In vitro cytotoxicity of porous silicon microparticles: Effect of the particle concentration, surface chemistry and size

Acta Biomaterialia

Volumn 6, Issue 7, 2010, Pages 2721-2731

  Santos, Hélder A ^a   Riikonen, Joakim ^b   Salonen, Jarno ^c   Mäkilä, Ermei ^c   Heikkilä, Teemu ^c   Laaksonen, Timo ^a   Peltonen, Leena ^a   Lehto, Vesa Pekka ^b   Hirvonen, Jouni ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

^c UNIVERSITY OF TURKU   (Finland)

Author keywords

Caco 2 cells; Cytotoxicity; Microparticles; Oral drug delivery; Porous silicon

Indexed keywords

CELL DEATH; DRUG DELIVERY; PARTICLE SIZE; POROUS SILICON; SILICON COMPOUNDS; SURFACE CHEMISTRY; SURFACE TREATMENT;

CACO-2 CELLS; IN-VITRO; MESOPOROUS; MICRO PARTICLES; ORAL DRUG DELIVERY; PARTICLE-SIZE FRACTIONS; PARTICLES CONCENTRATION; PARTICLES SIZES; THERMALLY OXIDIZED; VITRO CYTOTOXICITIES;

CYTOTOXICITY;

ADENOSINE TRIPHOSPHATE; REACTIVE OXYGEN METABOLITE; SILICON;

APOPTOSIS; ARTICLE; CELL DAMAGE; CELL DEATH; CELL INTERACTION; CELL STRAIN CACO 2; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; IN VITRO STUDY; PARTICLE SIZE; POROSITY; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTY; CHEMISTRY; FLOW CYTOMETRY; METABOLISM;

ADENOSINE TRIPHOSPHATE; APOPTOSIS; CACO-2 CELLS; FLOW CYTOMETRY; HUMANS; MICROSCOPY, ELECTRON, SCANNING; PARTICLE SIZE; REACTIVE OXYGEN SPECIES; SILICON; SURFACE PROPERTIES;

EID: 77955907265     PISSN: 17427061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.actbio.2009.12.043     Document Type: Article

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