    scopus 로고
    • Chemotherapy triggers apoptosis in a caspase-8-dependent and mitochondria-controlled manner in the non-small cell lung cancer cell line NCI-H460
    • Ferreira, C. G.; Span, S. W.; Peters, G. J.; Kruyt, F. A.; Giaccone, G. Chemotherapy triggers apoptosis in a caspase-8-dependent and mitochondria-controlled manner in the non-small cell lung cancer cell line NCI-H460. Cancer Res. 2000, 60, 7133-7141.
    • (2000) Cancer Res , vol.60 , pp. 7133-7141
    • Ferreira, C.G.1    Span, S.W.2    Peters, G.J.3    Kruyt, F.A.4    Giaccone, G.5
  • 46
    • 18244392443 scopus 로고    scopus 로고
    • Cell death independent of caspases: A review
    • Bröker, L. E.; Kruyt, F. A.; Giaccone, G. Cell death independent of caspases: a review. Clin. Cancer Res. 2005, 11, 3155-3162.
    • (2005) Clin. Cancer Res , vol.11 , pp. 3155-3162
    • Bröker, L.E.1    Kruyt, F.A.2    Giaccone, G.3
  • 48
    • 67651160513 scopus 로고    scopus 로고
    • Nuclear factor-kappaB inhibition by parthenolide potentiates the efficacy of Taxol in non-small cell lung cancer in vitro and in vivo
    • Zhang, D.; Qiu, L.; Jin, X.; Guo, Z.; Guo, C. Nuclear factor-kappaB inhibition by parthenolide potentiates the efficacy of Taxol in non-small cell lung cancer in vitro and in vivo. Mol. Cancer Res. 2009,7,1139-1149.
    • (2009) Mol. Cancer Res , vol.7 , pp. 1139-1149
    • Zhang, D.1    Qiu, L.2    Jin, X.3    Guo, Z.4    Guo, C.5
  • 49
    • 0035119798 scopus 로고    scopus 로고
    • Disruption of cell adhesion and caspase-mediated proteolysis of beta- and gamma-catenins and APC protein in paclitaxel-induced apoptosis
    • Ling, Y.; Zhong, Y.; Perez-Soler, R. Disruption of cell adhesion and caspase-mediated proteolysis of beta- and gamma-catenins and APC protein in paclitaxel-induced apoptosis. Mol. Pharmacol. 2001,59, 593-603.
    • (2001) Mol. Pharmacol , vol.59 , pp. 593-603
    • Ling, Y.1    Zhong, Y.2    Perez-Soler, R.3
  • 50
    • 6044240634 scopus 로고    scopus 로고
    • Antitumor agent parthenolide reverses resistance of breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through sustained activation of c-Jun N-terminal kinase
    • Nakshatri, H.; Rice, S. E.; Bhat-Nakshatri, P. Antitumor agent parthenolide reverses resistance of breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through sustained activation of c-Jun N-terminal kinase. Oncogene 2004, 23, 7330-7344.
    • (2004) Oncogene , vol.23 , pp. 7330-7344
    • Nakshatri, H.1    Rice, S.E.2    Bhat-Nakshatri, P.3
  • 51
    • 34848819086 scopus 로고    scopus 로고
    • American College of Chest Physicians. Lung cancer chemoprevention: ACCP evidence-based clinical practice guidelines (2nd Edition)
    • Gray, J.; Mao, J. T.; Szabo, E.; Kelley, M.; Kurie, J.; Bepler, G.; American College of Chest Physicians. Lung cancer chemoprevention: ACCP evidence-based clinical practice guidelines (2nd Edition). Chest 2007, 132, 56S-68S.
    • (2007) Chest , vol.132
    • Gray, J.1    Mao, J.T.2    Szabo, E.3    Kelley, M.4    Kurie, J.5    Bepler, G.6


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