Synthesis and biological evaluation of fully functionalized seco-pancratistatin analogues

Journal of Natural Products

Volumn 71, Issue 3, 2008, Pages 357-363

  McNulty, James ^a   Nair, Jerald J ^a   Griffin, Carly ^b   Pandey, Siyaram ^b  

^a MCMASTER UNIVERSITY   (Canada)

^b UNIVERSITY OF WINDSOR   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

1,3 BENZYLIDENE; 4'' ISOPROPYL 2'' OXAZOLIDINO N[2 (3',4' METHYLENEDIOXY)PHENYL 3 TRIMETHYLSILYLOXY 4,5 ISOPROPYLIDENEDIOXY 6 TERT BUTYLDIMETHYLSILYLOXY]HEXANOATE; [1 AZIDO 2 (3',4' METHYLENEDIOXY)PHENYL 3 (O) BENZOYL 4,5 ISOPROPYLIDENEDIOXY 6 TERT BUTYLDIMETHYLSILYLOXY]HEXANE; [1 BROMO 2 (3',4' METHYLENEDIOXY)PHENYL 3 (O) BENZOYL 4,5 ISOPROPYLIDENEDIOXY 6 TERT BUTYLDIMETHYLSILYLOXY]HEXANE; [2 (3',4' METHYLENEDIOXY)PHENYL 3 HYDROXY 4,5 ISOPROPYLIDENEDIOXY 6 TERT BUTYLDIMETHYLSILYLOXY]HEXYL BENZAMIDE; [2 (3',4' METHYLENEDIOXY)PHENYL 3,6 DIHYDROXY 4,5 ISOPROPYLIDENEDIOXY]HEXYL BENZAMIDE; [2 (3',4' METHYLENEDIOXY)PHENYL 4,5 ISOPROPYLIDENEDIOXY 6 TERT BUTYLDIMETHYLSILYLOXY]HEXAN 1,3 DIOL; [2 PHENYL 4 (1'',2'' ISOPROPYLIDENEDIOXY 3 TERT BUTYLDIMETHYLSILYLOXYPROPYL) 5 (3',4'METHYLENEDIOXY)PHENYL] 1,3 DIOXANE; AMIDE; ANTINEOPLASTIC AGENT; BENZYLIDENE DERIVATIVE; ISOPROPYL 2'' OXAZOLIDINO N (3',4' METHYLENEDIOXY)PHENYL ACETATE; OXAZOLIDINONE DERIVATIVE; POLYHYDROXYAMIDE B; SECO PANCRATISTATIN; UNCLASSIFIED DRUG;

ALDOL REACTION; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; DRUG MECHANISM; DRUG SYNTHESIS; FRAGMENTATION REACTION; HUMAN; HUMAN CELL; OXIDATION; STEREOCHEMISTRY;

AMARYLLIDACEAE ALKALOIDS; ANTINEOPLASTIC AGENTS; APOPTOSIS; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; ISOQUINOLINES; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; STEREOISOMERISM;

EID: 42249111889     PISSN: 01633864     EISSN: None     Source Type: Journal    
DOI: 10.1021/np0705460     Document Type: Article

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