메뉴 건너뛰기




Volumn 74, Issue 4, 2008, Pages 187-200

Computational approaches and modelling of signaling processes immune system

Author keywords

[No Author keywords available]

Indexed keywords

CELL SIGNALING; COMPUTATIONAL APPROACH; DRUG TARGETS; EFFECTIVE TOOL; EXPERIMENTAL ANALYSIS; EXPERIMENTAL METHODS; IMMUNE CELLS; IMMUNE MECHANISM; IMMUNE SYSTEMS; MODELLING APPROACHES; NEW DIRECTIONS; RISK FREE; SIGNALING NETWORKS; SIGNALING PROCESS; SYSTEMS BIOLOGY; T CELLS; THEORETICAL APPROACH; THERAPEUTIC STRATEGY;

EID: 77955948563     PISSN: 03700046     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (4)

References (68)
  • 2
    • 0034641898 scopus 로고    scopus 로고
    • Cd95's deadly mission in the immune system
    • Krammer PH, CD95's deadly mission in the immune system Nature 407 (2000) 789
    • (2000) Nature , vol.407 , pp. 789
    • Krammer, P.H.1
  • 3
    • 2942588906 scopus 로고    scopus 로고
    • Mathematical and computational models of immune-receptor signalling
    • Goldstein B, JR Faeder and WS Hlavacek, Mathematical and computational models of immune-receptor signalling Nat Rev Immunol 4 (2004) 445
    • (2004) Nat Rev Immunol , vol.4 , pp. 445
    • Goldstein, B.1    Faeder, J.R.2    Hlavacek, W.S.3
  • 5
    • 0015609281 scopus 로고
    • The logical analysis of continuous, non-linear biochemical control networks
    • Glass L and SA Kauffman, The logical analysis of continuous, non-linear biochemical control networks J Theor Biol 39 (1973) 103
    • (1973) J Theor Biol , vol.39 , pp. 103
    • Glass, L.1    Kauffman, S.A.2
  • 6
    • 0345983657 scopus 로고    scopus 로고
    • From boolean to probabilistic boolean networks as models of genetic regulator networks
    • Shmulevich I, E Dougherty and W Zhang, From Boolean to Probabilistic Boolean Networks as Models of Genetic Regulator Networks, IEEE (2002) 1778
    • (2002) IEEE , pp. 1778
    • Shmulevich, I.1    Dougherty, E.2    Zhang, W.3
  • 7
    • 0842326617 scopus 로고    scopus 로고
    • A logical analysis of the process of t cell activation: Different consequences depending on the state of cd28 engagement
    • Sarkar A and BR Franza, A logical analysis of the process of T cell activation: different consequences depending on the state of CD28 engagement J Theor Biol 226 (2004) 455
    • (2004) J Theor Biol , vol.226 , pp. 455
    • Sarkar, A.1    Franza, B.R.2
  • 11
    • 34447551397 scopus 로고    scopus 로고
    • Structural and functional analysis of cellular networks with cell net analyzer
    • S Klamt, J Saez-Rodriguez and ED Gilles. Structural and functional analysis of cellular networks with Cell Net Analyzer BMC Syst Biol 1 (2007) 2
    • (2007) BMC Syst Biol , vol.1 , pp. 2
    • Klamt, S.1    Saez-Rodriguez, J.2    Gilles, E.D.3
  • 15
    • 3042699469 scopus 로고    scopus 로고
    • Model validation of biological pathways using petri nets-demonstrated for apoptosis
    • M Heiner, I Koch and J Will, Model validation of biological pathways using Petri nets-demonstrated for apoptosis Biosystems 75 (2004) 15
    • (2004) Biosystems , vol.75 , pp. 15
    • Heiner, M.1    Koch, I.2    Will, J.3
  • 16
    • 33845417184 scopus 로고    scopus 로고
    • Application of petri net based analysis techniques to signal transduction pathways
    • A Sackmann, M Heiner and I Koch, Application of Petri net based analysis techniques to signal transduction pathways BMC 'Bioinformatics 7 (2006) 482
    • (2006) BMC 'Bioinformatics , vol.7 , pp. 482
    • Sackmann, A.1    Heiner, M.2    Koch, I.3
  • 17
    • 13244260797 scopus 로고    scopus 로고
    • Modeling of cell signaling pathways in macrophages by- semantic networks
    • M Hsing, JL Bellenson, C Shankey and A Cherkasov, Modeling of cell signaling pathways in macrophages by- semantic networks BMC Bioinformatics 5 (2004) 156
    • (2004) BMC Bioinformatics , vol.5 , pp. 156
    • Hsing, M.1    Bellenson, J.L.2    Shankey, C.3    Cherkasov, A.4
  • 18
    • 0029063148 scopus 로고
    • Kinetic proofreading in t-cell receptor signal transduction
    • TW McKeithan, Kinetic proofreading in T-cell receptor signal transduction Proc Natl Acad Sci U S A 92 (1995) 5042
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 5042
    • McKeithan, T.W.1
  • 19
    • 0032563231 scopus 로고    scopus 로고
    • Fidelity of t cell activation through multistep t cell receptor zeta phosphorylation
    • EN Kersh, AS Shaw and PM Allen Fidelity of T cell activation through multistep T cell receptor zeta phosphorylation Science 281 (1998) 572
    • (1998) Science , vol.281 , pp. 572
    • Kersh, E.N.1    Shaw, A.S.2    Allen, P.M.3
  • 21
    • 0032977676 scopus 로고    scopus 로고
    • A kinetic differentiation model for the action of altered tcr ligands
    • GM Lord, RI Lechler and AJ George, A kinetic differentiation model for the action of altered TCR ligands Immunol Today 20 (1999) 33
    • (1999) Immunol Today , vol.20 , pp. 33
    • Lord, G.M.1    Lechler, R.I.2    George, A.J.3
  • 22
    • 0032562995 scopus 로고    scopus 로고
    • An unusual mechanism for ligand antagonism
    • C Torigoe, JK Inman and H Metzger, An unusual mechanism for ligand antagonism Science 281 (1998) 568
    • (1998) Science , vol.281 , pp. 568
    • Torigoe, C.1    Inman, J.K.2    Metzger, H.3
  • 23
    • 0035912821 scopus 로고    scopus 로고
    • Kinetic proofreading models for cell signaling predict ways to escape kinetic proofreading
    • WS Hlavacek, A Redondo, H Metzger, C Wofsy and B Goldstein, Kinetic proofreading models for cell signaling predict ways to escape kinetic proofreading Proc Natl Acad Sci USA 98 (2001) 7295
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 7295
    • Hlavacek, W.S.1    Redondo, A.2    Metzger, H.3    Wofsy, C.4    Goldstein, B.5
  • 24
    • 0036739732 scopus 로고    scopus 로고
    • Kinetic proofreading in receptor-mediated transduction of cellular signals: Receptor aggregation, partially activated receptors, and cytosolic messengers
    • WS Hlavacek, A Redondo, C Wofsy and B Goldstein, Kinetic proofreading in receptor-mediated transduction of cellular signals: receptor aggregation, partially activated receptors, and cytosolic messengers Bull Math Biol 64 (2002) 887
    • (2002) Bull Math Biol , vol.64 , pp. 887
    • Hlavacek, W.S.1    Redondo, A.2    Wofsy, C.3    Goldstein, B.4
  • 25
    • 0036898764 scopus 로고    scopus 로고
    • A temporal and spatial summation model for t-cell activation: Signal integration and antigen decoding
    • J Rachmilewitz and A Lanzavecchia, A temporal and spatial summation model for T-cell activation: signal integration and antigen decoding Trends Immunol 23 (2002) 592
    • (2002) Trends Immunol , vol.23 , pp. 592
    • Rachmilewitz, J.1    Lanzavecchia, A.2
  • 27
    • 0037047611 scopus 로고    scopus 로고
    • Map kinase phosphatase as a locus of flexibility in a mitogen-acti vated protein kinase signaling network
    • US Bhalla, PT Ram and R Iyengar, MAP kinase phosphatase as a locus of flexibility in a mitogen-acti vated protein kinase signaling network Science 297 (2002) 1018
    • (2002) Science , vol.297 , pp. 1018
    • Bhalla, U.S.1    Ram, P.T.2    Iyengar, R.3
  • 28
    • 33749370872 scopus 로고    scopus 로고
    • Molecular switches at the synapse emerge from receptor and kinase traffic
    • A Hayer and US Bhalla, Molecular switches at the synapse emerge from receptor and kinase traffic PLoS Comput Biol 1 (2005) 137
    • (2005) PLoS Comput Biol , vol.1 , pp. 137
    • Hayer, A.1    Bhalla, U.S.2
  • 29
    • 10244252785 scopus 로고    scopus 로고
    • A model-based optimization framework for the inference on gene regulatory networks from dna array data
    • R Thomas, S Mehrotra, ET Papoutsakis and V Hatzimanikatis, A model-based optimization framework for the inference on gene regulatory networks from DNA array data Bioinformatics 20 (2004) 3221
    • (2004) Bioinformatics , vol.20 , pp. 3221
    • Thomas, R.1    Mehrotra, S.2    Papoutsakis, E.T.3    Hatzimanikatis, V.4
  • 30
  • 31
    • 33644963955 scopus 로고    scopus 로고
    • A medical bioinformatics approach for metabolic disorders: Biomedical data prediction, modeling, and systematic analysis
    • M Chen and R Hofestadt, A medical bioinformatics approach for metabolic disorders: biomedical data prediction, modeling, and systematic analysis J Biomed Inform 39 (2006) 147
    • (2006) J Biomed Inform , vol.39 , pp. 147
    • Chen, M.1    Hofestadt, R.2
  • 32
    • 2342469914 scopus 로고    scopus 로고
    • Stochastic model of protein-protein interaction: Why signaling proteins need to be colocalized
    • NN Batada, LA Shepp and DO Siegmund, Stochastic model of protein-protein interaction: why signaling proteins need to be colocalized Proc Natl Acad Sci USA 101 (2004) 6445
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 6445
    • Batada, N.N.1    Shepp, L.A.2    Siegmund, D.O.3
  • 33
    • 33748452685 scopus 로고    scopus 로고
    • T-cell activation: A queuing theory analysis at low agonist density
    • JR Wedagedera and NJ Burroughs, T-cell activation: A queuing theory analysis at low agonist density Biophys J 91 (2006) 1604
    • (2006) Biophys J , vol.91 , pp. 1604
    • Wedagedera, J.R.1    Burroughs, N.J.2
  • 36
    • 0035997009 scopus 로고    scopus 로고
    • Extreme pathway analysis of human red blood cell metabolism
    • SJ Wiback and BO Palsson, Extreme pathway analysis of human red blood cell metabolism Biophys .J 83 (2002) 808
    • (2002) Biophys .J , vol.83 , pp. 808
    • Wiback, S.J.1    Palsson, B.O.2
  • 38
    • 33845226621 scopus 로고    scopus 로고
    • Analysis of signalling pathways using the prism model checker
    • M Calder, V Vyshemirsky, D Gilbert and R Orton, Analysis of signalling pathways using the PRISM model checker, CMSB 05 (2005)
    • (2005) CMSB 05
    • Calder, M.1    Vyshemirsky, V.2    Gilbert, D.3    Orton, R.4
  • 40
    • 33846542982 scopus 로고    scopus 로고
    • Emergent dynamics of thymocyte development and lineage determination
    • S Efroni, D Harel and IR Cohen, Emergent dynamics of thymocyte development and lineage determination PLoS Comput Biol 3 (2007) el3
    • (2007) PLoS Comput Biol , vol.3
    • Efroni, S.1    Harel, D.2    Cohen, I.R.3
  • 41
    • 0032492078 scopus 로고    scopus 로고
    • Dynamics of cytotoxic t-lymphocyte exhaustion
    • D Wodarz. P Klenerman and MA Nowak Dynamics of cytotoxic T-lymphocyte exhaustion Proc Biol Sci 265 (1998) 191
    • (1998) Proc Biol Sci , vol.265 , pp. 191
    • Wodarz, D.1    Klenerman, P.2    Nowak, M.A.3
  • 43
    • 0023021340 scopus 로고
    • Interactions between macrophages and t-lymphocytes: Tumor sneaking through intrinsic to helper t cell dynamics
    • De Boer RJ and P Hogeweg, Interactions between macrophages and T-lymphocytes: tumor sneaking through intrinsic to helper T cell dynamics J Theor Biol 120 (1986) 331
    • (1986) J Theor Biol , vol.120 , pp. 331
    • De Boer, R.J.1    Hogeweg, P.2
  • 44
    • 0021894588 scopus 로고
    • Macrophage i lymphocyte interactions in the antitumor immune response: A mathematical model
    • De Boer RJ, Hogeweg P, Dullens HF. RA De Weger and W Den Otter Macrophage I lymphocyte interactions in the antitumor immune response: a mathematical model J Immunol 134 (1985) 2748
    • (1985) J Immunol , vol.134 , pp. 2748
    • De Boer, R.J.1    Hogeweg, P.2    Dullens, H.F.3    De Weger, R.A.4    Den Otter, W.5
  • 46
    • 0028388757 scopus 로고
    • Nonlinear dynamics of immunogenic tumors: Parameter estimation and global bifurcation analysis
    • Kuznetsov VA, IA Makalkin, MA Taylor and AS Perelson. Nonlinear dynamics of immunogenic tumors: parameter estimation and global bifurcation analysis Bull Math Biol 56 (1994) 295
    • (1994) Bull Math Biol , vol.56 , pp. 295
    • Kuznetsov, V.A.1    Makalkin, I.A.2    Taylor, M.A.3    Perelson, A.S.4
  • 47
    • 0032160863 scopus 로고    scopus 로고
    • Modeling immunotherapy of the tumor-immune interaction
    • Kirschner D and JC Panetta Modeling immunotherapy of the tumor-immune interaction J Math Biol 37 (1998) 235
    • (1998) J Math Biol , vol.37 , pp. 235
    • Kirschner, D.1    Panetta, J.C.2
  • 48
    • 0038575165 scopus 로고    scopus 로고
    • Mathematical modelling of the competition between tumors and immune system considering the role of the antibodies
    • Kolev M, Mathematical modelling of the competition between tumors and immune system considering the role of the antibodies. Math Comput Model 37 (2003) 1143
    • (2003) Math Comput Model , vol.37 , pp. 1143
    • Kolev, M.1
  • 49
    • 35248819749 scopus 로고    scopus 로고
    • Optimal control of treatment in a mathematical model of chronic myelogenous leukemia
    • Nanda S, H Moore and S Lenhart, Optimal control of treatment in a mathematical model of chronic myelogenous leukemia Math Biosci 210 (2007) 143
    • (2007) Math Biosci , vol.210 , pp. 143
    • Nanda, S.1    Moore, H.2    Lenhart, S.3
  • 50
    • 34547702210 scopus 로고    scopus 로고
    • An optimal dynamic inversion-based neuro-adaptive approach for treatment of chronic myelogenous leukemia
    • Padhi R and M Kothari, An optimal dynamic inversion-based neuro-adaptive approach for treatment of chronic myelogenous leukemia Comput Methods Programs Biomed 87 (2007) 208
    • (2007) Comput Methods Programs Biomed , vol.87 , pp. 208
    • Padhi, R.1    Kothari, M.2
  • 52
    • 33749524667 scopus 로고    scopus 로고
    • Dynamic modeling of imatinib-treated chronic myeloid leukemia: Functional insights and clinical implications
    • I Roeder, M Horn, Glauche, A Hochhaus, MC Mueller and M Loeffler, Dynamic modeling of imatinib-treated chronic myeloid leukemia: functional insights and clinical implications Nat Med 12 (2006) 1181
    • (2006) Nat Med , vol.12 , pp. 1181
    • Roeder, I.1    Glauche, H.M.2    Hochhaus, A.3    Mueller, M.C.4    Loeffler, M.5
  • 53
    • 46249101269 scopus 로고    scopus 로고
    • Dynamics and potential impact of the immune response to chronic myelogenous leukemia
    • PS Kim, PP Lee and D Levy, Dynamics and potential impact of the immune response to chronic myelogenous leukemia PLoS Comput Biol 4 (2008) el000095
    • (2008) PLoS Comput Biol , vol.4
    • Kim, P.S.1    Lee, P.P.2    Levy, D.3
  • 54
    • 33749440614 scopus 로고    scopus 로고
    • Hopf bifurcation in a delayed model for tumor- immune system competition with negative immune response
    • Yafia R, Hopf bifurcation in a delayed model for tumor- immune system competition with negative immune response Discrete Dyn Nat Soc 2006 (2006) 1
    • (2006) Discrete Dyn Nat Soc , vol.2006 , pp. 1
    • Yafia, R.1
  • 55
    • 33749437893 scopus 로고    scopus 로고
    • Stability of limit cycle in a delayed model for tumor- immune system competition with negative immune response
    • Yafia R, Stability of limit cycle in a delayed model for tumor- immune system competition with negative immune response. Discrete Dyn Nat Soc 2006 (2006) 1
    • (2006) Discrete Dyn Nat Soc , vol.2006 , pp. 1
    • Yafia, R.1
  • 56
    • 22144467632 scopus 로고    scopus 로고
    • Cancer self remission and tumor stability-a stochastic approach
    • Sarkar RR and S Banerjee, Cancer self remission and tumor stability-a stochastic approach Math Biosci 196 (2005) 65
    • (2005) Math Biosci , vol.196 , pp. 65
    • Sarkar, R.R.1    Banerjee, S.2
  • 57
    • 37549035821 scopus 로고    scopus 로고
    • Delay-induced model for tumor-immune interaction and control of malignant tumor growth
    • Banerjee S and RR Sarkar, Delay-induced model for tumor-immune interaction and control of malignant tumor growth Biosystems 91 (2008) 268
    • (2008) Biosystems , vol.91 , pp. 268
    • Banerjee, S.1    Sarkar, R.R.2
  • 58
    • 0034376646 scopus 로고    scopus 로고
    • Cancer self remission and tumor instability-a cybernetic analysis: Towards a fresh paradigm for cancer treatment
    • Majumder DD and P Roy; Cancer self remission and tumor instability-a cybernetic analysis: towards a fresh paradigm for cancer treatment Cybernetics 29 (2000) 896
    • (2000) Cybernetics , vol.29 , pp. 896
    • Majumder, D.D.1    Roy, P.2
  • 61
    • 84965808621 scopus 로고
    • Fluctuations in malignant tumors with spontaneous recession
    • Rohdenburg G, Fluctuations in malignant tumors with spontaneous recession J Cancer Res 3 (1918) 193
    • (1918) J Cancer Res , vol.3 , pp. 193
    • Rohdenburg, G.1
  • 62
  • 63
    • 0009899087 scopus 로고    scopus 로고
    • A dynamical analysis of spontaneous cancer regression
    • Roy P and PK Sen, A dynamical analysis of spontaneous cancer regression J. Investigat. Med. 44 (1996) 333
    • (1996) J. Investigat. Med. , vol.44 , pp. 333
    • Roy, P.1    Sen, P.K.2
  • 64
    • 0009952807 scopus 로고    scopus 로고
    • Spontaneous cancer regression: Implication for fluctuation
    • Roy P, DD Majumder and J Biswas, Spontaneous cancer regression: implication for fluctuation Indian J. Phys. 73B (1999) 777
    • (1999) Indian J. Phys. , vol.73 B , pp. 777
    • Roy, P.D.1    Majumder, D.2    Biswas, J.3
  • 65
    • 32744472175 scopus 로고    scopus 로고
    • Biological parallelism in spontaneous remission of tumor and neurogranuloma
    • Roy P and J Biswas, Biological parallelism in spontaneous remission of tumor and neurogranuloma Tumor Biol. (1996)
    • (1996) Tumor Biol
    • Roy, P.1    Biswas, J.2
  • 66
    • 16344381707 scopus 로고    scopus 로고
    • Application of petri net theory for model ling and validation of the sucrose breakdown pathway in the potato tuber
    • Koch 1, BH Junker and M Heiner Application of Petri net theory for model ling and validation of the sucrose breakdown pathway in the potato tuber Bioinformalics 21 (2005) 1219
    • (2005) Bioinformalics , vol.21 , pp. 1219
    • Koch, L.1    Junker, B.H.2    Heiner, M.3
  • 67
    • 0345170901 scopus 로고    scopus 로고
    • Quantitative petri net model of gene regulated metabolic networks in the cell
    • Chen M and R Hofestadt, Quantitative Petri net model of gene regulated metabolic networks in the cell In Silico Biol 3 (2003) 347
    • (2003) Silico Biol , vol.3 , pp. 347
    • Chen, M.1    Hofestadt, R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.