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Volumn 132, Issue 3 SUPPL., 2007, Pages 56S-68S

Lung cancer chemoprevention: ACCP evidence-based clinical practice guidelines (2nd edition)

Author keywords

Acetyl salicylic acid; Apoptosis; Biomarkers; Chemoprevention; Cyclooxygenase 2 inhibitors; Lung cancer; Proliferation; Protein kinase C; Selenium; Signal transduction pathways; Tyrosine kinase inhibitors; Vitamin A; Vitamin E

Indexed keywords

ACETYLCYSTEINE; ACETYLSALICYLIC ACID; ALPHA TOCOPHEROL; BETA CAROTENE; ISOTRETINOIN; RETINOL; ANTINEOPLASTIC AGENT;

EID: 34848819086     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.07-1348     Document Type: Article
Times cited : (33)

References (120)
  • 1
    • 34848869894 scopus 로고    scopus 로고
    • Cancer facts and figures-2007. Atlanta, GA: American Cancer Society, 2007; 1-54
    • Cancer facts and figures-2007. Atlanta, GA: American Cancer Society, 2007; 1-54
  • 2
    • 18944392443 scopus 로고    scopus 로고
    • Cigarette smoking among adults-United States, 2003
    • Cigarette smoking among adults-United States, 2003. MMWR Morb Mortal Wkly Rep 2005; 54:509-513
    • (2005) MMWR Morb Mortal Wkly Rep , vol.54 , pp. 509-513
  • 3
    • 0034609239 scopus 로고    scopus 로고
    • Smoking, smoking cessation, and lung cancer in the UK since 1950: Combination of national statistics with two case-control studies
    • Peto R, Darby S, Deo H, et al. Smoking, smoking cessation, and lung cancer in the UK since 1950: combination of national statistics with two case-control studies. BMJ 2000; 321:323-329
    • (2000) BMJ , vol.321 , pp. 323-329
    • Peto, R.1    Darby, S.2    Deo, H.3
  • 4
    • 0033545342 scopus 로고    scopus 로고
    • Acute-phase proteins and other systemic responses to inflammation
    • Gabay C, Kushner I. Acute-phase proteins and other systemic responses to inflammation. N Engl J Med 1999; 340:448-454
    • (1999) N Engl J Med , vol.340 , pp. 448-454
    • Gabay, C.1    Kushner, I.2
  • 5
    • 78651056338 scopus 로고
    • Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin
    • Slaughter DP, Southwick HW, Smejkal W. Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin. Cancer 1953; 6:963-968
    • (1953) Cancer , vol.6 , pp. 963-968
    • Slaughter, D.P.1    Southwick, H.W.2    Smejkal, W.3
  • 6
    • 34848842695 scopus 로고    scopus 로고
    • Cancer facts and figures-1995. Atlanta, GA: American Cancer Society, 1995
    • Cancer facts and figures-1995. Atlanta, GA: American Cancer Society, 1995
  • 7
    • 0033591014 scopus 로고    scopus 로고
    • Annual report to the nation on the status of cancer, 1973-1996, with a special section on lung cancer and tobacco smoking
    • Wingo PA, Ries LA, Giovino GA, et al. Annual report to the nation on the status of cancer, 1973-1996, with a special section on lung cancer and tobacco smoking. J Natl Cancer Inst 1999; 91:675-690
    • (1999) J Natl Cancer Inst , vol.91 , pp. 675-690
    • Wingo, P.A.1    Ries, L.A.2    Giovino, G.A.3
  • 9
    • 18344399696 scopus 로고    scopus 로고
    • Group behavior therapy programmes for smoking cessation
    • CD001007
    • Stead L, Lancaster T. Group behavior therapy programmes for smoking cessation. Cochrane Database Syst Rev 2002; (3):CD001007
    • (2002) Cochrane Database Syst Rev , Issue.3
    • Stead, L.1    Lancaster, T.2
  • 11
    • 0033765273 scopus 로고    scopus 로고
    • US public health service clinical practice guideline: Treating tobacco use and dependence
    • Fiore MC. US public health service clinical practice guideline: treating tobacco use and dependence. Respir Care 2000; 45:1200-1262
    • (2000) Respir Care , vol.45 , pp. 1200-1262
    • Fiore, M.C.1
  • 12
    • 0033662997 scopus 로고    scopus 로고
    • Smoking cessation guidelines for health professionals: An update; Health Education Authority
    • West R, McNeill A, Raw M. Smoking cessation guidelines for health professionals: an update; Health Education Authority. Thorax 2000; 55:987-999
    • (2000) Thorax , vol.55 , pp. 987-999
    • West, R.1    McNeill, A.2    Raw, M.3
  • 13
    • 0030720886 scopus 로고    scopus 로고
    • A comparison of sustained-release bupropion and placebo for smoking cessation
    • Hurt RD, Sachs DP, Glover ED, et al. A comparison of sustained-release bupropion and placebo for smoking cessation. N Engl J Med 1997; 337:1195-1202
    • (1997) N Engl J Med , vol.337 , pp. 1195-1202
    • Hurt, R.D.1    Sachs, D.P.2    Glover, E.D.3
  • 15
    • 33745614361 scopus 로고    scopus 로고
    • Varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs sustained-release bupropion and placebo for smoking cessation: A randomized controlled trial
    • Gonzales D, Rennard SI, Nides M, et al. Varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs sustained-release bupropion and placebo for smoking cessation: a randomized controlled trial. JAMA 2006; 296:47-55
    • (2006) JAMA , vol.296 , pp. 47-55
    • Gonzales, D.1    Rennard, S.I.2    Nides, M.3
  • 16
    • 33745611449 scopus 로고    scopus 로고
    • Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: A randomized controlled trial
    • Jorenby DE, Hays JT, Rigotti NA, et al. Efficacy of varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, vs placebo or sustained-release bupropion for smoking cessation: a randomized controlled trial. JAMA 2006; 296:56-63
    • (2006) JAMA , vol.296 , pp. 56-63
    • Jorenby, D.E.1    Hays, J.T.2    Rigotti, N.A.3
  • 18
    • 0025701098 scopus 로고    scopus 로고
    • The Surgeon General's 1990 report on the health benefits of smoking cessation. Executive summary. MMWR Recomm Rep 1990; 39:i-xv, 1-12
    • The Surgeon General's 1990 report on the health benefits of smoking cessation. Executive summary. MMWR Recomm Rep 1990; 39:i-xv, 1-12
  • 19
    • 34248552496 scopus 로고    scopus 로고
    • Chemoprevention for lung cancer
    • Sendowski M, Bepler G. Chemoprevention for lung cancer. Oncol Spectr 2002; 3:116-126
    • (2002) Oncol Spectr , vol.3 , pp. 116-126
    • Sendowski, M.1    Bepler, G.2
  • 20
    • 0000147542 scopus 로고    scopus 로고
    • Recent advances in chemoprevention of cancer
    • Hong WK, Sporn MB. Recent advances in chemoprevention of cancer. Science 1997; 278:1073-1077
    • (1997) Science , vol.278 , pp. 1073-1077
    • Hong, W.K.1    Sporn, M.B.2
  • 22
    • 19844373387 scopus 로고    scopus 로고
    • Epidemiology of lung cancer: Looking to the future
    • Alberg AJ, Brock MV, Samet JM. Epidemiology of lung cancer: looking to the future. J Clin Oncol 2005; 23:3175-3185
    • (2005) J Clin Oncol , vol.23 , pp. 3175-3185
    • Alberg, A.J.1    Brock, M.V.2    Samet, J.M.3
  • 23
    • 76549257892 scopus 로고
    • Tobacco smoking as a possible etiologic factor in bronchiogenic carcinoma: A study of 684 proved cases
    • Wynder EL, Graham EA. Tobacco smoking as a possible etiologic factor in bronchiogenic carcinoma: a study of 684 proved cases. J Am Med Assoc 1950; 143:329-336
    • (1950) J Am Med Assoc , vol.143 , pp. 329-336
    • Wynder, E.L.1    Graham, E.A.2
  • 24
    • 0000415087 scopus 로고
    • Cancer and tobacco smoking: A preliminary report
    • Levin ML, Goldstein H, Gerhardt PR. Cancer and tobacco smoking: a preliminary report. J Am Med Assoc 1950; 143:336-338
    • (1950) J Am Med Assoc , vol.143 , pp. 336-338
    • Levin, M.L.1    Goldstein, H.2    Gerhardt, P.R.3
  • 25
    • 0008376153 scopus 로고
    • Smoking and carcinoma of the lung: Preliminary report
    • Doll R, Hill AB. Smoking and carcinoma of the lung: preliminary report. BMJ 1950; 2:739-748
    • (1950) BMJ , vol.2 , pp. 739-748
    • Doll, R.1    Hill, A.B.2
  • 26
    • 84939218739 scopus 로고
    • The mortality of doctors in relation to their smoking habits: A preliminary report
    • Doll R, Hill AB. The mortality of doctors in relation to their smoking habits: a preliminary report. BMJ 1954; 4877:1451-1455
    • (1954) BMJ , vol.4877 , pp. 1451-1455
    • Doll, R.1    Hill, A.B.2
  • 27
    • 24944452471 scopus 로고
    • Excessive cigarette smoking
    • Burney LE. Excessive cigarette smoking. Public Health Rep 1957; 72:786
    • (1957) Public Health Rep , vol.72 , pp. 786
    • Burney, L.E.1
  • 28
    • 0001545698 scopus 로고
    • Smoking and lung cancer: A statement of the Public Health Service
    • Burney LE. Smoking and lung cancer: a statement of the Public Health Service. JAMA 1959; 171:1829-1837
    • (1959) JAMA , vol.171 , pp. 1829-1837
    • Burney, L.E.1
  • 29
    • 84937090705 scopus 로고
    • Smoking and lung cancer: Recent evidence and a discussion of some questions
    • Cornfield J, Haenszel W, Hammond EC, et al. Smoking and lung cancer: recent evidence and a discussion of some questions. J Natl Cancer Inst 1959; 22:173-203
    • (1959) J Natl Cancer Inst , vol.22 , pp. 173-203
    • Cornfield, J.1    Haenszel, W.2    Hammond, E.C.3
  • 30
    • 1342288920 scopus 로고    scopus 로고
    • Chemoprevention of lung cancer: From biology to clinical reality
    • Winterhalder RC, Hirsch FR, Kotantoulas GK, et al. Chemoprevention of lung cancer: from biology to clinical reality. Ann Oncol 2004; 15:185-196
    • (2004) Ann Oncol , vol.15 , pp. 185-196
    • Winterhalder, R.C.1    Hirsch, F.R.2    Kotantoulas, G.K.3
  • 32
    • 12244274645 scopus 로고    scopus 로고
    • The natural course of preneoplastic lesions in bronchial epithelium
    • Breuer RH, Pasic A, Smit EF, et al. The natural course of preneoplastic lesions in bronchial epithelium. Clin Cancer Res 2005; 11:537-543
    • (2005) Clin Cancer Res , vol.11 , pp. 537-543
    • Breuer, R.H.1    Pasic, A.2    Smit, E.F.3
  • 33
    • 0033590626 scopus 로고    scopus 로고
    • Sequential molecular abnormalities are involved in the multistage development of squamous cell lung carcinoma
    • Wistuba II, Behrens C, Milchgrub S, et al. Sequential molecular abnormalities are involved in the multistage development of squamous cell lung carcinoma. Oncogene 1999; 18:643-650
    • (1999) Oncogene , vol.18 , pp. 643-650
    • Wistuba, I.I.1    Behrens, C.2    Milchgrub, S.3
  • 34
    • 4944241536 scopus 로고    scopus 로고
    • Biological features of bronchial squamous dysplasia followed up by autofluorescence bronchoscopy
    • Hoshino H, Shibuya K, Chiyo M, et al. Biological features of bronchial squamous dysplasia followed up by autofluorescence bronchoscopy. Lung Cancer 2004; 46:187-196
    • (2004) Lung Cancer , vol.46 , pp. 187-196
    • Hoshino, H.1    Shibuya, K.2    Chiyo, M.3
  • 35
    • 0015965209 scopus 로고
    • Development of carcinoma of the lung as reflected in exfoliated cells
    • Saccomanno G, Archer VE, Auerbach O, et al. Development of carcinoma of the lung as reflected in exfoliated cells. Cancer 1974; 33:256-270
    • (1974) Cancer , vol.33 , pp. 256-270
    • Saccomanno, G.1    Archer, V.E.2    Auerbach, O.3
  • 36
    • 22044447083 scopus 로고    scopus 로고
    • High prevalence of occult endobronchial malignancy in high risk patients with moderate sputum atypia
    • Kennedy TC, Franklin WA, Prindiville SA, et al. High prevalence of occult endobronchial malignancy in high risk patients with moderate sputum atypia. Lung Cancer 2005; 49:187-191
    • (2005) Lung Cancer , vol.49 , pp. 187-191
    • Kennedy, T.C.1    Franklin, W.A.2    Prindiville, S.A.3
  • 37
    • 10744230430 scopus 로고    scopus 로고
    • Sputum cytological atypia as a predictor of incident lung cancer in a cohort of heavy smokers with airflow obstruction
    • Prindiville SA, Byers T, Hirsch FR, et al. Sputum cytological atypia as a predictor of incident lung cancer in a cohort of heavy smokers with airflow obstruction. Cancer Epidemiol Biomarkers Prev 2003; 12:987-993
    • (2003) Cancer Epidemiol Biomarkers Prev , vol.12 , pp. 987-993
    • Prindiville, S.A.1    Byers, T.2    Hirsch, F.R.3
  • 38
    • 0022493426 scopus 로고
    • Sputum cytopathology: Use and potential in monitoring the workplace environment by screening for biological effects of exposure
    • Frost JK, Ball WC Jr, Levin ML, et al. Sputum cytopathology: use and potential in monitoring the workplace environment by screening for biological effects of exposure. J Occup Med 1986; 28:692-703
    • (1986) J Occup Med , vol.28 , pp. 692-703
    • Frost, J.K.1    Ball Jr, W.C.2    Levin, M.L.3
  • 39
    • 0032538039 scopus 로고    scopus 로고
    • Second lung cancers in patients after treatment for an initial lung cancer
    • Johnson BE. Second lung cancers in patients after treatment for an initial lung cancer. J Natl Cancer Inst 1998; 90:1335-1345
    • (1998) J Natl Cancer Inst , vol.90 , pp. 1335-1345
    • Johnson, B.E.1
  • 40
    • 0028122608 scopus 로고
    • The Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study in Finland
    • Blumberg J, Block C. The Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study in Finland. Nutr Rev 1994; 52:242-245
    • (1994) Nutr Rev , vol.52 , pp. 242-245
    • Blumberg, J.1    Block, C.2
  • 41
    • 0345157579 scopus 로고    scopus 로고
    • Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease
    • Hennekens CH, Buring JE, Manson JE, et al. Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease. N Engl J Med 1996; 334:1145-1149
    • (1996) N Engl J Med , vol.334 , pp. 1145-1149
    • Hennekens, C.H.1    Buring, J.E.2    Manson, J.E.3
  • 42
    • 0033572468 scopus 로고    scopus 로고
    • Beta-carotene supplementation and incidence of cancer and cardiovascular disease: The Women's Health Study
    • Lee IM, Cook NR, Manson JE, et al. Beta-carotene supplementation and incidence of cancer and cardiovascular disease: the Women's Health Study. J Natl Cancer Inst 1999; 91:2102-2106
    • (1999) J Natl Cancer Inst , vol.91 , pp. 2102-2106
    • Lee, I.M.1    Cook, N.R.2    Manson, J.E.3
  • 43
    • 20044383911 scopus 로고    scopus 로고
    • Effects of long-term vitamin E supplementation on cardiovascular events and cancer: A randomized controlled trial
    • Lonn E, Bosch J, Yusuf S, et al. Effects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trial. JAMA 2005; 293:1338-1347
    • (2005) JAMA , vol.293 , pp. 1338-1347
    • Lonn, E.1    Bosch, J.2    Yusuf, S.3
  • 44
    • 21444438990 scopus 로고    scopus 로고
    • Vitamin E in the primary prevention of cardiovascular disease and cancer: The Women's Health Study; a randomized controlled trial
    • Lee IM, Cook NR, Gaziano JM, et al. Vitamin E in the primary prevention of cardiovascular disease and cancer: the Women's Health Study; a randomized controlled trial. JAMA 2005; 294:56-65
    • (2005) JAMA , vol.294 , pp. 56-65
    • Lee, I.M.1    Cook, N.R.2    Gaziano, J.M.3
  • 45
    • 9244262406 scopus 로고    scopus 로고
    • Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease
    • Omenn GS, Goodman GE, Thornquist MD, et al. Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease. N Engl J Med 1996; 334:1150-1155
    • (1996) N Engl J Med , vol.334 , pp. 1150-1155
    • Omenn, G.S.1    Goodman, G.E.2    Thornquist, M.D.3
  • 46
    • 0035906224 scopus 로고    scopus 로고
    • Randomized phase III intergroup trial of isotretinoin to prevent second primary tumors in stage I non-small-cell lung cancer
    • Lippman SM, Lee JJ, Karp DD, et al. Randomized phase III intergroup trial of isotretinoin to prevent second primary tumors in stage I non-small-cell lung cancer. J Natl Cancer Inst 2001; 93:605-618
    • (2001) J Natl Cancer Inst , vol.93 , pp. 605-618
    • Lippman, S.M.1    Lee, J.J.2    Karp, D.D.3
  • 47
    • 0034697654 scopus 로고    scopus 로고
    • EUROSCAN, a randomized trial of vitamin A and N-acetylcysteine in patients with head and neck cancer or lung cancer: For the European Organization for Research and Treatment of Cancer Head and Neck and Lung Cancer Cooperative Groups
    • van Zandwijk N, Dalesio O, Pastorino U, et al. EUROSCAN, a randomized trial of vitamin A and N-acetylcysteine in patients with head and neck cancer or lung cancer: for the European Organization for Research and Treatment of Cancer Head and Neck and Lung Cancer Cooperative Groups. J Natl Cancer Inst 2000; 92:977-986
    • (2000) J Natl Cancer Inst , vol.92 , pp. 977-986
    • van Zandwijk, N.1    Dalesio, O.2    Pastorino, U.3
  • 48
    • 0023845856 scopus 로고
    • Randomised trial of prophylactic daily aspirin in British male doctors
    • Peto R, Gray R, Collins R, et al. Randomised trial of prophylactic daily aspirin in British male doctors. BMJ (Clin Res Ed) 1988; 296:313-316
    • (1988) BMJ (Clin Res Ed) , vol.296 , pp. 313-316
    • Peto, R.1    Gray, R.2    Collins, R.3
  • 49
    • 34848869295 scopus 로고    scopus 로고
    • Final report on the aspirin component of the ongoing Physicians' Health Study. Steering Committee of the Physicians' Health Study Research Group. N Engl J Med 1989; 321:129-135
    • Final report on the aspirin component of the ongoing Physicians' Health Study. Steering Committee of the Physicians' Health Study Research Group. N Engl J Med 1989; 321:129-135
  • 50
    • 21444450527 scopus 로고    scopus 로고
    • Low-dose aspirin in the primary prevention of cancer: The Women's Health Study; a randomized controlled trial
    • Cook NR, Lee IM, Gaziano JM, et al. Low-dose aspirin in the primary prevention of cancer: the Women's Health Study; a randomized controlled trial. JAMA 2005; 294:47-55
    • (2005) JAMA , vol.294 , pp. 47-55
    • Cook, N.R.1    Lee, I.M.2    Gaziano, J.M.3
  • 51
    • 0033520789 scopus 로고    scopus 로고
    • Multiple clonal abnormalities in the bronchial epithelium of patients with lung cancer
    • Park IW, Wistuba II, Maitra A, et al. Multiple clonal abnormalities in the bronchial epithelium of patients with lung cancer. J Natl Cancer Inst 1999; 91:1863-1868
    • (1999) J Natl Cancer Inst , vol.91 , pp. 1863-1868
    • Park, I.W.1
  • 52
    • 0034715979 scopus 로고    scopus 로고
    • The proliferation-specific human Ki-67 protein is a constituent of compact chromatin
    • Kreitz S, Fackelmayer FO, Gerdes J, et al. The proliferation-specific human Ki-67 protein is a constituent of compact chromatin. Exp Cell Res 2000; 261:284-292
    • (2000) Exp Cell Res , vol.261 , pp. 284-292
    • Kreitz, S.1    Fackelmayer, F.O.2    Gerdes, J.3
  • 53
    • 0034660087 scopus 로고    scopus 로고
    • The Ki-67 protein: Fascinating forms and an unknown function
    • Endl E, Gerdes J. The Ki-67 protein: fascinating forms and an unknown function. Exp Cell Res 2000; 257:231-237
    • (2000) Exp Cell Res , vol.257 , pp. 231-237
    • Endl, E.1    Gerdes, J.2
  • 54
    • 0027361196 scopus 로고
    • The cell proliferation- associated antigen of antibody Ki-67: A very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins
    • Schluter C, Duchrow M, Wohlenberg C, et al. The cell proliferation- associated antigen of antibody Ki-67: a very large, ubiquitous nuclear protein with numerous repeated elements, representing a new kind of cell cycle-maintaining proteins. J Cell Biol 1993; 123:513-522
    • (1993) J Cell Biol , vol.123 , pp. 513-522
    • Schluter, C.1    Duchrow, M.2    Wohlenberg, C.3
  • 55
    • 0030410931 scopus 로고    scopus 로고
    • Antisense oligonucleotides to proliferating cell nuclear antigen and Ki-67 inhibit human mesangial cell proliferation
    • Maeshima Y, Kashihara N, Sugiyama H, et al. Antisense oligonucleotides to proliferating cell nuclear antigen and Ki-67 inhibit human mesangial cell proliferation. J Am Soc Nephrol 1996; 7:2219-2229
    • (1996) J Am Soc Nephrol , vol.7 , pp. 2219-2229
    • Maeshima, Y.1    Kashihara, N.2    Sugiyama, H.3
  • 56
    • 0030111368 scopus 로고    scopus 로고
    • The role of MCM proteins in the cell cycle control of genome duplication
    • Kearsey SE, Maiorano D, Holmes EC, et al. The role of MCM proteins in the cell cycle control of genome duplication. Bioessays 1996; 18:183-190
    • (1996) Bioessays , vol.18 , pp. 183-190
    • Kearsey, S.E.1    Maiorano, D.2    Holmes, E.C.3
  • 57
    • 0035012849 scopus 로고    scopus 로고
    • Initiating DNA synthesis: From recruiting to activating the MCM complex
    • Lei M, Tye BK. Initiating DNA synthesis: from recruiting to activating the MCM complex. J Cell Sci 2001; 114:1447-1454
    • (2001) J Cell Sci , vol.114 , pp. 1447-1454
    • Lei, M.1    Tye, B.K.2
  • 58
    • 0034595448 scopus 로고    scopus 로고
    • Uninterrupted MCM2-7 function required for DNA replication fork progression
    • Labib K, Tercero JA, Diffley JF. Uninterrupted MCM2-7 function required for DNA replication fork progression. Science 2000; 288:1643-1647
    • (2000) Science , vol.288 , pp. 1643-1647
    • Labib, K.1    Tercero, J.A.2    Diffley, J.F.3
  • 59
    • 0027055823 scopus 로고
    • Localized deficiencies of folic acid in aerodigestive tissues
    • discussion 95-86
    • Heimburger DC. Localized deficiencies of folic acid in aerodigestive tissues. Ann NY Acad Sci 1992; 669:87-95; discussion 95-86
    • (1992) Ann NY Acad Sci , vol.669 , pp. 87-95
    • Heimburger, D.C.1
  • 60
    • 0023906360 scopus 로고
    • Improvement in bronchial squamous metaplasia in smokers treated with folate and vitamin B12: Report of a preliminary randomized, double-blind intervention trial
    • Heimburger DC, Alexander CB, Birch R, et al. Improvement in bronchial squamous metaplasia in smokers treated with folate and vitamin B12: report of a preliminary randomized, double-blind intervention trial. JAMA 1988; 259:1525-1530
    • (1988) JAMA , vol.259 , pp. 1525-1530
    • Heimburger, D.C.1    Alexander, C.B.2    Birch, R.3
  • 61
    • 0033791318 scopus 로고    scopus 로고
    • Cyclooxygenases: Structural, cellular, and molecular biology
    • Smith WL, DeWitt DL, Garavito RM. Cyclooxygenases: structural, cellular, and molecular biology. Annu Rev Biochern 2000; 69:145-182
    • (2000) Annu Rev Biochern , vol.69 , pp. 145-182
    • Smith, W.L.1    DeWitt, D.L.2    Garavito, R.M.3
  • 62
    • 0029783253 scopus 로고    scopus 로고
    • Transcription of cyclooxygenase-2 is enhanced in transformed mammary epithelial cells
    • Subbaramaiah K, Telang N, Ramonetti JT, et al. Transcription of cyclooxygenase-2 is enhanced in transformed mammary epithelial cells. Cancer Res 1996; 56:4424-4429
    • (1996) Cancer Res , vol.56 , pp. 4424-4429
    • Subbaramaiah, K.1    Telang, N.2    Ramonetti, J.T.3
  • 63
    • 0037083634 scopus 로고    scopus 로고
    • Expression of cyclooxygenase-1 and cyclooxygenase-2 in bronchial epithelium and nonsmall cell lung carcinoma
    • Hasturk S, Kemp B, Kalapurakal SK, et al. Expression of cyclooxygenase-1 and cyclooxygenase-2 in bronchial epithelium and nonsmall cell lung carcinoma. Cancer 2002; 94:1023-1031
    • (2002) Cancer , vol.94 , pp. 1023-1031
    • Hasturk, S.1    Kemp, B.2    Kalapurakal, S.K.3
  • 64
    • 0034901568 scopus 로고    scopus 로고
    • Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer
    • Khuri FR, Wu H, Lee JJ, et al. Cyclooxygenase-2 overexpression is a marker of poor prognosis in stage I non-small cell lung cancer. Clin Cancer Res 2001; 7:861-867
    • (2001) Clin Cancer Res , vol.7 , pp. 861-867
    • Khuri, F.R.1    Wu, H.2    Lee, J.J.3
  • 65
    • 0000218301 scopus 로고    scopus 로고
    • Cyclooxygenase-2 (COX-2) overexpression by immunohistochemistry (IHC) is associated with more aggressive biological behavior of non-small cell lung cancer (NSCLC) tumors
    • West HY, Giarrita S, Livingston R, et al. Cyclooxygenase-2 (COX-2) overexpression by immunohistochemistry (IHC) is associated with more aggressive biological behavior of non-small cell lung cancer (NSCLC) tumors. Proc Am Soc Clin Oncol 2002; 21:1235a
    • (2002) Proc Am Soc Clin Oncol , vol.21
    • West, H.Y.1    Giarrita, S.2    Livingston, R.3
  • 66
    • 0034161878 scopus 로고    scopus 로고
    • Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors
    • Masferrer JL, Leahy KM, Koki AT, et al. Antiangiogenic and antitumor activities of cyclooxygenase-2 inhibitors. Cancer Res 2000; 60:1306-1311
    • (2000) Cancer Res , vol.60 , pp. 1306-1311
    • Masferrer, J.L.1    Leahy, K.M.2    Koki, A.T.3
  • 67
    • 0030689046 scopus 로고    scopus 로고
    • The role of CXC chemokines in the regulation of angiogenesis in non-small cell lung cancer
    • Arenberg DA, Polverini PJ, Kunkel SL, et al. The role of CXC chemokines in the regulation of angiogenesis in non-small cell lung cancer. J Leukoc Biol 1997; 62:554-562
    • (1997) J Leukoc Biol , vol.62 , pp. 554-562
    • Arenberg, D.A.1    Polverini, P.J.2    Kunkel, S.L.3
  • 68
    • 17744406409 scopus 로고    scopus 로고
    • Epithelial-neutrophil activating peptide (ENA-78) is an important angiogenic factor in non-small cell lung cancer
    • Arenberg DA, Keane MP, DiGiovine B, et al. Epithelial-neutrophil activating peptide (ENA-78) is an important angiogenic factor in non-small cell lung cancer. J Clin Invest 1998; 102:465-472
    • (1998) J Clin Invest , vol.102 , pp. 465-472
    • Arenberg, D.A.1    Keane, M.P.2    DiGiovine, B.3
  • 69
    • 0037314803 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor and CXC chemokine expression in non-small cell lung cancer: Role in angiogenesis and prognosis
    • White ES, Flaherty KR, Carskadon S, et al. Macrophage migration inhibitory factor and CXC chemokine expression in non-small cell lung cancer: role in angiogenesis and prognosis. Clin Cancer Res 2003; 9:853-860
    • (2003) Clin Cancer Res , vol.9 , pp. 853-860
    • White, E.S.1    Flaherty, K.R.2    Carskadon, S.3
  • 70
    • 0346368096 scopus 로고    scopus 로고
    • Targeting cyclooxygenase-2 in human neoplasia: Rationale and promise
    • Dannenberg AJ, Subbaramaiah K. Targeting cyclooxygenase-2 in human neoplasia: rationale and promise. Cancer Cell 2003; 4:431-436
    • (2003) Cancer Cell , vol.4 , pp. 431-436
    • Dannenberg, A.J.1    Subbaramaiah, K.2
  • 71
    • 18544388537 scopus 로고    scopus 로고
    • Total cyclooxygenase-2 mRNA levels correlate with vascular endothelial growth factor mRNA levels, tumor angiogenesis and prognosis in non-small cell lung cancer patients
    • Yuan A, Yu CJ, Shun CT, et al. Total cyclooxygenase-2 mRNA levels correlate with vascular endothelial growth factor mRNA levels, tumor angiogenesis and prognosis in non-small cell lung cancer patients. Int J Cancer 2005; 115:545-555
    • (2005) Int J Cancer , vol.115 , pp. 545-555
    • Yuan, A.1    Yu, C.J.2    Shun, C.T.3
  • 72
    • 0032926177 scopus 로고    scopus 로고
    • Localization of matrix metalloproteinase 9 to the cell surface provides a mechanism for CD44-mediated tumor invasion
    • Yu Q, Stamenkovic I. Localization of matrix metalloproteinase 9 to the cell surface provides a mechanism for CD44-mediated tumor invasion. Genes Dev 1999; 13:35-48
    • (1999) Genes Dev , vol.13 , pp. 35-48
    • Yu, Q.1    Stamenkovic, I.2
  • 73
    • 0035877634 scopus 로고    scopus 로고
    • Non-small cell lung cancer cyclooxygenase-2-dependent invasion is mediated by CD44
    • Dohadwala M, Luo J, Zhu L, et al. Non-small cell lung cancer cyclooxygenase-2-dependent invasion is mediated by CD44. J Biol Chem 2001; 276:20809-20812
    • (2001) J Biol Chem , vol.276 , pp. 20809-20812
    • Dohadwala, M.1    Luo, J.2    Zhu, L.3
  • 74
    • 0346736504 scopus 로고    scopus 로고
    • Autocrine/paracrine prostaglandin E2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasion
    • Dohadwala M, Batra RK, Luo J, et al. Autocrine/paracrine prostaglandin E2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasion. J Biol Chem 2002; 277:50828-50833
    • (2002) J Biol Chem , vol.277 , pp. 50828-50833
    • Dohadwala, M.1    Batra, R.K.2    Luo, J.3
  • 75
    • 0026027556 scopus 로고
    • Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation
    • Liotta LA, Steeg PS, Stetler-Stevenson WG. Cancer metastasis and angiogenesis: an imbalance of positive and negative regulation. Cell 1991; 64:327-336
    • (1991) Cell , vol.64 , pp. 327-336
    • Liotta, L.A.1    Steeg, P.S.2    Stetler-Stevenson, W.G.3
  • 76
    • 0027333411 scopus 로고
    • Tumor cell interactions with the extracellular matrix during invasion and metastasis
    • Stetler-Stevenson WG, Aznavoorian S, Liotta LA. Tumor cell interactions with the extracellular matrix during invasion and metastasis. Annu Rev Cell Biol 1993; 9:541-573
    • (1993) Annu Rev Cell Biol , vol.9 , pp. 541-573
    • Stetler-Stevenson, W.G.1    Aznavoorian, S.2    Liotta, L.A.3
  • 77
    • 0028291737 scopus 로고
    • A matrix metalloproteinase expressed on the surface of invasive tumour cells
    • Sato H, Takino T, Okada Y, et al. A matrix metalloproteinase expressed on the surface of invasive tumour cells. Nature 1994; 370:61-65
    • (1994) Nature , vol.370 , pp. 61-65
    • Sato, H.1    Takino, T.2    Okada, Y.3
  • 78
    • 4644337725 scopus 로고    scopus 로고
    • Cyclooxygenase 2-dependent expression of survivin is critical for apoptosis resistance in non-small cell lung cancer
    • Krysan K, Dalwadi H, Sharma S, et al. Cyclooxygenase 2-dependent expression of survivin is critical for apoptosis resistance in non-small cell lung cancer. Cancer Res 2004; 64:6359-6362
    • (2004) Cancer Res , vol.64 , pp. 6359-6362
    • Krysan, K.1    Dalwadi, H.2    Sharma, S.3
  • 79
    • 1342310807 scopus 로고    scopus 로고
    • COX-2-dependent stabilization of survivin in non-small cell lung cancer
    • Krysan K, Merchant FH, Zhu L, et al. COX-2-dependent stabilization of survivin in non-small cell lung cancer. FASEB J 2004; 18:206-208
    • (2004) FASEB J , vol.18 , pp. 206-208
    • Krysan, K.1    Merchant, F.H.2    Zhu, L.3
  • 80
    • 0034097566 scopus 로고    scopus 로고
    • Role of insulin-like growth factors and their binding proteins in growth control and carcinogenesis
    • Grimberg A, Cohen P. Role of insulin-like growth factors and their binding proteins in growth control and carcinogenesis. J Cell Physiol 2000; 183:1-9
    • (2000) J Cell Physiol , vol.183 , pp. 1-9
    • Grimberg, A.1    Cohen, P.2
  • 81
    • 0034967343 scopus 로고    scopus 로고
    • Baxter RC. Signalling pathways involved in antiproliferative effects of IGFBP-3: a review. MoI Pathol 2001; 54:145-148
    • Baxter RC. Signalling pathways involved in antiproliferative effects of IGFBP-3: a review. MoI Pathol 2001; 54:145-148
  • 82
    • 0037329230 scopus 로고    scopus 로고
    • Rapid insulin-like growth factor (IGF)-independent effects of IGF binding protein-3 on endothelial cell survival
    • Franklin SL, Ferry RJ Jr, Cohen P. Rapid insulin-like growth factor (IGF)-independent effects of IGF binding protein-3 on endothelial cell survival. J Clin Endocrinol Metab 2003; 88:900-907
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 900-907
    • Franklin, S.L.1    Ferry Jr, R.J.2    Cohen, P.3
  • 83
    • 0026000892 scopus 로고
    • Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression
    • de Waal Malefyt R, Haanen J, Spits H, et al. Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression. J Exp Med 1991; 174:915-924
    • (1991) J Exp Med , vol.174 , pp. 915-924
    • de Waal Malefyt, R.1    Haanen, J.2    Spits, H.3
  • 84
    • 43949163341 scopus 로고
    • Interleukin-12 and its role in the generation of TH1 cells
    • Trinchieri G. Interleukin-12 and its role in the generation of TH1 cells, Immunol Today 1993; 14:335-338
    • (1993) Immunol Today , vol.14 , pp. 335-338
    • Trinchieri, G.1
  • 85
    • 0027963161 scopus 로고
    • Recombinant IL-12 administration induces tumor regression in association with IFN-gamma production
    • Nastala CL, Edington HD, McKinney TG, et al. Recombinant IL-12 administration induces tumor regression in association with IFN-gamma production. J Immunol 1994; 153:1697-1706
    • (1994) J Immunol , vol.153 , pp. 1697-1706
    • Nastala, C.L.1    Edington, H.D.2    McKinney, T.G.3
  • 86
    • 0028833639 scopus 로고
    • IL-10 inhibits tumor antigen presentation by epidermal antigen-presenting cells
    • Beissert S, Hosoi J, Grabbe S, et al. IL-10 inhibits tumor antigen presentation by epidermal antigen-presenting cells. J Immunol 1995; 154:1280-1286
    • (1995) J Immunol , vol.154 , pp. 1280-1286
    • Beissert, S.1    Hosoi, J.2    Grabbe, S.3
  • 87
    • 0032521401 scopus 로고    scopus 로고
    • Non-small cell lung cancer cyclooxygenase-2-dependent regulation of cytokine balance in lymphocytes and macrophages: Up-regulation of interleukin 10 and down-regulation of interleukin 12 production
    • Huang M, Stolina M, Sharma S, et al. Non-small cell lung cancer cyclooxygenase-2-dependent regulation of cytokine balance in lymphocytes and macrophages: up-regulation of interleukin 10 and down-regulation of interleukin 12 production. Cancer Res 1998; 58:1208-1216
    • (1998) Cancer Res , vol.58 , pp. 1208-1216
    • Huang, M.1    Stolina, M.2    Sharma, S.3
  • 88
    • 0033979545 scopus 로고    scopus 로고
    • Specific inhibition of cyclooxygenase 2 restores antitumor reactivity by altering the balance of IL-10 and IL-12 synthesis
    • Stolina M, Sharma S, Lin Y, et al. Specific inhibition of cyclooxygenase 2 restores antitumor reactivity by altering the balance of IL-10 and IL-12 synthesis. J Immunol 2000; 164:361-370
    • (2000) J Immunol , vol.164 , pp. 361-370
    • Stolina, M.1    Sharma, S.2    Lin, Y.3
  • 89
    • 0036799842 scopus 로고    scopus 로고
    • Celecoxib reduces pulmonary inflammation but not lung tumorigenesis in mice
    • Kisley LR, Barrett BS, Dwyer-Nield LD, et al. Celecoxib reduces pulmonary inflammation but not lung tumorigenesis in mice. Carcinogenesis 2002; 23:1653-1660
    • (2002) Carcinogenesis , vol.23 , pp. 1653-1660
    • Kisley, L.R.1    Barrett, B.S.2    Dwyer-Nield, L.D.3
  • 90
    • 6044256286 scopus 로고    scopus 로고
    • Modulation of pulmonary leukotriene B4 production by cyclooxygenase-2 inhibitors and lipopolysaccharide
    • Mao JT, Tsu IH, Dubinett SM, et al. Modulation of pulmonary leukotriene B4 production by cyclooxygenase-2 inhibitors and lipopolysaccharide. Clin Cancer Res 2004; 10:6872-6878
    • (2004) Clin Cancer Res , vol.10 , pp. 6872-6878
    • Mao, J.T.1    Tsu, I.H.2    Dubinett, S.M.3
  • 91
    • 0030023776 scopus 로고    scopus 로고
    • Growth control of lung cancer by interruption of 5-lipoxygenase-mediated growth factor signaling
    • Avis IM, Jett M, Boyle T, et al. Growth control of lung cancer by interruption of 5-lipoxygenase-mediated growth factor signaling, J Clin Invest 1996; 97:806-813
    • (1996) J Clin Invest , vol.97 , pp. 806-813
    • Avis, I.M.1    Jett, M.2    Boyle, T.3
  • 92
    • 0031705797 scopus 로고    scopus 로고
    • Inhibitors of lipoxygenase: A new class of cancer chemopreventive agents
    • Rioux N, Castonguay A. Inhibitors of lipoxygenase: a new class of cancer chemopreventive agents. Carcinogenesis 1998; 19:1393-1400
    • (1998) Carcinogenesis , vol.19 , pp. 1393-1400
    • Rioux, N.1    Castonguay, A.2
  • 93
    • 0242611540 scopus 로고    scopus 로고
    • Cyclooxygenase-2 and 5-lipoxygenase converging functions on cell proliferation and tumor angiogenesis: Implications for cancer therapy
    • Romano M, Claria J. Cyclooxygenase-2 and 5-lipoxygenase converging functions on cell proliferation and tumor angiogenesis: implications for cancer therapy. FASEB J 2003; 17:1986-1995
    • (2003) FASEB J , vol.17 , pp. 1986-1995
    • Romano, M.1    Claria, J.2
  • 94
    • 5144228550 scopus 로고    scopus 로고
    • A randomized phase lib trial of Pulmicort Turbuhaler (budesonide) in people with dysplasia of the bronchial epithelium
    • Lam S, leRiche JC, McWilliams A, et al, A randomized phase lib trial of Pulmicort Turbuhaler (budesonide) in people with dysplasia of the bronchial epithelium. Clin Cancer Res 2004; 10:6502-6511
    • (2004) Clin Cancer Res , vol.10 , pp. 6502-6511
    • Lam, S.1    leRiche, J.C.2    McWilliams, A.3
  • 95
    • 0346734287 scopus 로고    scopus 로고
    • Celecoxib modulates the capacity for prostaglandin E2 and interleukin-10 production in alveolar macrophages from active smokers
    • Mao JT, Roth MD, Serio KJ, et al. Celecoxib modulates the capacity for prostaglandin E2 and interleukin-10 production in alveolar macrophages from active smokers. Clin Cancer Res 2003; 9:5835-5841
    • (2003) Clin Cancer Res , vol.9 , pp. 5835-5841
    • Mao, J.T.1    Roth, M.D.2    Serio, K.J.3
  • 96
    • 31544467105 scopus 로고    scopus 로고
    • Celecoxib decreases Ki-67 proliferative index in active smokers
    • Mao JT, Fishbein MC, Adams B, et al. Celecoxib decreases Ki-67 proliferative index in active smokers, Clin Cancer Res 2006; 12:314-320
    • (2006) Clin Cancer Res , vol.12 , pp. 314-320
    • Mao, J.T.1    Fishbein, M.C.2    Adams, B.3
  • 97
    • 0034707105 scopus 로고    scopus 로고
    • Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis: VIGOR Study Group
    • Bombardier C, Laine L, Reicin A, et al. Comparison of upper gastrointestinal toxicity of rofecoxib and naproxen in patients with rheumatoid arthritis: VIGOR Study Group. N Engl J Med 2000; 343:1520-1528
    • (2000) N Engl J Med , vol.343 , pp. 1520-1528
    • Bombardier, C.1    Laine, L.2    Reicin, A.3
  • 98
    • 0034644396 scopus 로고    scopus 로고
    • Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: The CLASS study; a randomized controlled trial; Celecoxib Long-term Arthritis Safety Study
    • Silverstein FE, Faich G, Goldstein JL, et al. Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study; a randomized controlled trial; Celecoxib Long-term Arthritis Safety Study. JAMA 2000; 284:1247-1255
    • (2000) JAMA , vol.284 , pp. 1247-1255
    • Silverstein, F.E.1    Faich, G.2    Goldstein, J.L.3
  • 99
    • 19744380776 scopus 로고    scopus 로고
    • Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial
    • Bresalier RS, Sandler RS, Quan H, et al. Cardiovascular events associated with rofecoxib in a colorectal adenoma chemoprevention trial. N Engl J Med 2005; 352:1092-1102
    • (2005) N Engl J Med , vol.352 , pp. 1092-1102
    • Bresalier, R.S.1    Sandler, R.S.2    Quan, H.3
  • 100
    • 20144365496 scopus 로고    scopus 로고
    • Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention
    • Solomon SD, McMurray JJ, Pfeffer MA, et al. Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention. N Engl J Med 2005; 352:1071-1080
    • (2005) N Engl J Med , vol.352 , pp. 1071-1080
    • Solomon, S.D.1    McMurray, J.J.2    Pfeffer, M.A.3
  • 101
    • 2942610569 scopus 로고    scopus 로고
    • Selenium and lung cancer: A quantitative analysis of heterogeneity in the current epidemiological literature
    • Zhuo H, Smith AH, Steinmaus C. Selenium and lung cancer: a quantitative analysis of heterogeneity in the current epidemiological literature. Cancer Epidemiol Biomarkers Prev 2004; 13:771-778
    • (2004) Cancer Epidemiol Biomarkers Prev , vol.13 , pp. 771-778
    • Zhuo, H.1    Smith, A.H.2    Steinmaus, C.3
  • 102
    • 0027363891 scopus 로고
    • A prospective cohort study on selenium status and the risk of lung cancer
    • van den Brandt PA, Goldbohm RA, van't Veer P, et al. A prospective cohort study on selenium status and the risk of lung cancer. Cancer Res 1993; 53:4860-4865
    • (1993) Cancer Res , vol.53 , pp. 4860-4865
    • van den Brandt, P.A.1    Goldbohm, R.A.2    van't Veer, P.3
  • 103
    • 13744264090 scopus 로고    scopus 로고
    • Designing the Selenium and Vitamin E Cancer Prevention Trial (SELECT)
    • Lippman SM, Goodman PJ, Klein EA, et al. Designing the Selenium and Vitamin E Cancer Prevention Trial (SELECT). J Natl Cancer Inst 2005; 97:94-102
    • (2005) J Natl Cancer Inst , vol.97 , pp. 94-102
    • Lippman, S.M.1    Goodman, P.J.2    Klein, E.A.3
  • 104
    • 1242295294 scopus 로고    scopus 로고
    • Rapid induction of apoptosis in prostate cancer cells by selenium: Reversal by metabolites of arachidonate 5-lipoxygenase
    • Ghosh J. Rapid induction of apoptosis in prostate cancer cells by selenium: reversal by metabolites of arachidonate 5-lipoxygenase. Biochem Biophys Res Commun 2004; 315:624-635
    • (2004) Biochem Biophys Res Commun , vol.315 , pp. 624-635
    • Ghosh, J.1
  • 105
    • 0036846660 scopus 로고    scopus 로고
    • Selenium supplementation and lung cancer incidence: An update of the Nutritional Prevention of Cancer Trial
    • Reid ME, Duffield-Lillico AJ, Garland L, et al. Selenium supplementation and lung cancer incidence: an update of the Nutritional Prevention of Cancer Trial. Cancer Epidemiol Biomarkers Prev 2002; 11:1285-1291
    • (2002) Cancer Epidemiol Biomarkers Prev , vol.11 , pp. 1285-1291
    • Reid, M.E.1    Duffield-Lillico, A.J.2    Garland, L.3
  • 107
    • 34848836897 scopus 로고    scopus 로고
    • Phase 1 chemoprevention trial of oltipraz in smokers [abstract]
    • Kelley M, Folz RJ, Glaser EM, et al. Phase 1 chemoprevention trial of oltipraz in smokers [abstract]. Proc Am Soc Clin Oncol 2003; 22:92
    • (2003) Proc Am Soc Clin Oncol , vol.22 , pp. 92
    • Kelley, M.1    Folz, R.J.2    Glaser, E.M.3
  • 108
    • 0035730760 scopus 로고    scopus 로고
    • Phase I/pharmacodynamic study of N-acetylcysteine/oltipraz in smokers: Early termination due to excessive toxicity
    • Pendyala L, Schwartz G, Bolanowska-Higdon W, et al. Phase I/pharmacodynamic study of N-acetylcysteine/oltipraz in smokers: early termination due to excessive toxicity, Cancer Epidemiol Biomarkers Prev 2001; 10:269-272
    • (2001) Cancer Epidemiol Biomarkers Prev , vol.10 , pp. 269-272
    • Pendyala, L.1    Schwartz, G.2    Bolanowska-Higdon, W.3
  • 109
    • 0037014797 scopus 로고    scopus 로고
    • A randomized phase IIb trial of anethole dithiolethione in smokers with bronchial dysplasia
    • Lam S, MacAulay C, Le Riche JC, et al. A randomized phase IIb trial of anethole dithiolethione in smokers with bronchial dysplasia. J Natl Cancer Inst 2002; 94:1001-1009
    • (2002) J Natl Cancer Inst , vol.94 , pp. 1001-1009
    • Lam, S.1    MacAulay, C.2    Le Riche, J.C.3
  • 110
    • 0033386539 scopus 로고    scopus 로고
    • Protein kinase C targeting in antineoplastic treatment strategies
    • Jarvis WD, Grant S. Protein kinase C targeting in antineoplastic treatment strategies, Invest New Drugs 1999; 17:227-240
    • (1999) Invest New Drugs , vol.17 , pp. 227-240
    • Jarvis, W.D.1    Grant, S.2
  • 111
    • 0032213794 scopus 로고    scopus 로고
    • Analogs of staurosporine: Potential anticancer drugs?
    • Gescher A. Analogs of staurosporine: potential anticancer drugs? Gen Pharmacol 1998; 31:721-728
    • (1998) Gen Pharmacol , vol.31 , pp. 721-728
    • Gescher, A.1
  • 112
    • 0032987224 scopus 로고    scopus 로고
    • Inhibition of protein kinase C: Do we, can we, and should we?
    • Parker PJ. Inhibition of protein kinase C: do we, can we, and should we? Pharmacol Ther 1999; 82:263-267
    • (1999) Pharmacol Ther , vol.82 , pp. 263-267
    • Parker, P.J.1
  • 113
    • 0033959438 scopus 로고    scopus 로고
    • Effect of farnesyltransferase inhibitor FTI-276 on established lung adenomas from A/J mice induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
    • Lantry LE, Zhang Z, Yao R, et al. Effect of farnesyltransferase inhibitor FTI-276 on established lung adenomas from A/J mice induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone. Carcinogenesis 2000; 21:113-116
    • (2000) Carcinogenesis , vol.21 , pp. 113-116
    • Lantry, L.E.1    Zhang, Z.2    Yao, R.3
  • 114
    • 0142088857 scopus 로고    scopus 로고
    • Farnesyltransferase inhibitors are potent lung cancer chemopreventive agents in A/J mice with a dominant-negative p53 and/or heterozygous deletion of Ink4a/Arf
    • Zhang Z, Wang Y, Lantry LE, et al. Farnesyltransferase inhibitors are potent lung cancer chemopreventive agents in A/J mice with a dominant-negative p53 and/or heterozygous deletion of Ink4a/Arf Oncogene 2003; 22:6257-6265
    • (2003) Oncogene , vol.22 , pp. 6257-6265
    • Zhang, Z.1    Wang, Y.2    Lantry, L.E.3
  • 115
    • 0037989766 scopus 로고    scopus 로고
    • Chemoprevention of benzo (a) pyrene-induced lung tumors in mice by the farnesyltransferase inhibitor R115777
    • Gunning WT, Kramer PM, Lubet RA, et al. Chemoprevention of benzo (a) pyrene-induced lung tumors in mice by the farnesyltransferase inhibitor R115777. Clin Cancer Res 2003; 9:1927-1930
    • (2003) Clin Cancer Res , vol.9 , pp. 1927-1930
    • Gunning, W.T.1    Kramer, P.M.2    Lubet, R.A.3
  • 116
    • 0020396781 scopus 로고
    • Correlation between precancerous bronchial metaplasia and cigarette consumption, and preliminary results of retinoid treatment
    • Mathe G, Gouveia J, Hercend T, et al. Correlation between precancerous bronchial metaplasia and cigarette consumption, and preliminary results of retinoid treatment. Cancer Detect Prev 1982; 5:461-466
    • (1982) Cancer Detect Prev , vol.5 , pp. 461-466
    • Mathe, G.1    Gouveia, J.2    Hercend, T.3
  • 117
    • 0026561819 scopus 로고
    • The effect of the synthetic retinoid etretinate on sputum cytology: Results from a randomised trial
    • Arnold AM, Browman GP, Levine MN, et al. The effect of the synthetic retinoid etretinate on sputum cytology: results from a randomised trial. Br J Cancer 1992; 65:737-743
    • (1992) Br J Cancer , vol.65 , pp. 737-743
    • Arnold, A.M.1    Browman, G.P.2    Levine, M.N.3
  • 119
    • 0028280222 scopus 로고
    • Randomized placebo-controlled trial of isotretinoin in chemoprevention of bronchial squamous metaplasia
    • Lee JS, Lippman SM, Benner SE, et al. Randomized placebo-controlled trial of isotretinoin in chemoprevention of bronchial squamous metaplasia. J Clin Oncol 1994; 12:937-945
    • (1994) J Clin Oncol , vol.12 , pp. 937-945
    • Lee, J.S.1    Lippman, S.M.2    Benner, S.E.3
  • 120
    • 0033875561 scopus 로고    scopus 로고
    • N-(4-hydroxyphenyl)-retinamide in the chemoprevention of squamous metaplasia and dysplasia of the bronchial epithelium
    • Kurie JM, Lee JS, Khuri FR, et al. N-(4-hydroxyphenyl)-retinamide in the chemoprevention of squamous metaplasia and dysplasia of the bronchial epithelium. Clin Cancer Res 2000; 6:2973-2979
    • (2000) Clin Cancer Res , vol.6 , pp. 2973-2979
    • Kurie, J.M.1    Lee, J.S.2    Khuri, F.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.