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Volumn 5, Issue 7, 2010, Pages

Distinct pools of cdc25C are phosphorylated on specific TP sites and differentially localized in human mitotic cells

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN B1; ISOPROTEIN; POLO LIKE KINASE 1; PROTEIN TYROSINE PHOSPHATASE; THREONINE;

EID: 77955614031     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0011798     Document Type: Article
Times cited : (13)

References (47)
  • 1
    • 0028931265 scopus 로고
    • Principles of cdk regulation
    • Morgan DO (1995) Principles of cdk regulation. Nature 374: 131-134.
    • (1995) Nature , vol.374 , pp. 131-134
    • Morgan, D.O.1
  • 3
    • 0842324788 scopus 로고    scopus 로고
    • Recycling the cell cycle: Cyclins revisited
    • Murray AW (2004) Recycling the cell cycle: cyclins revisited. Cell 116: 221-34.
    • (2004) Cell , vol.116 , pp. 221-234
    • Murray, A.W.1
  • 4
    • 0027296041 scopus 로고
    • The MO15 gene encodes the catalytic subunit of a protein kinase that activates cdc2 and other cyclin-dependent kinases (CDKs) through phosphorylation of Thr161 and its homologues
    • Fesquet D, Labbe JC, Derancourt J, Capony JP, Galas S, et al. (1993) The MO15 gene encodes the catalytic subunit of a protein kinase that activates cdc2 and other cyclin-dependent kinases (CDKs) through phosphorylation of Thr161 and its homologues. EMBO J 12: 3111-21.
    • (1993) EMBO J , vol.12 , pp. 3111-3121
    • Fesquet, D.1    Labbe, J.C.2    Derancourt, J.3    Capony, J.P.4    Galas, S.5
  • 5
    • 0642286495 scopus 로고    scopus 로고
    • Cyclin B1 and CDK1: Nuclear localization and upstream regulators
    • Porter LA, Donoghue DJ (2003) Cyclin B1 and CDK1: nuclear localization and upstream regulators. Prog Cell Cycle Res 5: 335-47.
    • (2003) Prog Cell Cycle Res , vol.5 , pp. 335-347
    • Porter, L.A.1    Donoghue, D.J.2
  • 6
    • 0036302167 scopus 로고    scopus 로고
    • Initial activation of cyclin-B1-cdc2 kinase requires phosphorylation of cyclin B1
    • Peter M, Le Peuch C, Labbe JC, Meyer AN, Donoghue DJ, et al. (2002) Initial activation of cyclin-B1-cdc2 kinase requires phosphorylation of cyclin B1. EMBO Rep 3: 551-6.
    • (2002) EMBO Rep , vol.3 , pp. 551-556
    • Peter, M.1    Le, P.C.2    Labbe, J.C.3    Meyer, A.N.4    Donoghue, D.J.5
  • 7
    • 0033629383 scopus 로고    scopus 로고
    • Cell cycle regulation by the Cdc25 phosphatase family
    • Nilsson I, Hoffmann I (2000) Cell cycle regulation by the Cdc25 phosphatase family. Prog Cell Cycle Res 4: 107-14.
    • (2000) Prog Cell Cycle Res , vol.4 , pp. 107-114
    • Nilsson, I.1    Hoffmann, I.2
  • 8
    • 0036847320 scopus 로고    scopus 로고
    • Regulation of G(2)/M events by Cdc25A through phosphorylation-dependent modulation of its stability
    • Mailand N, Podtelejnikov AV, Groth A, Mann M, Bartek J, et al. (2002) Regulation of G(2)/M events by Cdc25A through phosphorylation-dependent modulation of its stability. EMBO J 21: 5911-20.
    • (2002) EMBO J , vol.21 , pp. 5911-5920
    • Mailand, N.1    Podtelejnikov, A.V.2    Groth, A.3    Mann, M.4    Bartek, J.5
  • 9
    • 0031669731 scopus 로고    scopus 로고
    • The cdc25B phosphatase is essential for the G2/M phase transition in human cells
    • Lammer C, Wagerer S, Saffrich R, Mertens D, Ansorge W, et al. (1998) The cdc25B phosphatase is essential for the G2/M phase transition in human cells. J Cell Sci 111: 2445-2453.
    • (1998) J Cell Sci , vol.111 , pp. 2445-2453
    • Lammer, C.1    Wagerer, S.2    Saffrich, R.3    Mertens, D.4    Ansorge, W.5
  • 10
    • 0025324692 scopus 로고
    • Human homolog of fission yeast cdc25 mitotic inducer is predominantly expressed in G2
    • Sadhu K, Reed SI, Richardson H, Russel P (1990) Human homolog of fission yeast cdc25 mitotic inducer is predominantly expressed in G2. Proc Natl Acad Sci U S A 87: 5139-5143.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 5139-5143
    • Sadhu, K.1    Reed, S.I.2    Richardson, H.3    Russel, P.4
  • 11
    • 0025917804 scopus 로고
    • P55cdc25 is a nuclear protein required for the initiation of mitosis in human cells
    • Millar JBA, Blevitt J, Gerace L, Sadhu K, Featherstone, et al. (1991) p55cdc25 is a nuclear protein required for the initiation of mitosis in human cells. Proc Natl Acad Sci U S A 88: 10500-10504.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 10500-10504
    • Millar, J.B.A.1    Blevitt, J.2    Gerace, L.3    Sadhu, K.4
  • 12
    • 0025922083 scopus 로고
    • Dephosphorylation and activation of a p34cdc2/cyclin B complex in vitro by human CDC25 protein
    • Strausfeld U, Labbé J.-C, Fesquet D, Cavadore J-C, Picard A, et al. (1991) Dephosphorylation and activation of a p34cdc2/cyclin B complex in vitro by human CDC25 protein. Nature 351: 242-245.
    • (1991) Nature , vol.351 , pp. 242-245
    • Strausfeld, U.1    Labbé, J.-C.2    Fesquet, D.3    Cavadore, J.-C.4    Picard, A.5
  • 13
    • 0026709066 scopus 로고
    • Cdc25 is a nuclear protein expressed constitutively throughout the cell cycle in non-transformed mammalian cells
    • Girard F, Strausfeld U, Cavadore J-C, Russel P, Fernandez A, et al. (1992) cdc25 is a nuclear protein expressed constitutively throughout the cell cycle in non-transformed mammalian cells. J Cell Biol 118: 785-794.
    • (1992) J Cell Biol , vol.118 , pp. 785-794
    • Girard, F.1    Strausfeld, U.2    Cavadore, J.-C.3    Russel, P.4    Fernandez, A.5
  • 14
    • 0027746003 scopus 로고
    • Elimination of cdc2 phosphorylation sites in the cdc25 phosphatase blocks initiation of M-phase
    • Izumi T, Maller JL (1993) Elimination of cdc2 phosphorylation sites in the cdc25 phosphatase blocks initiation of M-phase. Mol Biol Cell 4: 1337-1350.
    • (1993) Mol Biol Cell , vol.4 , pp. 1337-1350
    • Izumi, T.1    Maller, J.L.2
  • 15
    • 0029039470 scopus 로고
    • Phosphorylation and activation of the Xenopus cdc25 phosphatase in the absence of cdc2 and cdk2 kinase activity
    • Izumi T, Maller JL (1995) Phosphorylation and activation of the Xenopus cdc25 phosphatase in the absence of cdc2 and cdk2 kinase activity. Mol Biol Cell 6: 215-226.
    • (1995) Mol Biol Cell , vol.6 , pp. 215-226
    • Izumi, T.1    Maller, J.L.2
  • 16
    • 0027509501 scopus 로고
    • Phosphorylation and activation of human cdc25-C by cdc2-cyclin B and its involvement in the self-amplification of MPF at mitosis
    • Hoffmann I, Clarke PR, Marcote MJ, Karsenti E, Draetta G (1993) Phosphorylation and activation of human cdc25-C by cdc2-cyclin B and its involvement in the self-amplification of MPF at mitosis. EMBO J 12: 53-63.
    • (1993) EMBO J , vol.12 , pp. 53-63
    • Hoffmann, I.1    Clarke, P.R.2    Marcote, M.J.3    Karsenti, E.4    Draetta, G.5
  • 17
    • 0028168379 scopus 로고
    • Activation of p34cdc2 protein kinase by microinjection of human cdc25C in mammalian cells
    • Strausfeld U, Fernandez A, Capony JP, Girard F, Lautredou N, et al. (1994) Activation of p34cdc2 protein kinase by microinjection of human cdc25C in mammalian cells. J Biol Chem 269: 5989-6000.
    • (1994) J Biol Chem , vol.269 , pp. 5989-6000
    • Strausfeld, U.1    Fernandez, A.2    Capony, J.P.3    Girard, F.4    Lautredou, N.5
  • 18
    • 0033695002 scopus 로고    scopus 로고
    • Control of mitosis by changes in the subcellular location of cyclin-B1-Cdk1 and Cdc25C
    • Takizawa CG, Morgan DO (2000) Control of mitosis by changes in the subcellular location of cyclin-B1-Cdk1 and Cdc25C. Curr Opin Cell Biol 12: 658-665.
    • (2000) Curr Opin Cell Biol , vol.12 , pp. 658-665
    • Takizawa, C.G.1    Morgan, D.O.2
  • 19
    • 0034543444 scopus 로고    scopus 로고
    • An additional transcript of the cdc25C gene from A431 cells encodes a functional protein
    • Bureik M, Rief N, Drescher R, Jungbluth A, Montenarh M, et al. (2000) An additional transcript of the cdc25C gene from A431 cells encodes a functional protein. Int J Oncol 17: 1251-8.
    • (2000) Int J Oncol , vol.17 , pp. 1251-1258
    • Bureik, M.1    Rief, N.2    Drescher, R.3    Jungbluth, A.4    Montenarh, M.5
  • 20
    • 0033646929 scopus 로고    scopus 로고
    • Alternative splicing in the regulatory region of the human phosphatases cdc25A and cdcd25C
    • Wegener S, Hampe W, Herrmann D, Schaller HC (2000) Alternative splicing in the regulatory region of the human phosphatases cdc25A and cdcd25C. Eur J Cell Biol 79: 810-5.
    • (2000) Eur J Cell Biol , vol.79 , pp. 810-815
    • Wegener, S.1    Hampe, W.2    Herrmann, D.3    Schaller, H.C.4
  • 21
    • 0036256260 scopus 로고    scopus 로고
    • Plk1 promotes nuclear translocation of human Cdc25C during prophase
    • Toyoshima-Morimoto F, Taniguchi E, Nishida E (2002) Plk1 promotes nuclear translocation of human Cdc25C during prophase. EMBO Rep 3: 341-8.
    • (2002) EMBO Rep , vol.3 , pp. 341-348
    • Toyoshima-Morimoto, F.1    Taniguchi, E.2    Nishida, E.3
  • 22
    • 47749085495 scopus 로고    scopus 로고
    • Characterization of centrosomal localization and dynamics of Cdc25C phosphatase in mitosis
    • Bonnet J, Coopman P, Morris MC (2008) Characterization of centrosomal localization and dynamics of Cdc25C phosphatase in mitosis. Cell Cycle 7: 1991-8.
    • (2008) Cell Cycle , vol.7 , pp. 1991-1998
    • Bonnet, J.1    Coopman, P.2    Morris, M.C.3
  • 23
    • 0030611095 scopus 로고    scopus 로고
    • Mitotic and G2 checkpoint control: Regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216
    • Peng CY, Graves PR, Thoma RS, Wu Z, Shaw AS, et al. (1997) Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216. Science 277: 1501-1505.
    • (1997) Science , vol.277 , pp. 1501-1505
    • Peng, C.Y.1    Graves, P.R.2    Thoma, R.S.3    Wu, Z.4    Shaw, A.S.5
  • 24
    • 2342536422 scopus 로고    scopus 로고
    • Cdc25C phosphorylation on serine 191 by Plk3 promotes its nuclear translocation
    • Bahassi el M, Hennigan RF, Myer DL, Stambrook PJ (2004) cdc25C phosphorylation on serine 191 by Plk3 promotes its nuclear translocation. Oncogene 23: 2658-63.
    • (2004) Oncogene , vol.23 , pp. 2658-2663
    • el Bahassi, M.1    Hennigan, R.F.2    Myer, D.L.3    Stambrook, P.J.4
  • 26
    • 0242515843 scopus 로고    scopus 로고
    • Proteomic screen finds pSer/pThrbinding domain localizing Plk1 to mitotic substrates
    • Elia AE, Cantley LC, Yaffe MB (2003) Proteomic screen finds pSer/pThrbinding domain localizing Plk1 to mitotic substrates. Science 299: 1228-31.
    • (2003) Science , vol.299 , pp. 1228-1231
    • Elia, A.E.1    Cantley, L.C.2    Yaffe, M.B.3
  • 28
    • 33751212191 scopus 로고    scopus 로고
    • Role for the PP2A/B56delta phosphatase in regulating 14-3-3 release from Cdc25 to control mitosis
    • Margolis SS, Perry JA, Forester CM, Nutt LK, Guo Y, et al. (2006) Role for the PP2A/B56delta phosphatase in regulating 14-3-3 release from Cdc25 to control mitosis. Cell 127: 759-73.
    • (2006) Cell , vol.127 , pp. 759-773
    • Margolis, S.S.1    Perry, J.A.2    Forester, C.M.3    Nutt, L.K.4    Guo, Y.5
  • 30
    • 33947322004 scopus 로고    scopus 로고
    • Regulation of cdc25C by ERK-MAP kinases during the G2/M transition
    • Wang R, He G, Nelman-Gonzalez M, Ashorn CL, Gallick GE, et al. (2007) Regulation of cdc25C by ERK-MAP kinases during the G2/M transition. Cell 128: 1119-32.
    • (2007) Cell , vol.128 , pp. 1119-1132
    • Wang, R.1    He, G.2    Nelman-Gonzalez, M.3    Ashorn, C.L.4    Gallick, G.E.5
  • 31
    • 0034048515 scopus 로고    scopus 로고
    • The human polo-like kinase, PLK, regulates cdc2/cyclin B through phosphorylation and activation of the cdc25C phosphatase
    • Roshak AK, Capper EA, Imburgia C, Fornwald J, Scott G, et al. (2000) The human polo-like kinase, PLK, regulates cdc2/cyclin B through phosphorylation and activation of the cdc25C phosphatase. Cell Signal 12: 405-11.
    • (2000) Cell Signal , vol.12 , pp. 405-411
    • Roshak, A.K.1    Capper, E.A.2    Imburgia, C.3    Fornwald, J.4    Scott, G.5
  • 32
    • 0033583175 scopus 로고    scopus 로고
    • Calcium/ calmodulin-dependent phosphorylation and activation of human Cdc25-C at the G2/M phase transition in HeLa cells
    • Patel R, Holt M, Philipova R, Moss S, Schulman H, et al. (1999) Calcium/ calmodulin-dependent phosphorylation and activation of human Cdc25-C at the G2/M phase transition in HeLa cells. J Biol Chem 274: 7958-68.
    • (1999) J Biol Chem , vol.274 , pp. 7958-7968
    • Patel, R.1    Holt, M.2    Philipova, R.3    Moss, S.4    Schulman, H.5
  • 33
    • 0033638180 scopus 로고    scopus 로고
    • Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins
    • Zhou XZ, Kops O, Werner A, Lu PJ, Shen M, et al. (2000) Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins. Mol Cell 6: 873-83.
    • (2000) Mol Cell , vol.6 , pp. 873-883
    • Zhou, X.Z.1    Kops, O.2    Werner, A.3    Lu, P.J.4    Shen, M.5
  • 35
    • 2942666592 scopus 로고    scopus 로고
    • Many fingers on the mitotic trigger: Posttranslational regulation of the Cdc25C phosphatase
    • Hutchins JR, Clarke PR (2004) Many fingers on the mitotic trigger: posttranslational regulation of the Cdc25C phosphatase. Cell Cycle 3: 41-5.
    • (2004) Cell Cycle , vol.3 , pp. 41-45
    • Hutchins, J.R.1    Clarke, P.R.2
  • 36
    • 0038446759 scopus 로고    scopus 로고
    • Functional cdc25C dual-specificity phosphatase is required for S-phase entry in human cells
    • Turowski P, Franckhauser C, Morris MC, Vaglio P, Fernandez A, et al. (2003) Functional cdc25C dual-specificity phosphatase is required for S-phase entry in human cells. Mol Biol Cell 14: 2984-98.
    • (2003) Mol Biol Cell , vol.14 , pp. 2984-2998
    • Turowski, P.1    Franckhauser, C.2    Morris, M.C.3    Vaglio, P.4    Fernandez, A.5
  • 37
    • 26444493574 scopus 로고    scopus 로고
    • Cdc25B cooperates with Cdc25A to induce mitosis but has a unique role in activating cyclin B1-Cdk1 at the centrosome
    • Lindqvist A, Källström H, Lundgren A, Barsoum E, Rosenthal CK (2005) Cdc25B cooperates with Cdc25A to induce mitosis but has a unique role in activating cyclin B1-Cdk1 at the centrosome. J Cell Biol 171: 35-45.
    • (2005) J Cell Biol , vol.171 , pp. 35-45
    • Lindqvist, A.1    Källström, H.2    Lundgren, A.3    Barsoum, E.4    Rosenthal, C.K.5
  • 39
    • 0029079267 scopus 로고
    • Cell cycle regulation of the activity and subcellular localization of PLK1, a human protein kinase implicated in mitotic spindle function
    • Golsteyn RM, Mundt KE, Fry AM, Nigg EA (1995) Cell cycle regulation of the activity and subcellular localization of PLK1, a human protein kinase implicated in mitotic spindle function. J Cell Biol 129: 1617-1628.
    • (1995) J Cell Biol , vol.129 , pp. 1617-1628
    • Golsteyn, R.M.1    Mundt, K.E.2    Fry, A.M.3    Nigg, E.A.4
  • 40
    • 33646468623 scopus 로고    scopus 로고
    • Phosphorylation of the Pro-X-Thr-Pro site in phosphatase inhibitor-2 by cyclin-dependent protein kinase during M-phase of the cell cycle
    • Li M, Stefansson B, Wang W, Schaefer EM, Brautigan DL (2006) Phosphorylation of the Pro-X-Thr-Pro site in phosphatase inhibitor-2 by cyclin-dependent protein kinase during M-phase of the cell cycle. Cell Signal 18: 1318-26.
    • (2006) Cell Signal , vol.18 , pp. 1318-1326
    • Li, M.1    Stefansson, B.2    Wang, W.3    Schaefer, E.M.4    Brautigan, D.L.5
  • 41
    • 37549041244 scopus 로고    scopus 로고
    • Cdc25B involvement in the centrosome duplication cycle and in microtubule nucleation
    • Boutros R, Lobjois V, Ducommun B (2007) cdc25B involvement in the centrosome duplication cycle and in microtubule nucleation. Cancer Res 67: 11557-64.
    • (2007) Cancer Res , vol.67 , pp. 11557-11564
    • Boutros, R.1    Lobjois, V.2    Ducommun, B.3
  • 43
    • 57749084853 scopus 로고    scopus 로고
    • Overexpression of the dual specificity phosphatase, Cdc25C, confers sensitivity on tumor cells to doxorubicin-induced cell death
    • Varmeh S, Manfredi JJ (2008) Overexpression of the dual specificity phosphatase, Cdc25C, confers sensitivity on tumor cells to doxorubicin-induced cell death. Mol Cancer Ther 7: 3789-99.
    • (2008) Mol Cancer Ther , vol.7 , pp. 3789-3799
    • Varmeh, S.1    Manfredi, J.J.2
  • 44
    • 33644767315 scopus 로고    scopus 로고
    • Normal cells, but not cancer cells, survive severe Plk1 depletion
    • Liu X, Lei M, Erikson RL (2006) Normal cells, but not cancer cells, survive severe Plk1 depletion. Mol Cell Biol 26: 2093-2108.
    • (2006) Mol Cell Biol , vol.26 , pp. 2093-2108
    • Liu, X.1    Lei, M.2    Erikson, R.L.3
  • 45
    • 0037172998 scopus 로고    scopus 로고
    • Activation of Cdc2/cyclin B and inhibition of centrosome amplification in cells depleted of Plk1 by siRNA
    • Liu X, Erikson RL (2002) Activation of Cdc2/cyclin B and inhibition of centrosome amplification in cells depleted of Plk1 by siRNA. Proc Natl Acad Sci U S A 99: 8672-6.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 8672-8676
    • Liu, X.1    Erikson, R.L.2
  • 46
    • 0026320075 scopus 로고
    • Cyclin A is required for the onset of DNA replication in mammalian fibroblasts
    • Girard F, Strausfeld U, Fernandez A, Lamb NJ (1991) Cyclin A is required for the onset of DNA replication in mammalian fibroblasts. Cell 67: 1169-1179.
    • (1991) Cell , vol.67 , pp. 1169-1179
    • Girard, F.1    Strausfeld, U.2    Fernandez, A.3    Lamb, N.J.4
  • 47
    • 0030842531 scopus 로고    scopus 로고
    • Microinjection of antibodies into mammalian cells
    • Lamb NJC, Fernandez A (1997) Microinjection of antibodies into mammalian cells. Methods Enzymol 283: 72-83.
    • (1997) Methods Enzymol , vol.283 , pp. 72-83
    • Lamb, N.J.C.1    Fernandez, A.2


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