Genetic inhibition of PKA phosphorylation of RyR2 prevents dystrophic cardiomyopathy

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 29, 2010, Pages 13165-13170

  Sarma, Satyam ^a   Li, Na ^a   Van Oort, Ralph J ^a   Reynolds, Corey ^a   Skapura, Darlene G ^a   Wehrens, Xander H T ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Calcium; Cardiomyopathy; Dystrophin; Ryanodine receptor; Sarcoplasmic reticulum

Indexed keywords

ALANINE; CALCIUM ION; CYCLIC AMP DEPENDENT PROTEIN KINASE; RYANODINE RECEPTOR 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIOMYOPATHY; COMPARATIVE STUDY; CONTROLLED STUDY; DIASTOLE; DUCHENNE MUSCULAR DYSTROPHY; DYSTROPHIC CARDIOMYOPATHY; DYSTROPHY; ENZYME PHOSPHORYLATION; GENETIC ANALYSIS; HEART DILATATION; HEART FAILURE; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART MUSCLE FIBER MEMBRANE; HOMEOSTASIS; INCIDENCE; MOUSE; MUTATION; NONHUMAN; PRIORITY JOURNAL; X CHROMOSOME LINKED MUSCULAR DYSTROPHIC MOUSE;

AGING; ANIMALS; CALCIUM; CARDIOMYOPATHIES; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DEATH, SUDDEN; FIBROSIS; HEART FAILURE; INTRACELLULAR SPACE; ISOPROTERENOL; MICE; MICE, INBRED MDX; MUTATION; MYOCARDIUM; MYOCYTES, CARDIAC; PHOSPHORYLATION; PHOSPHOSERINE; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOLEMMA;

MUS;

EID: 77955592742     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1004509107     Document Type: Article

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