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Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 17, 2010, Pages 5290-5294

Structure-activity studies on acetylcholinesterase inhibition in the lycorine series of Amaryllidaceae alkaloids

(5) McNulty, James a Nair, Jerald J a Little, Jessamyn R L a Brennan, John D a Bastida, Jaume b

a MCMASTER UNIVERSITY (Canada)

b UNIVERSITY OF BARCELONA (Spain)

Author keywords

Acetylcholine esterase; Alkaloids; Alzheimer's disease; Amaryllidacea; Lycorine

Indexed keywords

1 ACETOXY 2 TERT BUTYLDIMETHYLSILY LYCORINE; 1 ACETOXYLYCORINE; 1 BENZOYL 2 ACETYLLYCORINE; 1 BENZOYLLYCORINE; 1,2 EPOXYAMBELLINE; 11 HYDROXYVITTATINE; 2 TERT BUTYLDIMETHYLSILY LYCORINE; 6ALPHA HYDROXYCRINAMIDINE; 6ALPHA HYDROXYUNDULATINE; ACETYLCHOLINESTERASE; ACETYLCRINAMINE; ACETYLSANGUININE; AMABILINE; AMARYLLIDACEAE ALKALOID; AMBELLINE; CRINAMINE; CRININE; CYTOCHROME P450 3A4; DIHYDROCRINAMINE; DIHYDROHAMAYNE; GALANTAMINE; HAEMANTHAMINE; HAEMANTHIDINE; HAMAYNE; JOESEPHININE; LYCORINE; PSEUDOLYCORIN; SANGUININE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VITTATINE;

ARTICLE; CYTOTOXICITY; DRUG IDENTIFICATION; DRUG SYNTHESIS; ENZYME INHIBITION; LIPOPHILICITY; PHARMACOPHORE; SILYLATION; STRUCTURE ACTIVITY RELATION;

ALKALOIDS; CHOLINESTERASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

AMARYLLIDACEAE;

EID: 77955658321 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/j.bmcl.2010.06.130 Document Type: Article

Times cited : (66)

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