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Volumn 302, Issue 6, 2010, Pages 419-428

Protease and pro-inflammatory cytokine concentrations are elevated in chronic compared to acute wounds and can be modulated by collagen type i in vitro

Author keywords

Acute wounds; Chronic wounds; Collagen type I; Matrix metalloproteinases; PMN elastase; Pro inflammatory cytokines

Indexed keywords

COLLAGEN TYPE 1; CYTOKINE; ELASTASE; GELATINASE A; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; PROTEINASE;

EID: 77955552322     PISSN: 03403696     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00403-009-1011-1     Document Type: Article
Times cited : (88)

References (48)
  • 2
    • 0033396265 scopus 로고    scopus 로고
    • Leukocyte proteinases in wound healing: Roles in physiologic and pathologic processes
    • DOI 10.1046/j.1524-475X.1999.00410.x
    • B Barrick EJ Campbell CA Owen 1999 Leukocyte proteinases in wound healing: roles in physiologic and pathologic processes Wound Rep Reg 7 410 422 10.1046/j.1524-475X.1999.00410.x 1:STN:280:DC%2BD3c%2FpvVyrtA%3D%3D (Pubitemid 30027563)
    • (1999) Wound Repair and Regeneration , vol.7 , Issue.6 , pp. 410-422
    • Barrick, B.1    Campbell, E.J.2    Owen, C.A.3
  • 3
    • 22844434968 scopus 로고    scopus 로고
    • Normal cutaneous wound healing: Clinical correlation with cellular and molecular events
    • 1:CAS:528:DC%2BD2sXit1WlsQ%3D%3D 15996419
    • CL Baum CJ Arpey 2005 Normal cutaneous wound healing: clinical correlation with cellular and molecular events Dermatol Surg 31 674 686 1:CAS:528:DC%2BD2sXit1WlsQ%3D%3D 15996419
    • (2005) Dermatol Surg , vol.31 , pp. 674-686
    • Baum, C.L.1    Arpey, C.J.2
  • 4
    • 0345014915 scopus 로고    scopus 로고
    • Excessive neutrophils characterize chronic pressure ulcers
    • DOI 10.1046/j.1524-475X.2003.11617.x
    • RF Diegelmann 2003 Excessive neutrophils characterize chronic pressure ulcers Wound Rep Reg 11 490 495 10.1046/j.1524-475X.2003.11617.x (Pubitemid 37467733)
    • (2003) Wound Repair and Regeneration , vol.11 , Issue.6 , pp. 490-495
    • Diegelmann, R.F.1
  • 5
    • 0025777448 scopus 로고
    • Interleukin-1 and interleukin-1 antagonism
    • 1:CAS:528:DyaK3MXktVKmsLY%3D 1826616
    • CA Dinarello 1991 Interleukin-1 and interleukin-1 antagonism Blood 77 1627 1652 1:CAS:528:DyaK3MXktVKmsLY%3D 1826616
    • (1991) Blood , vol.77 , pp. 1627-1652
    • Dinarello, C.A.1
  • 6
    • 31744443648 scopus 로고    scopus 로고
    • Wann ist eine wunde chronisch?
    • DOI 10.1007/s00105-005-1048-9
    • J Dissemond 2006 Wann ist eine Wunde chronisch? Hautarzt 57 55 10.1007/s00105-005-1048-9 1:STN:280:DC%2BD28%2FlsFSgtQ%3D%3D 16240151 (Pubitemid 43175705)
    • (2006) Hautarzt , vol.57 , Issue.1 , pp. 55
    • Dissemond, J.1
  • 7
    • 4444299786 scopus 로고    scopus 로고
    • The role of collagen in thrombosis and hemostasis
    • DOI 10.1111/j.1538-7836.2004.00665.x
    • RW Farndale JJ Sixma MJ Barnes PG de Groot 2004 The role of collagen in thrombosis and hemostasis J Thromb Haemost 2 561 573 10.1111/j.1538-7836.2004. 00665.x 1:CAS:528:DC%2BD2cXjslWntLs%3D 15102010 (Pubitemid 40185679)
    • (2004) Journal of Thrombosis and Haemostasis , vol.2 , Issue.4 , pp. 561-573
    • Farndale, R.W.1    Sixma, J.J.2    Barnes, M.J.3    De Groot, P.G.4
  • 8
    • 0031960548 scopus 로고    scopus 로고
    • Collagen - Biomaterial for drug delivery
    • DOI 10.1016/S0939-6411(98)00017-4, PII S0939641198000174
    • W Friess 1998 Collagen-biomaterial for drug delivery Eur J Pharm Biopharm 45 113 136 10.1016/S0939-6411(98)00017-4 1:CAS:528:DyaK1cXisVOitbc%3D 9704909 (Pubitemid 28167739)
    • (1998) European Journal of Pharmaceutics and Biopharmaceutics , vol.45 , Issue.2 , pp. 113-136
    • Friess, W.1
  • 9
    • 0033664369 scopus 로고    scopus 로고
    • Impaired cutaneous wound healing in interleukin-6-deficient and immunosuppressed mice
    • 10.1096/fj.00-0073com 1:CAS:528:DC%2BD3MXht1SntLo%3D 11099471
    • RM Gallucci PP Simeonova JM Metheson C Kommineni JL Guriel T Sugawara, et al. 2000 Impaired cutaneous wound healing in interleukin-6-deficient and immunosuppressed mice FASEB J 14 2525 2531 10.1096/fj.00-0073com 1:CAS:528:DC%2BD3MXht1SntLo%3D 11099471
    • (2000) FASEB J , vol.14 , pp. 2525-2531
    • Gallucci, R.M.1    Simeonova, P.P.2    Metheson, J.M.3    Kommineni, C.4    Guriel, J.L.5    Sugawara, T.6
  • 10
    • 0035075706 scopus 로고    scopus 로고
    • Chemokines in cutaneous wound healing
    • 1:CAS:528:DC%2BD3MXivVaguro%3D 11310836
    • R Gillitzer M Goebeler 2001 Chemokines in cutaneous wound healing J Leukoc Biol 69 513 521 1:CAS:528:DC%2BD3MXivVaguro%3D 11310836
    • (2001) J Leukoc Biol , vol.69 , pp. 513-521
    • Gillitzer, R.1    Goebeler, M.2
  • 11
    • 0027315821 scopus 로고
    • Fibroblasts increase adhesion to neutrophils after stimulation with phorbol ester and cytokines
    • DOI 10.1006/cimm.1993.1148
    • AL Giuliani S Spisani T Cavalletti E Reali L Melchiorri L Ferrari, et al. 1993 Fibroblasts increase adhesion to neutrophils after stimulation with phorbol ester and cytokines Cell Immunol 149 208 222 10.1006/cimm.1993.1148 1:CAS:528:DyaK3sXksVOiurg%3D 8099851 (Pubitemid 23196016)
    • (1993) Cellular Immunology , vol.149 , Issue.1 , pp. 208-222
    • Giuliani, A.L.1    Spisani, S.2    Cavalletti, T.3    Reali, E.4    Melchiorri, L.5    Ferrari, L.6    Lanza, F.7    Traniello, S.8
  • 12
    • 33644651282 scopus 로고    scopus 로고
    • Severely impaired insulin signaling in chronic wounds of diabetic ob/ob mice: A potential role of tumor necrosis factor-α
    • DOI 10.2353/ajpath.2006.050293
    • I Goren E Müller F Pfeilschnifter S Frank 2006 Severely impaired insulin signaling in chronic wounds of diabetic ob/ob mice-a potential role of tumor necrosis factor-α Am J Pathol 168 765 777 10.2353/ajpath.2006.050293 1:CAS:528:DC%2BD28XislGgtLs%3D 16507892 (Pubitemid 43327729)
    • (2006) American Journal of Pathology , vol.168 , Issue.3 , pp. 765-777
    • Goren, I.1    Muller, E.2    Pfeilschifter, J.3    Frank, S.4
  • 13
    • 0026605281 scopus 로고
    • Degradation of fibronectin and vitronectin in chronic wound fluid: Analysis by cell blotting, immunoblotting, and cell adhesion assays
    • 10.1111/1523-1747.ep12499839
    • F Grinnel CH Ho A Wysocki 1992 Degradation of fibronectin and vitronectin in chronic wound fluid: analysis by cell blotting, immunoblotting, and cell adhesion assays J Invest Dermatol 98 410 416 10.1111/1523-1747.ep12499839
    • (1992) J Invest Dermatol , vol.98 , pp. 410-416
    • Grinnel, F.1    Ho, C.H.2    Wysocki, A.3
  • 14
    • 33746441058 scopus 로고    scopus 로고
    • Interleukin-6 promotes human epidermal keratinocyte proliferation and keratin cytoskeleton reorganization in culture
    • DOI 10.1007/s00441-006-0173-9
    • M Haernandez-Quintero AG Robles W Kuri-Harcuch F Castro-Munozledo 2006 Interleukin-6 promotes human epidermal keratinocyte proliferation and keratin cytoskeleton reorganization in culture Cell Tissue Res 325 77 90 10.1007/s00441-006-0173-9 (Pubitemid 44124300)
    • (2006) Cell and Tissue Research , vol.325 , Issue.1 , pp. 77-90
    • Hernandez-Quintero, M.1    Kuri-Harcuch, W.2    Gonzalez Robles, A.3    Castro-Munozledo, F.4
  • 16
    • 0035156633 scopus 로고    scopus 로고
    • TNF-α stimulates activation of pro-MMP2 in human skin through NF-κB mediated induction of MT1-MMP
    • 1:CAS:528:DC%2BD3MXhtVSgsL0%3D 11112697
    • Y-P Han T-L Tuan H Wu M Hughes WL Garner 2001 TNF-α stimulates activation of pro-MMP2 in human skin through NF-κB mediated induction of MT1-MMP J Cell Sci 114 131 139 1:CAS:528:DC%2BD3MXhtVSgsL0%3D 11112697
    • (2001) J Cell Sci , vol.114 , pp. 131-139
    • Han, Y.-P.1    Tuan, T.-L.2    Wu, H.3    Hughes, M.4    Garner, W.L.5
  • 17
    • 0028786034 scopus 로고
    • Cytokine and protease levels in healing and non-healing chronic venous leg ulcers
    • 10.1111/j.1600-0625.1995.tb00058.x 1:CAS:528:DyaK28XktVCiuw%3D%3D 8608341
    • IR Harris KC Yee CE Walters WJ Cunliffe JN Kearney EJ Wood, et al. 1995 Cytokine and protease levels in healing and non-healing chronic venous leg ulcers Exp Dermatol 4 342 349 10.1111/j.1600-0625.1995.tb00058.x 1:CAS:528:DyaK28XktVCiuw%3D%3D 8608341
    • (1995) Exp Dermatol , vol.4 , pp. 342-349
    • Harris, I.R.1    Yee, K.C.2    Walters, C.E.3    Cunliffe, W.J.4    Kearney, J.N.5    Wood, E.J.6
  • 18
    • 0030880539 scopus 로고    scopus 로고
    • Up-regulation of elastase in acute wounds of healthy aged humans and chronic venous leg ulcers are associated with matrix degradation
    • 1:STN:280:DyaK2svmtVGluw%3D%3D 9314951
    • S Herrick G Ashcroft G Ireland M Horan C MaCollum M Ferguson 1997 Up-regulation of elastase in acute wounds of healthy aged humans and chronic venous leg ulcers are associated with matrix degradation Lab Invest 77 281 288 1:STN:280:DyaK2svmtVGluw%3D%3D 9314951
    • (1997) Lab Invest , vol.77 , pp. 281-288
    • Herrick, S.1    Ashcroft, G.2    Ireland, G.3    Horan, M.4    MacOllum, C.5    Ferguson, M.6
  • 19
    • 33846627240 scopus 로고    scopus 로고
    • Pathophysiology of acute wound healing
    • DOI 10.1016/j.clindermatol.2006.09.007, PII S0738081X06001386
    • J Lie R Kirsner 2007 Pathophysiology of acute wound healing Clin Dermatol 25 9 18 10.1016/j.clindermatol.2006.09.007 (Pubitemid 46177460)
    • (2007) Clinics in Dermatology , vol.25 , Issue.1 , pp. 9-18
    • Li, J.1    Chen, J.2    Kirsner, R.3
  • 20
    • 0001413484 scopus 로고    scopus 로고
    • Interactions of cytokines, growth factors, and proteases in acute and chronic wounds
    • 10.1046/j.1524-475X.1996.40404.x 1:STN:280:DC%2BD2s7htVeiug%3D%3D
    • BA Mast GS Schultz 1996 Interactions of cytokines, growth factors, and proteases in acute and chronic wounds Wound Rep Reg 4 411 420 10.1046/j.1524-475X.1996.40404.x 1:STN:280:DC%2BD2s7htVeiug%3D%3D
    • (1996) Wound Rep Reg , vol.4 , pp. 411-420
    • Mast, B.A.1    Schultz, G.S.2
  • 21
    • 0027945440 scopus 로고
    • Ulcus cruris: Abheilung unter konservativer Therapie. Eine prospektive Studie
    • W Mayer W Jochmann H Partsch 1994 Ulcus cruris: Abheilung unter konservativer Therapie. Eine prospektive Studie Wien Med Wschr 44 250 252
    • (1994) Wien Med Wschr , vol.44 , pp. 250-252
    • Mayer, W.1    Jochmann, W.2    Partsch, H.3
  • 22
    • 34447634142 scopus 로고    scopus 로고
    • In vitro binding of matrix metalloproteinase-2 (MMP-2), MMP-9, and bacterial collagenase on collagenous wound dressings
    • DOI 10.1111/j.1524-475X.2007.00263.x
    • I Metzmacher P Ruth M Abel W Friess 2007 In vitro binding of matrix metalloproteinases-2 (MMP-2), MMP-13, and bacterial collagenase on collagenous wound dressings Wound Rep Reg 15 549 555 10.1111/j.1524-475X.2007.00263.x (Pubitemid 47087648)
    • (2007) Wound Repair and Regeneration , vol.15 , Issue.4 , pp. 549-555
    • Metzmacher, I.1    Ruth, P.2    Abel, M.3    Friess, W.4
  • 23
    • 0033977260 scopus 로고    scopus 로고
    • Interaction of water-soluble collagen with poly(acrylic acid)
    • DOI 10.1016/S0142-9612(99)00204-5, PII S0142961299002045
    • T Nezu FM Winnik 2000 Interaction of water-soluble collagen with poly(acrylic acid) Biomaterials 21 415 419 10.1016/S0142-9612(99)00204-5 1:CAS:528:DC%2BD3cXot1GjtQ%3D%3D 10656324 (Pubitemid 30035472)
    • (2000) Biomaterials , vol.21 , Issue.4 , pp. 415-419
    • Nezu, T.1    Winnik, F.M.2
  • 24
    • 0033079612 scopus 로고    scopus 로고
    • MMP-8 is the predominant collagenase in healing wounds and nonhealing ulcers
    • DOI 10.1006/jsre.1998.5495
    • BC Nwomeh HX Liang IK Cohen DR Yager 1999 MMP-8 is the predominant collagenase in healing wounds and nonhealing ulcers J Surg Res 81 189 195 10.1006/jsre.1998.5495 1:CAS:528:DyaK1MXpvF2rtw%3D%3D 9927539 (Pubitemid 29397810)
    • (1999) Journal of Surgical Research , vol.81 , Issue.2 , pp. 189-195
    • Nwomeh, B.C.1    Liang, H.-X.2    Cohen, I.K.3    Yager, D.R.4
  • 25
    • 0030111128 scopus 로고    scopus 로고
    • Collagen-based devices for soft tissue repair
    • DOI 10.1002/(SICI)1097-4636(199621)33:1<35::AID-JBM6>3.0.CO;2-N
    • JM Pachence 1996 Collagen-based devices for soft tissue repair Biomed Mater Res 33 35 40 10.1002/(SICI)1097-4636(199621)33:1<35::AID-JBM6>3.0. CO;2-N 1:CAS:528:DyaK28Xhs1Wksb0%3D (Pubitemid 26094605)
    • (1996) Journal of Biomedical Materials Research , vol.33 , Issue.1 , pp. 35-40
    • Pachence, J.M.1
  • 26
    • 0036298978 scopus 로고    scopus 로고
    • Peptide investigations of pairwise interactions in the collagen triple-helix
    • DOI 10.1006/jmbi.2001.5342
    • AV Persikov JA Ramshaw A Kirkpatrick B Brodsky 2002 Peptide investigations of pairwise interactions in the collagen triple-helix J Mol Biol 316 385 394 10.1006/jmbi.2001.5342 1:CAS:528:DC%2BD38Xht1KitbY%3D 11851346 (Pubitemid 34722152)
    • (2002) Journal of Molecular Biology , vol.316 , Issue.2 , pp. 385-394
    • Persikov, A.V.1    Ramshaw, J.A.M.2    Kirkpatrick, A.3    Brodsky, B.4
  • 28
    • 0031784503 scopus 로고    scopus 로고
    • Patterns of matrix metalloproteinases and TIMP expression in chronic ulcers
    • UK Saarialho-Kere 1998 Patterns of matrix metalloproteinases and TIMP expression in chronic ulcers Arch Dermatol Res 290 Suppl 547 554
    • (1998) Arch Dermatol Res , vol.290 , Issue.SUPPL. , pp. 547-554
    • Saarialho-Kere, U.K.1
  • 29
    • 0031901530 scopus 로고    scopus 로고
    • Correlation of inflammatory cytokines with arthroscopic findings in patients with temporomandibular joint internal derangements
    • DOI 10.1016/S0278-2391(98)90446-3
    • NA Sandler MJ Buckley JE Cillo TW Braun 1998 Correlation of inflammatory cytokines with arthroscopic findings in patients with temporomandibular joint internal derangements J Oral Maxillofac Surg 56 534 543 10.1016/S0278-2391(98) 90446-3 1:STN:280:DyaK1c3ltVaitA%3D%3D 9590334 (Pubitemid 28204887)
    • (1998) Journal of Oral and Maxillofacial Surgery , vol.56 , Issue.5 , pp. 534-543
    • Sandler, N.A.1    Buckley, M.J.2    Cillo, J.E.3    Braun, T.W.4
  • 30
    • 22544434358 scopus 로고    scopus 로고
    • Influence of selected wound dressings on PMN elastase in chronic wound fluid and their antioxidative potential in vitro
    • DOI 10.1016/j.biomaterials.2005.04.030, PII S0142961205003066
    • U Schönfelder M Abel C Wiegand D Klemm P Elsner U-C Hipler 2005 Influence of selected wound dressings on PMN elastase in chronic wound fluid and their antioxidative potential in vitro Biomaterials 26 6664 6673 10.1016/j.biomaterials.2005.04.030 15978664 (Pubitemid 41021759)
    • (2005) Biomaterials , vol.26 , Issue.33 , pp. 6664-6673
    • Schonfelder, U.1    Abel, M.2    Wiegand, C.3    Klemm, D.4    Elsner, P.5    Hipler, U.-C.6
  • 31
    • 0031991632 scopus 로고    scopus 로고
    • Proinflammatory cytokines detectable in synovial fluids from patients with temporomandibular disorders
    • 10.1016/S1079-2104(98)90415-2 1:STN:280:DyaK1c7msVWrtA%3D%3D
    • T Takahashi T Kondoh M Fukuda Y Yamazaki T Toyosaki R Suzuki 1998 Proinflammatory cytokines detectable in synovial fluids from patients with temporomandibular disorders Oral Surg Oral Pathol Oral Radiol Endod 85 135 141 10.1016/S1079-2104(98)90415-2 1:STN:280:DyaK1c7msVWrtA%3D%3D
    • (1998) Oral Surg Oral Pathol Oral Radiol Endod , vol.85 , pp. 135-141
    • Takahashi, T.1    Kondoh, T.2    Fukuda, M.3    Yamazaki, Y.4    Toyosaki, T.5    Suzuki, R.6
  • 32
    • 0027504517 scopus 로고
    • Relation between the physicochemical characteristics of collagen and its interactions with chitosan: I
    • DOI 10.1016/0142-9612(93)90135-O
    • MN Taravel A Domard 1993 Relation between the physicochemical characteristics of collagen and its interactions with chitosan: I Biomaterials 14 930 938 10.1016/0142-9612(93)90135-O 1:CAS:528:DyaK2cXhslehtrc%3D 8268385 (Pubitemid 23305989)
    • (1993) Biomaterials , vol.14 , Issue.12 , pp. 930-938
    • Taravel, M.N.1    Domard, A.2
  • 34
    • 0030740249 scopus 로고    scopus 로고
    • Distinct populations of stromal cells express collagenase-3 (MMP-13) and collagenase-1 (MMP-1) in chronic ulcers but not in normally healing wounds
    • 10.1111/1523-1747.ep12276722 1:STN:280:DyaK2szkvV2mug%3D%3D 9204962
    • M Vaalamo L Mattila N Johansson AL Kariniemi ML Karjalainen-Lindsberg VM Kähäri, et al. 1997 Distinct populations of stromal cells express collagenase-3 (MMP-13) and collagenase-1 (MMP-1) in chronic ulcers but not in normally healing wounds J Invest Dermatol 109 96 101 10.1111/1523-1747. ep12276722 1:STN:280:DyaK2szkvV2mug%3D%3D 9204962
    • (1997) J Invest Dermatol , vol.109 , pp. 96-101
    • Vaalamo, M.1    Mattila, L.2    Johansson, N.3    Kariniemi, A.L.4    Karjalainen-Lindsberg, M.L.5    Kähäri, V.M.6
  • 35
    • 0029943232 scopus 로고    scopus 로고
    • Patterns of matrix metalloproteinase and TIMP-1 expression in chronic and normally healing human cutaneous wounds
    • 10.1111/j.1365-2133.1996.tb03607.x 1:CAS:528:DyaK28XkvFSksbg%3D 8776359
    • M Vaalamo M Weckroth P Puolakkainen J Kere P Saarinen J Lauharanta, et al. 1996 Patterns of matrix metalloproteinase and TIMP-1 expression in chronic and normally healing human cutaneous wounds Br J Dermatol 135 52 59 10.1111/j.1365-2133.1996.tb03607.x 1:CAS:528:DyaK28XkvFSksbg%3D 8776359
    • (1996) Br J Dermatol , vol.135 , pp. 52-59
    • Vaalamo, M.1    Weckroth, M.2    Puolakkainen, P.3    Kere, J.4    Saarinen, P.5    Lauharanta, J.6
  • 36
    • 0042809978 scopus 로고    scopus 로고
    • Biomimetic recognition and immunochemical assay of ligand binding to collagen
    • 1:CAS:528:DC%2BD3sXksFeis7Y%3D 12729079
    • J Vaidyanathan K Chinnaswamy TK Vaidyanathan 2003 Biomimetic recognition and immunochemical assay of ligand binding to collagen J Adhes Dent 5 7 17 1:CAS:528:DC%2BD3sXksFeis7Y%3D 12729079
    • (2003) J Adhes Dent , vol.5 , pp. 7-17
    • Vaidyanathan, J.1    Chinnaswamy, K.2    Vaidyanathan, T.K.3
  • 37
    • 0028261035 scopus 로고
    • Electrostatic interactions in collagen-like triple-helical peptides
    • DOI 10.1021/bi00191a023
    • MG Venugopal JAM Ramshaw E Braswell D Zhu B Brodsky 1994 Electrostatic interactions in collagen-like triple-helical peptides Biochemistry 33 7948 7956 10.1021/bi00191a023 1:CAS:528:DyaK2cXksFalsbc%3D 8011657 (Pubitemid 24223814)
    • (1994) Biochemistry , vol.33 , Issue.25 , pp. 7948-7956
    • Venugopal, M.G.1    Ramshaw, J.A.M.2    Braswell, E.3    Zhu, D.4    Brodsky, B.5
  • 38
    • 0030485195 scopus 로고    scopus 로고
    • Comparative in vitro analysis of topical hemostatic agents
    • DOI 10.1006/jsre.1996.0379
    • WR Wagner JM Pachence J Ristich PC Johnson 1996 Comparative in vitro analysis of topical hemostatic agents J Surg Res 66 100 108 10.1006/jsre.1996. 0379 1:CAS:528:DyaK2sXhsVWrsb8%3D 9024819 (Pubitemid 27081878)
    • (1996) Journal of Surgical Research , vol.66 , Issue.2 , pp. 100-108
    • Wagner, W.R.1    Pachence, J.M.2    Ristich, J.3    Johnson, P.C.4
  • 39
    • 0029972104 scopus 로고    scopus 로고
    • Matrix metalloproteinases, gelatinase and collagenase, in chronic leg ulcers
    • 10.1111/1523-1747.ep12340167 1:CAS:528:DyaK28Xjs1Shurc%3D 8618050
    • M Weckroth A Vaheri J Lauharanta T Sorsa YT Konttinen 1996 Matrix metalloproteinases, gelatinase and collagenase, in chronic leg ulcers J Invest Dermatol 106 1119 1124 10.1111/1523-1747.ep12340167 1:CAS:528:DyaK28Xjs1Shurc%3D 8618050
    • (1996) J Invest Dermatol , vol.106 , pp. 1119-1124
    • Weckroth, M.1    Vaheri, A.2    Lauharanta, J.3    Sorsa, T.4    Konttinen, Y.T.5
  • 40
    • 19744374799 scopus 로고    scopus 로고
    • Overview: Acute and chronic wounds
    • DOI 10.1016/j.cnur.2004.09.002, PII S0029646504000982, Wound Care
    • JD Whitney 2005 Overview: acute and chronic wounds Nurs Clin N Am 40 191 205 10.1016/j.cnur.2004.09.002 (Pubitemid 40744980)
    • (2005) Nursing Clinics of North America , vol.40 , Issue.2 , pp. 191-205
    • Whitney, J.D.1
  • 41
    • 67749137769 scopus 로고    scopus 로고
    • Effects of the sterilization method on the performance of collagen type i on chronic wound parameters in vitro
    • 10.1002/jbm.b.31338 1:CAS:528:DC%2BD1MXot12ms78%3D
    • C Wiegand M Abel P Ruth T Wilhelms D Schulze J Norgauer UC Hipler 2009 Effects of the sterilization method on the performance of collagen type I on chronic wound parameters in vitro J Biomed Mater Res Part B: Appl Biomater 90B 710 719 10.1002/jbm.b.31338 1:CAS:528:DC%2BD1MXot12ms78%3D
    • (2009) J Biomed Mater Res Part B: Appl Biomater , vol.90 , pp. 710-719
    • Wiegand, C.1    Abel, M.2    Ruth, P.3    Wilhelms, T.4    Schulze, D.5    Norgauer, J.6    Hipler, U.C.7
  • 42
    • 67651146740 scopus 로고    scopus 로고
    • Comparative in vitro study on cytotoxicity, antimicrobial activity, and binding capacity for pathophysiological factors in chronic wounds of alginate and silver-containing alginate
    • 10.1111/j.1524-475X.2009.00503.x
    • C Wiegand T Heinze UC Hipler 2009 Comparative in vitro study on cytotoxicity, antimicrobial activity, and binding capacity for pathophysiological factors in chronic wounds of alginate and silver-containing alginate Wound Rep Reg 17 511 521 10.1111/j.1524-475X.2009.00503.x
    • (2009) Wound Rep Reg , vol.17 , pp. 511-521
    • Wiegand, C.1    Heinze, T.2    Hipler, U.C.3
  • 43
    • 36949072834 scopus 로고
    • Formation of the scab and the rate of epithelisation of superficial wounds in the skin of the young domestic pig
    • 10.1038/193293a0 1:STN:280:DyaF387pvFGjsA%3D%3D 14007593
    • GD Winter 1962 Formation of the scab and the rate of epithelisation of superficial wounds in the skin of the young domestic pig Nature 193 293 294 10.1038/193293a0 1:STN:280:DyaF387pvFGjsA%3D%3D 14007593
    • (1962) Nature , vol.193 , pp. 293-294
    • Winter, G.D.1
  • 44
    • 0025667165 scopus 로고
    • Fibronectin profiles in normal and chronic wound fluid
    • 1:STN:280:DyaK3M%2FntlyksQ%3D%3D 2255189
    • AB Wysocki F Grinnel 1990 Fibronectin profiles in normal and chronic wound fluid Lab Invest 63 825 831 1:STN:280:DyaK3M%2FntlyksQ%3D%3D 2255189
    • (1990) Lab Invest , vol.63 , pp. 825-831
    • Wysocki, A.B.1    Grinnel, F.2
  • 45
    • 0027202705 scopus 로고
    • Wound fluid from chronic leg ulcers contains elevated levels of metalloproteinases MMP-2 and MMP-9
    • 10.1111/1523-1747.ep12359590 1:CAS:528:DyaK3sXmsVOisLs%3D 8392530
    • AB Wysocki L Staiano-Coico F Grinnell 1993 Wound fluid from chronic leg ulcers contains elevated levels of metalloproteinases MMP-2 and MMP-9 J Invest Dermatol 101 64 68 10.1111/1523-1747.ep12359590 1:CAS:528:DyaK3sXmsVOisLs%3D 8392530
    • (1993) J Invest Dermatol , vol.101 , pp. 64-68
    • Wysocki, A.B.1    Staiano-Coico, L.2    Grinnell, F.3
  • 46
    • 0347725622 scopus 로고    scopus 로고
    • Ability of chronic wound fluids to degrade peptide growth factors is associated with increased levels of elastase activity and diminished levels of proteinase inhibitors
    • 10.1046/j.1524-475X.1997.50108.x
    • DR Yager SM Chen SI Ward OO Olutoye RF Diegelman IK Cohen 1997 Ability of chronic wound fluids to degrade peptide growth factors is associated with increased levels of elastase activity and diminished levels of proteinase inhibitors Wound Rep Reg 5 23 32 10.1046/j.1524-475X.1997.50108.x
    • (1997) Wound Rep Reg , vol.5 , pp. 23-32
    • Yager, D.R.1    Chen, S.M.2    Ward, S.I.3    Olutoye, O.O.4    Diegelman, R.F.5    Cohen, I.K.6
  • 47
    • 0033384598 scopus 로고    scopus 로고
    • The proteolytic environment of chronic wounds
    • DOI 10.1046/j.1524-475X.1999.00433.x
    • DR Yager BC Nwomeh 1999 The proteolytic environment of chronic wounds Wound Rep Reg 7 433 441 10.1046/j.1524-475X.1999.00433.x 1:STN:280: DC%2BD3c%2FpvVyrug%3D%3D (Pubitemid 30027565)
    • (1999) Wound Repair and Regeneration , vol.7 , Issue.6 , pp. 433-441
    • Yager, D.R.1    Nwomeh, B.C.2
  • 48
    • 32244435241 scopus 로고    scopus 로고
    • Relation between severity of injury and the early activation of interleukins in multiple-injured patients
    • DOI 10.1159/000090337
    • Y Yagmur H Ozturk M Unaldi E Gedik 2005 Relation between severity of injury and the early activation of interleukins in multiple-injured patients Eur Surg Res 37 360 364 10.1159/000090337 1:CAS:528:DC%2BD28Xht1CntL4%3D 16465061 (Pubitemid 43213914)
    • (2005) European Surgical Research , vol.37 , Issue.6 , pp. 360-364
    • Yagmur, Y.1    Ozturk, H.2    Unaldi, M.3    Gedik, E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.