-
1
-
-
77949450152
-
Antidepressants are a rational complementary therapy for the treatment of Alzheimer's disease
-
Aboukhatwa M., Dosanjh L., Luo Y. Antidepressants are a rational complementary therapy for the treatment of Alzheimer's disease. Mol. Neurodegener. 2010, 5:10.
-
(2010)
Mol. Neurodegener.
, vol.5
, pp. 10
-
-
Aboukhatwa, M.1
Dosanjh, L.2
Luo, Y.3
-
2
-
-
0023183875
-
Evidence for a possible functional interaction between serotonergic and cholinergic mechanisms in memory retrieval
-
Altman H.J., Stone W.S., Ogren S.O. Evidence for a possible functional interaction between serotonergic and cholinergic mechanisms in memory retrieval. Behav. Neural Biol. 1987, 48(1):49-62.
-
(1987)
Behav. Neural Biol.
, vol.48
, Issue.1
, pp. 49-62
-
-
Altman, H.J.1
Stone, W.S.2
Ogren, S.O.3
-
4
-
-
0016063911
-
The genetics of Caenorhabditis elegans
-
Brenner S. The genetics of Caenorhabditis elegans. Genetics 1974, 77(1):71-94.
-
(1974)
Genetics
, vol.77
, Issue.1
, pp. 71-94
-
-
Brenner, S.1
-
5
-
-
33646846111
-
Clinical effects of pharmacological variations in selective serotonin reuptake inhibitors: an overview
-
Carrasco J.L., Sandner C. Clinical effects of pharmacological variations in selective serotonin reuptake inhibitors: an overview. Int. J. Clin. Pract. 2005, 59(12):1428-1434.
-
(2005)
Int. J. Clin. Pract.
, vol.59
, Issue.12
, pp. 1428-1434
-
-
Carrasco, J.L.1
Sandner, C.2
-
6
-
-
77955920014
-
Imipramine, in part through TNF-{alpha} inhibition, prevents cognitive decline and A{beta} accumulation in a mouse model of Alzheimer's disease
-
Chavant F., Deguil J., Pain S., Ingrand I., Milin S., Fauconneau B., Perault M.C., Lafay-Chebassier C. Imipramine, in part through TNF-{alpha} inhibition, prevents cognitive decline and A{beta} accumulation in a mouse model of Alzheimer's disease. J. Pharmacol. Exp. Ther 2009.
-
(2009)
J. Pharmacol. Exp. Ther
-
-
Chavant, F.1
Deguil, J.2
Pain, S.3
Ingrand, I.4
Milin, S.5
Fauconneau, B.6
Perault, M.C.7
Lafay-Chebassier, C.8
-
7
-
-
62649115914
-
Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription
-
Chen Y., Zhou K., Wang R., Liu Y., Kwak Y.D., Ma T., Thompson R.C., Zhao Y., Smith L., Gasparini L., Luo Z., Xu H., Liao F.F. Antidiabetic drug metformin (GlucophageR) increases biogenesis of Alzheimer's amyloid peptides via up-regulating BACE1 transcription. Proc. Natl. Acad. Sci. U. S. A. 2009, 106(10):3907-3912.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, Issue.10
, pp. 3907-3912
-
-
Chen, Y.1
Zhou, K.2
Wang, R.3
Liu, Y.4
Kwak, Y.D.5
Ma, T.6
Thompson, R.C.7
Zhao, Y.8
Smith, L.9
Gasparini, L.10
Luo, Z.11
Xu, H.12
Liao, F.F.13
-
8
-
-
33748792821
-
Opposing activities protect against age-onset proteotoxicity
-
Cohen E., Bieschke J., Perciavalle R.M., Kelly J.W., Dillin A. Opposing activities protect against age-onset proteotoxicity. Science 2006, 313(5793):1604-1610.
-
(2006)
Science
, vol.313
, Issue.5793
, pp. 1604-1610
-
-
Cohen, E.1
Bieschke, J.2
Perciavalle, R.M.3
Kelly, J.W.4
Dillin, A.5
-
9
-
-
52449086907
-
The insulin paradox: aging, proteotoxicity and neurodegeneration
-
Cohen E., Dillin A. The insulin paradox: aging, proteotoxicity and neurodegeneration. Nat. Rev. Neurosci. 2008, 9(10):759-767.
-
(2008)
Nat. Rev. Neurosci.
, vol.9
, Issue.10
, pp. 759-767
-
-
Cohen, E.1
Dillin, A.2
-
10
-
-
33845577779
-
The role of insulin and neurotrophic factor signaling in brain aging and Alzheimer's disease
-
Cole G.M., Frautschy S.A. The role of insulin and neurotrophic factor signaling in brain aging and Alzheimer's disease. Exp. Gerontol. 2007, 42(1-2):10-21.
-
(2007)
Exp. Gerontol.
, vol.42
, Issue.1-2
, pp. 10-21
-
-
Cole, G.M.1
Frautschy, S.A.2
-
11
-
-
34147173277
-
Insulin resistance and Alzheimer's disease pathogenesis: potential mechanisms and implications for treatment
-
Craft S. Insulin resistance and Alzheimer's disease pathogenesis: potential mechanisms and implications for treatment. Curr. Alzheimer Res. 2007, 4(2):147-152.
-
(2007)
Curr. Alzheimer Res.
, vol.4
, Issue.2
, pp. 147-152
-
-
Craft, S.1
-
12
-
-
0038177803
-
Insulin dose-response effects on memory and plasma amyloid precursor protein in Alzheimer's disease: interactions with apolipoprotein E genotype
-
Craft S., Asthana S., Cook D.G., Baker L.D., Cherrier M., Purganan K., Wait C., Petrova A., Latendresse S., Watson G.S., Newcomer J.W., Schellenberg G.D., Krohn A.J. Insulin dose-response effects on memory and plasma amyloid precursor protein in Alzheimer's disease: interactions with apolipoprotein E genotype. Psychoneuroendocrinology 2003, 28(6):809-822.
-
(2003)
Psychoneuroendocrinology
, vol.28
, Issue.6
, pp. 809-822
-
-
Craft, S.1
Asthana, S.2
Cook, D.G.3
Baker, L.D.4
Cherrier, M.5
Purganan, K.6
Wait, C.7
Petrova, A.8
Latendresse, S.9
Watson, G.S.10
Newcomer, J.W.11
Schellenberg, G.D.12
Krohn, A.J.13
-
13
-
-
3042857903
-
Alzheimer's disease
-
Cummings J.L. Alzheimer's disease. N. Engl. J. Med. 2004, 351(1):56-67.
-
(2004)
N. Engl. J. Med.
, vol.351
, Issue.1
, pp. 56-67
-
-
Cummings, J.L.1
-
14
-
-
0027438026
-
Antidepressive agents and memory
-
Danion J.M. Encephale 1993, 19(Spec No 2):417-422.
-
(1993)
Encephale
, vol.19
, Issue.SPEC NO 2
, pp. 417-422
-
-
Danion, J.M.1
-
15
-
-
65649125633
-
Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression
-
David D.J., Samuels B.A., Rainer Q., Wang J.W., Marsteller D., Mendez I., Drew M., Craig D.A., Guiard B.P., Guilloux J.P., Artymyshyn R.P., Gardier A.M., Gerald C., Antonijevic I.A., Leonardo E.D., Hen R. Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression. Neuron 2009, 62(4):479-493.
-
(2009)
Neuron
, vol.62
, Issue.4
, pp. 479-493
-
-
David, D.J.1
Samuels, B.A.2
Rainer, Q.3
Wang, J.W.4
Marsteller, D.5
Mendez, I.6
Drew, M.7
Craig, D.A.8
Guiard, B.P.9
Guilloux, J.P.10
Artymyshyn, R.P.11
Gardier, A.M.12
Gerald, C.13
Antonijevic, I.A.14
Leonardo, E.D.15
Hen, R.16
-
16
-
-
60549084867
-
Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Abeta oligomers
-
De Felice F.G., Vieira M.N., Bomfim T.R., Decker H., Velasco P.T., Lambert M.P., Viola K.L., Zhao W.Q., Ferreira S.T., Klein W.L. Protection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Abeta oligomers. Proc. Natl. Acad. Sci. U. S. A. 2009, 106(6):1971-1976.
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, Issue.6
, pp. 1971-1976
-
-
De Felice, F.G.1
Vieira, M.N.2
Bomfim, T.R.3
Decker, H.4
Velasco, P.T.5
Lambert, M.P.6
Viola, K.L.7
Zhao, W.Q.8
Ferreira, S.T.9
Klein, W.L.10
-
17
-
-
17444408824
-
Serotonin (5HT), fluoxetine, imipramine and dopamine target distinct 5HT receptor signaling to modulate Caenorhabditis elegans egg-laying behavior
-
Dempsey C.M., Mackenzie S.M., Gargus A., Blanco G., Sze J.Y. Serotonin (5HT), fluoxetine, imipramine and dopamine target distinct 5HT receptor signaling to modulate Caenorhabditis elegans egg-laying behavior. Genetics 2005, 169(3):1425-1436.
-
(2005)
Genetics
, vol.169
, Issue.3
, pp. 1425-1436
-
-
Dempsey, C.M.1
Mackenzie, S.M.2
Gargus, A.3
Blanco, G.4
Sze, J.Y.5
-
18
-
-
0031681434
-
Novel therapeutic approaches beyond the serotonin receptor
-
Duman R.S. Novel therapeutic approaches beyond the serotonin receptor. Biol. Psychiatry 1998, 44(5):324-335.
-
(1998)
Biol. Psychiatry
, vol.44
, Issue.5
, pp. 324-335
-
-
Duman, R.S.1
-
19
-
-
0033524413
-
Polyglutamine-mediated dysfunction and apoptotic death of a Caenorhabditis elegans sensory neuron
-
Faber P.W., Alter J.R., MacDonald M.E., Hart A.C. Polyglutamine-mediated dysfunction and apoptotic death of a Caenorhabditis elegans sensory neuron. Proc. Natl. Acad. Sci. U. S. A. 1999, 96(1):179-184.
-
(1999)
Proc. Natl. Acad. Sci. U. S. A.
, vol.96
, Issue.1
, pp. 179-184
-
-
Faber, P.W.1
Alter, J.R.2
MacDonald, M.E.3
Hart, A.C.4
-
20
-
-
0842325104
-
A randomized, placebo-controlled study of the efficacy and safety of sertraline in the treatment of the behavioral manifestations of Alzheimer's disease in outpatients treated with donepezil
-
Finkel S.I., Mintzer J.E., Dysken M., Krishnan K.R., Burt T., McRae T. A randomized, placebo-controlled study of the efficacy and safety of sertraline in the treatment of the behavioral manifestations of Alzheimer's disease in outpatients treated with donepezil. Int. J. Geriatr. Psychiatry 2004, 19(1):9-18.
-
(2004)
Int. J. Geriatr. Psychiatry
, vol.19
, Issue.1
, pp. 9-18
-
-
Finkel, S.I.1
Mintzer, J.E.2
Dysken, M.3
Krishnan, K.R.4
Burt, T.5
McRae, T.6
-
21
-
-
70349672704
-
Neuronal IGF-1 resistance reduces Abeta accumulation and protects against premature death in a model of Alzheimer's disease
-
Freude S., Hettich M.M., Schumann C., Stohr O., Koch L., Kohler C., Udelhoven M., Leeser U., Muller M., Kubota N., Kadowaki T., Krone W., Schroder H., Bruning J.C., Schubert M. Neuronal IGF-1 resistance reduces Abeta accumulation and protects against premature death in a model of Alzheimer's disease. Faseb J. 2009, 23(10):3315-3324.
-
(2009)
Faseb J.
, vol.23
, Issue.10
, pp. 3315-3324
-
-
Freude, S.1
Hettich, M.M.2
Schumann, C.3
Stohr, O.4
Koch, L.5
Kohler, C.6
Udelhoven, M.7
Leeser, U.8
Muller, M.9
Kubota, N.10
Kadowaki, T.11
Krone, W.12
Schroder, H.13
Bruning, J.C.14
Schubert, M.15
-
22
-
-
0034129941
-
Depression and risk of cognitive decline and Alzheimer's disease. Results of two prospective community-based studies in The Netherlands
-
Geerlings M.I., Schoevers R.A., Beekman A.T., Jonker C., Deeg D.J., Schmand B., Ader H.J., Bouter L.M., Van Tilburg W. Depression and risk of cognitive decline and Alzheimer's disease. Results of two prospective community-based studies in The Netherlands. Br. J. Psychiatry 2000, 176:568-575.
-
(2000)
Br. J. Psychiatry
, vol.176
, pp. 568-575
-
-
Geerlings, M.I.1
Schoevers, R.A.2
Beekman, A.T.3
Jonker, C.4
Deeg, D.J.5
Schmand, B.6
Ader, H.J.7
Bouter, L.M.8
Van Tilburg, W.9
-
23
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics
-
Hardy J., Selkoe D.J. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science 2002, 297(5580):353-356.
-
(2002)
Science
, vol.297
, Issue.5580
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
24
-
-
0033937168
-
Adult brain neurogenesis and psychiatry: a novel theory of depression
-
Jacobs B.L., Praag H., Gage F.H. Adult brain neurogenesis and psychiatry: a novel theory of depression. Mol. Psychiatry 2000, 5(3):262-269.
-
(2000)
Mol. Psychiatry
, vol.5
, Issue.3
, pp. 262-269
-
-
Jacobs, B.L.1
Praag, H.2
Gage, F.H.3
-
25
-
-
33745223646
-
Finding function in novel targets: C. elegans as a model organism
-
Kaletta T., Hengartner M.O. Finding function in novel targets: C. elegans as a model organism. Nat. Rev. Drug Discov. 2006, 5(5):387-398.
-
(2006)
Nat. Rev. Drug Discov.
, vol.5
, Issue.5
, pp. 387-398
-
-
Kaletta, T.1
Hengartner, M.O.2
-
26
-
-
33847182471
-
Haplotypes in the human Foxo1a and Foxo3a genes; impact on disease and mortality at old age
-
Kuningas M., Magi R., Westendorp R.G., Slagboom P.E., Remm M., van Heemst D. Haplotypes in the human Foxo1a and Foxo3a genes; impact on disease and mortality at old age. Eur. J. Hum. Genet. 2007, 15(3):294-301.
-
(2007)
Eur. J. Hum. Genet.
, vol.15
, Issue.3
, pp. 294-301
-
-
Kuningas, M.1
Magi, R.2
Westendorp, R.G.3
Slagboom, P.E.4
Remm, M.5
van Heemst, D.6
-
27
-
-
20844458090
-
Synaptic targeting by Alzheimer's-related amyloid beta oligomers
-
Lacor P.N., Buniel M.C., Chang L., Fernandez S.J., Gong Y., Viola K.L., Lambert M.P., Velasco P.T., Bigio E.H., Finch C.E., Krafft G.A., Klein W.L. Synaptic targeting by Alzheimer's-related amyloid beta oligomers. J. Neurosci. 2004, 24(45):10191-10200.
-
(2004)
J. Neurosci.
, vol.24
, Issue.45
, pp. 10191-10200
-
-
Lacor, P.N.1
Buniel, M.C.2
Chang, L.3
Fernandez, S.J.4
Gong, Y.5
Viola, K.L.6
Lambert, M.P.7
Velasco, P.T.8
Bigio, E.H.9
Finch, C.E.10
Krafft, G.A.11
Klein, W.L.12
-
28
-
-
33846633336
-
Abeta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease
-
Lacor P.N., Buniel M.C., Furlow P.W., Clemente A.S., Velasco P.T., Wood M., Viola K.L., Klein W.L. Abeta oligomer-induced aberrations in synapse composition, shape, and density provide a molecular basis for loss of connectivity in Alzheimer's disease. J. Neurosci. 2007, 27(4):796-807.
-
(2007)
J. Neurosci.
, vol.27
, Issue.4
, pp. 796-807
-
-
Lacor, P.N.1
Buniel, M.C.2
Furlow, P.W.3
Clemente, A.S.4
Velasco, P.T.5
Wood, M.6
Viola, K.L.7
Klein, W.L.8
-
29
-
-
0037008002
-
Postmortem serotoninergic correlates of cognitive decline in Alzheimer's disease
-
Lai M.K., Tsang S.W., Francis P.T., Keene J., Hope T., Esiri M.M., Spence I., Chen C.P. Postmortem serotoninergic correlates of cognitive decline in Alzheimer's disease. Neuroreport 2002, 13(9):1175-1178.
-
(2002)
Neuroreport
, vol.13
, Issue.9
, pp. 1175-1178
-
-
Lai, M.K.1
Tsang, S.W.2
Francis, P.T.3
Keene, J.4
Hope, T.5
Esiri, M.M.6
Spence, I.7
Chen, C.P.8
-
30
-
-
0037971209
-
Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human alpha-synuclein
-
Lakso M., Vartiainen S., Moilanen A.M., Sirvio J., Thomas J.H., Nass R., Blakely R.D., Wong G. Dopaminergic neuronal loss and motor deficits in Caenorhabditis elegans overexpressing human alpha-synuclein. J. Neurochem. 2003, 86(1):165-172.
-
(2003)
J. Neurochem.
, vol.86
, Issue.1
, pp. 165-172
-
-
Lakso, M.1
Vartiainen, S.2
Moilanen, A.M.3
Sirvio, J.4
Thomas, J.H.5
Nass, R.6
Blakely, R.D.7
Wong, G.8
-
31
-
-
11544279355
-
Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins
-
Lambert M.P., Barlow A.K., Chromy B.A., Edwards C., Freed R., Liosatos M., Morgan T.E., Rozovsky I., Trommer B., Viola K.L., Wals P., Zhang C., Finch C.E., Krafft G.A., Klein W.L. Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins. Proc. Natl. Acad. Sci. U. S. A. 1998, 95(11):6448-6453.
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, Issue.11
, pp. 6448-6453
-
-
Lambert, M.P.1
Barlow, A.K.2
Chromy, B.A.3
Edwards, C.4
Freed, R.5
Liosatos, M.6
Morgan, T.E.7
Rozovsky, I.8
Trommer, B.9
Viola, K.L.10
Wals, P.11
Zhang, C.12
Finch, C.E.13
Krafft, G.A.14
Klein, W.L.15
-
32
-
-
0141832613
-
Depression in Alzheimer's disease: heterogeneity and related issues
-
Lee H.B., Lyketsos C.G. Depression in Alzheimer's disease: heterogeneity and related issues. Biol. Psychiatry 2003, 54(3):353-362.
-
(2003)
Biol. Psychiatry
, vol.54
, Issue.3
, pp. 353-362
-
-
Lee, H.B.1
Lyketsos, C.G.2
-
33
-
-
0028981288
-
Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans
-
Link C.D. Expression of human beta-amyloid peptide in transgenic Caenorhabditis elegans. Proc. Natl. Acad. Sci. U. S. A. 1995, 92(20):9368-9372.
-
(1995)
Proc. Natl. Acad. Sci. U. S. A.
, vol.92
, Issue.20
, pp. 9368-9372
-
-
Link, C.D.1
-
34
-
-
0035975702
-
Transgenic invertebrate models of age-associated neurodegenerative diseases
-
Link C.D. Transgenic invertebrate models of age-associated neurodegenerative diseases. Mech. Ageing Dev. 2001, 122(14):1639-1649.
-
(2001)
Mech. Ageing Dev.
, vol.122
, Issue.14
, pp. 1639-1649
-
-
Link, C.D.1
-
35
-
-
33751397131
-
C. elegans models of age-associated neurodegenerative diseases: lessons from transgenic worm models of Alzheimer's disease
-
Link C.D. C. elegans models of age-associated neurodegenerative diseases: lessons from transgenic worm models of Alzheimer's disease. Exp. Gerontol. 2006, 41(10):1007-1013.
-
(2006)
Exp. Gerontol.
, vol.41
, Issue.10
, pp. 1007-1013
-
-
Link, C.D.1
-
36
-
-
0034671366
-
Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus
-
Malberg J.E., Eisch A.J., Nestler E.J., Duman R.S. Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J. Neurosci. 2000, 20(24):9104-9110.
-
(2000)
J. Neurosci.
, vol.20
, Issue.24
, pp. 9104-9110
-
-
Malberg, J.E.1
Eisch, A.J.2
Nestler, E.J.3
Duman, R.S.4
-
37
-
-
0032590054
-
Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease
-
McLean C.A., Cherny R.A., Fraser F.W., Fuller S.J., Smith M.J., Beyreuther K., Bush A.I., Masters C.L. Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease. Ann. Neurol. 1999, 46(6):860-866.
-
(1999)
Ann. Neurol.
, vol.46
, Issue.6
, pp. 860-866
-
-
McLean, C.A.1
Cherny, R.A.2
Fraser, F.W.3
Fuller, S.J.4
Smith, M.J.5
Beyreuther, K.6
Bush, A.I.7
Masters, C.L.8
-
38
-
-
34548699679
-
Does serotonin augmentation have any effect on cognition and activities of daily living in Alzheimer's dementia? A double-blind, placebo-controlled clinical trial
-
Mowla A., Mosavinasab M., Haghshenas H., Haghighi A.B. Does serotonin augmentation have any effect on cognition and activities of daily living in Alzheimer's dementia? A double-blind, placebo-controlled clinical trial. J. Clin. Psychopharmacol. 2007, 27(5):484-487.
-
(2007)
J. Clin. Psychopharmacol.
, vol.27
, Issue.5
, pp. 484-487
-
-
Mowla, A.1
Mosavinasab, M.2
Haghshenas, H.3
Haghighi, A.B.4
-
39
-
-
33846222301
-
Does fluoxetine have any effect on the cognition of patients with mild cognitive impairment? A double-blind, placebo-controlled, clinical trial
-
Mowla A., Mosavinasab M., Pani A. Does fluoxetine have any effect on the cognition of patients with mild cognitive impairment? A double-blind, placebo-controlled, clinical trial. J. Clin. Psychopharmacol. 2007, 27(1):67-70.
-
(2007)
J. Clin. Psychopharmacol.
, vol.27
, Issue.1
, pp. 67-70
-
-
Mowla, A.1
Mosavinasab, M.2
Pani, A.3
-
41
-
-
34447632659
-
Serotonin receptors antagonistically modulate Caenorhabditis elegans longevity
-
Murakami H., Murakami S. Serotonin receptors antagonistically modulate Caenorhabditis elegans longevity. Aging Cell 2007, 6(4):483-488.
-
(2007)
Aging Cell
, vol.6
, Issue.4
, pp. 483-488
-
-
Murakami, H.1
Murakami, S.2
-
42
-
-
33751430460
-
The search for DAF-16/FOXO transcriptional targets: approaches and discoveries
-
Murphy C.T. The search for DAF-16/FOXO transcriptional targets: approaches and discoveries. Exp. Gerontol. 2006, 41(10):910-921.
-
(2006)
Exp. Gerontol.
, vol.41
, Issue.10
, pp. 910-921
-
-
Murphy, C.T.1
-
43
-
-
0037022668
-
Neurotoxin-induced degeneration of dopamine neurons in Caenorhabditis elegans
-
Nass R., Hall D.H., Miller D.M., Blakely R.D. Neurotoxin-induced degeneration of dopamine neurons in Caenorhabditis elegans. Proc. Natl. Acad. Sci. U. S. A. 2002, 99(5):3264-3269.
-
(2002)
Proc. Natl. Acad. Sci. U. S. A.
, vol.99
, Issue.5
, pp. 3264-3269
-
-
Nass, R.1
Hall, D.H.2
Miller, D.M.3
Blakely, R.D.4
-
44
-
-
34247211763
-
Prophylactic treatment with paroxetine ameliorates behavioral deficits and retards the development of amyloid and tau pathologies in 3xTgAD mice
-
Nelson R.L., Guo Z., Halagappa V.M., Pearson M., Gray A.J., Matsuoka Y., Brown M., Martin B., Iyun T., Maudsley S., Clark R.F., Mattson M.P. Prophylactic treatment with paroxetine ameliorates behavioral deficits and retards the development of amyloid and tau pathologies in 3xTgAD mice. Exp. Neurol. 2007, 205(1):166-176.
-
(2007)
Exp. Neurol.
, vol.205
, Issue.1
, pp. 166-176
-
-
Nelson, R.L.1
Guo, Z.2
Halagappa, V.M.3
Pearson, M.4
Gray, A.J.5
Matsuoka, Y.6
Brown, M.7
Martin, B.8
Iyun, T.9
Maudsley, S.10
Clark, R.F.11
Mattson, M.P.12
-
45
-
-
0025244327
-
The clinical efficacy of citalopram in treatment of emotional disturbances in dementia disorders. A Nordic multicentre study
-
Nyth A.L., Gottfries C.G. The clinical efficacy of citalopram in treatment of emotional disturbances in dementia disorders. A Nordic multicentre study. Br. J. Psychiatry 1990, 157:894-901.
-
(1990)
Br. J. Psychiatry
, vol.157
, pp. 894-901
-
-
Nyth, A.L.1
Gottfries, C.G.2
-
46
-
-
0026702734
-
A controlled multicenter clinical study of citalopram and placebo in elderly depressed patients with and without concomitant dementia
-
Nyth A.L., Gottfries C.G., Lyby K., Smedegaard-Andersen L., Gylding-Sabroe J., Kristensen M., Refsum H.E., Ofsti E., Eriksson S., Syversen S. A controlled multicenter clinical study of citalopram and placebo in elderly depressed patients with and without concomitant dementia. Acta Psychiatr. Scand. 1992, 86(2):138-145.
-
(1992)
Acta Psychiatr. Scand.
, vol.86
, Issue.2
, pp. 138-145
-
-
Nyth, A.L.1
Gottfries, C.G.2
Lyby, K.3
Smedegaard-Andersen, L.4
Gylding-Sabroe, J.5
Kristensen, M.6
Refsum, H.E.7
Ofsti, E.8
Eriksson, S.9
Syversen, S.10
-
47
-
-
0035450364
-
Second-generation SSRIs: human monoamine transporter binding profile of escitalopram and R-fluoxetine
-
Owens M.J., Knight D.L., Nemeroff C.B. Second-generation SSRIs: human monoamine transporter binding profile of escitalopram and R-fluoxetine. Biol. Psychiatry 2001, 50(5):345-350.
-
(2001)
Biol. Psychiatry
, vol.50
, Issue.5
, pp. 345-350
-
-
Owens, M.J.1
Knight, D.L.2
Nemeroff, C.B.3
-
48
-
-
0002115642
-
Differential effects of fluoxetine and citalopram treatments on serotonin 5-HT(2C) receptor occupancy in rat brain
-
Palvimaki E.P., Kuoppamaki M., Syvalahti E., Hietala J. Differential effects of fluoxetine and citalopram treatments on serotonin 5-HT(2C) receptor occupancy in rat brain. Int. J. Neuropsychopharmacol. 1999, 2(2):95-99.
-
(1999)
Int. J. Neuropsychopharmacol.
, vol.2
, Issue.2
, pp. 95-99
-
-
Palvimaki, E.P.1
Kuoppamaki, M.2
Syvalahti, E.3
Hietala, J.4
-
49
-
-
2042492543
-
Antipsychotics and selective serotonin reuptake inhibitors for the treatment of behavioral disturbances in dementia of the Alzheimer type
-
Pollock B.G., Rosen J., Mulsant B.H. Antipsychotics and selective serotonin reuptake inhibitors for the treatment of behavioral disturbances in dementia of the Alzheimer type. Consultant Pharm. 1999, 11:1251-1258.
-
(1999)
Consultant Pharm.
, vol.11
, pp. 1251-1258
-
-
Pollock, B.G.1
Rosen, J.2
Mulsant, B.H.3
-
50
-
-
41049111771
-
Effectiveness of cholinesterase inhibitors and memantine for treating dementia: evidence review for a clinical practice guideline
-
Raina P., Santaguida P., Ismaila A., Patterson C., Cowan D., Levine M., Booker L., Oremus M. Effectiveness of cholinesterase inhibitors and memantine for treating dementia: evidence review for a clinical practice guideline. Ann. Intern. Med. 2008, 148(5):379-397.
-
(2008)
Ann. Intern. Med.
, vol.148
, Issue.5
, pp. 379-397
-
-
Raina, P.1
Santaguida, P.2
Ismaila, A.3
Patterson, C.4
Cowan, D.5
Levine, M.6
Booker, L.7
Oremus, M.8
-
51
-
-
49249118742
-
Neurotoxic effect of oligomeric and fibrillar species of amyloid-beta peptide 1-42: involvement of endoplasmic reticulum calcium release in oligomer-induced cell death
-
Resende R., Ferreiro E., Pereira C., Resende de Oliveira C. Neurotoxic effect of oligomeric and fibrillar species of amyloid-beta peptide 1-42: involvement of endoplasmic reticulum calcium release in oligomer-induced cell death. Neuroscience 2008, 155(3):725-737.
-
(2008)
Neuroscience
, vol.155
, Issue.3
, pp. 725-737
-
-
Resende, R.1
Ferreiro, E.2
Pereira, C.3
Resende de Oliveira, C.4
-
52
-
-
75149138979
-
Efficacy of SSRIs on cognition of Alzheimer's disease patients treated with cholinesterase inhibitors
-
Rozzini L., Chilovi B.V., Conti M., Bertoletti E., Zanetti M., Trabucchi M., Padovani A. Efficacy of SSRIs on cognition of Alzheimer's disease patients treated with cholinesterase inhibitors. Int. Psychogeriatr. 2010, 22(1):114-119.
-
(2010)
Int. Psychogeriatr.
, vol.22
, Issue.1
, pp. 114-119
-
-
Rozzini, L.1
Chilovi, B.V.2
Conti, M.3
Bertoletti, E.4
Zanetti, M.5
Trabucchi, M.6
Padovani, A.7
-
53
-
-
33745114656
-
Recent aging research in Caenorhabditis elegans
-
Schaffitzel E., Hertweck M. Recent aging research in Caenorhabditis elegans. Exp. Gerontol. 2006, 41(6):557-563.
-
(2006)
Exp. Gerontol.
, vol.41
, Issue.6
, pp. 557-563
-
-
Schaffitzel, E.1
Hertweck, M.2
-
54
-
-
33745762580
-
Serotonin and human cognitive performance
-
Schmitt J.A., Wingen M., Ramaekers J.G., Evers E.A., Riedel W.J. Serotonin and human cognitive performance. Curr. Pharm. Des. 2006, 12(20):2473-2486.
-
(2006)
Curr. Pharm. Des.
, vol.12
, Issue.20
, pp. 2473-2486
-
-
Schmitt, J.A.1
Wingen, M.2
Ramaekers, J.G.3
Evers, E.A.4
Riedel, W.J.5
-
55
-
-
34547760490
-
Treatment of Alzheimer's disease across the spectrum of severity
-
Shah S., Reichman W.E. Treatment of Alzheimer's disease across the spectrum of severity. Clin. Interv. Aging 2006, 1(2):131-142.
-
(2006)
Clin. Interv. Aging
, vol.1
, Issue.2
, pp. 131-142
-
-
Shah, S.1
Reichman, W.E.2
-
56
-
-
34248366979
-
Efficacy and safety of antidepressants for treatment of depression in Alzheimer's disease: a metaanalysis
-
Thompson S., Herrmann N., Rapoport M.J., Lanctot K.L. Efficacy and safety of antidepressants for treatment of depression in Alzheimer's disease: a metaanalysis. Can. J. Psychiatry 2007, 52(4):248-255.
-
(2007)
Can. J. Psychiatry
, vol.52
, Issue.4
, pp. 248-255
-
-
Thompson, S.1
Herrmann, N.2
Rapoport, M.J.3
Lanctot, K.L.4
-
57
-
-
36348935683
-
Soluble Abeta inhibits specific signal transduction cascades common to the insulin receptor pathway
-
Townsend M., Mehta T., Selkoe D.J. Soluble Abeta inhibits specific signal transduction cascades common to the insulin receptor pathway. J. Biol. Chem. 2007, 282(46):33305-33312.
-
(2007)
J. Biol. Chem.
, vol.282
, Issue.46
, pp. 33305-33312
-
-
Townsend, M.1
Mehta, T.2
Selkoe, D.J.3
-
58
-
-
44049102976
-
Current and future therapy in Alzheimer's disease
-
van Marum R.J. Current and future therapy in Alzheimer's disease. Fundam. Clin. Pharmacol. 2008, 22(3):265-274.
-
(2008)
Fundam. Clin. Pharmacol.
, vol.22
, Issue.3
, pp. 265-274
-
-
van Marum, R.J.1
-
59
-
-
50649101095
-
Puzzles, promises and a cure for ageing
-
Vijg J., Campisi J. Puzzles, promises and a cure for ageing. Nature 2008, 454(7208):1065-1071.
-
(2008)
Nature
, vol.454
, Issue.7208
, pp. 1065-1071
-
-
Vijg, J.1
Campisi, J.2
-
60
-
-
0034022656
-
Distinction between preclinical Alzheimer's disease and depression
-
Visser P.J., Verhey F.R., Ponds R.W., Kester A., Jolles J. Distinction between preclinical Alzheimer's disease and depression. J. Am. Geriatr. Soc. 2000, 48(5):479-484.
-
(2000)
J. Am. Geriatr. Soc.
, vol.48
, Issue.5
, pp. 479-484
-
-
Visser, P.J.1
Verhey, F.R.2
Ponds, R.W.3
Kester, A.4
Jolles, J.5
-
61
-
-
3042656636
-
Hippocampal volume, memory, and cortisol status in major depressive disorder: effects of treatment
-
Vythilingam M., Vermetten E., Anderson G.M., Luckenbaugh D., Anderson E.R., Snow J., Staib L.H., Charney D.S., Bremner J.D. Hippocampal volume, memory, and cortisol status in major depressive disorder: effects of treatment. Biol. Psychiatry 2004, 56(2):101-112.
-
(2004)
Biol. Psychiatry
, vol.56
, Issue.2
, pp. 101-112
-
-
Vythilingam, M.1
Vermetten, E.2
Anderson, G.M.3
Luckenbaugh, D.4
Anderson, E.R.5
Snow, J.6
Staib, L.H.7
Charney, D.S.8
Bremner, J.D.9
-
62
-
-
33644592598
-
Preserved cognition in patients with early Alzheimer disease and amnestic mild cognitive impairment during treatment with rosiglitazone: a preliminary study
-
Watson G.S., Cholerton B.A., Reger M.A., Baker L.D., Plymate S.R., Asthana S., Fishel M.A., Kulstad J.J., Green P.S., Cook D.G., Kahn S.E., Keeling M.L., Craft S. Preserved cognition in patients with early Alzheimer disease and amnestic mild cognitive impairment during treatment with rosiglitazone: a preliminary study. Am. J. Geriatr. Psychiatry 2005, 13(11):950-958.
-
(2005)
Am. J. Geriatr. Psychiatry
, vol.13
, Issue.11
, pp. 950-958
-
-
Watson, G.S.1
Cholerton, B.A.2
Reger, M.A.3
Baker, L.D.4
Plymate, S.R.5
Asthana, S.6
Fishel, M.A.7
Kulstad, J.J.8
Green, P.S.9
Cook, D.G.10
Kahn, S.E.11
Keeling, M.L.12
Craft, S.13
-
63
-
-
0031813997
-
Fluoxetine. A pharmacoeconomic review of its use in depression
-
Wilde M.I., Benfield P. Fluoxetine. A pharmacoeconomic review of its use in depression. Pharmacoeconomics 1998, 13(5 Pt 1):543-561.
-
(1998)
Pharmacoeconomics
, vol.13
, Issue.5 PART 1
, pp. 543-561
-
-
Wilde, M.I.1
Benfield, P.2
-
64
-
-
33845613251
-
Amyloid-beta-induced pathological behaviors are suppressed by Ginkgo biloba extract EGb 761 and ginkgolides in transgenic Caenorhabditis elegans
-
Wu Y., Wu Z., Butko P., Christen Y., Lambert M.P., Klein W.L., Link C.D., Luo Y. Amyloid-beta-induced pathological behaviors are suppressed by Ginkgo biloba extract EGb 761 and ginkgolides in transgenic Caenorhabditis elegans. J. Neurosci. 2006, 26(50):13102-13113.
-
(2006)
J. Neurosci.
, vol.26
, Issue.50
, pp. 13102-13113
-
-
Wu, Y.1
Wu, Z.2
Butko, P.3
Christen, Y.4
Lambert, M.P.5
Klein, W.L.6
Link, C.D.7
Luo, Y.8
-
65
-
-
38049110692
-
Amyloid beta oligomers induce impairment of neuronal insulin receptors
-
Zhao W.Q., De Felice F.G., Fernandez S., Chen H., Lambert M.P., Quon M.J., Krafft G.A., Klein W.L. Amyloid beta oligomers induce impairment of neuronal insulin receptors. Faseb J. 2008, 22(1):246-260.
-
(2008)
Faseb J.
, vol.22
, Issue.1
, pp. 246-260
-
-
Zhao, W.Q.1
De Felice, F.G.2
Fernandez, S.3
Chen, H.4
Lambert, M.P.5
Quon, M.J.6
Krafft, G.A.7
Klein, W.L.8
-
66
-
-
67650544970
-
Insulin receptor dysfunction impairs cellular clearance of neurotoxic oligomeric a{beta}
-
Zhao W.Q., Lacor P.N., Chen H., Lambert M.P., Quon M.J., Krafft G.A., Klein W.L. Insulin receptor dysfunction impairs cellular clearance of neurotoxic oligomeric a{beta}. J. Biol. Chem. 2009, 284(28):18742-18753.
-
(2009)
J. Biol. Chem.
, vol.284
, Issue.28
, pp. 18742-18753
-
-
Zhao, W.Q.1
Lacor, P.N.2
Chen, H.3
Lambert, M.P.4
Quon, M.J.5
Krafft, G.A.6
Klein, W.L.7
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