Ferulic acid inhibits nitric oxide-induced apoptosis by enhancing GABA B1 receptor expression in transient focal cerebral ischemia in rats

Acta Pharmacologica Sinica

Volumn 31, Issue 8, 2010, Pages 889-899

  Cheng, Chin Yi ^a   Su, Shan Yu ^a,b   Tang, Nou Ying ^a   Ho, Tin Yun ^a   Lo, Wan Yu ^a   Hsieh, Ching Liang ^a,b  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Bax; ferulic acid; Inducible nitric oxide synthase; Neuronal nitric oxide synthase; Nitric oxide induced apoptosis; p38 mitogen activated protein kinase

Indexed keywords

3 NITROTYROSINE; 4 AMINOBUTYRIC ACID B RECEPTOR; 4 AMINOBUTYRIC ACID B RECEPTOR SUBUNIT 1; CASPASE 3; CYTOCHROME C; DNA NUCLEOTIDYLEXOTRANSFERASE; FERULIC ACID; INDUCIBLE NITRIC OXIDE SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE P38; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; POSTSYNAPTIC DENSITY PROTEIN 95; PROTEIN BAX; SACLOFEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BRAIN PERFUSION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG MECHANISM; ENZYME PHOSPHORYLATION; ENZYME RELEASE; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROPROTECTION; NICK END LABELING; NONHUMAN; OXYGEN TENSION; PROTEIN EXPRESSION; PROTEIN SECRETION; PROTEIN TRANSPORT; RAT; REPERFUSION; TRANSIENT ISCHEMIC ATTACK; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BRAIN ISCHEMIA; COUMARIC ACIDS; DISEASE MODELS, ANIMAL; FREE RADICAL SCAVENGERS; GENE EXPRESSION REGULATION; MALE; NEUROPROTECTIVE AGENTS; NITRIC OXIDE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-B; REPERFUSION INJURY; TYROSINE;

EID: 77955458298     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2010.66     Document Type: Article

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