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Volumn 16, Issue 31, 2010, Pages 9563-9571

Synthesis of small molecules with high scaffold diversity: Exploitation of metathesis cascades in combination with inter-and intramolecular diels-alder reactions

(7) O'Leary Steele, Catherine a Pedersen, Palle J a James, Thomas a Lanyon Hogg, Thomas a Leach, Stuart a Hayes, Jerome b Nelson, Adam a

a UNIVERSITY OF LEEDS (United Kingdom)

b GLAXOSMITHKLINE (United Kingdom)

Author keywords

Cycloaddition; Diversity; Domino reactions; Metathesis; Molecular diversity; Oriented synthesis

Indexed keywords

DIVERSITY; DOMINO REACTIONS; METATHESIS; MOLECULAR DIVERSITY; ORIENTED SYNTHESIS;

COMPLEXATION; OLEFINS; REACTION KINETICS; SCAFFOLDS; SYNTHESIS (CHEMICAL);

CYCLOADDITION;

HETEROCYCLIC COMPOUND;

ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CYCLIZATION;

CYCLIZATION; HETEROCYCLIC COMPOUNDS; MOLECULAR STRUCTURE;

EID: 77955820975 PISSN: 09476539 EISSN: 15213765 Source Type: Journal
DOI: 10.1002/chem.201000707 Document Type: Article

Times cited : (32)

References (44)

1
- 33746156959
- a) G. V. Paolini, R. H. B. Shapland, W. P. van Hoorn, J. S. Mason, A. L. Hopkins, Nat. Biotechnol. 2006, 24, 805-815;
- (2006) Nat. Biotechnol. , vol.24 , pp. 805-815
- Paolini, G.V.¹ Shapland, R.H.B.² Van Hoorn, W.P.³ Mason, J.S.⁴ Hopkins, A.L.⁵

2
- 28444498830
- M. A. Koch, A. Schuffenhauer, M. Scheck, S. Wetzel, M. Casaulta, A. Odermatt, P. Ertl, H. Waldmann, Proc. Natl. Acad. Sci. USA 2005, 102, 17272-17277.
- (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 17272-17277
- Koch, M.A.¹ Schuffenhauer, A.² Scheck, M.³ Wetzel, S.⁴ Casaulta, M.⁵ Odermatt, A.⁶ Ertl, P.⁷ Waldmann, H.⁸

3
- 33746047675
- A. Nören-Müller, I. Reis-Corrêa, H. Prinz, C. Rosenbaum, K. Saxena, H. J. Schwalbe, D. Vestweber, G. Cagna, S. Schunk, O. Schwarz, H. Schiewe, H. Waldmann, Proc. Natl. Acad. Sci. USA 2006, 103, 10606-10611.
- (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 10606-10611
- Nören-Müller, A.¹ Reis-Corrêa, I.² Prinz, H.³ Rosenbaum, C.⁴ Saxena, K.⁵ Schwalbe, H.J.⁶ Vestweber, D.⁷ Cagna, G.⁸ Schunk, S.⁹ Schwarz, O.¹⁰ Schiewe, H.¹¹ Waldmann, H.¹²

4
- 58249110426
- H. Waldmann, Nat. Chem. Biol. 2009, 5, 76-77.
- (2009) Nat. Chem. Biol. , vol.5 , pp. 76-77
- Waldmann, H.¹

5
- 33746740077
- a) P. Ertl, S. Jelfs, J. Mühlbacher, A. Schuffenhauer, P. Selzer, J. Med. Chem. 2006, 49, 4568;
- (2006) J. Med. Chem. , vol.49 , pp. 4568
- Ertl, P.¹ Jelfs, S.² Mühlbacher, J.³ Schuffenhauer, A.⁴ Selzer, P.⁵

6
- 34447517392
- b) A. A. Shelat, R. K. Guy, Nat. Chem. Biol. 2007, 3, 442-446;
- (2007) Nat. Chem. Biol. , vol.3 , pp. 442-446
- Shelat, A.A.¹ Guy, R.K.²

7
- 77249139237
- c) Y. Hu, A. M. Wassermann, E. Lounkine, J. Bajorath, J. Med. Chem. 2010, 53, 752-758;
- (2010) J. Med. Chem. , vol.53 , pp. 752-758
- Hu, Y.¹ Wassermann, A.M.² Lounkine, E.³ Bajorath, J.⁴

8
- 67650299761
- d) J. Hert, J. J. Irwin, C. Laggner, M. J. Keiser, B. K. Schoichet, Nat. Chem. Biol. 2009, 5, 479-483;
- (2009) Nat. Chem. Biol. , vol.5 , pp. 479-483
- Hert, J.¹ Irwin, J.J.² Laggner, C.³ Keiser, M.J.⁴ Schoichet, B.K.⁵

9
- 68049098031
- e) S. Wetzel, K. Klein, S. Renner, D. Rauh, T. I Oprea, P. Mutzel, H. Waldman, Nat. Chem. Biol. 2009, 5, 581-583.
- (2009) Nat. Chem. Biol. , vol.5 , pp. 581-583
- Wetzel, S.¹ Klein, K.² Renner, S.³ Rauh, D.⁴ Oprea, T.I.⁵ Mutzel, P.⁶ Waldman, H.⁷

10
- 0024239320
- B. E. Evans, K. E. Rittle, M. G. Bock, R. M. DiPardo, R. M. Freidinger, W. L. Whitter, G. F. Lundell, D. F. Veber, P. S. Anderson, J. Med. Chem. 1988, 31, 2235-2246.
- (1988) J. Med. Chem. , vol.31 , pp. 2235-2246
- Evans, B.E.¹ Rittle, K.E.² Bock, M.G.³ Dipardo, R.M.⁴ Freidinger, R.M.⁵ Whitter, W.L.⁶ Lundell, G.F.⁷ Veber, D.F.⁸ Anderson, P.S.⁹

11
- 45249123879
- A. H. Lipkus, Q. Yuan, K. A. Lucas, S. A. Funk, W. F. Bartelt III, R. J. Schenck, A. J. Trippe, J. Org. Chem. 2008, 73, 4443-4451.
- (2008) J. Org. Chem. , vol.73 , pp. 4443-4451
- Lipkus, A.H.¹ Yuan, Q.² Lucas, K.A.³ Funk, S.A.⁴ Bartelt Iii, W.F.⁵ Schenck, R.J.⁶ Trippe, A.J.⁷

12
- 3843107553
- a) M. D. Burke, S. L. Schreiber, Angew. Chem. 2004, 116, 48-60;
- (2004) Angew. Chem. , vol.116 , pp. 48-60
- Burke, M.D.¹ Schreiber, S.L.²

13
- 33746297230
- Angew. Chem. Int. Ed. 2004, 43, 46-58;
- (2004) Angew. Chem. Int. Ed. , vol.43 , pp. 46-58

14
- 48149108752
- b) C. Cordier, D. Morton, S. Murrison, A. Nelson, C. O'Leary-Steele, Nat. Prod. Rep. 2008, 25, 719-737;
- (2008) Nat. Prod. Rep. , vol.25 , pp. 719-737
- Cordier, C.¹ Morton, D.² Murrison, S.³ Nelson, A.⁴ O'Leary-Steele, C.⁵

15
- 53549112039
- c) T. E. Nielsen, S. L. Schreiber, Angew. Chem. 2008, 120, 52-61;
- (2008) Angew. Chem. , vol.120 , pp. 52-61
- Nielsen, T.E.¹ Schreiber, S.L.²

16
- 53549092912
- Angew. Chem. Int. Ed. 2008, 47, 48-56.
- (2008) Angew. Chem. Int. Ed. , vol.47 , pp. 48-56

17
- 7444242717
- a) M. D. Burke, E. M. Berger, S. L. Schreiber, J. Am. Chem. Soc. 2004, 126, 14095-14104;
- (2004) J. Am. Chem. Soc. , vol.126 , pp. 14095-14104
- Burke, M.D.¹ Berger, E.M.² Schreiber, S.L.³

18
- 12344293904
- H. Oguri, S. L. Schreiber, Org. Lett. 2005, 7, 47-50.
- (2005) Org. Lett. , vol.7 , pp. 47-50
- Oguri, H.¹ Schreiber, S.L.²

19
- 36049015039
- a) N. Kumagai, G. Muncipinto, S. L. Schreiber, Angew. Chem. 2006, 118, 3717-3720;
- (2006) Angew. Chem. , vol.118 , pp. 3717-3720
- Kumagai, N.¹ Muncipinto, G.² Schreiber, S.L.³

20
- 33746272686
- Angew. Chem. Int. Ed. 2006, 45, 3635-3638;
- (2006) Angew. Chem. Int. Ed. , vol.45 , pp. 3635-3638

21
- 35548975293
- J. D. Sunderhaus, C. Dockendorff, S. F. Martin, Org. Lett. 2007, 9, 4223-4226;
- (2007) Org. Lett. , vol.9 , pp. 4223-4226
- Sunderhaus, J.D.¹ Dockendorff, C.² Martin, S.F.³

22
- 33746720909
- E. E. Wyatt, S. Fergus, W. R. J. D. Galloway, A. Bender, D. J. Fox, A. T. Plowright, A. S. Jessiman, M. Welch, D. R. Spring, Chem. Commun. 2006, 3296.
- (2006) Chem. Commun. , pp. 3296
- Wyatt, E.E.¹ Fergus, S.² Galloway, W.R.J.D.³ Bender, A.⁴ Fox, D.J.⁵ Plowright, A.T.⁶ Jessiman, A.S.⁷ Welch, M.⁸ Spring, D.R.⁹

23
- 33845208398
- D. A. Spiegel, F. C. Schroeder, J. R. Duvall, S. L. Schreiber, J. Am. Chem. Soc. 2006, 128, 14766-14767.
- (2006) J. Am. Chem. Soc. , vol.128 , pp. 14766-14767
- Spiegel, D.A.¹ Schroeder, F.C.² Duvall, J.R.³ Schreiber, S.L.⁴

24
- 60149087199
- D. Morton, S. Leach, C. Cordier, S. Warriner, A. Nelson, Angew. Chem. 2009, 121, 110-115;
- (2009) Angew. Chem. , vol.121 , pp. 110-115
- Morton, D.¹ Leach, S.² Cordier, C.³ Warriner, S.⁴ Nelson, A.⁵

25
- 58149346448
- Angew. Chem. Int. Ed. 2009, 48, 104-108.
- (2009) Angew. Chem. Int. Ed. , vol.48 , pp. 104-108

26
- 58149358949
- a) S. L. Schreiber, Nature 2009, 457, 153-154;
- (2009) Nature , vol.457 , pp. 153-154
- Schreiber, S.L.¹

27
- 70349966502
- W. R. J. D. Galloway, M. Diáz-Gavilán, A. Isidro-Llobet, D. R. Spring, Angew. Chem. 2009, 121, 1216-1218;
- (2009) Angew. Chem. , vol.121 , pp. 1216-1218
- Galloway, W.R.J.D.¹ Diáz-Gavilán, M.² Isidro-Llobet, A.³ Spring, D.R.⁴

28
- 60149112538
- Angew. Chem. Int. Ed. 2009, 48, 1194-1196.
- (2009) Angew. Chem. Int. Ed. , vol.48 , pp. 1194-1196

29
- 62749154638
- C. O'Leary-Steele, C. Cordier, J. Hayes, S. Warriner, A. Nelson, Org. Lett. 2009, 11, 915-918.
- (2009) Org. Lett. , vol.11 , pp. 915-918
- O'leary-Steele, C.¹ Cordier, C.² Hayes, J.³ Warriner, S.⁴ Nelson, A.⁵

30
- 0032829737
- a) D. P. Curran, Z. Luo, J. Am. Chem. Soc. 1999, 121, 9069-9072;
- (1999) J. Am. Chem. Soc. , vol.121 , pp. 9069-9072
- Curran, D.P.¹ Luo, Z.²

31
- 0348072278
- Wiley, New York
- A. Gladysz, D. P. Curran, I. T. Horvath, Handbook of Fluorous Chemistry, Wiley, New York, 2004.
- (2004) Handbook of Fluorous Chemistry
- Gladysz, A.¹ Curran, D.P.² Horvath, I.T.³

32
- 37049076286
- a) D. Craig, Chem. Soc. Rev. 1987, 16, 187-238;
- (1987) Chem. Soc. Rev. , vol.16 , pp. 187-238
- Craig, D.¹

33
- 30744456747
- K. Takao, R. Munakata, K. Tadano, Chem. Rev. 2005, 105, 4779-4807.
- (2005) Chem. Rev. , vol.105 , pp. 4779-4807
- Takao, K.¹ Munakata, R.² Tadano, K.³

34
- 0012677208
- H. Kim, C. Lee, Org. Lett. 2002, 4, 4369-4371.
- (2002) Org. Lett. , vol.4 , pp. 4369-4371
- Kim, H.¹ Lee, C.²

35
- 0029119899
- T. Fukuyama, C.-K. Jow, M. Cheung, Tetrahedron Lett. 1995, 36, 6373-6374.
- (1995) Tetrahedron Lett. , vol.36 , pp. 6373-6374
- Fukuyama, T.¹ Jow, C.-K.² Cheung, M.³

36
- 43049088465
- C. Cordier, D. Morton, S. Leach, T. Woodhall, C. O'Leary-Steele, S. Warriner, A. Nelson, Org. Biomol. Chem. 2008, 6, 1734-1737.
- (2008) Org. Biomol. Chem. , vol.6 , pp. 1734-1737
- Cordier, C.¹ Morton, D.² Leach, S.³ Woodhall, T.⁴ O'leary-Steele, C.⁵ Warriner, S.⁶ Nelson, A.⁷

37
- 0033612175
- H. D. Maynard, R. H. Grubbs, Tetrahedron Lett. 1999, 40, 4137-4140.
- (1999) Tetrahedron Lett. , vol.40 , pp. 4137-4140
- Maynard, H.D.¹ Grubbs, R.H.²

38
- 34247487884
- See: a) I. C. Stewart, T. Ung, A. A. Pletnev, J. M. Berlin, R. H. Grubbs, Y. Schrodi, Org. Lett. 2007, 9, 1589-1592;
- (2007) Org. Lett. , vol.9 , pp. 1589-1592
- Stewart, I.C.¹ Ung, T.² Pletnev, A.A.³ Berlin, J.M.⁴ Grubbs, R.H.⁵ Schrodi, Y.⁶

39
- 34147174302
- J. M. Berlin, K. Campbell, T. Ritter, T.W. Funk, A. Chlenov, R. H. Grubbs, Org. Lett. 2007, 9, 1339-1342.
- (2007) Org. Lett. , vol.9 , pp. 1339-1342
- Berlin, J.M.¹ Campbell, K.² Ritter, T.³ Funk, T.W.⁴ Chlenov, A.⁵ Grubbs, R.H.⁶

40
- 0023932623
- S. Hashimoto, S Sakata, M. Sonegawa, S. Ikegami, J. Am. Chem. Soc. 1988, 110, 3670-3672.
- (1988) J. Am. Chem. Soc. , vol.110 , pp. 3670-3672
- Hashimoto, S.¹ Sakata, S.² Sonegawa, M.³ Ikegami, S.⁴

41
- 0000779252
- For examples, see: a) S. D. Burke, S. M. S. Strickland, T. H. Powner, J. Org. Chem. 1983, 48, 454-459;
- (1983) J. Org. Chem. , vol.48 , pp. 454-459
- Burke, S.D.¹ Strickland, S.M.S.² Powner, T.H.³

42
- 0021716943
- P. R. Jenkins, K. A. Menear, P. Barraclough, M. S. Nobbs, J. Chem. Soc. Chem. Commun. 1984, 1423-1424;
- (1984) J. Chem. Soc. Chem. Commun. , pp. 1423-1424
- Jenkins, P.R.¹ Menear, K.A.² Barraclough, P.³ Nobbs, M.S.⁴

43
- 33746134769
- J. Wu, W. Dai, Tetrahedron 2006, 62, 8360-8372.
- (2006) Tetrahedron , vol.62 , pp. 8360-8372
- Wu, J.¹ Dai, W.²

44
- 2942589152
- A. Deiters, S. F. Martin, Chem. Rev. 2004, 104, 2199-2238
- (2004) Chem. Rev. , vol.104 , pp. 2199-2238
- Deiters, A.¹ Martin, S.F.²

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