Inducible Expression of Active Protein Phosphatase-1 Inhibitor-1 Enhances Basal Cardiac Function and Protects Against Ischemia/Reperfusion Injury

Circulation Research

Volumn 104, Issue 8, 2009, Pages 1012-1020

  Nicolaou, Persoulla ^a   Rodriguez, Patricia ^a   Ren, Xiaoping ^a   Zhou, Xiaoyang ^a   Qian, Jiang ^a   Sadayappan, Sakthivel ^b   Mitton, Bryan ^a   Pathak, Anand ^a   Robbins, Jeffrey ^b   Hajjar, Roger J ^c   Jones, Keith ^a   Kranias, Evangelia G ^a,d  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b CINCINNATI CHILDREN S HOSPITAL RESEARCH FOUNDATION   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^d BIOMEDICAL RESEARCH FOUNDATION   (Greece)

Author keywords

ER stress; Ischemia; Phospholamban; Protein phosphatase 1 inhibitor 1; Reperfusion

Indexed keywords

CALCIUM ION; INHIBITOR PROTEIN; PHOSPHOLAMBAN; PROTEIN PHOSPHATASE 1 INHIBITOR 1; UNCLASSIFIED DRUG; CALCIUM BINDING PROTEIN; PHOSPHOPROTEIN PHOSPHATASE INHIBITOR 1; PROTEIN PHOSPHATASE INHIBITOR-1; SIGNAL PEPTIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CALCIUM TRANSPORT; CELL SURVIVAL; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; ENERGY METABOLISM; HEART CONTRACTION; HEART FUNCTION; HEART INFARCTION SIZE; HEART MUSCLE ISCHEMIA; HEART MUSCLE NECROSIS; HEART PROTECTION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; PROTEOMICS; RAT; REPERFUSION INJURY; SARCOPLASMIC RETICULUM; TRANSGENIC MOUSE; ANIMAL; CALCIUM SIGNALING; CONVALESCENCE; DISEASE MODEL; ENDOPLASMIC RETICULUM; ENZYMOLOGY; GENETICS; HEART INFARCTION; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE; METABOLISM; MUTATION; NECROSIS; PATHOLOGY; PATHOPHYSIOLOGY; PHOSPHORYLATION; PHYSIOLOGICAL STRESS; TIME; UPREGULATION;

ANIMALS; APOPTOSIS; CALCIUM SIGNALING; CALCIUM-BINDING PROTEINS; DISEASE MODELS, ANIMAL; ENDOPLASMIC RETICULUM; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, TRANSGENIC; MUTATION; MYOCARDIAL CONTRACTION; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; NECROSIS; PHOSPHORYLATION; PROTEOMICS; RECOVERY OF FUNCTION; SARCOPLASMIC RETICULUM; STRESS, PHYSIOLOGICAL; TIME FACTORS; UP-REGULATION; VENTRICULAR FUNCTION, LEFT;

EID: 65449131993     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.108.189811     Document Type: Article

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