Safety and risk assessment of the genetically modified Lactococci on rats intestinal bacterial flora

International Journal of Food Microbiology

Volumn 142, Issue 1-2, 2010, Pages 164-169

  Lee, Kai Chien ^a   Liu, Chin Feng ^a   Lin, Tzu Hsing ^a   Pan, Tzu Ming ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

Genetically modified microorganism (GMM); Intestinal microflora; Lactic acid bacteria; Safety assessment

Indexed keywords

NATTOKINASE; NISIN; SUBTILISIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL HEALTH; ANIMAL TISSUE; ARTICLE; BACTERIAL STRAIN; BACTERIAL TRANSLOCATION; BIFIDOBACTERIUM; BLOOD LEVEL; BODY WEIGHT; CECUM; CLOSTRIDIUM PERFRINGENS; COLIFORM BACTERIUM; CONTROLLED STUDY; FECES MICROFLORA; HEMATOLOGICAL PARAMETERS; INTESTINE FLORA; KIDNEY SIZE; LACTOCOCCUS LACTIS; LIVER SIZE; MALE; NONHUMAN; RAT; RISK ASSESSMENT; SAFETY; SPLEEN WEIGHT; TRANSGENIC ORGANISM;

ANIMALS; BACTERIAL TRANSLOCATION; INTESTINES; LACTOCOCCUS; MALE; RATS; RATS, WISTAR;

ANIMALIA; BACTERIA (MICROORGANISMS); BIFIDOBACTERIUM; CLOSTRIDIUM PERFRINGENS; LACTOBACILLUS; LACTOCOCCUS; LACTOCOCCUS LACTIS; RATTUS; RATTUS NORVEGICUS;

EID: 77955655388     PISSN: 01681605     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijfoodmicro.2010.06.018     Document Type: Article

References (29)

1. American Institute of Nutrition Report of American Institute ad hoc on standards of nutritional studies. Journal of Nutrition 1977, 107:1340-1348.
2. Bernbom N., Licht T.R., Brogren C.H., Jelle B., Johansen A.H., Badiola I., Vogensen F.K., Nørrung B. Effects of Lactococcus lactis on composition of intestinal microbiota: role of nisin. Applied and Environmental Microbiology 2006, 72:239-244.
3. Chu B.C., Lee H. Genetic improvement of Saccharomyces cerevisiae for xylose fermentation. Biotechnology Advances 2007, 25:425-441.
4. Chung K.S., Kim C.N., Namgoong K. Evaluation of the Petrifilm rapid coliform count plate method for coliform enumeration from surimi-based imitation crab slurry. Journal of Food Protection 2000, 63:123-125.
5. de Vrese M., Schrezenmeir J. Probiotics, prebiotics, and synbiotics. Advances in Biochemical Engineering/Biotechnology 2008, 111:1-66.
6. Draft Guidance Document for the Risk Assessment of Genetically Modified Microorganisms and Their Derived Products Intended for Food and Feed Use 2005, 12-16. EFSA.
7. Report of a joint FAO/WHO expert consultation on allergenicity of foods derived from biotechnology. Evaluation of Allergenicity of Genetically Modified Foods 2001, 22-25. FAO/WHO.
8. Giknis M.L.A., Clifford C.B. Clinical Laboratory Parameters for Crl: WI(Han) Rats 2008, Charles River Labortories, Wilmington, MA, USA.
9. Hébuterne X. Gut changes attributed to ageing: effects on intestinal microflora. Current Opinion in Clinical Nutrition & Metabolic Care 2003, 6:49-54.
10. Ishibashi N., Yamazaki S. Probiotics and safety. American Journal of Clinical Nutrition 2001, 73:465-470.
11. Juang I.L., Pan T.M., Huong H.P., Huang C.J. The effects of oligosaccharide beverage on microflora in rats. Chinese Journal of Nutrition 2000, 25:232-242.
12. Kimoto-Nira H., Suzuki C., Kobayashi M., Sasaki K., Kurisaki J., Mizumachi K. Anti-ageing effect of a lactococcal strain: analysis using senescence-accelerated mice. British Journal of Nutrition 2007, 98:1178-1186.
13. Langella P., Le Loir Y. Heterologous protein secretion in Lactococcus lactis: a novel antigen delivery system. Brazilian Journal of Medical and Biological Research 1999, 32:191-198.
14. LeBlanc J.G., Burgess C., Sesma F., Savoy de Giori G., van Sinderen D. Ingestion of milk fermented by genetically modified Lactococcus lactis improves the riboflavin status of deficient rats. Journal of Dairy Science 2005, 88:3435-3442.
15. Mierau I., Kleerebezem M. 10years of the nisin-controlled gene expression system (NICE) in Lactococcus lactis. Applied Microbiology and Biotechnology 2005, 68:705-717.
16. Miglioli P.A., Allerberger F., Calabrò G.B., Gaion R.M. Effects of daily oral administration of rifaximin and neomycin on faecal aerobic flora in rats. Pharmacol Research 2001, 44:373-375.
17. Nouaille S., Ribeiro L.A., Miyoshi A., Pontes D., Le Loir Y., Oliveira S.C., Langella P., Azevedo V. Heterologous protein production and delivery systems for Lactococcus lactis. Genetics and Molecular Research 2003, 2:102-111.
18. Rhodehamel E.J., Harmon S.M. Bacteriological Analytical Manual 1998, Food and Drug Administration, Washington, D.C., USA, Chapter 16. 8th Edition.
19. Sawires Y.S., Songer J.G. Clostridium perfringens: insight into virulence evolution and population structure. Anaerobe 2006, 12:23-43.
20. Subbian E., Yabuta Y., Shinde U.P. Folding pathway mediated by an intramolecular chaperone: intrinsically unstructured propeptide modulated stochastic activation of subtilisin. Journal of Molecular Biology 2005, 347:367-383.
21. Suzuki Y., Kondo K., Ichise H., Tsukamoto Y., Urano T., Umemura K. Dietary supplementation with fermented soybeans suppresses intimal thickening. Nutrition 2003, 19:261-264.
22. Swendseid M.E. Biochemical assessment of protein and amino acid status. Proceedings of a Council of the American Health Foundation. Nutritional Status Assessment of the Individual 1987, 205-211. Food and Nutrition Press, New York. G.E. Livingston (Ed.).
23. Trebichavsky I., Rada V., Splichalova A., Splichal I. Cross-talk of human gut with Bifidobacteria. Nutrition Reviews 2009, 67:77-82.
24. Usman B., Hosono A. Hypocholesterolemic effect of Lactobacillus gasseri SBT0270 in rats fed a cholesterol-enriched diet. Journal of Dairy Research 2001, 68:617-624.
25. Van Leeuwen P.A.M., Boermeester M.A., Houdijk A.P., Ferwerda C.C., Cuesta M.A., Meyer S., Wesdrop R.I. Clinical significance of translocation. Gut 1994, 35:28-34.
26. Vaughan E.E., de Vries M.C., Zoetendal E.G., Ben-Amor K., Akkermans A.D., de Vos W.M. The intestinal LABs. Antonie Van Leeuwenhoek 2002, 82:341-352.
27. Woodmansey E.J. Intestinal bacteria and ageing. Journal of Applied Microbiology 2007, 102:1178-1186.
28. Wu J., Zhang W., Xie B., Wu M., Tong X., Kalpoe J., Zhang D. Detection and toxin typing of Clostridium perfringens in formalin-fixed, paraffin-embedded tissue samples by PCR. Journal of Clinical Microbiology 2009, 47:807-810.
29. Yakubu M.T., Akanji M.A., Oladiji A.T. Haematological evaluation in male albino rats following chronic administration of aqueous extract of Fadogia agrestis stem. Pharmacognosy Magazine 2007, 3:34-38.