Maintaining high anaerobic succinic acid productivity by product removal

Bioprocess and Biosystems Engineering

Volumn 33, Issue 6, 2010, Pages 711-718

  Andersson, Christian ^a   Petrova, Ekaterina ^a   Berglund, Kris ^a,b   Rova, Ulrika ^a  

^a LULEÅ UNIVERSITY OF TECHNOLOGY   (Sweden)

^b MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

Cell resuspension; Cell viability; Fermentation; Productivity; Succinic acid

Indexed keywords

BY-PRODUCT REMOVAL; CELL VIABILITY; FERMENTATION KINETICS; RE-SUSPENSION; SUCCINIC ACIDS; VIABLE CELLS; VOLUMETRIC PRODUCTIVITY;

ACIDS; CYTOLOGY; ESCHERICHIA COLI; FERMENTATION; PRODUCTIVITY;

CELLS;

SUCCINIC ACID; CULTURE MEDIUM;

ANAEROBIC CAPACITY; ARTICLE; BACTERIAL VIABILITY; BATCH FERMENTATION; CELL SUSPENSION; CONCENTRATION RESPONSE; CONTROLLED STUDY; ESCHERICHIA COLI; FERMENTATION MEDIUM; GENETIC ENGINEERING; NONHUMAN; PRIORITY JOURNAL; PRODUCTIVITY; ANAEROBIC GROWTH; CULTURE MEDIUM; ENZYMOLOGY; FERMENTATION; GROWTH, DEVELOPMENT AND AGING; ISOLATION AND PURIFICATION; KINETICS; METABOLISM; MICROBIOLOGICAL EXAMINATION; TIME;

ANAEROBIOSIS; BACTERIOLOGICAL TECHNIQUES; CULTURE MEDIA; ESCHERICHIA COLI; FERMENTATION; KINETICS; SUCCINIC ACID; TIME FACTORS;

ESCHERICHIA COLI;

EID: 77956061846     PISSN: 16157591     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00449-009-0393-y     Document Type: Article

References (31)

1. Werpy T, Petersen G (2004) Top value added chemicals from biomass, volume I. US Department of Energy, http://www1.eere.energy.gov/biomass/pdfs/35523.pdf
2. JG Zeikus MK Jain P Elankovan 1999 Biotechnology of succinic acid production and markets for derived industrial products Appl Microbiol Biotechnol 51 545 552 10.1007/s002530051431 1:CAS:528:DyaK1MXkt1yqs78%3D (Pubitemid 29266304)
3. R Chatterjee CS Millard K Champion DP Clark MI Donnelly 2001 Mutation of the ptsG gene results in increased production of succinate in fermentation of glucose by Escherichia coli Appl Environ Microbiol 67 148 154 10.1128/AEM.67.1.148-154.2001 1:CAS:528:DC%2BD3MXjtVWgsw%3D%3D (Pubitemid 32044412)
4. H Lin GN Bennett KY San 2005 Fed-batch culture of a metabolically engineered Escherichia coli strain designed for high-level succinate production and yield under aerobic conditions Biotechnol Bioeng 90 775 779 10.1002/bit.20458 1:CAS:528:DC%2BD2MXkvFGgtb8%3D (Pubitemid 40744245)
5. NS Samuelov R Datta MK Jain JG Zeikus 1999 Whey fermentation by Anaerobiospirillum succiniciproducens for production of a succinate-based animal feed additive Appl Environ Microbiol 65 2260 2263 1:CAS:528:DyaK1MXjtVamt7Y%3D
6. DY Kim SC Yim PC Lee WG Lee SY Lee HN Chang 2004 Batch and continuous fermentation of succinic acid from wood hydrolysate by Mannheimia succiniciproducens MBEL55E Enzyme Microb Technol 35 648 653 10.1016/j.enzmictec. 2004.08.018 1:CAS:528:DC%2BD2cXptFOqt7w%3D (Pubitemid 39452727)
7. L Agarwal J Isar GK Meghwanshi RK Saxena 2006 A cost effective fermentative production of succinic acid from cane molasses and corn steep liquor by Escherichia coli J Appl Microbiol 100 1348 1354 10.1111/j.1365-2672. 2006.02894.x 1:CAS:528:DC%2BD28XntVylt7c%3D (Pubitemid 43739185)
8. PC Lee SY Lee SH Hong HN Chang 2002 Isolation and characterization of a new succinic acid-producing bacterium, Mannheimia succiniciproducens MBEL55E, from bovine rumen Appl Microbiol Biotechnol 58 663 668 10.1007/s00253-002-0935-6 1:CAS:528:DC%2BD38Xjs12ktbk%3D (Pubitemid 34299232)
9. H Lin GN Bennett KY San 2005 Chemostat culture characterization of Escherichia coli mutant strains metabolically engineered for aerobic succinate production: a study of the modified metabolic network based on metabolite profile, enzyme activity, and gene expression profile Metab Eng 7 337 352 10.1016/j.ymben.2005.06.002 1:CAS:528:DC%2BD2MXhtlWktLfE (Pubitemid 41794052)
10. MI Donnelly CS Millard DP Clark MJ Chen JW Rathke 1998 A novel fermentation pathway in an Escherichia coli mutant producing succinic acid, acetic acid, and ethanol Appl Biochem Biotechnol 70-2 187 198 10.1007/BF02920135
11. K Jantama MJ Haupt SA Svoronos XL Zhang JC Moore KT Shanmugam LO Ingram 2008 Combining metabolic engineering and metabolic evolution to develop nonrecombinant strains of Escherichia coli C that produce succinate and malate Biotechnol Bioeng 99 1140 1153 10.1002/bit.21694 1:CAS:528:DC%2BD1cXjtlGksrc%3D (Pubitemid 351462773)
12. GN Vemuri MA Eiteman E Altman 2002 Effects of growth mode and pyruvate carboxylase on succinic acid production by metabolically engineered strains of Escherichia coli Appl Environ Microbiol 68 1715 1727 10.1128/AEM.68.4.1715-1727. 2002 1:CAS:528:DC%2BD38XivFGltLo%3D (Pubitemid 34284775)
13. C Andersson J Helmerius D Hodge KA Berglund U Rova 2009 Inhibition of succinic acid production in metabolically engineered Escherichia coli by neutralizing agent, organic acids, and osmolarity Biotechnol Prog 25 116 123 10.1002/btpr.127 1:CAS:528:DC%2BD1MXivFehsLs%3D
14. Warnecke T, Gill RT (2005) Organic acid toxicity, tolerance, and production in Escherichia coli biorefining applications. Microb Cell Fact 4:25
15. Yedur S, Berglund KA, Dunuwila DD (2001) Succinic acid production and purification. U.S. Patent 6,265,190
16. YS Huh YS Jun YK Hong H Song SY Lee WH Hong 2006 Effective purification of succinic acid from fermentation broth produced by Mannheimia succiniciproducens Process Biochemistry 41 1461 1465 10.1016/j.procbio.2006.01. 020 1:CAS:528:DC%2BD28XjvFSisrw%3D
17. K Schügerl 2000 Integrated processing of biotechnology products Biotechnol Adv 18 581 599 10.1016/S0734-9750(00)00051-3 (Pubitemid 32122511)
18. N Cao J Du CS Gong GT Tsao 1996 Simultaneous production and recovery of fumaric acid from immobilized Rhizopus oryzae with a rotary biofilm contactor and an adsorption column Appl Environ Microbiol 62 2926 2931 1:CAS:528:DyaK28Xkslemtro%3D
19. I Meynial-Salles S Dorotyn P Soucaille 2008 A new process for the continuous production of succinic acid from glucose at high yield, titer, and productivity Biotechnol Bioeng 99 129 135 10.1002/bit.21521 1:CAS:528: DC%2BD2sXhsVOrsLjI
20. M Sauer D Porro D Mattanovich P Branduardi 2008 Microbial production of organic acids: expanding the markets Trends Biotechnol 26 100 108 10.1016/j.tibtech.2007.11.006 1:CAS:528:DC%2BD1cXhsVCktL8%3D
21. C Andersson D Hodge KA Berglund U Rova 2007 Effect of different carbon sources on the production of succinic acid using metabolically engineered Escherichia coli Biotechnol Prog 23 381 388 10.1021/bp060301y 1:CAS:528:DC%2BD2sXot1aisw%3D%3D (Pubitemid 46626312)
22. Donnelly MI, Sanville-Millard CY, Nghiem NP (2004) Method to produce succinic acid from raw hydrolysates. U.S. Patent 6,743,610
23. GN Vemuri MA Eiteman E Altman 2002 Succinate production in dual-phase Escherichia coli fermentations depends on the time of transition from aerobic to anaerobic conditions J Ind Microbiol Biotechnol 28 325 332 10.1038/sj.jim. 7000250 1:CAS:528:DC%2BD38Xks12ltr8%3D
24. H Lin GN Bennett KY San 2005 Metabolic engineering of aerobic succinate production systems in Escherichia coli to improve process productivity and achieve the maximum theoretical succinate yield Metab Eng 7 116 127 10.1016/j.ymben.2004.10.003 1:CAS:528:DC%2BD2MXisVCmu7c%3D (Pubitemid 40392480)
25. SJ Lee H Song SY Lee 2006 Genome-based metabolic engineering of Mannheimia succiniciproducens for succinic acid production Appl Environ Microbiol 72 1939 1948 10.1128/AEM.72.3.1939-1948.2006 1:CAS:528: DC%2BD28XjsFCmsb8%3D
26. AM Sanchez GN Bennett KY San 2005 Novel pathway engineering design of the anaerobic central metabolic pathway in Escherichia coli to increase succinate yield and productivity Metab Eng 7 229 239 10.1016/j.ymben.2005.03.001 1:CAS:528:DC%2BD2MXktVKgur0%3D (Pubitemid 40703912)
27. JW Foster 2004 Escherichia coli acid resistance: tales of an amateur acidophile Nat Rev Microbiol 2 898 907 10.1038/nrmicro1021 1:CAS:528: DC%2BD2cXos1KqurY%3D (Pubitemid 39561806)
28. SKC Lin C Du A Koutinas R Wang C Webb 2008 Substrate and product inhibition kinetics in succinic acid production by Actinobacillus succinogenes Biochem Eng J 41 128 135 10.1016/j.bej.2008.03.013 1:CAS:528: DC%2BD1cXpsVagtL4%3D
29. RI Corona-González A Bories V González-Álvarez C Pelayo-Ortiz 2008 Kinetic study of succinic acid production by Actinobacillus succinogenes ZT-130 Process Biochem 42 1047 1053 10.1016/j.procbio.2008.05.011
30. AJA van Maris AA Winkler D Porro JP van Dijken JT Pronk 2004 Homofermentative lactate production cannot sustain anaerobic growth of engineered Saccharomyces cerevisiae: possible consequence of energy-dependent lactate export Appl Environ Microbiol 70 2898 2905 10.1128/AEM.70.5.2898-2905. 2004 (Pubitemid 38657807)
31. AJA van Maris WN Konings JP van Dijken JT Pronk 2004 Microbial export of lactic and 3-hydroxypropanoic acid: implications for industrial fermentation processes Metab Eng 6 245 255 10.1016/j.ymben.2004.05.001 (Pubitemid 39379460)