Modulation of prion protein structural integrity by geldanamycin

Glycobiology

Volumn 13, Issue 9, 2003, Pages 655-660

  Ochel, Hans Joachim ^a   Gademann, G ^a   Trepel, J ^b   Neckers, L ^b  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Conformation; Geldanamycin; Glycosylation; Hsp90; Prion

Indexed keywords

ANSAMYCIN DERIVATIVE; ANTIBIOTIC AGENT; BENZOQUINONE; CELL PROTEIN; CHAPERONE; GELDAMPICIN; GELDANAMYCIN; GLYCOPEPTIDASE; HEAT SHOCK PROTEIN 90; MESSENGER RNA; PRION PROTEIN; PROTEIN INHIBITOR; RADICICOL; TUNICAMYCIN; UNCLASSIFIED DRUG;

ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DEGENERATIVE DISEASE; DEGLYCOSYLATION; EUKARYOTIC CELL; HUMAN; HUMAN CELL; PRION DISEASE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FAMILY; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; RNA SYNTHESIS; WESTERN BLOTTING;

BENZOQUINONES; CELL LINE, TUMOR; HSP90 HEAT-SHOCK PROTEINS; HUMANS; LACTAMS, MACROCYCLIC; LACTONES; MACROLIDES; MOLECULAR STRUCTURE; PEPTIDE-N4-(N-ACETYL-BETA-GLUCOSAMINYL) ASPARAGINE AMIDASE; PRION DISEASES; PRIONS; PROTEIN CONFORMATION; QUINONES; TUNICAMYCIN;

EUKARYOTA;

EID: 0141841590     PISSN: 09596658     EISSN: None     Source Type: Journal    
DOI: 10.1093/glycob/cwg081     Document Type: Article

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