Epigenetic regulation of pericentromeric heterochromatin during mammalian meiosis

Cytogenetic and Genome Research

Volumn 129, Issue 4, 2010, Pages 280-289

  Khalil, A M ^a   Driscoll, D J ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

DICER; Histone modifications; Non coding RNA; RNAi; Spermatogenesis

Indexed keywords

DICER; HISTONE; RNA POLYMERASE II;

ARTICLE; CENTROMERE; CHROMATIN MODIFICATION; DNA MODIFICATION; EPIGENETICS; GENETIC REGULATION; HETEROCHROMATIN; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; MAMMAL; MEIOSIS; NONHUMAN; PACHYTENE; PERICENTROMERE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RNA INTERFERENCE;

CELLS, CULTURED; CENTROMERE; EPIGENESIS, GENETIC; HETEROCHROMATIN; HISTONES; HUMANS; MALE; MEIOSIS; RNA POLYMERASE II;

MAMMALIA;

EID: 77955712622     PISSN: 14248581     EISSN: None     Source Type: Journal    
DOI: 10.1159/000315903     Document Type: Article

References (47)

1. Ahn SH, Kim M, Buratowski S: Phosphorylation of serine 2 within the RNA polymerase II Cterminal domain couples transcription and 3 end processing. Mol Cell 13: 67-76 (2004).
2. Andersen AA, Panning B: Epigenetic gene regulation by noncoding RNAs. Curr Opin Cell Biol 15: 281-289 (2003).
3. Arney KL, Bao S, Bannister AJ, Kouzarides T, Surani MA: Histone methylation defines epigenetic asymmetry in the mouse zygote. Int J Dev Biol 46: 317-320 (2002).
4. Barski A, Cuddapah S, Cui K, Roh TY, Schones DE, et al: High-resolution profiling of histone methylations in the human genome. Cell 129: 823-837 (2007).
5. Bellve AR, Cavicchia JC, Millette CF, O'Brien DA, Bhatnagar YM, Dym M: Spermatogenic cells of the prepuberal mouse. Isolation and morphological characterization. J Cell Biol 74: 68-85 (1977).
6. Bernstein BE, Mikkelsen TS, Xie X, Kamal M, Huebert DJ, et al: A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 125: 315-326 (2006).
7. Bernstein E, Allis CD: RNA meets chromatin. Genes Dev 19: 1635-1655 (2005).
8. Bernstein E, Kim SY, Carmell MA, Murchison EP, Alcorn H, et al: Dicer is essential for mouse development. Nat Genet 35: 215-217 (2003).
9. Clermont Y: Kinetics of spermatogenesis in mammals: Seminiferous epithelium cycle and spermatogonial renewal. Physiol Rev 52: 198-236 (1972).
10. Craig JM: Heterochromatin - many flavours, common themes. Bioessays 27: 17-28 (2005).
11. Crosio C, Fimia GM, Loury R, Kimura M, Okano Y, et al: Mitotic phosphorylation of histone H3: spatio-temporal regulation by mammalian aurora kinases. Mol Cell Biol 22: 874-885 (2002).
12. Fire A, Xu S, Montgomery MK, Kostas SA, Driver SE, Mello CC: Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans . Nature 391: 806-811 (1998).
13. Fischle W, Wang Y, Allis CD: Binary switches and modification cassettes in histone biology and beyond. Nature 425: 475-479 (2003).
14. Fukagawa T, Nogami M, Yoshikawa M, Ikeno M, Okazaki T, et al: Dicer is essential for formation of the heterochromatin structure in vertebrate cells. Nat Cell Biol 6: 784-791 (2004).
15. Hake SB, Garcia BA, Kauer M, Baker SP, Shabanowitz J, et al: Serine 31 phosphorylation of histone variant H3.3 is specific to regions bordering centromeres in metaphase chromosomes. Proc Natl Acad Sci USA 102: 6344-6349 (2005).
16. Hall IM, Noma K, Grewal SI: RNA interference machinery regulates chromosome dynamics during mitosis and meiosis in fission yeast. Proc Natl Acad Sci USA 100: 193-198 (2003).
17. Kanellopoulou C, Muljo SA, Dimitrov SD, Chen X, Colin C, et al: X chromosome inactivation in the absence of DICER. Proc Natl Acad Sci USA 106:1122-1127 (2009).
18. Kato H, Goto DB, Martienssen RA, Urano T, Furukawa K, Murakami Y: RNA polymerase II is required for RNAi-dependent heterochromatin assembly. Science 309: 467-469 (2005).
19. Khalil AM, Driscoll DJ: Histone H3 lysine 4 dimethylation is enriched on the inactive sex chromosomes in male meiosis but absent on the inactive X in female somatic cells. Cytogenet Genome Res 112: 11-15 (2006).
20. Khalil AM, Driscoll DJ: Trimethylation of histone H3 lysine 4 is an epigenetic mark at regions escaping mammalian X inactivation. Epigenetics 2: 114-118 (2007).
21. Khalil AM, Boyar FZ, Driscoll DJ: Dynamic histone modifications mark sex chromosome inactivation and reactivation during mammalian spermatogenesis. Proc Natl Acad Sci USA 101: 16583-16587 (2004).
22. Lo WS, Trievel RC, Rojas JR, Duggan L, Hsu JY, et al: Phosphorylation of serine 10 in histone H3 is functionally linked in vitro and in vivo to GCN5-mediated acetylation at lysine 14. Mol Cell 5: 917-926 (2000).
23. Maatouk DM, Loveland KL, McManus MT, Moore K, Harfe BD: Dicer1 is required for differentiation of the mouse male germline. Biol Reprod 79: 696-703 (2008).
24. Martienssen RA, Zaratiegui M, Goto DB: RNA interference and heterochromatin in the fission yeast Schizosaccharomyces pombe. Trends Genet 21: 450-456 (2005).
25. Mattick JS: Non-coding RNAs: The architects of eukaryotic complexity. EMBO Rep 2: 986-991 (2001).
26. Matzke MA, Birchler JA: RNAi-mediated pathways in the nucleus. Nat Rev Genet 6: 24-35 (2005).
27. Mikkelsen TS, Ku M, Jaffe DB, Issac B, Lieberman E, et al: Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature 448: 553-560 (2007).
28. Murchison EP, Partridge JF, Tam OH, Cheloufi S, Hannon GJ: Characterization of Dicer-deficient murine embryonic stem cells. Proc Natl Acad Sci USA 102: 12135-12140 (2005).
29. Nowak SJ, Corces VG: Phosphorylation of histone H3: a balancing act between chromosome condensation and transcriptional activation. Trends Genet 20: 214-220 (2004).
30. Ogawa Y, Sun BK, Lee JT: Intersection of the RNA interference and X-inactivation pathways. Science 320: 1336-1341 (2008).
31. Orphanides G, Reinberg D: RNA polymerase II elongation through chromatin. Nature 407: 471-475 (2000).
32. Partridge JF, Debeauchamp JL, Kosinski AM, Ulrich DL, Hadler MJ, Noffsinger VJ: Functional separation of the requirements for establishment and maintenance of centromeric heterochromatin. Mol Cell 26: 593-602 (2007).
33. Peng JC, Karpen GH: H3K9 methylation and RNA interference regulate nucleolar organization and repeated DNA stability. Nat Cell Biol 9: 25-35 (2007).
34. Reinhart BJ, Bartel DP: Small RNAs correspond to centromere heterochromatic repeats. Science 297: 1831 (2002).
35. Rice JC, Allis CD: Histone methylation versus histone acetylation: new insights into epigenetic regulation. Curr Opin Cell Biol 13: 263-273 (2001).
36. Richards EJ, Elgin SC: Epigenetic codes for heterochromatin formation and silencing: Rounding up the usual suspects. Cell 108: 489-500 (2002).
37. Rideout WM 3rd, Eggan K, Jaenisch R: Nuclear cloning and epigenetic reprogramming of the genome. Science 293: 1093-1098 (2001).
38. Schotta G, Lachner M, Sarma K, Ebert A, Sengupta R, et al: A silencing pathway to induce H3-K9 and H4-K20 trimethylation at constitutive heterochromatin. Genes Dev 18: 1251-1262 (2004).
39. Sims RJ 3rd, Belotserkovskaya R, Reinberg D: Elongation by RNA polymerase II: The short and long of it. Genes Dev 18: 2437-2468 (2004a).
40. Sims RJ 3rd, Mandal SS, Reinberg D: Recent highlights of RNA-polymerase-II-mediated transcription. Curr Opin Cell Biol 16: 263-271 (2004b).
41. Strahl BD, Allis CD: The language of covalent histone modifications. Nature 403: 41-45 (2000).
42. Sugiyama T, Cam H, Verdel A, Moazed D, Grewal SI: RNA-dependent RNA polymerase is an essential component of a self-enforcing loop coupling heterochromatin assembly to siRNA production. Proc Natl Acad Sci USA 102: 152-157 (2005).
43. Suja JA, Barbero JL: Cohesin complexes and sister chromatid cohesion in mammalian meiosis. Genome Dyn 5: 94-116 (2009).
44. Turner BM: Cellular memory and the histone code. Cell 111: 285-291 (2002).
45. Vakoc CR, Mandat SA, Olenchock BA, Blobel GA: Histone H3 lysine 9 methylation and HP1gamma are associated with transcription elongation through mammalian chromatin. Mol Cell 19: 381-391 (2005).
46. Verdel A, Jia S, Gerber S, Sugiyama T, Gygi S, et al: RNAi-mediated targeting of heterochromatin by the RITS complex. Science 303: 672-676 (2004).
47. Volpe TA, Kidner C, Hall IM, Teng G, Grewal SI, Martienssen RA: Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi. Science 297: 1833- 1837 (2002).