Regulation of the rat CYP4A2 gene promoter by c-Jun and octamer binding protein-1

International Journal of Biochemistry and Cell Biology

Volumn 39, Issue 6, 2007, Pages 1235-1247

  Fiala Beer, Eva ^a   Lee, Andy C ^a   Murray, Michael ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Activator protein 1; Cytochrome P450 4A2; Gene transactivation; Octamer binding protein 1

Indexed keywords

ALKANE 1 MONOOXYGENASE; ARACHIDONIC ACID; CYTOCHROME P450 4A; DNA; LIPID; NUCLEAR PROTEIN; OCTAMER TRANSCRIPTION FACTOR 1; PEROXISOME PROLIFERATOR; PROTEIN ANTIBODY; PROTEIN C JUN; TRANSCRIPTION FACTOR AP 1;

ANIMAL CELL; ARTICLE; CHROMATIN IMMUNOPRECIPITATION; CONSENSUS SEQUENCE; CONTROLLED STUDY; CYP4A2 GENE; ENZYME INDUCTION; GEL MOBILITY SHIFT ASSAY; GENE; GENE CONTROL; GENE EXPRESSION; MOLECULAR CLOCK; NONHUMAN; NUCLEOTIDE SEQUENCE; PROMOTER REGION; RAT; TRANSACTIVATION;

ANIMALS; BASE SEQUENCE; CELL LINE, TUMOR; CYTOCHROME P-450 ENZYME SYSTEM; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; LUCIFERASES; OCTAMER TRANSCRIPTION FACTOR-1; OLIGONUCLEOTIDES; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-JUN; RATS; RECOMBINANT FUSION PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANS-ACTIVATION (GENETICS); TRANSFECTION;

RATTUS;

EID: 34249283750     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2007.03.019     Document Type: Article

References (47)

1. Andersen B., and Rosenfeld M.G. POU domain factors in the neuroendocrine system: Lessons from developmental biology provide insights into human disease. Endocr. Rev. 22 (2001) 2-35
2. Angel P.E., and Herrlich P.A. The FOS and JUN families of transcription factors (1994), CRC Press, Boca Raton
3. Angel P., Imagawa M., Chiu R., Stein B., Imbra R.J., Rahmsdorf H.J., et al. Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor. Cell 49 (1987) 729-739
4. Angel P., and Karin M. The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochim. Biophys. Acta 1072 (1991) 129-157
5. Barclay T.B., Peters J.M., Sewer M.B., Ferrari L., Gonzalez F.J., and Morgan E.T. Modulation of cytochrome P-450 gene expression in endotoxemic mice is tissue specific and peroxisome proliferator-activated receptor-α dependent. J. Pharmacol. Exp. Ther. 290 (1999) 1250-1257
6. Bell D.R., Plant N.J., Rider C.G., Na L., Brown S., Ateitalla I., et al. Species-specific induction of cytochrome P-450 4A RNAs: PCR cloning of partial guinea-pig, human and mouse CYP4A cDNAs. Biochem. J. 94 (1993) 173-180
7. Bhat R., Weaver J.A., Sterling K.M., and Bresnick E. Nuclear transcription factor Oct-1 binds to the 5′-upstream region of CYP1A1 and negatively regulates its expression. Int. J. Biochem. Cell Biol. 28 (1996) 217-227
8. Boulon S., Dantonel J.C., Binet V., Vie A., Blanchard J.M., Hipskind R.A., et al. Oct-1 potentiates CREB-driven cyclin D1 promoter activation via a phospho-CREB- and CREB binding protein-independent mechanism. Mol. Cell. Biol. 22 (2002) 7769-7779
9. Coyle A.T., and Kinsella B.T. Characterization of promoter 3 of the human thromboxane A receptor gene. A functional AP-1 and octamer motif are required for basal promoter activity. FEBS J. 272 (2005) 1036-1053
10. Davey H.W., Park S.H., Grattan D.R., McLachlan M.J., and Waxman D.J. STAT5b-deficient mice are growth hormone pulse-resistant. Role of STAT5b in sex-specific liver P450 expression. J. Biol. Chem. 274 (1999) 35331-35336
11. Fradette C., and du Souich P. Hypoxia-inducible factor-1 and activator protein-1 modulate the upregulation of CYP3A6 induced by hypoxia. Br. J. Pharmacol. 140 (2003) 1146-1154
12. 2+ current. J. Physiol. 507 (1998) 771-781
13. Gibson G.G., Orton T.C., and Tamburini P.P. Cytochrome P-450 induction by clofibrate. Purification and properties of a hepatic cytochrome P-450 relatively specific for the 12- and 11-hydroxylation of dodecanoic acid (lauric acid). Biochem. J. 203 (1982) 161-188
14. Guengerich F.P., Wu Z.L., and Bartleson C.J. Function of human cytochrome P450s: Characterization of the orphans. Biochem. Biophys. Res. Commun. 338 (2005) 465-469
15. Herzig T.C., Jobe S.M., Aoki H., Molkentin J.D., Cowley Jr. A.W., Izumo S., et al. Angiotensin II type1a receptor gene expression in the heart: AP-1 and GATA-4 participate in the response to pressure overload. Proc. Natl. Acad. Sci. U.S.A. 94 (1997) 7543-7548
16. Ip E., Farrell G.C., Robertson G., Hall P., Kirsch R., and Leclercq I. Central role of PPARα-dependent hepatic lipid turnover in dietary steatohepatitis in mice. Hepatology 38 (2003) 123-132
17. Ito O., Alonso-Galicia M., Hopp K.A., and Roman R.J. Localization of cytochrome P-450 4A isoforms along the rat nephron. Am. J. Physiol. 274 (1998) F395-F404
18. Johnson E.F., Palmer C.N., Griffin K.J., and Hsu M.H. Role of the peroxisome proliferator-activated receptor in cytochrome P450 4A gene regulation. FASEB J. 10 (1996) 1241-1248
19. Kambe F., Tsukahara S., Kato T., and Seo H. The POU-domain protein Oct-1 is widely expressed in adult rat organs. Biochim. Biophys. Acta 1171 (1993) 307-310
20. Kimura S., Hanioka N., Matsunaga E., and Gonzalez F.J. The rat clofibrate-inducible CYP4A gene subfamily. I. Complete intron and exon sequence of the CYP4A1 and CYP4A2 genes, unique exon organization, and identification of a conserved 19-bp upstream element. DNA 8 (1989) 503-516
21. Kimura S., Hardwick J.P., Kozak C.A., and Gonzalez F.J. The rat clofibrate-inducible CYP4A subfamily. II. cDNA sequence of IVA3, mapping of the Cyp4a locus to mouse chromosome 4, and coordinate and tissue-specific regulation of the CYP4A genes. DNA 8 (1989) 517-525
22. Kroetz D.L., Huse L.M., Thuresson A., and Grillo M.P. Developmentally regulated expression of the CYP4A genes in the spontaneously hypertensive rat kidney. Mol. Pharmacol. 52 (1997) 362-372
23. Lin H.K., and Penning T.M. Cloning, sequencing, and functional analysis of the 5′-flanking region of the rat 3α-hydroxysteroid/dihydrodiol dehydrogenase gene. Cancer Res. 55 (1995) 4105-4113
24. Lowry O.H., Rosenbrough N.J., Farr A.L., and Randell R.J. Protein measurement with the folin phenol reagent. J. Biol. Chem. 193 (1951) 265-270
25. Marden N.Y., Fiala-Beer E., Xiang S.H., and Murray M. Role of activator protein-1 in the down-regulation of the human CYP2J2 gene in hypoxia. Biochem. J. 373 (2003) 669-680
26. Marden N.Y., and Murray M. Characterization of a c-Jun-responsive module in the 5′-flank of the human CYP2J2 gene that regulates transactivation. Biochem. J. 391 (2005) 631-640
27. Marji J.S., Wang M.H., and Laniado-Schwartzman M. Cytochrome P-450 4A isoform expression and 20-HETE synthesis in renal preglomerular arteries. Am. J. Physiol. 283 (2002) F60-F67
28. Murray M., Sefton R.M., Croft K.D., and Butler A.M. Differential regulation of endobiotic-oxidizing cytochromes P450 in vitamin A-deficient male rat liver. Br. J. Pharmacol. 134 (2001) 1487-1497
29. Omata K., Abraham N.G., and Schwartzman M.L. Renal cytochrome P-450-arachidonic acid metabolism: Localization and hormonal regulation in SHR. Am. J. Physiol. 262 (1992) F591-F599
30. Ortiz de Montellano P.R., and De Voss J.J. Substrate oxidation by cytochrome P450 enzymes. In: Ortiz de Montellano P.R. (Ed). Cytochrome P450: Structure, mechanism, and Biochemistry. 3rd Ed. (2005), Kluwer Academic/Plenum Publishers, New York 183-245
31. Peters J.M., Zhou Y.C., Ram P.A., Lee S.S., Gonzalez F.J., and Waxman D.J. Peroxisome proliferator-activated receptor-α required for gene induction by dehydroepiandrosterone-3β-sulfate. Mol. Pharmacol. 50 (1996) 67-74
32. Pfeuffer I., Klein-Hessling S., Heinfling A., Chuvpilo S., Escher C., Brabletz T., et al. Octamer factors exert a dual effect on the IL-2 and IL-4 promoters. J. Immunol. 153 (1994) 5572-5585
33. Quandt K., Frech K., Karas H., Wingender E., and Werner T. MatInd and MatInspector: New fast and versatile tools for detection of consensus matches in nucleotide sequence data. Nucl. Acids Res. 23 (1995) 4878-4884
34. Roman R.J. P-450 metabolites of arachidonic acid in the control of cardiovascular function. Physiol. Rev. 82 (2002) 131-185
35. Rupec R.A., and Baeuerle P.A. The genomic response of tumor cells to hypoxia and reoxygenation. Differential activation of transcription factors AP-1 and NF-κB. Eur. J. Biochem. 234 (1995) 632-640
36. Schreiber E., Matthias P., Müller M.M., and Schaffner W. Rapid detection of octamer binding proteins with 'mini-extracts' prepared from a small number of cells. Nucl. Acids Res. 17 (1989) 6419
37. Sterling K., and Bresnick E. Oct-1 transcription factor is a negative regulator of rat CYP1A1 expression via an octamer sequence in its negative regulatory element. Mol. Pharmacol. 49 (1996) 329-337
38. Stromstedt M., Warner M., and Gustafsson J.-A. Cytochrome P450s of the 4A subfamily in the brain. J. Neurochem. 63 (1994) 671-676
39. Sturm R., Baumruker T., Franza Jr. B.R., and Herr W. A 100-kD HeLa cell octamer binding protein (OBP100) interacts differently with two separate octamer-related sequences within the SV40 enhancer. Genes Dev. 1 (1987) 1147-1160
40. Su G.M., Fiala-Beer E., Weber J., Jahn D., Robertson G.R., and Murray M. Pretranslational upregulation of microsomal CYP4A in rat liver by intake of a high-sucrose, lipid-devoid diet containing orotic acid. Biochem. Pharmacol. 69 (2005) 709-717
41. Sundseth S.S., and Waxman D.J. Sex-dependent expression and clofibrate inducibility of cytochrome P450 4A fatty acid ω-hydroxylases. Male specificity of liver and kidney CYP4A2 mRNA and tissue-specific regulation by growth hormone and testosterone. J. Biol. Chem. 267 (1992) 3915-3921
42. Thomas M.A., Mordvinov V.A., and Sanderson C.J. The activity of the human interleukin-5 conserved lymphokine element 0 is regulated by octamer factors in human cells. Eur. J. Biochem. 265 (1999) 300-307
43. Thum T., Haverich A., and Borlak J. Cellular dedifferentiation of endothelium is linked to activation and silencing of certain nuclear transcription factors: Implications for endothelial dysfunction and vascular biology. FASEB J. 14 (2000) 740-751
44. Webb S.J., Xiao G.H., Geoghegan T.E., and Prough R.A. Regulation of CYP4A expression in rat by dehydroepiandrosterone and thyroid hormone. Mol. Pharmacol. 49 (1996) 276-287
45. Witt O., Albig W., and Doenecke D. Transcriptional regulation of the human replacement histone gene H3. 3B. FEBS Lett. 408 (1997) 255-260
46. Wolberger C. Multiprotein-DNA complexes in transcriptional regulation. Ann. Rev. Biophys. Biomol. Struct. 28 (1999) 29-56
47. Zhong S.P., Ma W.Y., Quealy J.A., Zhang Y., and Dong Z. Organ-specific distribution of AP-1 in AP-1 luciferase transgenic mice during the maturation process. Am. J. Physiol. 280 (2001) R376-R381