-
1
-
-
40549119541
-
Incidence of fatal adverse drug reactions: A population based study
-
Wester K, Jonnson AK, Sigset O, Druid H, Hagg S: Incidence of fatal adverse drug reactions: a population based study. Br. J. Clin. Pharmacol. 65, 573-579 (2008).
-
(2008)
Br. J. Clin. Pharmacol.
, vol.65
, pp. 573-579
-
-
Wester, K.1
Jonnson, A.K.2
Sigset, O.3
Druid, H.4
Hagg, S.5
-
2
-
-
43449094338
-
Is personalized medicine fnally arriving?
-
Allison M: Is personalized medicine fnally arriving? Nat. Biotechnol. 26, 509-517 (2008).
-
(2008)
Nat. Biotechnol.
, vol.26
, pp. 509-517
-
-
Allison, M.1
-
3
-
-
1942421701
-
Pharmacogenetics of cytochrome P450 and its applications in drug therapy: The past, the present and future
-
Ingelman-Sundberg M: Pharmacogenetics of cytochrome P450 and its applications in drug therapy: the past, the present and future. Trends Pharmacol. Sci. 25, 193-200 (2004).
-
(2004)
Trends Pharmacol. Sci.
, vol.25
, pp. 193-200
-
-
Ingelman-Sundberg, M.1
-
4
-
-
0038294345
-
Pharmacogenetics of drug metabolizing enzymes: Importance for personalised medicine
-
Oscarson M: Pharmacogenetics of drug metabolizing enzymes: importance for personalised medicine. Clin. Chem. Lab. Med. 41, 573-580 (2003).
-
(2003)
Clin. Chem. Lab. Med.
, vol.41
, pp. 573-580
-
-
Oscarson, M.1
-
5
-
-
0034792584
-
Clinical relevance of genetic polymorphisms in the human CYP2C subfamily
-
Goldstein JA: Clinical relevance of genetic polymorphisms in the human CYP2C subfamily. Br. J. Clin. Pharmacol. 52, 349-355 (2001).
-
(2001)
Br. J. Clin. Pharmacol.
, vol.52
, pp. 349-355
-
-
Goldstein, J.A.1
-
6
-
-
28844491802
-
Drug-metabolizing enzymes: Evidence for clinical utility of pharmacogenomic tests
-
Andersson T, Flockhart DA, Goldstein DB et al.: Drug-metabolizing enzymes: evidence for clinical utility of pharmacogenomic tests. Clin. Pharmacol. Ther. 78, 559-581 (2005).
-
(2005)
Clin. Pharmacol. Ther.
, vol.78
, pp. 559-581
-
-
Andersson, T.1
Flockhart, D.A.2
Goldstein, D.B.3
-
7
-
-
76649115043
-
Pharmacogenetics of CYP2C19: Functional and clinical implications of a new variant CYP2C19*17
-
Li-Wan-Po A, Girard T, Farndon P, Cooley C, Lithgow J: Pharmacogenetics of CYP2C19: functional and clinical implications of a new variant CYP2C19*17. Br. J. Clin. Pharmacol. 69, 222-230 (2010).
-
(2010)
Br. J. Clin. Pharmacol.
, vol.69
, pp. 222-230
-
-
Li-Wan-Po, A.1
Girard, T.2
Farndon, P.3
Cooley, C.4
Lithgow, J.5
-
8
-
-
70649088031
-
Effects of genetic variation at the CYP2C19/CYP2C9 locus on pharmacokinetics of chlorcycloguanil in adult Gambians
-
Janha RE, Sisay-Joof F, Hamid-Adiamoh M et al.: Effects of genetic variation at the CYP2C19/CYP2C9 locus on pharmacokinetics of chlorcycloguanil in adult Gambians. Pharmacogenomics 10(9), 1423-1431 (2009).
-
(2009)
Pharmacogenomics
, vol.10
, Issue.9
, pp. 1423-1431
-
-
Janha, R.E.1
Sisay-Joof, F.2
Hamid-Adiamoh, M.3
-
9
-
-
59549103789
-
Pharmacogenetic variation at CYP2C9 CYP2C19 and CYP2D6 at global and microgeographic scales
-
Sistonen J, Fuselli S, Palo JU, Chauhan N, Padh H, Sajantila A: Pharmacogenetic variation at CYP2C9, CYP2C19 and CYP2D6 at global and microgeographic scales. Pharmacogenet. Genomics 19, 170-179 (2009).
-
(2009)
Pharmacogenet. Genomics
, vol.19
, pp. 170-179
-
-
Sistonen, J.1
Fuselli, S.2
Palo, J.U.3
Chauhan, N.4
Padh, H.5
Sajantila, A.6
-
10
-
-
77954765466
-
Elucidation of CYP2D6 genetic diversity in a unique African population: Implications for the future application of pharmacogenetics in the Xhosa population
-
Wright GEB, Niehaus DJH, Drögemöller BI, Koen L, Warnich L: Elucidation of CYP2D6 genetic diversity in a unique African population: implications for the future application of pharmacogenetics in the Xhosa population. Ann. Hum. Genet. 74(4), 340-350 (2010).
-
(2010)
Ann. Hum. Genet.
, vol.74
, Issue.4
, pp. 340-350
-
-
Geb, W.1
Djh, N.2
Drögemöller, B.I.3
Koen, L.4
Warnich, L.5
-
11
-
-
77949615790
-
New CYP2A6 gene deletion and conversion variants in a population of black African descent
-
Mwenifumbo JC, Zhou Q, Benowitz NL, Sellers EM, Tyndale RF: New CYP2A6 gene deletion and conversion variants in a population of black African descent. Pharmacogenomics 11(2), 189-198 (2010).
-
(2010)
Pharmacogenomics
, vol.11
, Issue.2
, pp. 189-198
-
-
Mwenifumbo, J.C.1
Zhou, Q.2
Benowitz, N.L.3
Sellers, E.M.4
Tyndale, R.F.5
-
12
-
-
66249116333
-
The genetic structure and history of Africans and African Americans
-
Tishkoff SA, Reed FA, Friedlaender FR et al.: The genetic structure and history of Africans and African Americans. Science 324, 1035-1044 (2009).
-
(2009)
Science
, vol.324
, pp. 1035-1044
-
-
Tishkoff, S.A.1
Reed, F.A.2
Friedlaender, F.R.3
-
13
-
-
0035039209
-
Genetic polymorphism of CYP2D6 and CYP2C19 in East-and Southern African populations including psychiatric patients
-
Dandara C, Masimirembwa CM, Magimba A et al.: Genetic polymorphism of CYP2D6 and CYP2C19 in East-and Southern African populations including psychiatric patients. Eur. J. Clin. Pharmacol. 57, 11-17 (2001).
-
(2001)
Eur. J. Clin. Pharmacol.
, vol.57
, pp. 11-17
-
-
Dandara, C.1
Masimirembwa, C.M.2
Magimba, A.3
-
14
-
-
65249102147
-
Novel variants of major drug-metabolizing enzyme genes in diverse African populations and their predicted functional effects
-
Matimba A, Del-Favero J, van Broeckhoven C, Masimirembwa C: Novel variants of major drug-metabolizing enzyme genes in diverse African populations and their predicted functional effects. Hum. Genomics 3, 169-190 (2009).
-
(2009)
Hum. Genomics
, vol.3
, pp. 169-190
-
-
Matimba, A.1
Del-Favero, J.2
Van Broeckhoven, C.3
Masimirembwa, C.4
-
15
-
-
0242698805
-
Bantu expansions: Re-envisioning a central problem of early African history
-
Ehret C: Bantu expansions: re-envisioning a central problem of early African history. Int. J. Afr. Hist. Stud. 34, 5-41 (2001).
-
(2001)
Int. J. Afr. Hist. Stud.
, vol.34
, pp. 5-41
-
-
Ehret, C.1
-
16
-
-
0036786750
-
Genetic substructure in South African Bantu-speakers: Evidence from autosomal DNA and Y-chromosome studies
-
Lane AB, Soodyall H, Arndt S et al.: Genetic substructure in South African Bantu-speakers: evidence from autosomal DNA and Y-chromosome studies. Am. J. Phys. Anthropol. 119, 175-185 (2002).
-
(2002)
Am. J. Phys. Anthropol.
, vol.119
, pp. 175-185
-
-
Lane, A.B.1
Soodyall, H.2
Arndt, S.3
-
17
-
-
77949897520
-
Genetic structure of a unique admixed population: Implications for medical research
-
Patterson N, Petersen DC, van der Ross RE et al.: Genetic structure of a unique admixed population: implications for medical research. Hum. Mol. Genet. 19, 411-419 (2010).
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 411-419
-
-
Patterson, N.1
Petersen, D.C.2
Van Der Ross, R.E.3
-
18
-
-
0024284028
-
A simple salting out procedure for extracting DNA from human nucleated cells
-
Miller SA, Dykes DD, Polesky HF: A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 16, 1215 (1988).
-
(1988)
Nucleic Acids Res.
, vol.16
, pp. 1215
-
-
Miller, S.A.1
Dykes, D.D.2
Polesky, H.F.3
-
19
-
-
0043122919
-
SIFT: Predicting amino acid changes that affect protein function
-
Ng PC, Henikoff S: SIFT: Predicting amino acid changes that affect protein function. Nucleic Acids Res. 31, 3812-3814 (2003).
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 3812-3814
-
-
Ng, P.C.1
Henikoff, S.2
-
20
-
-
0036713510
-
Human non-synonymous SNPs: Server and survey
-
Ramensky V, Bork P, Sunyaev S: Human non-synonymous SNPs: server and survey. Nucleic Acids Res. 30, 3894-3900 (2002).
-
(2002)
Nucleic Acids Res.
, vol.30
, pp. 3894-3900
-
-
Ramensky, V.1
Bork, P.2
Sunyaev, S.3
-
21
-
-
0025744474
-
Prediction of human mRNA donor and acceptor sites from the DNA sequence
-
Brunak S, Engelbrecht J, Knudsen S: Prediction of human mRNA donor and acceptor sites from the DNA sequence. J. Mol. Biol. 220, 49-65 (1991).
-
(1991)
J. Mol. Biol.
, vol.220
, pp. 49-65
-
-
Brunak, S.1
Engelbrecht, J.2
Knudsen, S.3
-
22
-
-
34547559084
-
SplicePort: An interactive splice-site analysis tool
-
Dogan RI, Getoor L, Wilbur WJ, Mount SM: SplicePort: an interactive splice-site analysis tool. Nucleic Acids Res. 35, 285-291 (2007).
-
(2007)
Nucleic Acids Res.
, vol.35
, pp. 285-291
-
-
Dogan, R.I.1
Getoor, L.2
Wilbur, W.J.3
Mount, S.M.4
-
23
-
-
0041853625
-
MATCH: A tool for searching transcription factor binding sites in DNA sequences
-
Kel AE, Gössling E, Reuter I, Cheremushkin E, Kel-Margoulis OV, Wingender E: MATCH: a tool for searching transcription factor binding sites in DNA sequences. Nucleic Acids Res. 31, 3576-3579 (2003).
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 3576-3579
-
-
Kel, A.E.1
Gössling, E.2
Reuter, I.3
Cheremushkin, E.4
Kel-Margoulis, O.V.5
Wingender, E.6
-
24
-
-
0028971143
-
MatInd and MatInspector: New fast and versatile tools for detection of consensus matches in nucleotide sequence data
-
Quandt K, Frech K, Karas H, Wingender E, Werner T: MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data. Nucleic Acids Res. 23, 4878-4884 (1995).
-
(1995)
Nucleic Acids Res.
, vol.23
, pp. 4878-4884
-
-
Quandt, K.1
Frech, K.2
Karas, H.3
Wingender, E.4
Werner, T.5
-
25
-
-
0042121256
-
Mfold web server for nucleic acid folding and hybridization prediction
-
Zuker M: Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res. 31, 3406-3415 (2003).
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 3406-3415
-
-
Zuker, M.1
-
26
-
-
13444269543
-
Haploview: Analysis and visualization of LD and haplotype maps
-
Barrett JC, Fry B, Maller J, Daly MJ: Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 21, 263-265 (2005).
-
(2005)
Bioinformatics
, vol.21
, pp. 263-265
-
-
Barrett, J.C.1
Fry, B.2
Maller, J.3
Daly, M.J.4
-
27
-
-
84892246340
-
Human cytochrome P450 enzymes
-
3rd Edition. Oritz de Montellano PR (Ed.). Plenum Publishers, NY, USA
-
Guengerich PF: Human cytochrome P450 enzymes. In: Cytochrome P450: Structure, Mechanism and Biochemistry. 3rd Edition. Oritz de Montellano PR (Ed.). Plenum Publishers, NY, USA, 378 (2005).
-
(2005)
Cytochrome P450: Structure, Mechanism and Biochemistry
, vol.378
-
-
Guengerich, P.F.1
-
28
-
-
77952300299
-
Impact of the CYP2C19*17 allele on the pharmacokinetics of omeprazole and pantoprazole in children: Evidence for a differential effect
-
Kearns GL, Leeder JS, Gaedigk A: Impact of the CYP2C19*17 allele on the pharmacokinetics of omeprazole and pantoprazole in children: evidence for a differential effect. Drug Metab. Dispos. 38(6), 894-897 (2010).
-
(2010)
Drug Metab. Dispos.
, vol.38
, Issue.6
, pp. 894-897
-
-
Kearns, G.L.1
Leeder, J.S.2
Gaedigk, A.3
-
29
-
-
41149086705
-
The CYP2D6 gene locus in South African Coloureds: Unique allele distributions, novel alleles and gene arrangements
-
Gaedigk A, Coetsee C: The CYP2D6 gene locus in South African Coloureds: unique allele distributions, novel alleles and gene arrangements. Eur. J. Clin. Pharmacol. 64, 465-475 (2008).
-
(2008)
Eur. J. Clin. Pharmacol.
, vol.64
, pp. 465-475
-
-
Gaedigk, A.1
Coetsee, C.2
-
30
-
-
0038561222
-
Sequence diversity and functional characterization of the 5́-regulatory region of human CYP2C19
-
Arefayene M, Skaar TC, Zhao X et al.: Sequence diversity and functional characterization of the 5́-regulatory region of human CYP2C19. Pharmacogenetics 13, 199-206 (2003).
-
(2003)
Pharmacogenetics
, vol.13
, pp. 199-206
-
-
Arefayene, M.1
Skaar, T.C.2
Zhao, X.3
-
31
-
-
70450157394
-
The transcriptional regulation of the human CYP2C genes
-
Chen Y, Goldstein JA: The transcriptional regulation of the human CYP2C genes. Curr. Drug Metab. 10, 567-578 (2009).
-
(2009)
Curr. Drug Metab.
, vol.10
, pp. 567-578
-
-
Chen, Y.1
Goldstein, J.A.2
-
32
-
-
0030068331
-
Nuclear transcription factor Oct-1 binds to the 5́ upstream region of CYP1A1 and negatively regulates its expression
-
Bhat R, Weaver JA, Sterling KM, Bresnick E: Nuclear transcription factor Oct-1 binds to the 5́ upstream region of CYP1A1 and negatively regulates its expression. Int. J. Biochem. Cell Biol. 28, 217-227 (1996).
-
(1996)
Int. J. Biochem. Cell Biol.
, vol.28
, pp. 217-227
-
-
Bhat, R.1
Weaver, J.A.2
Sterling, K.M.3
Bresnick, E.4
-
33
-
-
34249283750
-
Regulation of the rat cyp2A4 gene promoter by c-Jun and octamer binding protein-1
-
Fiala-Beer E, Lee AC, Murray M: Regulation of the rat cyp2A4 gene promoter by c-Jun and octamer binding protein-1. Int. J. Biochem. Cell. Biol. 39, 1235-1247 (2007).
-
(2007)
Int. J. Biochem. Cell. Biol.
, vol.39
, pp. 1235-1247
-
-
Fiala-Beer, E.1
Lee, A.C.2
Murray, M.3
-
34
-
-
77951914218
-
The transcription factor GATA-4 regulates cytochrome P4502C19 gene expression
-
Mwinyi J, Hofmann Y, Pedersen RS et al.: The transcription factor GATA-4 regulates cytochrome P4502C19 gene expression. Life Sci. 86, 699-706 (2010).
-
(2010)
Life Sci.
, vol.86
, pp. 699-706
-
-
Mwinyi, J.1
Hofmann, Y.2
Pedersen, R.S.3
-
35
-
-
12244261584
-
Identifcation and functional characterization of new potentially defective alleles of human CYP2C19
-
Blaisdell J, Mohrenweiser H, Jackson J et al.: Identifcation and functional characterization of new potentially defective alleles of human CYP2C19. Pharmacogenetics 12, 703-711 (2002).
-
(2002)
Pharmacogenetics
, vol.12
, pp. 703-711
-
-
Blaisdell, J.1
Mohrenweiser, H.2
Jackson, J.3
-
36
-
-
41449116171
-
Misclassifcation of allele CYP2C19*10 as CYP2C19*2 by a commonly used PCR-RFLP procedure
-
Rasmussen H, Werge T: Misclassifcation of allele CYP2C19*10 as CYP2C19*2 by a commonly used PCR-RFLP procedure. Genet. Test. 12, 57-58 (2008).
-
(2008)
Genet. Test.
, vol.12
, pp. 57-58
-
-
Rasmussen, H.1
Werge, T.2
-
37
-
-
70749149366
-
Clopidogrel pharmacogenomics and risk of inadequate platelet inhibition: US FDA recommendations
-
Ellis KJ, Stouffer GA, McLeod HL, Lee CR: Clopidogrel pharmacogenomics and risk of inadequate platelet inhibition: US FDA recommendations. Pharmacogenomics 10, 1799-1817 (2009).
-
(2009)
Pharmacogenomics
, vol.10
, pp. 1799-1817
-
-
Ellis, K.J.1
Stouffer, G.A.2
McLeod, H.L.3
Lee, C.R.4
-
38
-
-
40049098725
-
Adverse drug reactions in adult medical inpatients in a South African hospital serving a community with a high HIV/AIDS prevalence: Prospective observational study
-
Mehta U, Durrheim DN, Blockman M, Kredo T, Gounden R, Barnes KI: Adverse drug reactions in adult medical inpatients in a South African hospital serving a community with a high HIV/AIDS prevalence: prospective observational study. Br. J. Clin. Pharmacol. 65, 396-406 (2007).
-
(2007)
Br. J. Clin. Pharmacol.
, vol.65
, pp. 396-406
-
-
Mehta, U.1
Durrheim, D.N.2
Blockman, M.3
Kredo, T.4
Gounden, R.5
Barnes, K.I.6
-
39
-
-
77954461644
-
Variability in drug metabolizing enzyme activity in HIV-infected patients
-
Jones AE, Brown KC, Werner RE et al.: Variability in drug metabolizing enzyme activity in HIV-infected patients. Eur. J. Clin. Pharmacol. 66(5), 475-485 (2010).
-
(2010)
Eur. J. Clin. Pharmacol.
, vol.66
, Issue.5
, pp. 475-485
-
-
Jones, A.E.1
Brown, K.C.2
Werner, R.E.3
-
40
-
-
48949119312
-
Genetic polymorphism analysis of CYP2C19 in Chinese Han populations from different geographic areas of mainland China
-
Chen L, Qin S, Xie J et al.: Genetic polymorphism analysis of CYP2C19 in Chinese Han populations from different geographic areas of mainland China. Pharmacogenomics 9, 691-702 (2008).
-
(2008)
Pharmacogenomics
, vol.9
, pp. 691-702
-
-
Chen, L.1
Qin, S.2
Xie, J.3
-
41
-
-
62649146991
-
Need for reassessment of reported CYP2C19 allele frequencies in various populations in view of CYP2C19*17 discovery: The case of Greece
-
Ragia G, Arvanitidis KI, Tavridou A, Manolopoulos VG: Need for reassessment of reported CYP2C19 allele frequencies in various populations in view of CYP2C19*17 discovery: the case of Greece. Pharmacogenomics 10, 43-49 (2009).
-
(2009)
Pharmacogenomics
, vol.10
, pp. 43-49
-
-
Ragia, G.1
Arvanitidis, K.I.2
Tavridou, A.3
Manolopoulos, V.G.4
|