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Volumn 18, Issue 4, 2010, Pages 494-497

MELAS with recurrent complex partial seizures, nonconvulsive status epilepticus, psychosis, and behavioral disturbances: Case analysis with literature review

Author keywords

Aggression; Coenzyme Q10; Complex partial seizures; Education; Levocarnitine; Mitochondrial encephalopathy; Mitochondrial encephalopathy, lactic acidosis, and strokelike episodes (MELAS); Nonconvulsive status epilepticus; Oxidative stress; Paranoid delusions; Psychosis, hallucinations; Treatment; Valproate; Video EEG monitoring; Vitamin E

Indexed keywords

ACETYLSALICYLIC ACID; ALPHA TOCOPHEROL; ANTICONVULSIVE AGENT; ATORVASTATIN; CARNITINE; DOXYCYCLINE; GABAPENTIN; INSULIN; INSULIN LISPRO; ISOPHANE INSULIN; LORAZEPAM; MULTIVITAMIN; OLANZAPINE; PHENYTOIN; UBIDECARENONE; VALPROATE SEMISODIUM; VALPROIC ACID;

EID: 77955576599     PISSN: 15255050     EISSN: 15255069     Source Type: Journal    
DOI: 10.1016/j.yebeh.2010.05.020     Document Type: Article
Times cited : (47)

References (46)
  • 1
    • 54949142139 scopus 로고    scopus 로고
    • Mitochondrial encephalopathy, lactic acidosis, and strokelike episodes: basic concepts, clinical phenotypes, and therapeutic management of MELAS syndrome
    • Sproule D.M., Kaufmann P. Mitochondrial encephalopathy, lactic acidosis, and strokelike episodes: basic concepts, clinical phenotypes, and therapeutic management of MELAS syndrome. Ann NY Acad Sci 2008, 1142:133-158.
    • (2008) Ann NY Acad Sci , vol.1142 , pp. 133-158
    • Sproule, D.M.1    Kaufmann, P.2
  • 2
    • 34948867248 scopus 로고    scopus 로고
    • Prevalence, segregation, and phenotype of the mitochondrial DNA 3243A>G mutation in children
    • Uusimaa J., Moilanen J.S., Vainionpaa L., et al. Prevalence, segregation, and phenotype of the mitochondrial DNA 3243A>G mutation in children. Ann Neurol 2007, 62:278-287.
    • (2007) Ann Neurol , vol.62 , pp. 278-287
    • Uusimaa, J.1    Moilanen, J.S.2    Vainionpaa, L.3
  • 3
    • 33947278405 scopus 로고    scopus 로고
    • Population prevalence of the MELAS A3243G mutation
    • Manwaring N., Jones M.M., Wang J.J., et al. Population prevalence of the MELAS A3243G mutation. Mitochondrion 2007, 7:230-233.
    • (2007) Mitochondrion , vol.7 , pp. 230-233
    • Manwaring, N.1    Jones, M.M.2    Wang, J.J.3
  • 4
    • 45849084212 scopus 로고    scopus 로고
    • Multiple neurologic, psychiatric and endocrine complaints in a young woman: a case discussion and review of the clinical features and management of mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke
    • Bhuvaneswar C.G., Goetz J.L., Stern T.A. Multiple neurologic, psychiatric and endocrine complaints in a young woman: a case discussion and review of the clinical features and management of mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke. Prim Care Companion J Clin Psychiatry 2008, 10:237-244.
    • (2008) Prim Care Companion J Clin Psychiatry , vol.10 , pp. 237-244
    • Bhuvaneswar, C.G.1    Goetz, J.L.2    Stern, T.A.3
  • 5
    • 33644521249 scopus 로고    scopus 로고
    • An infant with a mitochondrial A3243G mutation demonstrating the MELAS phenotype
    • Kanaumi T., Hirose S., Goto Y., Naitou E., Mitsudome A. An infant with a mitochondrial A3243G mutation demonstrating the MELAS phenotype. Pediatr Neurol 2005, 34:235-238.
    • (2005) Pediatr Neurol , vol.34 , pp. 235-238
    • Kanaumi, T.1    Hirose, S.2    Goto, Y.3    Naitou, E.4    Mitsudome, A.5
  • 6
    • 0035347538 scopus 로고    scopus 로고
    • An 80-year-old mitochondrial disease patient with A3243G tRNA(Leu(UUR)) gene presenting with cardiac dysfunction as the main symptom
    • Higashikata T., Koyama J., Shimada H., Yazaki M., Owa M., Ikeda S. An 80-year-old mitochondrial disease patient with A3243G tRNA(Leu(UUR)) gene presenting with cardiac dysfunction as the main symptom. Intern Med 2001, 40:405-408.
    • (2001) Intern Med , vol.40 , pp. 405-408
    • Higashikata, T.1    Koyama, J.2    Shimada, H.3    Yazaki, M.4    Owa, M.5    Ikeda, S.6
  • 7
    • 33744823262 scopus 로고    scopus 로고
    • The mitochondrial myopathy, encephalopathy, lactic acidosis with stroke-like episodes (MELAS) syndrome: a review of treatment options
    • Scaglia F., Northrop J.L. The mitochondrial myopathy, encephalopathy, lactic acidosis with stroke-like episodes (MELAS) syndrome: a review of treatment options. CNS Drugs 2006, 20:443-464.
    • (2006) CNS Drugs , vol.20 , pp. 443-464
    • Scaglia, F.1    Northrop, J.L.2
  • 8
    • 48349112611 scopus 로고    scopus 로고
    • Cognitive decline as a manifestation of mitochondrial disorders (mitochondrial dementia)
    • Finsterer J. Cognitive decline as a manifestation of mitochondrial disorders (mitochondrial dementia). J Neurol Sci 2008, 272:20-33.
    • (2008) J Neurol Sci , vol.272 , pp. 20-33
    • Finsterer, J.1
  • 9
    • 0033546906 scopus 로고    scopus 로고
    • Age and cause of death in mitochondrial diseases
    • Klopstock T., Jaksch M., Gasser T. Age and cause of death in mitochondrial diseases. Neurology 1999, 53:855-857.
    • (1999) Neurology , vol.53 , pp. 855-857
    • Klopstock, T.1    Jaksch, M.2    Gasser, T.3
  • 11
    • 29544442825 scopus 로고    scopus 로고
    • Review of the literature on mental disorders in adult patients with mitochondrial diseases
    • Fattal O., Budur K., Vaughan A.J., Franco K. Review of the literature on mental disorders in adult patients with mitochondrial diseases. Psychosomatics 2006, 47:1-7.
    • (2006) Psychosomatics , vol.47 , pp. 1-7
    • Fattal, O.1    Budur, K.2    Vaughan, A.J.3    Franco, K.4
  • 12
    • 0029011473 scopus 로고
    • MELAS syndrome: peripheral neuropathy and cytochrome C-oxidase deficiency: a case report and review of the literature
    • Barak Y., Arnon S., Wolach B., et al. MELAS syndrome: peripheral neuropathy and cytochrome C-oxidase deficiency: a case report and review of the literature. Isr J Med Sci 1995, 31:224-229.
    • (1995) Isr J Med Sci , vol.31 , pp. 224-229
    • Barak, Y.1    Arnon, S.2    Wolach, B.3
  • 13
    • 34250209147 scopus 로고    scopus 로고
    • The neuropsychological deficits of MELAS: evidence of global impairment
    • Neargarder S.A., Murtagh M.P., Wong B., Hill E.K. The neuropsychological deficits of MELAS: evidence of global impairment. Cogn Behav Neurol 2007, 20:83-92.
    • (2007) Cogn Behav Neurol , vol.20 , pp. 83-92
    • Neargarder, S.A.1    Murtagh, M.P.2    Wong, B.3    Hill, E.K.4
  • 14
    • 33644539194 scopus 로고    scopus 로고
    • Characteristics of status epilepticus in MELAS: analysis of four cases
    • Ribacoba R., Salas-Puig J., Gonzalez C., Astudillo A. Characteristics of status epilepticus in MELAS: analysis of four cases. Neurologia 2006, 21:1-11.
    • (2006) Neurologia , vol.21 , pp. 1-11
    • Ribacoba, R.1    Salas-Puig, J.2    Gonzalez, C.3    Astudillo, A.4
  • 17
    • 33845993258 scopus 로고    scopus 로고
    • Psychiatric manifestations of nonconvulsive status epilepticus
    • Riggio S. Psychiatric manifestations of nonconvulsive status epilepticus. Mt Sinai J Med 2006, 73:960-969.
    • (2006) Mt Sinai J Med , vol.73 , pp. 960-969
    • Riggio, S.1
  • 18
    • 0344420421 scopus 로고    scopus 로고
    • Aggressive confusional state as a clinical manifestation of status epilepticus in MELAS
    • Feddersen B., Bender A., Arnold S., Klopstock T., Noachtar S. Aggressive confusional state as a clinical manifestation of status epilepticus in MELAS. Neurology 2003, 61:1149-1150.
    • (2003) Neurology , vol.61 , pp. 1149-1150
    • Feddersen, B.1    Bender, A.2    Arnold, S.3    Klopstock, T.4    Noachtar, S.5
  • 20
    • 0345411594 scopus 로고    scopus 로고
    • Fatal status epilepticus associated with olanzapine therapy
    • Wyderski R.J., Starrett W.G., Abou-Saif A. Fatal status epilepticus associated with olanzapine therapy. Ann Pharmacother 1999, 33:787-789.
    • (1999) Ann Pharmacother , vol.33 , pp. 787-789
    • Wyderski, R.J.1    Starrett, W.G.2    Abou-Saif, A.3
  • 21
    • 0035185739 scopus 로고    scopus 로고
    • Lowered seizure threshold on olanzapine
    • Woolley J., Smith S. Lowered seizure threshold on olanzapine. Br J Psychiatry 2001, 178:85-86.
    • (2001) Br J Psychiatry , vol.178 , pp. 85-86
    • Woolley, J.1    Smith, S.2
  • 23
    • 34548846929 scopus 로고    scopus 로고
    • Seizure incidence in psychopharmacological clinical trials: an analysis of Food and Drug Administration (FDA) summary basis of approval reports
    • Alper K., Schwartz K.A., Kolts R.L., Khan A. Seizure incidence in psychopharmacological clinical trials: an analysis of Food and Drug Administration (FDA) summary basis of approval reports. Biol Psychiatry 2007, 62:345-354.
    • (2007) Biol Psychiatry , vol.62 , pp. 345-354
    • Alper, K.1    Schwartz, K.A.2    Kolts, R.L.3    Khan, A.4
  • 24
    • 33646079164 scopus 로고    scopus 로고
    • "Erratic" complex partial status epilepticus as a presenting feature of MELAS
    • Corda D., Rosati G., Deiana G.A., Sechi G. "Erratic" complex partial status epilepticus as a presenting feature of MELAS. Epilepsy Behav 2006, 8:655-658.
    • (2006) Epilepsy Behav , vol.8 , pp. 655-658
    • Corda, D.1    Rosati, G.2    Deiana, G.A.3    Sechi, G.4
  • 25
    • 0019883418 scopus 로고
    • Special report: the nature of aggression during epileptic seizures
    • Delgado-Escueta A.V., Mattson R.H., King L., et al. Special report: the nature of aggression during epileptic seizures. N Engl J Med 1981, 305:711-716.
    • (1981) N Engl J Med , vol.305 , pp. 711-716
    • Delgado-Escueta, A.V.1    Mattson, R.H.2    King, L.3
  • 26
    • 3042727057 scopus 로고    scopus 로고
    • Recognition of the various expressions of anxiety, psychosis, and aggression in epilepsy
    • Kanner A.M. Recognition of the various expressions of anxiety, psychosis, and aggression in epilepsy. Epilepsia 2004, 45(Suppl. 2):22-27.
    • (2004) Epilepsia , vol.45 , Issue.SUPPL. 2 , pp. 22-27
    • Kanner, A.M.1
  • 27
    • 46849093011 scopus 로고    scopus 로고
    • Importance of early recognition and treatment of generalized convulsive status epilepticus
    • Treiman D.M. Importance of early recognition and treatment of generalized convulsive status epilepticus. Lancet Neurol 2008, 7:667-668.
    • (2008) Lancet Neurol , vol.7 , pp. 667-668
    • Treiman, D.M.1
  • 29
    • 27944500207 scopus 로고    scopus 로고
    • The clinical features, diagnosis, and prognosis of nonconvulsive status epilepticus
    • Kaplan P.W. The clinical features, diagnosis, and prognosis of nonconvulsive status epilepticus. Neurologist 2005, 11:348-361.
    • (2005) Neurologist , vol.11 , pp. 348-361
    • Kaplan, P.W.1
  • 30
    • 34548508914 scopus 로고    scopus 로고
    • Diagnosis and management of nonconvulsive status epilepticus in children
    • Korff C.M., Nordli D.R. Diagnosis and management of nonconvulsive status epilepticus in children. Nat Clin Pract Neurol 2007, 3:505-516.
    • (2007) Nat Clin Pract Neurol , vol.3 , pp. 505-516
    • Korff, C.M.1    Nordli, D.R.2
  • 32
    • 35748984402 scopus 로고    scopus 로고
    • The role of mitochondria in status epilepticus
    • Cock H. The role of mitochondria in status epilepticus. Epilepsia 2007, 48(Suppl. 8):24-27.
    • (2007) Epilepsia , vol.48 , Issue.SUPPL. 8 , pp. 24-27
    • Cock, H.1
  • 33
    • 58549108191 scopus 로고    scopus 로고
    • MELAS syndrome, diabetes, and thyroid disease: the role of mitochondrial oxidative stress
    • Tan T.M., Caputo C., Medici F., et al. MELAS syndrome, diabetes, and thyroid disease: the role of mitochondrial oxidative stress. Clin Endocrinol (Oxf) 2009, 70:340-341.
    • (2009) Clin Endocrinol (Oxf) , vol.70 , pp. 340-341
    • Tan, T.M.1    Caputo, C.2    Medici, F.3
  • 34
    • 29744462142 scopus 로고    scopus 로고
    • L-Carnitine and neuroprotection in the animal model of mitochondrial dysfunction
    • Binienda Z., Przybyia-Zawisiak B., Virmani A., Schmued L. L-Carnitine and neuroprotection in the animal model of mitochondrial dysfunction. Ann NY Acad Sci 2005, 1053:174-182.
    • (2005) Ann NY Acad Sci , vol.1053 , pp. 174-182
    • Binienda, Z.1    Przybyia-Zawisiak, B.2    Virmani, A.3    Schmued, L.4
  • 35
    • 0036900547 scopus 로고    scopus 로고
    • Free radical-mediated cell damage after experimental status epilepticus in hippocampal slice cultures
    • Kovacs R., Schuchmann S., Gabriel S., Kann O., Kardos J., Heinemann U. Free radical-mediated cell damage after experimental status epilepticus in hippocampal slice cultures. J Neurophysiol 2002, 88:2909-2918.
    • (2002) J Neurophysiol , vol.88 , pp. 2909-2918
    • Kovacs, R.1    Schuchmann, S.2    Gabriel, S.3    Kann, O.4    Kardos, J.5    Heinemann, U.6
  • 36
    • 46149099325 scopus 로고    scopus 로고
    • Pharmacologic suppression of oxidative damage and dendritic degeneration following kainic acid-induced excitotoxicity in mouse cerebrum
    • Zaja-Milatovic S., Gupta R.C., Aschner M., Montine T.J., Milatovic D. Pharmacologic suppression of oxidative damage and dendritic degeneration following kainic acid-induced excitotoxicity in mouse cerebrum. Neurotoxicology 2008, 29:621-627.
    • (2008) Neurotoxicology , vol.29 , pp. 621-627
    • Zaja-Milatovic, S.1    Gupta, R.C.2    Aschner, M.3    Montine, T.J.4    Milatovic, D.5
  • 37
    • 41049096163 scopus 로고    scopus 로고
    • Vitamin E and L-carnitine, separately or in combination, in the prevention of radiation-induced brain and retinal damages
    • Sezen O., Ertekin M.V., Demircan B., et al. Vitamin E and L-carnitine, separately or in combination, in the prevention of radiation-induced brain and retinal damages. Neurosurg Rev 2008, 31:205-213.
    • (2008) Neurosurg Rev , vol.31 , pp. 205-213
    • Sezen, O.1    Ertekin, M.V.2    Demircan, B.3
  • 38
    • 4344684797 scopus 로고    scopus 로고
    • Coenzyme Q 10 improves lactic acidosis, strokelike episodes, and epilepsy in a patient with MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes)
    • Berbel-Garcia A., Barbera-Farre J.R., Etessam J.P., et al. Coenzyme Q 10 improves lactic acidosis, strokelike episodes, and epilepsy in a patient with MELAS (mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes). Clin Neuropharmacol 2004, 27:187-191.
    • (2004) Clin Neuropharmacol , vol.27 , pp. 187-191
    • Berbel-Garcia, A.1    Barbera-Farre, J.R.2    Etessam, J.P.3
  • 40
    • 0032541616 scopus 로고    scopus 로고
    • A comparison of four treatments for generalized convulsive status epilepticus
    • Treiman D.M., Meyers P.D., Walton N.Y., et al. A comparison of four treatments for generalized convulsive status epilepticus. N Engl J Med 1998, 339:792-798.
    • (1998) N Engl J Med , vol.339 , pp. 792-798
    • Treiman, D.M.1    Meyers, P.D.2    Walton, N.Y.3
  • 41
    • 33747070541 scopus 로고    scopus 로고
    • Sodium valproate vs phenytoin in status epilepticus: a pilot study
    • Misra U.K., Kalita J., Patel R. Sodium valproate vs phenytoin in status epilepticus: a pilot study. Neurology 2006, 67:340-342.
    • (2006) Neurology , vol.67 , pp. 340-342
    • Misra, U.K.1    Kalita, J.2    Patel, R.3
  • 42
    • 57249103572 scopus 로고    scopus 로고
    • The role of the newer antiepileptic drugs in the treatment of generalized convulsive status epilepticus
    • Wheless J.W., Treiman D.M. The role of the newer antiepileptic drugs in the treatment of generalized convulsive status epilepticus. Epilepsia 2008, 49(Suppl. 9):74-78.
    • (2008) Epilepsia , vol.49 , Issue.SUPPL. 9 , pp. 74-78
    • Wheless, J.W.1    Treiman, D.M.2
  • 43
    • 34247622195 scopus 로고    scopus 로고
    • Carnitine as an antidote for acute valproate toxicity in children
    • Russell S. Carnitine as an antidote for acute valproate toxicity in children. Curr Opin Pediatr 2007, 19:206-210.
    • (2007) Curr Opin Pediatr , vol.19 , pp. 206-210
    • Russell, S.1
  • 44
    • 0030758778 scopus 로고    scopus 로고
    • Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) triggered by valproate therapy
    • Lam C.W., Lau C.H., Williams J.C., Chan Y.W., Wong L.J. Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) triggered by valproate therapy. Eur J Pediatr 1997, 156:562-564.
    • (1997) Eur J Pediatr , vol.156 , pp. 562-564
    • Lam, C.W.1    Lau, C.H.2    Williams, J.C.3    Chan, Y.W.4    Wong, L.J.5
  • 45
    • 33847632882 scopus 로고    scopus 로고
    • Valproic acid aggravates epilepsy due to MELAS in a patient with an A3243G mutation of mitochondrial DNA
    • Lin C.M., Thajeb P. Valproic acid aggravates epilepsy due to MELAS in a patient with an A3243G mutation of mitochondrial DNA. Metab Brain Dis 2007, 22:105-109.
    • (2007) Metab Brain Dis , vol.22 , pp. 105-109
    • Lin, C.M.1    Thajeb, P.2
  • 46
    • 0344896751 scopus 로고    scopus 로고
    • Nonconvulsive status epilepticus
    • Kaplan P.W. Nonconvulsive status epilepticus. Neurology 2003, 61:1035-1036.
    • (2003) Neurology , vol.61 , pp. 1035-1036
    • Kaplan, P.W.1


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