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Volumn 162, Issue 2, 2010, Pages 290-298

Impaired IL-4 phosphorylation of STAT6 in EBV transformed B-cells

Author keywords

B lymphocytes; Interferon gamma; Interleukin 4; STAT6

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 4; INTERLEUKIN 4 RECEPTOR; JANUS KINASE 1; JANUS KINASE 2; STAT6 PROTEIN;

EID: 77955981359     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2009.01.004     Document Type: Article
Times cited : (4)

References (34)
  • 1
    • 15844404509 scopus 로고    scopus 로고
    • Essential role of Stat6 in IL-4 signaling
    • Takeda K, Tanaka T, Shi W, et al. Essential role of Stat6 in IL-4 signaling. Nature 1996;380:627.
    • (1996) Nature , vol.380 , pp. 627
    • Takeda, K.1    Tanaka, T.2    Shi, W.3
  • 2
    • 0033010373 scopus 로고    scopus 로고
    • The IL-4 receptor: Signaling mechanisms and biologic functions
    • Nelms K, Keegan AS, Zamorano J, et al. The IL-4 receptor: Signaling mechanisms and biologic functions. Annu Rev Immunol 1999;17:701.
    • (1999) Annu. Rev. Immunol. , vol.17 , pp. 701
    • Nelms, K.1    Keegan, A.S.2    Zamorano, J.3
  • 5
    • 0037379876 scopus 로고    scopus 로고
    • Genetic control of Inter-leukin-4-induced activation of the human signal transducer and activator of transcription 6 signaling pathway
    • Zhang WJ, Koltun WA, Tilberg AF, et al. Genetic control of Inter-leukin-4-induced activation of the human signal transducer and activator of transcription 6 signaling pathway. Human Immunol 2003;64:402.
    • (2003) Human Immunol. , vol.64 , pp. 402
    • Zhang, W.J.1    Koltun, W.A.2    Tilberg, A.F.3
  • 10
    • 0011124007 scopus 로고
    • Up-regulation of Interleukin 4/B-Cell stimulatory factor 1 receptor expression
    • Ohara J, Paul WE. Up-regulation of Interleukin 4/B-Cell stimulatory factor 1 receptor expression. PNAS 1988;85:8221.
    • (1988) PNAS , vol.85 , pp. 8221
    • Ohara, J.1    Paul, W.E.2
  • 11
    • 0031561791 scopus 로고    scopus 로고
    • Comparison of IL-13-and IL-4-induced signaling in EBV-immortalized human B cells
    • Murata T, Puri RJ. Comparison of IL-13-and IL-4-induced signaling in EBV-immortalized human B cells. Cell Immunol 1997;175:33.
    • (1997) Cell. Immunol. , vol.175 , pp. 33
    • Murata, T.1    Puri, R.J.2
  • 12
    • 0037184088 scopus 로고    scopus 로고
    • Analysis of the life cycle of Stat6 continuous cycling of Stat6 is required for IL-4 signaling
    • Andrews RP, Ericksen MB, Cunningham CM, et al. Analysis of the life cycle of Stat6 continuous cycling of Stat6 is required for IL-4 signaling. J Biol Chem 2002;277:36563.
    • (2002) J. Biol. Chem. , vol.277 , pp. 36563
    • Andrews, R.P.1    Ericksen, M.B.2    Cunningham, C.M.3
  • 13
    • 33751203273 scopus 로고    scopus 로고
    • The Epstein-barr virus-encoded LMP-1 oncoprotein negatively affects Tyk2 phosphorylation and interferon signaling in human B cells
    • Geiger TR, Martin JM. The Epstein-Barr Virus-Encoded LMP-1 oncoprotein negatively affects Tyk2 phosphorylation and interferon signaling in human B cells. J Virol 2006;80:11838.
    • (2006) J. Virol. , vol.80 , pp. 11838
    • Geiger, T.R.1    Martin, J.M.2
  • 15
    • 0032850616 scopus 로고    scopus 로고
    • Interferons inhibit activation of Stat6 by interleukin 4 inhuman monocytes by inducing SOCS-1 gene expression
    • Dickensheets HL, Vengataraman C, Schindler U, et al. Interferons inhibit activation of Stat6 by interleukin 4 inhuman monocytes by inducing SOCS-1 gene expression. Proc Natl Acad Sci 1999;96:10800.
    • (1999) Proc. Natl. Acad. Sci. , vol.96 , pp. 10800
    • Dickensheets, H.L.1    Vengataraman, C.2    Schindler, U.3
  • 16
    • 0033120880 scopus 로고    scopus 로고
    • Cutting edge: SOCS-1 is a potent inhibitor of IL-4 signal transduction
    • Losman JA, Chen XP, Hilton D, et al. Cutting edge: SOCS-1 is a potent inhibitor of IL-4 signal transduction. J Immunol 1999;162:3770.
    • (1999) J. Immunol. , vol.162 , pp. 3770
    • Losman, J.A.1    Chen, X.P.2    Hilton, D.3
  • 17
    • 0030792590 scopus 로고    scopus 로고
    • A family of cytokine-inducible inhibitors of signaling
    • Starr R, Willson TA, Viney EM, et al. A family of cytokine-inducible inhibitors of signaling. Nature 1997;387:917.
    • (1997) Nature , vol.387 , pp. 917
    • Starr, R.1    Willson, T.A.2    Viney, E.M.3
  • 18
    • 0030839112 scopus 로고    scopus 로고
    • A new protein containing an SH2 domain that inhibits JAK kinases
    • Endo TA, Masuhara M, Yokouchi M, et al. A new protein containing an SH2 domain that inhibits JAK kinases. Nature 1997;387:921.
    • (1997) Nature , vol.387 , pp. 921
    • Endo, T.A.1    Masuhara, M.2    Yokouchi, M.3
  • 19
    • 1542493212 scopus 로고    scopus 로고
    • Negative regulation of cytokine signaling by CIS/SOCS family proteins and their roles in inflammatory diseases
    • Hanada T, Kinjyo I, Inagaki-Ohara K, et al. Negative regulation of cytokine signaling by CIS/SOCS family proteins and their roles in inflammatory diseases. Rev Physiol Biochem Pharmacol 2003;149:72.
    • (2003) Rev. Physiol. Biochem. Pharmacol. , vol.149 , pp. 72
    • Hanada, T.1    Kinjyo, I.2    Inagaki-Ohara, K.3
  • 21
    • 12444342977 scopus 로고    scopus 로고
    • γ suppresses STAT6 phosphorylation by inhibiting its recruitment to the IL-4 receptor
    • γ suppresses STAT6 phosphorylation by inhibiting its recruitment to the IL-4 receptor. J Immunol 2005;174:1332.
    • (2005) J. Immunol. , vol.174 , pp. 1332
    • Huang, Z.1    Xin, J.2    Coleman, J.3
  • 22
    • 0036790814 scopus 로고    scopus 로고
    • Expression of the suppressor of cytokine signaling-5 (SOCS5) negatively regulates IL-4-dependent STAT6 activation and Th2 differentiation
    • Seki Y, Hayashi K, Matsumoto A, et al. Expression of the suppressor of cytokine signaling-5 (SOCS5) negatively regulates IL-4-dependent STAT6 activation and Th2 differentiation. Proc Natl Acad Sci USA 2002;99:13003.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 13003
    • Seki, Y.1    Hayashi, K.2    Matsumoto, A.3
  • 23
    • 0032545279 scopus 로고    scopus 로고
    • Protein-tyrosine phosphatase Shp-1 is a negative regulator of IL-4-and IL-13-dependent signal transduction
    • Haque SJ, Harbor P, Tabrizi M, et al. Protein-tyrosine phosphatase Shp-1 is a negative regulator of IL-4-and IL-13-dependent signal transduction. J Biol Chem 1998;273:33893.
    • (1998) J. Biol. Chem. , vol.273 , pp. 33893
    • Haque, S.J.1    Harbor, P.2    Tabrizi, M.3
  • 24
    • 0027452977 scopus 로고
    • Disruptionofthe murine IL-4 blocks Th2 cytokine responses
    • Kopf M, Le Gros G, Bachmann M, et al. Disruptionofthe murine IL-4 blocks Th2 cytokine responses. Nature 1993;362:245.
    • (1993) Nature , vol.362 , pp. 245
    • Kopf, M.1    Le Gros, G.2    Bachmann, M.3
  • 25
    • 0024353079 scopus 로고
    • TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties
    • Mosmann TR, Coffman RL. TH1 and TH2 cells: Different patterns of lymphokine secretion lead to different functional properties. Ann Rev Immunol 1989;7:145.
    • (1989) Ann. Rev. Immunol. , vol.7 , pp. 145
    • Mosmann, T.R.1    Coffman, R.L.2
  • 27
    • 0023197097 scopus 로고
    • Interferon-gamma and B cell stimulatory factor-1 reciprocally regulate Ig isotype production
    • Snapper CM, Paul WE. Interferon-gamma and B cell stimulatory factor-1 reciprocally regulate Ig isotype production. Science 1987;236:944.
    • (1987) Science , vol.236 , pp. 944
    • Snapper, C.M.1    Paul, W.E.2
  • 28
    • 0029130042 scopus 로고
    • Altered Th1/Th2 cytokine profiles in the intestinal mucosa of patients with inflammatory bowel disease as assessed by quantitative reversed transcribed polymerase chain reaction (RT-PCR)
    • Niesser M, Vol BA. Altered Th1/Th2 cytokine profiles in the intestinal mucosa of patients with inflammatory bowel disease as assessed by quantitative reversed transcribed polymerase chain reaction (RT-PCR). Clin Exp Immunol 1995;101:428.
    • (1995) Clin. Exp. Immunol. , vol.101 , pp. 428
    • Niesser, M.1    Vol, B.A.2
  • 29
    • 33746176176 scopus 로고    scopus 로고
    • Fontolizumab, a humanized anti-interferon gamma antibody, demonstrates safety and clinical activity in patients with moderate to severe Crohn's disease
    • Hommes DW, Mikhajlova TL, Stoinov S, et al. Fontolizumab, a humanized anti-interferon gamma antibody, demonstrates safety and clinical activity in patients with moderate to severe Crohn's disease. Gut 2006;29:1131.
    • (2006) Gut , vol.29 , pp. 1131
    • Hommes, D.W.1    Mikhajlova, T.L.2    Stoinov, S.3
  • 30
    • 0345447585 scopus 로고    scopus 로고
    • Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms
    • Bruewer M, Luegering A, Kucharzik T, et al. Proinflammatory cytokines disrupt epithelial barrier function by apoptosis-independent mechanisms. J Immunol 2003;171:6164.
    • (2003) J. Immunol. , vol.171 , pp. 6164
    • Bruewer, M.1    Luegering, A.2    Kucharzik, T.3
  • 31
    • 34247598857 scopus 로고    scopus 로고
    • Loss of the tight junction protein in dextran sulfate sodium induced colitis
    • Poritz LS, Garver K, Green C, et al. Loss of the tight junction protein in dextran sulfate sodium induced colitis. J Surg Res 2007;140:12.
    • (2007) J. Surg. Res. , vol.140 , pp. 12
    • Poritz, L.S.1    Garver, K.2    Green, C.3
  • 33
    • 85030591196 scopus 로고    scopus 로고
    • Dextran sodium sulfate (DSS) induced colitis in the Th2 deficient Stat6 Knockout (Stat6-). Mouse
    • Poritz LS, Garver K, Zhang W, et al. Dextran Sodium Sulfate (DSS) Induced Colitis in the Th2 Deficient Stat6 Knockout (Stat6-). Mouse. Dis Col Rectum 2004;46: A2.
    • (2004) Dis. Col Rectum. , vol.46
    • Poritz, L.S.1    Garver, K.2    Zhang, W.3
  • 34
    • 26444484949 scopus 로고    scopus 로고
    • DSS-induced colitis is exacerbated in STAT-6 knockout mice
    • Elrod JW, Laroux FS, Houghton J, et al. DSS-induced colitis is exacerbated in STAT-6 knockout mice. Inflamm Bowel Dis 2005;11:883.
    • (2005) Inflamm. Bowel Dis. , vol.11 , pp. 883
    • Elrod, J.W.1    Laroux, F.S.2    Houghton, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.