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Volumn 11, Issue 10, 2005, Pages 883-889

DSS-induced colitis is exacerbated in STAT-6 knockout mice

Author keywords

Inducible NO synthase; Inflammatory bowel disease; Interferon

Indexed keywords

DEXTRAN SULFATE; GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRATE; NITRITE; STAT6 PROTEIN;

EID: 26444484949     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1097/01.MIB.0000182871.76434.57     Document Type: Article
Times cited : (19)

References (33)
  • 1
    • 0027074753 scopus 로고
    • Neutrophils, nitrogen oxides, and inflammatory, bowel disease
    • Grisham MB, Yamada T. Neutrophils, nitrogen oxides, and inflammatory, bowel disease. Ann N Y Acad Sci. 1992;664:103-115.
    • (1992) Ann N Y Acad Sci , vol.664 , pp. 103-115
    • Grisham, M.B.1    Yamada, T.2
  • 2
    • 0242416575 scopus 로고    scopus 로고
    • Cytokines and transcription factors that regulate T helper cell differentiation: New players and new insights
    • Agnello D, Lankford CS, Bream J, et al. Cytokines and transcription factors that regulate T helper cell differentiation: new players and new insights. J Clin Immunol. 2003;23:147-161.
    • (2003) J Clin Immunol , vol.23 , pp. 147-161
    • Agnello, D.1    Lankford, C.S.2    Bream, J.3
  • 3
    • 0037338992 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 6 gene G2964A polymorphism and inflammatory bowel disease
    • Xia B, Crusius JB, Wu J, et al. Signal transducer and activator of transcription 6 gene G2964A polymorphism and inflammatory bowel disease. Clin Exp Immunol. 2003;131:446-450.
    • (2003) Clin Exp Immunol , vol.131 , pp. 446-450
    • Xia, B.1    Crusius, J.B.2    Wu, J.3
  • 4
    • 0032996486 scopus 로고    scopus 로고
    • The Jak-STAT pathway: Cytokine signaling from the receptor to the nucleus
    • Heim MH. The Jak-STAT pathway: cytokine signaling from the receptor to the nucleus. J Recept Signal Transduct Res. 1999;19:75-120.
    • (1999) J Recept Signal Transduct Res , vol.19 , pp. 75-120
    • Heim, M.H.1
  • 5
    • 0030587813 scopus 로고    scopus 로고
    • Impaired IL-13-mediated functions of macrophages in STAT-6-deficient mice
    • Takeda K, Kamanaka M, Tanaka T, et al. Impaired IL-13-mediated functions of macrophages in STAT-6-deficient mice. J Immunol. 1996;157:3220-3222.
    • (1996) J Immunol , vol.157 , pp. 3220-3222
    • Takeda, K.1    Kamanaka, M.2    Tanaka, T.3
  • 6
    • 0242441469 scopus 로고    scopus 로고
    • No evidence for involvement of IL-4R and CD11B from the IBD1 region and STAT-6 in the IBD2 region in Crohn's disease
    • de Jong DJ, Franke B, Naber AH, et al. No evidence for involvement of IL-4R and CD11B from the IBD1 region and STAT-6 in the IBD2 region in Crohn's disease. Eur J Hum Genet. 2003;11:884-887.
    • (2003) Eur J Hum Genet , vol.11 , pp. 884-887
    • De Jong, D.J.1    Franke, B.2    Naber, A.H.3
  • 7
    • 18044403415 scopus 로고    scopus 로고
    • Interleukin-4 and interleukin-4 receptor gene polymorphisms in inflammatory bowel diseases
    • Klein W, Tromm A, Griga T, et al. Interleukin-4 and interleukin-4 receptor gene polymorphisms in inflammatory bowel diseases. Genes Immun. 2001;2:287-289.
    • (2001) Genes Immun , vol.2 , pp. 287-289
    • Klein, W.1    Tromm, A.2    Griga, T.3
  • 8
    • 0037108525 scopus 로고    scopus 로고
    • Role of STAT-6 and mast cells in IL-4- And IL-13-induced alterations in murine intestinal epithelial cell function
    • Madden KB, Whitman L, Sullivan C, et al. Role of STAT-6 and mast cells in IL-4- and IL-13-induced alterations in murine intestinal epithelial cell function. J Immunol. 2002;169:4417-4422.
    • (2002) J Immunol , vol.169 , pp. 4417-4422
    • Madden, K.B.1    Whitman, L.2    Sullivan, C.3
  • 9
    • 0037222318 scopus 로고    scopus 로고
    • Development of colitis in signal transducers and activators of transcription 6-deficient T-cell receptor alpha-deficient mice: A potential role of signal transducers and activators of transcription 6-independent interleukin-4 signaling for the generation of Th2-biased pathological CD4+ betabeta T cells
    • Okuda Y, Takahashi I, Kim JK, et al. Development of colitis in signal transducers and activators of transcription 6-deficient T-cell receptor alpha-deficient mice: a potential role of signal transducers and activators of transcription 6-independent interleukin-4 signaling for the generation of Th2-biased pathological CD4+ betabeta T cells. Am J Pathol. 2003;162:263-271.
    • (2003) Am J Pathol , vol.162 , pp. 263-271
    • Okuda, Y.1    Takahashi, I.2    Kim, J.K.3
  • 10
    • 0035158627 scopus 로고    scopus 로고
    • Regulation of murine intestinal inflammation by reactive metabolites of oxygen and nitrogen: Divergent roles of superoxide and nitric oxide
    • Krieglstein CF, Cerwinka WH, Laroux FS, et al. Regulation of murine intestinal inflammation by reactive metabolites of oxygen and nitrogen: divergent roles of superoxide and nitric oxide. J Exp Med. 2001;194:1207-1218.
    • (2001) J Exp Med , vol.194 , pp. 1207-1218
    • Krieglstein, C.F.1    Cerwinka, W.H.2    Laroux, F.S.3
  • 11
    • 0034333259 scopus 로고    scopus 로고
    • Deficient iNOS in inflammatory bowel disease intestinal microvascular endothelial cells results in increased leukocyte adhesion
    • Binion DG, Rafiee P, Ramanujam KS, et al. Deficient iNOS in inflammatory bowel disease intestinal microvascular endothelial cells results in increased leukocyte adhesion. Free Radic Biol Med. 2000;29:881-888.
    • (2000) Free Radic Biol Med , vol.29 , pp. 881-888
    • Binion, D.G.1    Rafiee, P.2    Ramanujam, K.S.3
  • 12
    • 0035057241 scopus 로고    scopus 로고
    • Inhibition of nitric oxide synthesis by aminoguanidine increases intestinal damage in the acute phase of rat TNB-colitis
    • Dikopoulos N, Nussler AK, Liptay S, et al. Inhibition of nitric oxide synthesis by aminoguanidine increases intestinal damage in the acute phase of rat TNB-colitis. Eur J Clin Invest. 2001;31:234-239.
    • (2001) Eur J Clin Invest , vol.31 , pp. 234-239
    • Dikopoulos, N.1    Nussler, A.K.2    Liptay, S.3
  • 13
    • 0034127618 scopus 로고    scopus 로고
    • Role of inducible nitric oxide synthase in dextran sulphate sodium-induced colitis
    • Yoshida Y, Iwai A, Itoh K, et al. Role of inducible nitric oxide synthase in dextran sulphate sodium-induced colitis. Aliment Pharmacol Ther. 2000;14(Suppl 1):26-32.
    • (2000) Aliment Pharmacol Ther , vol.14 , Issue.SUPPL. 1 , pp. 26-32
    • Yoshida, Y.1    Iwai, A.2    Itoh, K.3
  • 14
    • 0346996626 scopus 로고    scopus 로고
    • Increased disease activity in eNOS-deficient mice in experimental colitis
    • Sasaki M, Bharwani S, Jordan P, et al. Increased disease activity in eNOS-deficient mice in experimental colitis. Free Radic Biol Med. 2003;35:1679-1687.
    • (2003) Free Radic Biol Med , vol.35 , pp. 1679-1687
    • Sasaki, M.1    Bharwani, S.2    Jordan, P.3
  • 15
    • 0034967004 scopus 로고    scopus 로고
    • iNOS upregulation mediates oxidant-induced disruption of F-actin and barrier of intestinal monolayers
    • Banan A, Fields JZ, Zhang Y, et al. iNOS upregulation mediates oxidant-induced disruption of F-actin and barrier of intestinal monolayers. Am J Physiol Gastrointest Liver Physiol. 2001;280:G1234-G1246.
    • (2001) Am J Physiol Gastrointest Liver Physiol , vol.280
    • Banan, A.1    Fields, J.Z.2    Zhang, Y.3
  • 16
    • 0037405112 scopus 로고    scopus 로고
    • The delta-isoform of protein kinase C causes inducible nitric-oxide synthase and nitric oxide upregulation: Key mechanism for oxidant-induced carbonylation, nitration, and disassembly of the microtubule cytoskeleton and hyperpermeability of barrier of intestinal epithelia
    • Banan A, Farhadi A, Fields JZ, et al. The delta-isoform of protein kinase C causes inducible nitric-oxide synthase and nitric oxide upregulation: key mechanism for oxidant-induced carbonylation, nitration, and disassembly of the microtubule cytoskeleton and hyperpermeability of barrier of intestinal epithelia. J Pharmacol Exp Ther. 2003;305:482-494.
    • (2003) J Pharmacol Exp Ther , vol.305 , pp. 482-494
    • Banan, A.1    Farhadi, A.2    Fields, J.Z.3
  • 17
    • 0141679474 scopus 로고    scopus 로고
    • Key role of PLC-gamma in EGF protection of epithelial barrier against iNOS upregulation and F-actin nitration and disassembly
    • Banan A, Zhang LJ, Shaikh M, et al. Key role of PLC-gamma in EGF protection of epithelial barrier against iNOS upregulation and F-actin nitration and disassembly. Am J Physiol Cell Physiol. 2003;285:C977-C993.
    • (2003) Am J Physiol Cell Physiol , vol.285
    • Banan, A.1    Zhang, L.J.2    Shaikh, M.3
  • 18
    • 0032828405 scopus 로고    scopus 로고
    • Expression of NOS II and its role in experimental small bowel ulceration in rats
    • Chen K, Hirota S, Wasa M, et al. Expression of NOS II and its role in experimental small bowel ulceration in rats. Surgery. 1999;126:553-561.
    • (1999) Surgery , vol.126 , pp. 553-561
    • Chen, K.1    Hirota, S.2    Wasa, M.3
  • 19
    • 0033891418 scopus 로고    scopus 로고
    • IFN-gamma and IL-4 differently regulate inducible NO synthase gene expression through IRF-1 modulation
    • Coccia EM, Stellacci E, Marziali G, et al. IFN-gamma and IL-4 differently regulate inducible NO synthase gene expression through IRF-1 modulation. Int Immunol. 2000;12:977-985.
    • (2000) Int Immunol , vol.12 , pp. 977-985
    • Coccia, E.M.1    Stellacci, E.2    Marziali, G.3
  • 20
    • 0033865650 scopus 로고    scopus 로고
    • IL-4 and IL-13 upregulate arginase 1 expression by cAMP and JAK/STAT-6 pathways in vascular smooth muscle cells
    • Wei LH, Jacobs AT, Morris SM Jr, et al. IL-4 and IL-13 upregulate arginase 1 expression by cAMP and JAK/STAT-6 pathways in vascular smooth muscle cells. Am J Physiol Cell Physiol. 2000;279:C248-C256.
    • (2000) Am J Physiol Cell Physiol , vol.279
    • Wei, L.H.1    Jacobs, A.T.2    Morris Jr., S.M.3
  • 21
    • 0035865047 scopus 로고    scopus 로고
    • Cutting edge: STAT-6-dependent substrate depletion regulates nitric oxide production
    • Rutschman R, Lang R, Hesse M, et al. Cutting edge: STAT-6-dependent substrate depletion regulates nitric oxide production. J Immunol. 2001;166:2173-2177.
    • (2001) J Immunol , vol.166 , pp. 2173-2177
    • Rutschman, R.1    Lang, R.2    Hesse, M.3
  • 22
    • 0031467628 scopus 로고    scopus 로고
    • Therapeutic effects of interleukin-4 gene transfer in experimental inflammatory bowel disease
    • Hogaboam CM, Vallance BA, Kumar A, et al. Therapeutic effects of interleukin-4 gene transfer in experimental inflammatory bowel disease. J Clin Invest. 1997;100:2766-2776.
    • (1997) J Clin Invest , vol.100 , pp. 2766-2776
    • Hogaboam, C.M.1    Vallance, B.A.2    Kumar, A.3
  • 23
    • 0026631007 scopus 로고
    • Experimental colitis in animal models
    • Kim HS, Berstad A. Experimental colitis in animal models. Scand J Gastroenterol. 1992;27:529-537.
    • (1992) Scand J Gastroenterol , vol.27 , pp. 529-537
    • Kim, H.S.1    Berstad, A.2
  • 24
    • 0027527363 scopus 로고
    • A fluorometric assay for the measurement of nitrite in biological samples
    • Misko TP, Schilling RJ, Salvemini D, et al. A fluorometric assay for the measurement of nitrite in biological samples. Anal Biochem. 1993;214:11-16.
    • (1993) Anal Biochem , vol.214 , pp. 11-16
    • Misko, T.P.1    Schilling, R.J.2    Salvemini, D.3
  • 25
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C[T]) Method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C[T]) Method. Methods. 2001;25:402-408.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 26
    • 0030624779 scopus 로고    scopus 로고
    • Role of animal models for the pathogenesis and treatment of inflammatory bowel disease
    • Dieleman LA, Pena AS, Meuwissen SG, et al. Role of animal models for the pathogenesis and treatment of inflammatory bowel disease. Scand J Gastroenterol Suppl. 1997;223:99-104.
    • (1997) Scand J Gastroenterol Suppl , vol.223 , pp. 99-104
    • Dieleman, L.A.1    Pena, A.S.2    Meuwissen, S.G.3
  • 27
    • 0034893711 scopus 로고    scopus 로고
    • Suppression of acute experimental colitis by a highly selective inducible nitric-oxide synthase inhibitor, N-(3-[aminomethyl]benzyl)acetamidine
    • Kankuri E, Vaali K, Knowles RG, et al. Suppression of acute experimental colitis by a highly selective inducible nitric-oxide synthase inhibitor, N-(3-[aminomethyl]benzyl)acetamidine. J Pharmacol Exp Ther. 2001;298:1128-1132.
    • (2001) J Pharmacol Exp Ther , vol.298 , pp. 1128-1132
    • Kankuri, E.1    Vaali, K.2    Knowles, R.G.3
  • 28
    • 0036402375 scopus 로고    scopus 로고
    • Onchocerca volvulus keratitis (river blindness) is exacerbated in BALB/c IL-4 gene knockout mice
    • Hall LR, Berger RB, Diaconu E, et al. Onchocerca volvulus keratitis (river blindness) is exacerbated in BALB/c IL-4 gene knockout mice. Cell Immunol. 2002;216:1-5.
    • (2002) Cell Immunol , vol.216 , pp. 1-5
    • Hall, L.R.1    Berger, R.B.2    Diaconu, E.3
  • 29
    • 0344736701 scopus 로고    scopus 로고
    • Myeloperoxidase upregulates the catalytic activity of inducible nitric oxide synthase by preventing nitric oxide feedback inhibition
    • Galijasevic S, Saed GM, Diamond MP, et al. Myeloperoxidase upregulates the catalytic activity of inducible nitric oxide synthase by preventing nitric oxide feedback inhibition. Proc Natl Acad Sci USA. 2003;100:14766-14771.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 14766-14771
    • Galijasevic, S.1    Saed, G.M.2    Diamond, M.P.3
  • 30
    • 0242406890 scopus 로고    scopus 로고
    • Intratracheal IL-13 induces eosinophilic esophagitis by an IL-5, eotaxin-1, and STAT-6-dependent mechanism
    • Mishra A, Rothenberg ME. Intratracheal IL-13 induces eosinophilic esophagitis by an IL-5, eotaxin-1, and STAT-6-dependent mechanism. Gastroenterology. 2003;125:1419-1427.
    • (2003) Gastroenterology , vol.125 , pp. 1419-1427
    • Mishra, A.1    Rothenberg, M.E.2
  • 31
    • 0032482159 scopus 로고    scopus 로고
    • Abrogation of bronchial eosinophilic inflammation and airway hyperreactivity in signal transducers and activators of transcription (STAT)6-deficient mice
    • Akimoto T, Numata F, Tamura M, et al. Abrogation of bronchial eosinophilic inflammation and airway hyperreactivity in signal transducers and activators of transcription (STAT)6-deficient mice. J Exp Med. 1998;187:1537-1542.
    • (1998) J Exp Med , vol.187 , pp. 1537-1542
    • Akimoto, T.1    Numata, F.2    Tamura, M.3
  • 32
    • 0035821221 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 6 controls chemokine production and T helper cell type 2 cell trafficking in allergic pulmonary inflammation
    • Mathew A, MacLean JA, DeHaan E, et al. Signal transducer and activator of transcription 6 controls chemokine production and T helper cell type 2 cell trafficking in allergic pulmonary inflammation. J Exp Med. 2001;193:1087-1096.
    • (2001) J Exp Med , vol.193 , pp. 1087-1096
    • Mathew, A.1    MacLean, J.A.2    Dehaan, E.3
  • 33
    • 0034757324 scopus 로고    scopus 로고
    • Interferongamma and interleukin-10 reciprocally regulate endothelial junction integrity and barrier function
    • Oshima T, Laroux FS, Coe LL, et al. Interferongamma and interleukin-10 reciprocally regulate endothelial junction integrity and barrier function. Microvasc Res. 2001;61:130-143.
    • (2001) Microvasc Res , vol.61 , pp. 130-143
    • Oshima, T.1    Laroux, F.S.2    Coe, L.L.3


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