Structural determinants of antimicrobial activity in polymers which mimic host defense peptides

Applied Microbiology and Biotechnology

Volumn 87, Issue 5, 2010, Pages 1605-1615

  Palermo, Edmund F ^a   Kuroda, Kenichi ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Antimicrobial; Cell penetrating; Membrane disruption; Peptide mimic; Polymer; Structure activity

Indexed keywords

ANTI-MICROBIAL ACTIVITY; ANTI-MICROBIAL AGENT; ANTIMICROBIAL POLYMERS; CATIONIC CHARGES; CHEMICAL STRUCTURE; DESIGN PRINCIPLES; FUTURE DIRECTIONS; HOST DEFENSE; INFECTIOUS DISEASE; MEDIATED INTERACTION; MEMBRANE DISRUPTION; MODE OF ACTION; PEPTIDE MIMIC; PEPTIDE MIMICS; PHYSIOCHEMICAL PARAMETERS; POLYMER STRUCTURE; STRUCTURAL DETERMINANTS; STRUCTURAL FACTOR; STRUCTURAL FEATURE; STRUCTURAL PARAMETER;

HYDROPHOBICITY; MICROORGANISMS; PEPTIDES;

POLYMERS;

AMMONIA; ANTIBIOTIC AGENT; ANTIMICROBIAL POLYMER; CATION; GUANIDINE; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; ANTIMICROBIAL CATIONIC PEPTIDE; POLYMER;

ANTIMICROBIAL ACTIVITY; CATION; HYDROPHOBICITY; INFECTIOUS DISEASE; MEMBRANE; PEPTIDE; PHYSICOCHEMICAL PROPERTY; POLYMER;

ANTIMICROBIAL ACTIVITY; CELL STRAIN CACO 2; CHEMICAL STRUCTURE; CYTOTOXICITY; DRUG DESIGN; GRAM NEGATIVE BACTERIUM; HEMAGGLUTINATION; HOST RESISTANCE; HUMAN; HYDROPHOBICITY; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR WEIGHT; SHORT SURVEY; STRUCTURE ACTIVITY RELATION; CHEMICAL PHENOMENA; CHEMISTRY; STATIC ELECTRICITY;

ANTI-INFECTIVE AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; HYDROPHOBICITY; POLYMERS; STATIC ELECTRICITY; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS;

EID: 77955549539     PISSN: 01757598     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00253-010-2687-z     Document Type: Short Survey

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