Total synthesis and biological evaluation of Amaryllidaceae alkaloids: Narciclasine, ent-7-deoxypancratistatin, regioisomer of 7-deoxypancratistatin, 10b-epi-deoxypancratistatin, and truncated derivatives

Journal of Organic Chemistry

Volumn 67, Issue 25, 2002, Pages 8726-8743

  Hudlicky, Tomas ^a,b   Rinner, Uwe ^a,b   Gonzalez, David ^a,b,c   Akgun, Hulya ^a,b,d   Schilling, Stefan ^a,b   Siengalewicz, Peter ^a,b   Martinot, Theodore A ^a,b   Pettit, George R ^a,b  

^a University of Florida ^*  (United States)

^b ARIZONA STATE UNIVERSITY   (United States)

^c UNIVERSIDAD DE LA REPÚBLICA   (Uruguay)

^d HACETTEPE UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCATALYSTS; CELLS; DERIVATIVES; ENZYMES; SYNTHESIS (CHEMICAL);

ALKALOIDS;

ORGANIC COMPOUNDS;

10B EPI DEOXYPANCRATISTATIN; 7 DEOXYPANCRATISTATIN; ALKALOID; AZIRIDINE DERIVATIVE; ENT 7 DEOXYPANCRATISTATIN; NARCICLASINE; UNCLASSIFIED DRUG; 10B-EPI-DEOXYPANCRATISTATIN; 7-DEOXYPANCRATISTATIN; AMARYLLIDACEAE ALKALOID; ANTINEOPLASTIC AGENT; ISOQUINOLINE DERIVATIVE; LYCORINE; PANCRATISTATIN; PHENANTHRIDINE DERIVATIVE;

ARTICLE; CANCER CELL CULTURE; DRUG ACTIVITY; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; ANGIOSPERM; ANIMAL; CATALYSIS; CELL CULTURE; CHEMICAL STRUCTURE; CHEMISTRY; CYCLIZATION; DRUG EFFECT; DRUG SCREENING; HUMAN; LEUKEMIA P 388; MEDICINAL PLANT; MOUSE; NUCLEAR MAGNETIC RESONANCE; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ALKALOIDS; AMARYLLIDACEAE ALKALOIDS; ANGIOSPERMS; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CATALYSIS; CYCLIZATION; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; ISOQUINOLINES; LEUKEMIA P388; MICE; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PHENANTHRIDINES; PLANTS, MEDICINAL; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR CELLS, CULTURED;

EID: 0037073868     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo020129m     Document Type: Article

References (149)

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