메뉴 건너뛰기




Volumn 3, Issue 1, 2010, Pages 79-85

Update and developments in the treatment of glioblastoma multiforme - focus on bevacizumab

Author keywords

Angiogenesis; Avastin; Bevacizumab; Cancer; Glioblastoma; Glioma; Vascular endothelial growth factor

Indexed keywords

BEVACIZUMAB; CARBOPLATIN; CARMUSTINE; EPIDERMAL GROWTH FACTOR RECEPTOR; IRINOTECAN; PROTEIN P53; RETINOBLASTOMA PROTEIN; TEMOZOLOMIDE; VASCULOTROPIN;

EID: 77955582939     PISSN: None     EISSN: 11787066     Source Type: Book Series    
DOI: None     Document Type: Review
Times cited : (4)

References (72)
  • 1
    • 20044366163 scopus 로고    scopus 로고
    • Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
    • Stupp R, Mason WP, van den Bent MJ, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med. 2005;352:987-996.
    • (2005) N Engl J Med , vol.352 , pp. 987-996
    • Stupp, R.1    Mason, W.P.2    van den Bent, M.J.3
  • 2
    • 0037245929 scopus 로고    scopus 로고
    • Targeted molecular therapy of GBM
    • Mischel PS, Cloughesy TF. Targeted molecular therapy of GBM. Brain Pathol. 2003;13:52-61.
    • (2003) Brain Pathol , vol.13 , pp. 52-61
    • Mischel, P.S.1    Cloughesy, T.F.2
  • 3
    • 54549108740 scopus 로고    scopus 로고
    • Comprehensive genomic characterization defines human glioblastoma genes and core pathways
    • Cancer Genome Atlas Research Network
    • Cancer Genome Atlas Research Network. Comprehensive genomic characterization defines human glioblastoma genes and core pathways. Nature. 2008;455:1061-1068.
    • (2008) Nature , vol.455 , pp. 1061-1068
  • 4
    • 0026521394 scopus 로고
    • Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N- and/or C-terminal tails
    • Ekstrand AJ, Sugawa N, James CD, Collins VP. Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N- and/or C-terminal tails. Proc Natl Acad Sci U S A. 1992;89:4309-4313.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 4309-4313
    • Ekstrand, A.J.1    Sugawa, N.2    James, C.D.3    Collins, V.P.4
  • 5
    • 0034163550 scopus 로고    scopus 로고
    • Diversity and frequency of epidermal growth factor receptor mutations in human glioblastomas
    • Frederick L, Wang XY, Eley G, James CD. Diversity and frequency of epidermal growth factor receptor mutations in human glioblastomas. Cancer Res. 2000;60:1383-1387.
    • (2000) Cancer Res , vol.60 , pp. 1383-1387
    • Frederick, L.1    Wang, X.Y.2    Eley, G.3    James, C.D.4
  • 6
    • 0030797470 scopus 로고    scopus 로고
    • Association of EGFR gene amplification and CDKN2 (p16/MTS1) gene deletion in glioblastoma multiforme
    • Hayashi Y, Ueki K, Waha A, Wiestler OD, Louis DN, von Deimling A. Association of EGFR gene amplification and CDKN2 (p16/MTS1) gene deletion in glioblastoma multiforme. Brain Pathol. 1997;7: 871-875
    • (1997) Brain Pathol , vol.7 , pp. 871-875
    • Hayashi, Y.1    Ueki, K.2    Waha, A.3    Wiestler, O.D.4    Louis, D.N.5    von Deimling, A.6
  • 7
    • 0032601166 scopus 로고    scopus 로고
    • Primary and secondary glioblastomas: From concept to clinical diagnosis
    • Kleihues P, Ohgaki H. Primary and secondary glioblastomas: from concept to clinical diagnosis. Neuro Oncol. 1999;1:44-51.
    • (1999) Neuro Oncol , vol.1 , pp. 44-51
    • Kleihues, P.1    Ohgaki, H.2
  • 8
    • 0034947649 scopus 로고    scopus 로고
    • EGF mutant receptor vIII as a molecular target in cancer therapy
    • Kuan CT, Wikstrand CJ, Bigner DD. EGF mutant receptor vIII as a molecular target in cancer therapy. Endocr Relat Cancer. 2001;8:83-96.
    • (2001) Endocr Relat Cancer , vol.8 , pp. 83-96
    • Kuan, C.T.1    Wikstrand, C.J.2    Bigner, D.D.3
  • 9
    • 0035142469 scopus 로고    scopus 로고
    • Aberrant receptor signaling in human malignant gliomas: Mechanisms and therapeutic implications
    • Nagane M, Lin H, Cavenee WK, Huang HJ. Aberrant receptor signaling in human malignant gliomas: mechanisms and therapeutic implications. Cancer Lett. 2001;162 Suppl:S17-S21.
    • (2001) Cancer Lett , vol.162 , Issue.SUPPL.
    • Nagane, M.1    Lin, H.2    Cavenee, W.K.3    Huang, H.J.4
  • 10
    • 0028146767 scopus 로고
    • A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity
    • Nishikawa R, Ji XD, Harmon RC, et al. A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity. Proc Natl Acad Sci U S A. 1994;91:7727-7731.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 7727-7731
    • Nishikawa, R.1    Ji, X.D.2    Harmon, R.C.3
  • 11
    • 0035880788 scopus 로고    scopus 로고
    • PTEN mutation, EGFR amplification, and outcome in patients with anaplastic astrocytoma and glioblastoma multiforme
    • Smith JS, Tachibana I, Passe SM, et al. PTEN mutation, EGFR amplification, and outcome in patients with anaplastic astrocytoma and glioblastoma multiforme. J Natl Cancer Inst. 2001;93: 1246-1256.
    • (2001) J Natl Cancer Inst , vol.93 , pp. 1246-1256
    • Smith, J.S.1    Tachibana, I.2    Passe, S.M.3
  • 12
    • 0030017885 scopus 로고    scopus 로고
    • Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas
    • discussion 23-24
    • Watanabe K, Tachibana O, Sata K, Yonekawa Y, Kleihues P, Ohgaki H. Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas. Brain Pathol. 1996;6:217-223; discussion 23-24.
    • (1996) Brain Pathol , vol.6 , pp. 217-223
    • Watanabe, K.1    Tachibana, O.2    Sata, K.3    Yonekawa, Y.4    Kleihues, P.5    Ohgaki, H.6
  • 13
    • 7144261725 scopus 로고    scopus 로고
    • The class III variant of the epidermal growth factor receptor (EGFRvIII): Characterization and utilization as an immunotherapeutic target
    • Wikstrand CJ, Reist CJ, Archer GE, Zalutsky MR, Bigner DD. The class III variant of the epidermal growth factor receptor (EGFRvIII): characterization and utilization as an immunotherapeutic target. J Neurovirol. 1998;4:148-158.
    • (1998) J Neurovirol , vol.4 , pp. 148-158
    • Wikstrand, C.J.1    Reist, C.J.2    Archer, G.E.3    Zalutsky, M.R.4    Bigner, D.D.5
  • 14
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-Kinase AKT pathway in human cancer
    • Vivanco I, Sawyers CL. The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat Rev Cancer. 2002;2:489-501.
    • (2002) Nat Rev Cancer , vol.2 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 17
    • 0034905234 scopus 로고    scopus 로고
    • Synergy of the protein farnesyltransferase inhibitor SCH66336 and cisplatin in human cancer cell lines
    • Adjei AA, Davis JN, Bruzek LM, Erlichman C, Kaufmann SH. Synergy of the protein farnesyltransferase inhibitor SCH66336 and cisplatin in human cancer cell lines. Clin Cancer Res. 2001;7: 1438-1445.
    • (2001) Clin Cancer Res , vol.7 , pp. 1438-1445
    • Adjei, A.A.1    Davis, J.N.2    Bruzek, L.M.3    Erlichman, C.4    Kaufmann, S.H.5
  • 18
    • 0032763824 scopus 로고    scopus 로고
    • Expression of activated epidermal growth factor receptors, Ras-guanosine triphosphate, and mitogen-activated protein kinase in human glioblastoma multiforme specimens
    • Feldkamp MM, Lala P, Lau N, Roncari L, Guha A. Expression of activated epidermal growth factor receptors, Ras-guanosine triphosphate, and mitogen-activated protein kinase in human glioblastoma multiforme specimens. Neurosurgery. 1999;45:1442-1453.
    • (1999) Neurosurgery , vol.45 , pp. 1442-1453
    • Feldkamp, M.M.1    Lala, P.2    Lau, N.3    Roncari, L.4    Guha, A.5
  • 19
    • 0029397307 scopus 로고
    • The p53 gene and its role in human brain tumors
    • Bogler O, Huang HJ, Kleihues P, Cavenee WK. The p53 gene and its role in human brain tumors. Glia. 1995;15:308-327.
    • (1995) Glia , vol.15 , pp. 308-327
    • Bogler, O.1    Huang, H.J.2    Kleihues, P.3    Cavenee, W.K.4
  • 20
    • 0026649648 scopus 로고
    • The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
    • Momand J, Zambetti GP, Olson DC, George D, Levine AJ. The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell. 1992;69:1237-1245.
    • (1992) Cell , vol.69 , pp. 1237-1245
    • Momand, J.1    Zambetti, G.P.2    Olson, D.C.3    George, D.4    Levine, A.J.5
  • 22
    • 0032549704 scopus 로고    scopus 로고
    • The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
    • Pomerantz J, Schreiber-Agus N, Liegeois NJ, et al. The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53. Cell. 1998;92:713-723.
    • (1998) Cell , vol.92 , pp. 713-723
    • Pomerantz, J.1    Schreiber-Agus, N.2    Liegeois, N.J.3
  • 23
    • 0025040367 scopus 로고
    • Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53
    • Mercer WE, Shields MT, Amin M, et al. Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53. Proc Natl Acad Sci U S A. 1990;87:6166-6170.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 6166-6170
    • Mercer, W.E.1    Shields, M.T.2    Amin, M.3
  • 24
    • 34250877865 scopus 로고    scopus 로고
    • Genetic Pathways to Primary and Secondary Glioblastoma
    • Ohgaki H, Kleihues P. Genetic Pathways to Primary and Secondary Glioblastoma. Am J Pathol. 2007;170:1445-1453.
    • (2007) Am J Pathol , vol.170 , pp. 1445-1453
    • Ohgaki, H.1    Kleihues, P.2
  • 25
    • 0033564697 scopus 로고    scopus 로고
    • CDK inhibitors: Positive and negative regulators of G1-phase progression
    • Sherr CJ, Roberts JM. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev. 1999;13:1501-1512.
    • (1999) Genes Dev , vol.13 , pp. 1501-1512
    • Sherr, C.J.1    Roberts, J.M.2
  • 26
    • 43249095919 scopus 로고    scopus 로고
    • Tumor Angiogenesis
    • Kerbel RS. Tumor Angiogenesis. N Engl J Med. 2008;358:2039-2049.
    • (2008) N Engl J Med , vol.358 , pp. 2039-2049
    • Kerbel, R.S.1
  • 27
    • 33344474964 scopus 로고    scopus 로고
    • Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis
    • Shibuya M, Claesson-Welsh L. Signal transduction by VEGF receptors in regulation of angiogenesis and lymphangiogenesis. Exp Cell Res. 2006;312:549-560.
    • (2006) Exp Cell Res , vol.312 , pp. 549-560
    • Shibuya, M.1    Claesson-Welsh, L.2
  • 28
    • 0036782278 scopus 로고    scopus 로고
    • VEGF and the quest for tumour angiogenesis factors
    • Ferrara N. VEGF and the quest for tumour angiogenesis factors. Nat Rev Cancer. 2002;2:795-803.
    • (2002) Nat Rev Cancer , vol.2 , pp. 795-803
    • Ferrara, N.1
  • 29
    • 14644440555 scopus 로고    scopus 로고
    • Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis
    • Hicklin DJ, Ellis LM. Role of the vascular endothelial growth factor pathway in tumor growth and angiogenesis. J Clin Oncol. 2005;23:1011-1027.
    • (2005) J Clin Oncol , vol.23 , pp. 1011-1027
    • Hicklin, D.J.1    Ellis, L.M.2
  • 30
    • 0035108298 scopus 로고    scopus 로고
    • Glomeruloid microvascular proliferation orchestrated by VPF/VEGF: A new world of angiogenesis research
    • Brat DJ, Van Meir EG. Glomeruloid microvascular proliferation orchestrated by VPF/VEGF: a new world of angiogenesis research. Am J Pathol. 2001;158:789-796.
    • (2001) Am J Pathol , vol.158 , pp. 789-796
    • Brat, D.J.1    van Meir, E.G.2
  • 31
    • 0032515047 scopus 로고    scopus 로고
    • Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation
    • Gerber HP, McMurtrey A, Kowalski J, et al. Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation. J Biol Chem. 1998;273:30336-30343.
    • (1998) J Biol Chem , vol.273 , pp. 30336-30343
    • Gerber, H.P.1    McMurtrey, A.2    Kowalski, J.3
  • 33
    • 0026502754 scopus 로고
    • Binding sites for vascular endothelial growth factor are localized on endothelial cells in adult rat tissues
    • Jakeman LB, Winer J, Bennett GL, Altar CA, Ferrara N. Binding sites for vascular endothelial growth factor are localized on endothelial cells in adult rat tissues. J Clin Invest. 1992;89:244-53.
    • (1992) J Clin Invest , vol.89 , pp. 244-253
    • Jakeman, L.B.1    Winer, J.2    Bennett, G.L.3    Altar, C.A.4    Ferrara, N.5
  • 34
    • 33745976468 scopus 로고    scopus 로고
    • Current status of angiogenesis inhibitors combined with radiation therapy
    • Nieder C, Wiedenmann N, Andratschke N, Molls M. Current status of angiogenesis inhibitors combined with radiation therapy. Cancer Treat Rev. 2006;32:348-364.
    • (2006) Cancer Treat Rev , vol.32 , pp. 348-364
    • Nieder, C.1    Wiedenmann, N.2    Andratschke, N.3    Molls, M.4
  • 35
    • 0035893737 scopus 로고    scopus 로고
    • Simultaneous inhibition of glioma angiogenesis, cell proliferation, and invasion by a naturally occurring fragment of human metalloproteinase-2
    • Bello L, Lucini V, Carrabba G, et al. Simultaneous inhibition of glioma angiogenesis, cell proliferation, and invasion by a naturally occurring fragment of human metalloproteinase-2. Cancer Res. 2001;61:8730-8736.
    • (2001) Cancer Res , vol.61 , pp. 8730-8736
    • Bello, L.1    Lucini, V.2    Carrabba, G.3
  • 36
    • 0036164810 scopus 로고    scopus 로고
    • Angiogenesis in the central nervous system: A role for vascular endothelial growth factor/vascular permeability factor and tenascin-C. Common molecular effectors in cerebral neoplastic and non-neoplastic "angiogenic diseases"
    • Zagzag D, Capo V. Angiogenesis in the central nervous system: a role for vascular endothelial growth factor/vascular permeability factor and tenascin-C. Common molecular effectors in cerebral neoplastic and non-neoplastic "angiogenic diseases". Histol Histopathol. 2002;17:301-321.
    • (2002) Histol Histopathol , vol.17 , pp. 301-321
    • Zagzag, D.1    Capo, V.2
  • 37
    • 34249014416 scopus 로고    scopus 로고
    • Relationship between survival and edema in malignant gliomas: Role of vascular endothelial growth factor and neuronal pentraxin 2
    • Carlson MR, Pope WB, Horvath S, et al. Relationship between survival and edema in malignant gliomas: role of vascular endothelial growth factor and neuronal pentraxin 2. Clin Cancer Res. 2007;13:2592-2598.
    • (2007) Clin Cancer Res , vol.13 , pp. 2592-2598
    • Carlson, M.R.1    Pope, W.B.2    Horvath, S.3
  • 38
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med. 2004;350:2335-2342.
    • (2004) N Engl J Med , vol.350 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3
  • 39
    • 2942657615 scopus 로고    scopus 로고
    • Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer
    • Johnson DH, Fehrenbacher L, Novotny WF, et al. Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer. J Clin Oncol. 2004;22:2184-2191.
    • (2004) J Clin Oncol , vol.22 , pp. 2184-2191
    • Johnson, D.H.1    Fehrenbacher, L.2    Novotny, W.F.3
  • 40
    • 37549040613 scopus 로고    scopus 로고
    • Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer
    • Miller K, Wang M, Gralow J, et al. Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancer. N Engl J Med. 2007;357:2666-2676.
    • (2007) N Engl J Med , vol.357 , pp. 2666-2676
    • Miller, K.1    Wang, M.2    Gralow, J.3
  • 41
    • 0042343801 scopus 로고    scopus 로고
    • A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer
    • Yang JC, Haworth L, Sherry RM, et al. A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer. N Engl J Med. 2003;349:427-434.
    • (2003) N Engl J Med , vol.349 , pp. 427-434
    • Yang, J.C.1    Haworth, L.2    Sherry, R.M.3
  • 42
    • 77955565256 scopus 로고    scopus 로고
    • VdBM, Reardon DA, et al Proposal for updated response criteria in malignant gliomas [abstract]
    • Wen PY, Macdonald D vdBM, Reardon DA, et al Proposal for updated response criteria in malignant gliomas [abstract]. Neurooncology. 2009;11:622-623
    • (2009) Neurooncology , vol.11 , pp. 622-623
    • Wen, P.Y.1    Macdonald, D.2
  • 43
    • 59949083263 scopus 로고    scopus 로고
    • Phase II trial of single-agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma
    • Kreisl TN, Kim L, Moore K, et al. Phase II trial of single-agent bevacizumab followed by bevacizumab plus irinotecan at tumor progression in recurrent glioblastoma. J Clin Oncol. 2009;27:740-745.
    • (2009) J Clin Oncol , vol.27 , pp. 740-745
    • Kreisl, T.N.1    Kim, L.2    Moore, K.3
  • 44
    • 70350461699 scopus 로고    scopus 로고
    • Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma
    • Friedman HS, Prados MD, Wen PY, et al. Bevacizumab alone and in combination with irinotecan in recurrent glioblastoma. J Clin Oncol. 2009;27:4733-4740.
    • (2009) J Clin Oncol , vol.27 , pp. 4733-4740
    • Friedman, H.S.1    Prados, M.D.2    Wen, P.Y.3
  • 45
    • 34047238978 scopus 로고    scopus 로고
    • The relationship between six-month progression-free survival and 12-month overall survival end points for phase II trials in patients with glioblastoma multiforme
    • Ballman KV, Buckner JC, Brown PD, et al. The relationship between six-month progression-free survival and 12-month overall survival end points for phase II trials in patients with glioblastoma multiforme. Neuro Oncol. 2007;9:29-38.
    • (2007) Neuro Oncol , vol.9 , pp. 29-38
    • Ballman, K.V.1    Buckner, J.C.2    Brown, P.D.3
  • 46
    • 0032767387 scopus 로고    scopus 로고
    • Outcomes and prognostic factors in recurrent glioma patients enrolled onto phase II clinical trials
    • Wong ET, Hess KR, Gleason MJ, et al. Outcomes and prognostic factors in recurrent glioma patients enrolled onto phase II clinical trials. J Clin Oncol. 1999;17:2572-2578.
    • (1999) J Clin Oncol , vol.17 , pp. 2572-2578
    • Wong, E.T.1    Hess, K.R.2    Gleason, M.J.3
  • 47
    • 0032945307 scopus 로고    scopus 로고
    • Irinotecan therapy in adults with recurrent or progressive malignant glioma
    • Friedman HS, Petros WP, Friedman AH, et al. Irinotecan therapy in adults with recurrent or progressive malignant glioma. J Clin Oncol. 1999;17:1516-1525.
    • (1999) J Clin Oncol , vol.17 , pp. 1516-1525
    • Friedman, H.S.1    Petros, W.P.2    Friedman, A.H.3
  • 48
    • 33744477354 scopus 로고    scopus 로고
    • A phase 2 trial of irinotecan (CPT-11) in patients with recurrent malignant glioma: A North American Brain Tumor Consortium study
    • Prados MD, Lamborn K, Yung WK, et al. A phase 2 trial of irinotecan (CPT-11) in patients with recurrent malignant glioma: a North American Brain Tumor Consortium study. Neuro Oncol. 2006;8:189-193.
    • (2006) Neuro Oncol , vol.8 , pp. 189-193
    • Prados, M.D.1    Lamborn, K.2    Yung, W.K.3
  • 49
    • 0037403422 scopus 로고    scopus 로고
    • Two studies evaluating irinotecan treatment for recurrent malignant glioma using an every-3-week regimen
    • Cloughesy TF, Filka E, Kuhn J, et al. Two studies evaluating irinotecan treatment for recurrent malignant glioma using an every-3-week regimen. Cancer. 2003;97:2381-2386.
    • (2003) Cancer , vol.97 , pp. 2381-2386
    • Cloughesy, T.F.1    Filka, E.2    Kuhn, J.3
  • 50
    • 0038157018 scopus 로고    scopus 로고
    • Multicentre phase II study and pharmacokinetic analysis of irinotecan in chemotherapy-naive patients with glioblastoma
    • Raymond E, Fabbro M, Boige V, et al. Multicentre phase II study and pharmacokinetic analysis of irinotecan in chemotherapy-naive patients with glioblastoma. Ann Oncol. 2003;14:603-614.
    • (2003) Ann Oncol , vol.14 , pp. 603-614
    • Raymond, E.1    Fabbro, M.2    Boige, V.3
  • 51
    • 77955586478 scopus 로고    scopus 로고
    • Updated results of phase II trial of bevacizumab in combination with temozolomide and regional radiation therapy for up-front treatment of patients with newly-diagnosed glioblastoma Society of Neuro-Onocology Meeting 2009 Oct
    • Lai A, et al. Updated results of phase II trial of bevacizumab in combination with temozolomide and regional radiation therapy for up-front treatment of patients with newly-diagnosed glioblastoma Society of Neuro-Onocology Meeting 2009 Oct.
    • Lai, A.1
  • 53
    • 0030279844 scopus 로고    scopus 로고
    • Glioblastoma multiforme: Radiologic-pathologic correlation
    • quiz 62-63
    • Rees JH, Smirniotopoulos JG, Jones RV, Wong K. Glioblastoma multiforme: radiologic-pathologic correlation. Radiographics. 1996;16:1413-1438; quiz 62-63.
    • (1996) Radiographics , vol.16 , pp. 1413-1438
    • Rees, J.H.1    Smirniotopoulos, J.G.2    Jones, R.V.3    Wong, K.4
  • 54
    • 33646675851 scopus 로고    scopus 로고
    • MRI in patients with high-grade gliomas treated with bevacizumab and chemotherapy
    • Pope WB, Lai A, Nghiemphu P, Mischel P, Cloughesy TF. MRI in patients with high-grade gliomas treated with bevacizumab and chemotherapy. Neurology. 2006;66:1258-1260.
    • (2006) Neurology , vol.66 , pp. 1258-1260
    • Pope, W.B.1    Lai, A.2    Nghiemphu, P.3    Mischel, P.4    Cloughesy, T.F.5
  • 55
    • 44649095050 scopus 로고    scopus 로고
    • Time course of imaging changes of GBM during extended bevacizumab treatment
    • Ananthnarayan S, Bahng J, Roring J, et al. Time course of imaging changes of GBM during extended bevacizumab treatment. J Neurooncol. 2008;88:339-347.
    • (2008) J Neurooncol , vol.88 , pp. 339-347
    • Ananthnarayan, S.1    Bahng, J.2    Roring, J.3
  • 56
    • 33947191055 scopus 로고    scopus 로고
    • Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma
    • Vredenburgh JJ, Desjardins A, Herndon JE 2nd, et al. Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma. Clin Cancer Res. 2007;13:1253-1259.
    • (2007) Clin Cancer Res , vol.13 , pp. 1253-1259
    • Vredenburgh, J.J.1    Desjardins, A.2    Herndon II, J.E.3
  • 58
    • 67649819585 scopus 로고    scopus 로고
    • Bevacizumab and paclitaxel for breast cancer patients with central nervous system metastases: A case series
    • Labidi SI, Bachelot T, Ray-Coquard I, et al. Bevacizumab and paclitaxel for breast cancer patients with central nervous system metastases: a case series. Clin Breast Cancer. 2009;9:118-121.
    • (2009) Clin Breast Cancer , vol.9 , pp. 118-121
    • Labidi, S.I.1    Bachelot, T.2    Ray-Coquard, I.3
  • 59
    • 56949104849 scopus 로고    scopus 로고
    • The effect of bevacizumab (Avastin) on neuroimaging of brain metastases
    • Mathews MS, Linskey ME, Hasso AN, Fruehauf JP. The effect of bevacizumab (Avastin) on neuroimaging of brain metastases. Surg Neurol. 2008;70:649-653.
    • (2008) Surg Neurol , vol.70 , pp. 649-653
    • Mathews, M.S.1    Linskey, M.E.2    Hasso, A.N.3    Fruehauf, J.P.4
  • 61
    • 0035884609 scopus 로고    scopus 로고
    • Inhibition of glioma angiogenesis and growth in vivo by systemic treatment with a monoclonal antibody against vascular endothelial growth factor receptor-2
    • Kunkel P, Ulbricht U, Bohlen P, et al. Inhibition of glioma angiogenesis and growth in vivo by systemic treatment with a monoclonal antibody against vascular endothelial growth factor receptor-2. Cancer Res. 2001;61:6624-6628.
    • (2001) Cancer Res , vol.61 , pp. 6624-6628
    • Kunkel, P.1    Ulbricht, U.2    Bohlen, P.3
  • 62
    • 27644450912 scopus 로고    scopus 로고
    • Inhibition of glioblastoma angiogenesis and invasion by combined treatments directed against vascular endothelial growth factor receptor-2, epidermal growth factor receptor, and vascular endothelial-cadherin
    • Lamszus K, Brockmann MA, Eckerich C, et al. Inhibition of glioblastoma angiogenesis and invasion by combined treatments directed against vascular endothelial growth factor receptor-2, epidermal growth factor receptor, and vascular endothelial-cadherin. Clin Cancer Res. 2005;11:4934-4940.
    • (2005) Clin Cancer Res , vol.11 , pp. 4934-4940
    • Lamszus, K.1    Brockmann, M.A.2    Eckerich, C.3
  • 63
    • 68649120407 scopus 로고    scopus 로고
    • Recurrence pattern in glioblastoma multiforme patients treated with anti-angiogenic chemotherapy
    • Tuettenberg J, Grobholz R, Seiz M, et al. Recurrence pattern in glioblastoma multiforme patients treated with anti-angiogenic chemotherapy. J Cancer Res Clin Oncol. 2009;135:1239-1244.
    • (2009) J Cancer Res Clin Oncol , vol.135 , pp. 1239-1244
    • Tuettenberg, J.1    Grobholz, R.2    Seiz, M.3
  • 64
    • 70350142397 scopus 로고    scopus 로고
    • Patterns of relapse and prognosis after bevacizumab failure in recurrent glioblastoma
    • Iwamoto FM, Abrey LE, Beal K, et al. Patterns of relapse and prognosis after bevacizumab failure in recurrent glioblastoma. Neurology. 2009;73:1200-1206.
    • (2009) Neurology , vol.73 , pp. 1200-1206
    • Iwamoto, F.M.1    Abrey, L.E.2    Beal, K.3
  • 65
    • 41649112610 scopus 로고    scopus 로고
    • Bevacizumab for recurrent malignant gliomas: Efficacy, toxicity, and patterns of recurrence
    • Norden AD, Young GS, Setayesh K, et al. Bevacizumab for recurrent malignant gliomas: efficacy, toxicity, and patterns of recurrence. Neurology. 2008;70:779-787.
    • (2008) Neurology , vol.70 , pp. 779-787
    • Norden, A.D.1    Young, G.S.2    Setayesh, K.3
  • 66
    • 77950959783 scopus 로고    scopus 로고
    • Patterns of progression in patients with glioblastoma at first or second relapse treated wtih bevacizumab alone or in combination with irinotecan in the BRAIN study
    • Pope WB, Das Q, Hambleton A, et al. Patterns of progression in patients with glioblastoma at first or second relapse treated wtih bevacizumab alone or in combination with irinotecan in the BRAIN study. Neuro Oncol. 2009;11:563-699.
    • (2009) Neuro Oncol , vol.11 , pp. 563-699
    • Pope, W.B.1    Das, Q.2    Hambleton, A.3
  • 68
    • 63449141069 scopus 로고    scopus 로고
    • Early clinical and neuroradiological worsening after radiotherapy and concomitant temozolomide in patients with glioblastoma: Tumour progression or radionecrosis?
    • Peca C, Pacelli R, Elefante A, et al. Early clinical and neuroradiological worsening after radiotherapy and concomitant temozolomide in patients with glioblastoma: tumour progression or radionecrosis? Clin Neurol Neurosurg. 2009;111:331-334.
    • (2009) Clin Neurol Neurosurg , vol.111 , pp. 331-334
    • Peca, C.1    Pacelli, R.2    Elefante, A.3
  • 69
    • 0036210301 scopus 로고    scopus 로고
    • Intracranial mass lesions: Dynamic contrast-enhanced susceptibility-weighted echo-planar perfusion MR imaging
    • Cha S, Knopp EA, Johnson G, Wetzel SG, Litt AW, Zagzag D. Intracranial mass lesions: dynamic contrast-enhanced susceptibility-weighted echo-planar perfusion MR imaging. Radiology. 2002;223:11-29.
    • (2002) Radiology , vol.223 , pp. 11-29
    • Cha, S.1    Knopp, E.A.2    Johnson, G.3    Wetzel, S.G.4    Litt, A.W.5    Zagzag, D.6
  • 70
    • 1242271955 scopus 로고    scopus 로고
    • Diffusion-weighted imaging in the follow-up of treated high-grade gliomas: Tumor recurrence versus radiation injury
    • Hein PA, Eskey CJ, Dunn JF, Hug EB. Diffusion-weighted imaging in the follow-up of treated high-grade gliomas: tumor recurrence versus radiation injury. AJNR Am J Neuroradiol. 2004;25:201-209.
    • (2004) AJNR Am J Neuroradiol , vol.25 , pp. 201-209
    • Hein, P.A.1    Eskey, C.J.2    Dunn, J.F.3    Hug, E.B.4
  • 71
    • 13944253196 scopus 로고    scopus 로고
    • Tl-201 SPECT and F-18 FDG PET for assessment of glioma recurrence versus radiation necrosis
    • Siepmann DB, Siegel A, Lewis PJ. Tl-201 SPECT and F-18 FDG PET for assessment of glioma recurrence versus radiation necrosis. Clin Nucl Med. 2005;30:199-200.
    • (2005) Clin Nucl Med , vol.30 , pp. 199-200
    • Siepmann, D.B.1    Siegel, A.2    Lewis, P.J.3
  • 72
    • 67650075305 scopus 로고    scopus 로고
    • Recurrent glioblastoma multiforme: ADC histogram analysis predicts response to bevacizumab treatment
    • Pope WB, Kim HJ, Huo J, et al. Recurrent glioblastoma multiforme: ADC histogram analysis predicts response to bevacizumab treatment. Radiology. 2009;252:182-189.
    • (2009) Radiology , vol.252 , pp. 182-189
    • Pope, W.B.1    Kim, H.J.2    Huo, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.