Initial activation of cyclin-B1-cdc2 kinase requires phosphorylation of cyclin B1

EMBO Reports

Volumn 3, Issue 6, 2002, Pages 551-556

  Peter, Marion ^a   Le Peuch, Christian ^a   Labbé, Jean Claude ^a   Meyer, April N ^a   Donoghue, Daniel J ^a   Dorée, Marcel ^a  

^a CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN B1; PROTEIN KINASE; PROTEIN TYROSINE PHOSPHATASE; CDC25C PROTEIN; CELL CYCLE PROTEIN; CYCLIN B; CYCLIN DEPENDENT KINASE 1; MATURATION PROMOTING FACTOR; PLX1 PROTEIN, XENOPUS; PROTEIN SERINE THREONINE KINASE; XENOPUS PROTEIN;

ANIMAL CELL; ARTICLE; CELL CYCLE G2 PHASE; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVATION; FEMALE; IN VIVO STUDY; NONHUMAN; PHASE TRANSITION; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; ANIMAL; METABOLISM; OOCYTE; PHOSPHORYLATION; XENOPUS;

ANIMALS; CDC2 PROTEIN KINASE; CDC25 PHOSPHATASE; CELL CYCLE PROTEINS; CYCLIN B; ENZYME ACTIVATION; MATURATION-PROMOTING FACTOR; OOCYTES; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; XENOPUS; XENOPUS PROTEINS;

EID: 0036302167     PISSN: 1469221X     EISSN: None     Source Type: Journal    
DOI: 10.1093/embo-reports/kvf111     Document Type: Article

References (41)

1. 2/M-phase transition of the cell cycle in Xenopus eggs
2. Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo
3. Intra-M phase-promoting factor phosphorylation of cyclin B at the prophase/metaphase transition
4. Cyclin B2-null mice develop normally and are fertile whereas cyclin B1-null mice die in utero
5. Role of nuclear material in the early cell cycle of Xenopus embryos
6. From Cdc2 to Cdk1: When did the cell cycle kinase join its partner
7. Germinal vesicle material is dispensable for oscillations in cdc2 and MAP kinase activities, cyclin B degradation and synthesis during meiosis in Xenopus oocytes
8. Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: Evidence for multiple roles of mitotic cyclins
9. Cyclin B in Xenopus oocytes: Implications for the mechanism of pre-MPF activation
10. cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2
11. MPF localization is controlled by nuclear export
12. Translocation of cyclin B1 to the nucleus at prophase requires a phosphorylation-dependent nuclear import signal
13. New B-type cyclin synthesis is required between meiosis I and II during Xenopus oocyte maturation
14. Phosphorylation and activation of human cdc25-C by cdc2-cyclin B and its involvement in the self-amplification of MPF at mitosis
15. Phosphorylation of Xenopus cyclins B1 and B2 is not required for cell cycle transitions
16. Oscillation of MPF is accompanied by periodic association between cdc25 and cdc2-cyclin B
17. Mitosis in transition
18. On the synthesis and destruction of A- and B-type cyclins during oogenesis and meiotic maturation in Xenopus laevis
19. Purification and molecular cloning of Plx1, a Cdc25-regulatory kinase from Xenopus egg extracts
20. MPF from starfish oocytes at first meiotic metaphase is an heterodimer comprising one molecule of cdc2 and one molecule of cyclin B
21. M phase-specific cdc2 kinase: Preparation from starfish oocytes and properties
22. 2/M transition in Xenopus extracts
23. Requirement for phosphorylation of cyclin B1 for Xenopus oocyte maturation
24. Nuclear localization of cyclin B1 mediates its biological activity and is regulated by phosphorylation
25. Cytoplasmic control of nuclear behavior during meiotic maturation of frog oocytes
26. Cyclin is a component of the sea urchin egg M-phase specific histone H1 kinase
27. Myt1: A membrane-associated inhibitory kinase that phosphorylates Cdc2 on both threonine-14 and tyrosine-15
28. Analysis of the early embryonic cell cycles of Xenopus; regulation of cell cycle length by Xe-wee1 and Mos
29. The Cell Cycle: An Introduction
30. Absence of Wee1 ensures the meiotic cell cycle in Xenopus oocytes
31. Universal control mechanism regulating onset of M-phase
32. In vitro disassembly of the nuclear lamina and M phase-specific phosphorylation of lamins by cdc2 kinase
33. The APC is dispensable for first meiotic anaphase in Xenopus oocytes
34. Isolation of a human cyclin cDNA: Evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2
35. The polo-like kinase P1x1 is required for activation of the phosphatase Cdc25C and cyclin B-Cdc2 in Xenopus oocytes
36. The coordination of centrosome reproduction with nuclear events during the cell cycle
37. Cyclin activation of p34cdc2
38. Control of mitosis by changes in the subcellular location of cyclin-B1-Cdk1 and Cdc25C
39. Polo-like kinase 1 phosphorylates cyclin B1 and targets it to the nucleus during prophase
40. All aboard the cyclin train: Subcellular trafficking of cyclins and their CDK partners
41. Functional analysis of the P box, a domain in cyclin B required for the activation of Cdc25