Inhibition of gamma-secretase activity promotes differentiation of embryonic pancreatic precursor cells into functional islet-like clusters in poly(ethylene glycol) hydrogel culture

Tissue Engineering - Part A

Volumn 16, Issue 8, 2010, Pages 2593-2603

  Mason, Mariah N ^a   Mahoney, Melissa J ^a  

^a UCB 450   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGGREGATES; CELLS; ETHYLENE; ETHYLENE GLYCOL; GENE EXPRESSION; GLUCOSE; HYDROGELS; INSULIN; PEPTIDES; POLYETHYLENE GLYCOLS; POLYETHYLENE OXIDES;

BETA CELL; COLLAGEN TYPE 1; CONTROL MEDIUMS; IN-VITRO; INSULIN RELEASE; NOTCH SIGNALING; PEPTIDE RELEASE; POLY(ETHYLENE GLYCOL) HYDROGEL; PRECURSOR CELLS; PROINSULIN; RAT EMBRYO; RAT ISLETS; SECRETASES; SINGLE CELLS;

CELL CULTURE;

RATTUS;

MACROGOL DERIVATIVE; SECRETASE;

ANIMAL; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL ENLARGEMENT; CELL SURVIVAL; CHEMISTRY; CULTURE TECHNIQUE; CYTOLOGY; DRUG ANTAGONISM; EMBRYONIC STEM CELL; ENZYMOLOGY; GEOGRAPHY; METHODOLOGY; PANCREAS ISLET; PHYSIOLOGY; RAT; SPRAGUE DAWLEY RAT; TISSUE ENGINEERING;

AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL ENLARGEMENT; CELL SURVIVAL; CELLS, CULTURED; EMBRYONIC STEM CELLS; GEOGRAPHY; ISLETS OF LANGERHANS; POLYETHYLENE GLYCOLS; RATS; RATS, SPRAGUE-DAWLEY; TISSUE ENGINEERING;

EID: 77956072108     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2010.0015     Document Type: Article

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