Reduction of PrPCin human cerebrospinal fluid after spinal cord injury

Prion

Volumn 4, Issue 2, 2010, Pages 80-86

  Carnini, Anna ^a   Casha, Steve ^b   Yong, V Wee ^b   Hurlbert, R John ^b   Braun, Janice E A ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

Author keywords

Crystallin domain; CSF; Hsp25; PrPC; Spinal cord injury

Indexed keywords

HEAT SHOCK COGNATE PROTEIN 70; HEAT SHOCK PROTEIN 110; HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 40; HEAT SHOCK PROTEIN 90; MINOCYCLINE; PLACEBO; PRION PROTEIN; PROTEIN 14 3 3;

ADULT; AGED; ARTICLE; CELL SURVIVAL; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; LOADING DRUG DOSE; MALE; NERVE CELL; NEUROPROTECTION; PROTEIN CEREBROSPINAL FLUID LEVEL; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN SECRETION; PROTEIN SYNTHESIS; QUALITY CONTROL; RANDOMIZED CONTROLLED TRIAL; SPINAL CORD DECOMPRESSION; SPINAL CORD INJURY;

14-3-3 PROTEINS; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BLOTTING, WESTERN; CATHETERS, INDWELLING; CEREBROSPINAL FLUID PRESSURE; CRYSTALLINS; FEMALE; HEAT-SHOCK PROTEINS; HUMANS; IMMUNOGLOBULIN G; MALE; MIDDLE AGED; MINOCYCLINE; MOLECULAR CHAPERONES; PERFUSION; PRPC PROTEINS; SPINAL CORD INJURIES; YOUNG ADULT;

EID: 77955641208     PISSN: 19336896     EISSN: 1933690X     Source Type: Journal    
DOI: 10.4161/pri.4.2.11756     Document Type: Article

References (50)

1. Watts JC, Westaway D. The prion protein family: diversity, rivalry and dysfunction. Biochim Biophys Acta 2007; 1772:654-72. (Pubitemid 46880210)
2. Gains MJ, LeBlanc AC. Canadian Association of Neurosciences Review: prion protein and prion diseases: the good and the bad. Can J Neurol Sci 2007; 34:126-45.
3. Stahl N, Borchelt DR, Hsiao K, Prusiner SB. Scrapie prion protein contains a phosphatidylinositol glycolipid. Cell 1987; 51:229-40.
4. Naslavsky N, Stein R, Yanai A, Friedlander G, Taraboulos A. Characterization of detergent-insoluble complexes containing the cellular prion protein and its scrapie isoform. J Biol Chem 1997; 272:6324-31. (Pubitemid 27118107)
5. Haraguchi T, Fisher S, Olofsson S, Endo T, Groth D, Tarentino A, et al. Asparagine-linked glycosylation of the scrapie and cellular prion proteins. Arch Biochem Biophys 1989; 274:1-13.
6. Sales N, Rodolfo K, Hassig R, Faucheux B, Di Giamberardino L, Moya KL. Cellular prion protein localization in rodent and primate brain. Eur J Neurosci 1998; 10:2464-71. (Pubitemid 28302347)
7. Ford MJ, Burton LJ, Morris RJ, Hall SM. Selective expression of prion protein in peripheral tissues of the adult mouse. Neuroscience 2002; 113:177-92.
8. Büeler H, Aguzzi A, Sailer A, Greiner RA, Autenried P, Aguet M, et al. Mice devoid of PrP are resistant to scrapie. Cell 1993; 73:1339-47. (Pubitemid 23201147)
9. Prusiner SB. Novel proteinaceous infectious particles cause scrapie. Science 1982; 216:136-44.
10. Davies GA, Bryant AR, Reynolds JD, Jirik FR, Sharkey KA. Prion diseases and the gastrointestinal tract. Can J Gastroenterol 2006; 20:18-24.
11. DebBurman SK, Raymond GJ, Caughey B, Lindquist S. Chaperone-supervised conversion of prion protein to its protease-resistant form. Proc Natl Acad Sci USA 1997; 94:13938-43. (Pubitemid 28009688)
12. Edenhofer F, Rieger R, Famulok M, Wendler W, Weiss S, Winnacker EL. Prion protein PrPc interacts with molecular chaperones of the Hsp60 family. J Virol 1996; 70:4724-8. (Pubitemid 26187466)
13. C directly interacts with alphaB-crystalline. FEBS Lett 2005; 579:5419-24.
14. Beck KE, Kay JG, Braun JE. Rdj2, a J protein family member, interacts with cellular prion PrP(C). Biochem Biophys Res Commun 2006; 346:866-71.
15. Rambold AS, Miesbauer M, Rapaport D, Bartke T, Baier M, Winklhofer KF, et al. Association of Bcl-2 with misfolded prion protein is linked to the toxic potential of cytosolic PrP. Mol Biol Cell 2006; 17:3356-68. (Pubitemid 44156431)
16. Capellari S, Zaidi SI, Urig CB, Perry G, Smith MA, Petersen RB. Prion protein glycosylation is sensitive to redox change. J Biol Chem 1999; 274:34846-50. (Pubitemid 129509530)
17. Ochel HJ, Gademann G, Trepel J, Neckers L. Modulation of prion protein structural integrity by geldanamycin. Glycobiology 2003; 13:655-60. (Pubitemid 37220444)
18. Calderwood SK, Mambula SS, Gray PJ Jr, Theriault JR. Extracellular heat shock proteins in cell signaling. FEBS Lett 2007; 581:3689-94.
19. Tytell M, Robinson MC, Milligan CE. Release of Heat Shock Proteins and their Effects When in the Extracellular Space in the Nervous System. Springer 2008.
20. Wilson MR, Yerbury JJ, Poon S. Extracellular Chaperones and Amyloids. Asea AA, Brown IR, editors. Springer. Heat Shock Proteins and the Brain: Implications for Neurodegenerative Diseases and Neuroprotection. Asea AA and Calderwood SK. Ref Type: Serial (Book, Monograph) 2008; 3:283-315.
21. Steele AD, Hutter G, Jackson WS, Heppner FL, Borkowski AW, King OD, et al. Heat shock factor 1 regulates lifespan as distinct from disease onset in prion disease. Proc Natl Acad Sci USA 2008.
22. Picard-Hagen N, Gayrard V, Viguie C, Moudjou M, Imbs C, Toutain PL. Prion protein in the cerebrospinal fluid of healthy and naturally scrapie-affected sheep. J Gen Virol 2006; 87:3723-7. (Pubitemid 44817007)
23. Vella LJ, Greenwood DL, Cappai R, Scheerlinck JP, Hill AF. Enrichment of prion protein in exosomes derived from ovine cerebral spinal fluid. Vet Immunol Immunopathol 2008; 124:385-93.
24. Castagna A, Campostrini N, Farinazzo A, Zanusso G, Monaco S, Righetti PG. Comparative two-dimensional mapping of prion protein isoforms in human cerebrospinal fluid and central nervous system. Electrophoresis 2002; 23:339-46. (Pubitemid 34157102)
25. Stahl N, Borchelt DR, Prusiner SB. Differential release of cellular and scrapie prion proteins from cellular membranes by phosphatidylinositol-specific phospholipase C. Biochemistry 1990; 29:5405-12. (Pubitemid 20193950)
26. Fevrier B, Vilette D, Archer F, Loew D, Faigle W, Vidal M, et al. Cells release prions in association with exosomes. Proc Natl Acad Sci USA 2004; 101:9683-8. (Pubitemid 38869296)
27. Kuwahara C, Takeuchi AM, Nishimura T, Haraguchi K, Kubosaki A, Matsumoto Y, et al. Prions prevent neuronal cell-line death. Nature 1999; 400:225-6. (Pubitemid 29334128)
28. McLennan NF, Brennan PM, McNeill A, Davies I, Fotheringham A, Rennison KA, et al. Prion protein accumulation and neuroprotection in hypoxic brain damage. Am J Pathol 2004; 165:227-35. (Pubitemid 38821830)
29. Spudich A, Frigg R, Kilic E, Kilic U, Oesch B, Raeber A, et al. Aggravation of ischemic brain injury by prion protein deficiency: role of ERK-1/-2 and STAT-1. Neurobiol Dis 2005; 20:442-9. (Pubitemid 41476270)
30. Weise J, Doeppner TR, Müller T, Wrede A, Schulz-Schaeffer W, Zerr I, et al. Overexpression of cellular prion protein alters postischemic Erk1/2 phosphorylation but not Akt phosphorylation and protects against focal cerebral ischemia. Restor Neurol Neurosci 2008; 26:57-64. (Pubitemid 351630029)
31. C by adenovirus-mediated gene targeting reduces ischemic injury in a stroke rat model. J Neurosci 2005; 25:8967-77.
32. Mitteregger G, Vosko M, Krebs B, Xiang W, Kohlmannsperger V, Nölting S, et al. The role of the octarepeat region in neuroprotective function of the cellular prion protein. Brain Pathol 2007; 17:174-83. (Pubitemid 46466137)
33. C) protects neuronal cells from the effect of huntingtin aggregation. J Cell Sci 2007; 120:2663-71.
34. c) after focal cerebral ischemia and influence of lesion severity. Neurosci Lett 2004; 372:146-50.
35. Bounhar Y, Zhang Y, Goodyer CG, LeBlanc A. Prion protein protects human neurons against Bax-mediated apoptosis. J Biol Chem 2001; 276:39145-9. (Pubitemid 37371285)
36. Walz R, Amaral OB, Rockenbach IC, Roesler R, Izquierdo I, Cavalheiro EA, et al. Increased sensitivity to seizures in mice lacking cellular prion protein. Epilepsia 1999; 40:1679-82.
37. Shmerling D, Hegyi I, Fischer M, Blättler T, Brandner S, Götz J, et al. Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions. Cell 1998; 93:203-14. (Pubitemid 28180854)
38. Nishida N, Tremblay P, Sugimoto T, Shigematsu K, Shirabe S, Petromilli C, et al. A mouse prion protein transgene rescues mice deficient for the prion protein gene from purkinje cell degeneration and demyelination. Lab Invest 1999; 79:689-97. (Pubitemid 29283422)
39. Brown P, Gibbs CJ Jr, Rodgers-Johnson P, Asher DM, Sulima MP, Bacote A, et al. Human spongiform encephalopathy: the National Institutes of Health series of 300 cases of experimentally transmitted disease. Ann Neurol 1994; 35:513-29. (Pubitemid 24153834)
40. Forloni G, Iussich S, Awan T, Colombo L, Angeretti N, Girola L, et al. Tetracyclines affect prion infectivity. Proc Natl Acad Sci USA 2002; 99:10849-54.
41. Wong BS, Green AJ, Li R, Xie Z, Pan T, Liu T, et al. Absence of protease-resistant prion protein in the cerebrospinal fluid of Creutzfeldt-Jakob disease. J Pathol 2001; 194:9-14. (Pubitemid 32390442)
42. Tagliavini F, Prelli F, Porro M, Salmona M, Bugiani O, Frangione B. A soluble form of prion protein in human cerebrospinal fluid: implications for prion-related encephalopathies. Biochem Biophys Res Commun 1992; 184:1398-404.
43. Yutzy B, Holznagel E, Coulibaly C, Stuke A, Hahmann U, Deslys JP, et al. Time-course studies of 14-3-3 protein isoforms in cerebrospinal fluid and brain of primates after oral or intracerebral infection with bovine spongiform encephalopathy agent. J Gen Virol 2007; 88:3469-78. (Pubitemid 350201859)
44. Armstrong CL, Krueger-Naug AM, Currie RW, Hawkes R. Constitutive expression of the 25-kDa heat shock protein Hsp25 reveals novel parasagittal bands of purkinje cells in the adult mouse cerebellar cortex. J Comp Neurol 2000; 416:383-97. (Pubitemid 30027135)
45. Armstrong CL, Krueger-Naug AM, Currie RW, Hawkes R. Constitutive expression of heat shock protein HSP25 in the central nervous system of the developing and adult mouse. J Comp Neurol 2001; 434:262-74. (Pubitemid 32402134)
46. Khosravani H, Zhang Y, Tsutsui S, Hameed S, Altier C, Hamid J, et al. Prion protein attenuates excitotoxicity by inhibiting NMDA receptors. J Cell Biol 2008; 181:551-65.
47. Meyne F, Gloeckner SF, Ciesielczyk B, Heinemann U, Krasnianski A, Meissner B, et al. Total prion protein levels in the cerebrospinal fluid are reduced in patients with various neurological disorders. J Alzheimers Dis 2009; 17:863-73.
48. Ford MJ, Burton LJ, Li H, Graham CH, Frobert Y, Grassi J, et al. A marked disparity between the expression of prion protein and its message by neurones of the CNS. Neuroscience 2002; 111:533-51. (Pubitemid 34521894)
49. Rosales-Hernandez A, Beck KE, Zhao X, Braun AP, Braun JE. RDJ2 (DNAJA2) chaperones neural G protein signaling pathways. Cell Stress Chaperones 2008; 14:71-82.
50. Gibbs SJ, Barren B, Beck KE, Proft J, Zhao X, Noskova T, et al. Hsp40 couples with the CSPalpha chaperone complex upon induction of the heat shock response. PLoS ONE 2009; 4:4595.