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Volumn 107, Issue 27, 2010, Pages 12317-12322

NR4A orphan nuclear receptors as mediators of CREB-dependent neuroprotection

Author keywords

Excitotoxicity; Kainic acid; Oxidative stress

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; KAINIC ACID; NUCLEAR RECEPTOR NUR77; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA COACTIVATOR 1ALPHA; ROLIPRAM;

EID: 77955448019     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1007088107     Document Type: Article
Times cited : (134)

References (51)
  • 1
    • 0037101970 scopus 로고    scopus 로고
    • Function and regulation of CREB family transcription factors in the nervous system
    • Lonze BE, Ginty DD (2002) Function and regulation of CREB family transcription factors in the nervous system. Neuron 35:605-623.
    • (2002) Neuron , vol.35 , pp. 605-623
    • Lonze, B.E.1    Ginty, D.D.2
  • 2
    • 33646564720 scopus 로고    scopus 로고
    • CREB activity maintains the survival of cingulate cortical pyramidal neurons in the adult mouse brain
    • Ao H, Ko SW, Zhuo M (2006) CREB activity maintains the survival of cingulate cortical pyramidal neurons in the adult mouse brain. Mol Pain 2:15.
    • (2006) Mol Pain , vol.2 , pp. 15
    • Ao, H.1    Ko, S.W.2    Zhuo, M.3
  • 3
    • 59449090590 scopus 로고    scopus 로고
    • The CREB/CRE transcriptional pathway: Protection against oxidative stress-mediated neuronal cell death
    • Lee B, et al. (2009) The CREB/CRE transcriptional pathway: Protection against oxidative stress-mediated neuronal cell death. J Neurochem 108:1251-1265.
    • (2009) J Neurochem , vol.108 , pp. 1251-1265
    • Lee, B.1
  • 4
    • 0037171782 scopus 로고    scopus 로고
    • Apoptosis, axonal growth defects, and degeneration of peripheral neurons in mice lacking CREB
    • Lonze BE, Riccio A, Cohen S, Ginty DD (2002) Apoptosis, axonal growth defects, and degeneration of peripheral neurons in mice lacking CREB. Neuron 34:371-385.
    • (2002) Neuron , vol.34 , pp. 371-385
    • Lonze, B.E.1    Riccio, A.2    Cohen, S.3    Ginty, D.D.4
  • 5
    • 0036578784 scopus 로고    scopus 로고
    • Disruption of CREB function in brain leads to neurodegeneration
    • Mantamadiotis T, et al. (2002) Disruption of CREB function in brain leads to neurodegeneration. Nat Genet 31:47-54.
    • (2002) Nat Genet , vol.31 , pp. 47-54
    • Mantamadiotis, T.1
  • 6
    • 0030608446 scopus 로고    scopus 로고
    • The role of the cyclic AMP-responsive element binding protein (CREB) in hypoxic-ischemic brain damage and repair
    • Walton M, Sirimanne E, Williams C, Gluckman P, Dragunow M (1996) The role of the cyclic AMP-responsive element binding protein (CREB) in hypoxic-ischemic brain damage and repair. Brain Res Mol Brain Res 43:21-29.
    • (1996) Brain Res Mol Brain Res , vol.43 , pp. 21-29
    • Walton, M.1    Sirimanne, E.2    Williams, C.3    Gluckman, P.4    Dragunow, M.5
  • 7
    • 12844255861 scopus 로고    scopus 로고
    • CREB-mediated Bcl-2 protein expression after ischemic preconditioning
    • Meller R, et al. (2005) CREB-mediated Bcl-2 protein expression after ischemic preconditioning. J Cereb Blood Flow Metab 25:234-246.
    • (2005) J Cereb Blood Flow Metab , vol.25 , pp. 234-246
    • Meller, R.1
  • 8
    • 0037020516 scopus 로고    scopus 로고
    • Relationship between the activation of cyclic AMP responsive element binding protein and ischemic tolerance in the penumbra region of rat cerebral cortex
    • Nakajima T, et al. (2002) Relationship between the activation of cyclic AMP responsive element binding protein and ischemic tolerance in the penumbra region of rat cerebral cortex. Neurosci Lett 331:13-16.
    • (2002) Neurosci Lett , vol.331 , pp. 13-16
    • Nakajima, T.1
  • 9
    • 0037593888 scopus 로고    scopus 로고
    • Redox regulation of cAMP-responsive element-binding protein and induction of manganous superoxide dismutase in nerve growth factor-dependent cell survival
    • Bedogni B, et al. (2003) Redox regulation of cAMP-responsive element-binding protein and induction of manganous superoxide dismutase in nerve growth factor-dependent cell survival. J Biol Chem 278:16510-16519.
    • (2003) J Biol Chem , vol.278 , pp. 16510-16519
    • Bedogni, B.1
  • 10
    • 63349109785 scopus 로고    scopus 로고
    • CCL3L1 prevents gp120-induced neuron death via the CREB cell signaling pathway
    • Chun H, et al. (2009) CCL3L1 prevents gp120-induced neuron death via the CREB cell signaling pathway. Brain Res 1257:75-88.
    • (2009) Brain Res , vol.1257 , pp. 75-88
    • Chun, H.1
  • 11
    • 58549085810 scopus 로고    scopus 로고
    • CREB activation in the rapid, intermediate, and delayed ischemic preconditioning against hypoxic-ischemia in neonatal rat
    • Lin WY, Chang YC, Lee HT, Huang CC (2009) CREB activation in the rapid, intermediate, and delayed ischemic preconditioning against hypoxic-ischemia in neonatal rat. J Neurochem 108:847-859.
    • (2009) J Neurochem , vol.108 , pp. 847-859
    • Lin, W.Y.1    Chang, Y.C.2    Lee, H.T.3    Huang, C.C.4
  • 12
    • 0035575852 scopus 로고    scopus 로고
    • Phosphorylation of cAMP response element-binding protein in hippocampal neurons as a protective response after exposure to glutamate in vitro and ischemia in vivo
    • Mabuchi T, et al. (2001) Phosphorylation of cAMP response element-binding protein in hippocampal neurons as a protective response after exposure to glutamate in vitro and ischemia in vivo. J Neurosci 21:9204-9213.
    • (2001) J Neurosci , vol.21 , pp. 9204-9213
    • Mabuchi, T.1
  • 13
    • 0032055648 scopus 로고    scopus 로고
    • Identification of a signaling pathway involved in calcium regulation of BDNF expression
    • Shieh PB, Hu SC, Bobb K, Timmusk T, Ghosh A (1998) Identification of a signaling pathway involved in calcium regulation of BDNF expression. Neuron 20:727-740.
    • (1998) Neuron , vol.20 , pp. 727-740
    • Shieh, P.B.1    Hu, S.C.2    Bobb, K.3    Timmusk, T.4    Ghosh, A.5
  • 14
    • 33749999530 scopus 로고    scopus 로고
    • Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators
    • St-Pierre J, et al. (2006) Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators. Cell 127:397-408.
    • (2006) Cell , vol.127 , pp. 397-408
    • St-Pierre, J.1
  • 15
    • 0028887868 scopus 로고
    • Focal brain injury induces multiple immediate early genes encoding zinc finger transcription factors
    • Honkaniemi J, Sagar SM, Pyykönen I, Hicks KJ, Sharp FR (1995) Focal brain injury induces multiple immediate early genes encoding zinc finger transcription factors. Brain Res Mol Brain Res 28:157-163.
    • (1995) Brain Res Mol Brain Res , vol.28 , pp. 157-163
    • Honkaniemi, J.1    Sagar, S.M.2    Pyykönen, I.3    Hicks, K.J.4    Sharp, F.R.5
  • 16
    • 0032949438 scopus 로고    scopus 로고
    • Prolonged expression of zinc finger immediate-early gene mRNAs and decreased protein synthesis following kainic acid induced seizures
    • Honkaniemi J, Sharp FR (1999) Prolonged expression of zinc finger immediate-early gene mRNAs and decreased protein synthesis following kainic acid induced seizures. Eur J Neurosci 11:10-17.
    • (1999) Eur J Neurosci , vol.11 , pp. 10-17
    • Honkaniemi, J.1    Sharp, F.R.2
  • 17
    • 0030798024 scopus 로고    scopus 로고
    • Expression of zinc finger immediate early genes in rat brain after permanent middle cerebral artery occlusion
    • Honkaniemi J, States BA, Weinstein PR, Espinoza J, Sharp FR (1997) Expression of zinc finger immediate early genes in rat brain after permanent middle cerebral artery occlusion. J Cereb Blood Flow Metab 17:636-646.
    • (1997) J Cereb Blood Flow Metab , vol.17 , pp. 636-646
    • Honkaniemi, J.1    States, B.A.2    Weinstein, P.R.3    Espinoza, J.4    Sharp, F.R.5
  • 18
    • 33748323186 scopus 로고    scopus 로고
    • Inductin of neuron-derived orphan receptor-1 in the dentate gyrus of the hippocampal formation following transient global ischemia in the rat
    • Kim Y, et al. (2006) Inductin of neuron-derived orphan receptor-1 in the dentate gyrus of the hippocampal formation following transient global ischemia in the rat. Mol Cells 22:8-12.
    • (2006) Mol Cells , vol.22 , pp. 8-12
    • Kim, Y.1
  • 19
    • 0038526314 scopus 로고    scopus 로고
    • Structure and function of Nurr1 identifies a class of ligandindependent nuclear receptors
    • Wang Z, et al. (2003) Structure and function of Nurr1 identifies a class of ligandindependent nuclear receptors. Nature 423:555-560.
    • (2003) Nature , vol.423 , pp. 555-560
    • Wang, Z.1
  • 20
    • 0028946634 scopus 로고
    • A novel pathway for vitamin a signaling mediated by RXR heterodimerization with NGFI-B and NURR1
    • Perlmann T, Jansson L (1995) A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1. Genes Dev 9:769-782.
    • (1995) Genes Dev , vol.9 , pp. 769-782
    • Perlmann, T.1    Jansson, L.2
  • 21
    • 0034672081 scopus 로고    scopus 로고
    • Docosahexaenoic acid, a ligand for the retinoid X receptor in mouse brain
    • de Urquiza AM, et al. (2000) Docosahexaenoic acid, a ligand for the retinoid X receptor in mouse brain. Science 290:2140-2144.
    • (2000) Science , vol.290 , pp. 2140-2144
    • De Urquiza, A.M.1
  • 22
    • 33747196651 scopus 로고    scopus 로고
    • The NR4A subgroup: Immediate early response genes with pleiotropic physiological roles
    • Maxwell MA, Muscat GE (2006) The NR4A subgroup: Immediate early response genes with pleiotropic physiological roles. Nucl Recept Signal 4:e002.
    • (2006) Nucl Recept Signal , vol.4
    • Maxwell, M.A.1    Muscat, G.E.2
  • 23
    • 48749131177 scopus 로고    scopus 로고
    • CREB has a context-dependent role in activity-regulated transcription and maintains neuronal cholesterol homeostasis
    • Lemberger T, Parkitna JR, Chai M, Schütz G, Engblom D (2008) CREB has a context-dependent role in activity-regulated transcription and maintains neuronal cholesterol homeostasis. FASEB J 22:2872-2879.
    • (2008) FASEB J , vol.22 , pp. 2872-2879
    • Lemberger, T.1    Parkitna, J.R.2    Chai, M.3    Schütz, G.4    Engblom, D.5
  • 24
    • 52149102948 scopus 로고    scopus 로고
    • An intrinsic mechanism of corticogenesis from embryonic stem cells
    • Gaspard N, et al. (2008) An intrinsic mechanism of corticogenesis from embryonic stem cells. Nature 455:351-357.
    • (2008) Nature , vol.455 , pp. 351-357
    • Gaspard, N.1
  • 25
    • 34247629557 scopus 로고    scopus 로고
    • The phosphodiesterase inhibitor rolipram promotes survival of newborn hippocampal neurons after ischemia
    • Sasaki T, et al. (2007) The phosphodiesterase inhibitor rolipram promotes survival of newborn hippocampal neurons after ischemia. Stroke 38:1597-1605.
    • (2007) Stroke , vol.38 , pp. 1597-1605
    • Sasaki, T.1
  • 26
    • 33750312225 scopus 로고    scopus 로고
    • CREB and NF-kappaB transcription factors regulate sensitivity to excitotoxic and oxidative stress induced neuronal cell death
    • Zou J, Crews F (2006) CREB and NF-kappaB transcription factors regulate sensitivity to excitotoxic and oxidative stress induced neuronal cell death. Cell Mol Neurobiol 26:385-405.
    • (2006) Cell Mol Neurobiol , vol.26 , pp. 385-405
    • Zou, J.1    Crews, F.2
  • 27
    • 4744359661 scopus 로고    scopus 로고
    • Nor-1 regulates hippocampal axon guidance, pyramidal cell survival, and seizure susceptibility
    • Pönniö T, Conneely OM (2004) nor-1 regulates hippocampal axon guidance, pyramidal cell survival, and seizure susceptibility. Mol Cell Biol 24:9070-9078.
    • (2004) Mol Cell Biol , vol.24 , pp. 9070-9078
    • Pönniö, T.1    Conneely, O.M.2
  • 28
    • 19944378058 scopus 로고    scopus 로고
    • Neuroprotective action of endogenous PACAP in cultured rat cortical neurons
    • Shintani N, et al. (2005) Neuroprotective action of endogenous PACAP in cultured rat cortical neurons. Regul Pept 126:123-128.
    • (2005) Regul Pept , vol.126 , pp. 123-128
    • Shintani, N.1
  • 29
    • 0036459990 scopus 로고    scopus 로고
    • PACAP protects cerebellar granule neurons against oxidative stress-induced apoptosis
    • Vaudry D, et al. (2002) PACAP protects cerebellar granule neurons against oxidative stress-induced apoptosis. Eur J Neurosci 15:1451-1460.
    • (2002) Eur J Neurosci , vol.15 , pp. 1451-1460
    • Vaudry, D.1
  • 30
    • 0037199666 scopus 로고    scopus 로고
    • Adrenomedullin over-expression in the caudate-putamen of the adult rat brain after ischaemiareperfusion injury
    • Encinas JM, Serrano J, Alonso D, Fernández AP, Rodrigo J (2002) Adrenomedullin over-expression in the caudate-putamen of the adult rat brain after ischaemiareperfusion injury. Neurosci Lett 329:197-200.
    • (2002) Neurosci Lett , vol.329 , pp. 197-200
    • Encinas, J.M.1    Serrano, J.2    Alonso, D.3    Fernández, A.P.4    Rodrigo, J.5
  • 31
    • 33846111645 scopus 로고    scopus 로고
    • Phospho-dependent functional modulation of GABA(B) receptors by the metabolic sensor AMP-dependent protein kinase
    • Kuramoto N, et al. (2007) Phospho-dependent functional modulation of GABA(B) receptors by the metabolic sensor AMP-dependent protein kinase. Neuron 53:233-247.
    • (2007) Neuron , vol.53 , pp. 233-247
    • Kuramoto, N.1
  • 32
    • 50849101356 scopus 로고    scopus 로고
    • Translation arrest and ribonomics in post-ischemic bra Layers and layers of players
    • DeGracia DJ, Jamison JT, Szymanski JJ, Lewis MK (2008) Translation arrest and ribonomics in post-ischemic brain: Layers and layers of players. J Neurochem 106:2288-2301.
    • (2008) J Neurochem , vol.106 , pp. 2288-2301
    • DeGracia, D.J.1    Jamison, J.T.2    Szymanski, J.J.3    Lewis, M.K.4
  • 33
    • 0042905738 scopus 로고    scopus 로고
    • Catalase activity is regulated by c-Abl and Arg in the oxidative stress response
    • Cao C, Leng Y, Kufe D (2003) Catalase activity is regulated by c-Abl and Arg in the oxidative stress response. J Biol Chem 278:29667-29675.
    • (2003) J Biol Chem , vol.278 , pp. 29667-29675
    • Cao, C.1    Leng, Y.2    Kufe, D.3
  • 34
    • 34250329446 scopus 로고    scopus 로고
    • Repression of sestrin family genes contributes to oncogenic Ras-induced reactive oxygen species up-regulation and genetic instability
    • Kopnin PB, Agapova LS, Kopnin BP, Chumakov PM (2007) Repression of sestrin family genes contributes to oncogenic Ras-induced reactive oxygen species up-regulation and genetic instability. Cancer Res 67:4671-4678.
    • (2007) Cancer Res , vol.67 , pp. 4671-4678
    • Kopnin, P.B.1    Agapova, L.S.2    Kopnin, B.P.3    Chumakov, P.M.4
  • 35
    • 0032531916 scopus 로고    scopus 로고
    • Overexpression of SOD1 in transgenic rats protects vulnerable neurons against ischemic damage after global cerebral ischemia and reperfusion
    • Chan PH, et al. (1998) Overexpression of SOD1 in transgenic rats protects vulnerable neurons against ischemic damage after global cerebral ischemia and reperfusion. J Neurosci 18:8292-8299.
    • (1998) J Neurosci , vol.18 , pp. 8292-8299
    • Chan, P.H.1
  • 36
    • 0035827569 scopus 로고    scopus 로고
    • Cellular FLICEinhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex
    • Krueger A, Schmitz I, Baumann S, Krammer PH, Kirchhoff S (2001) Cellular FLICEinhibitory protein splice variants inhibit different steps of caspase-8 activation at the CD95 death-inducing signaling complex. J Biol Chem 276:20633-20640.
    • (2001) J Biol Chem , vol.276 , pp. 20633-20640
    • Krueger, A.1    Schmitz, I.2    Baumann, S.3    Krammer, P.H.4    Kirchhoff, S.5
  • 37
    • 0033927181 scopus 로고    scopus 로고
    • Induction of activin a is essential for the neuroprotective action of basic fibroblast growth factor in vivo
    • Tretter YP, et al. (2000) Induction of activin A is essential for the neuroprotective action of basic fibroblast growth factor in vivo. Nat Med 6:812-815.
    • (2000) Nat Med , vol.6 , pp. 812-815
    • Tretter, Y.P.1
  • 38
    • 41749111752 scopus 로고    scopus 로고
    • Estradiol attenuates the focal cerebral ischemic injury through mTOR/p70S6 kinase signaling pathway
    • Koh PO, et al. (2008) Estradiol attenuates the focal cerebral ischemic injury through mTOR/p70S6 kinase signaling pathway. Neurosci Lett 436:62-66.
    • (2008) Neurosci Lett , vol.436 , pp. 62-66
    • Koh, P.O.1
  • 39
    • 34250322226 scopus 로고    scopus 로고
    • Neuroprotective effects of alpha2-adrenergic receptor agonists
    • Weber B, Steinfath M, Scholz J, Bein B (2007) Neuroprotective effects of alpha2-adrenergic receptor agonists. Drug News Perspect 20:149-154.
    • (2007) Drug News Perspect , vol.20 , pp. 149-154
    • Weber, B.1    Steinfath, M.2    Scholz, J.3    Bein, B.4
  • 40
    • 43449106803 scopus 로고    scopus 로고
    • Neuroprotective effects of estrogens: Cross-talk between estrogen and intracellular insulin signalling
    • González C, Díaz F, Alonso A (2008) Neuroprotective effects of estrogens: Cross-talk between estrogen and intracellular insulin signalling. Infect Disord Drug Targets 8:65-67.
    • (2008) Infect Disord Drug Targets , vol.8 , pp. 65-67
    • González, C.1    Díaz, F.2    Alonso, A.3
  • 41
    • 77951073954 scopus 로고    scopus 로고
    • VEGF as a target for neuroprotection
    • Vezzani A (2008) VEGF as a target for neuroprotection. Epilepsy Curr 8:135-137.
    • (2008) Epilepsy Curr , vol.8 , pp. 135-137
    • Vezzani, A.1
  • 42
    • 2942655572 scopus 로고    scopus 로고
    • Nurr1-RXR heterodimers mediate RXR ligand-induced signaling in neuronal cells
    • Wallen-Mackenzie A, et al. (2003) Nurr1-RXR heterodimers mediate RXR ligand-induced signaling in neuronal cells. Genes Dev 17:3036-3047.
    • (2003) Genes Dev , vol.17 , pp. 3036-3047
    • Wallen-Mackenzie, A.1
  • 43
    • 0042591275 scopus 로고    scopus 로고
    • Identification of the antineoplastic agent 6-mercaptopurine as an activator of the orphan nuclear hormone receptor Nurr1
    • Ordentlich P, Yan Y, Zhou S, Heyman RA (2003) Identification of the antineoplastic agent 6-mercaptopurine as an activator of the orphan nuclear hormone receptor Nurr1. J Biol Chem 278:24791-24799.
    • (2003) J Biol Chem , vol.278 , pp. 24791-24799
    • Ordentlich, P.1    Yan, Y.2    Zhou, S.3    Heyman, R.A.4
  • 44
    • 0038810035 scopus 로고    scopus 로고
    • An autoregulatory loop controls peroxisome proliferator-activated receptor gamma coactivator 1alpha expression in muscle
    • Handschin C, Rhee J, Lin J, Tarr PT, Spiegelman BM (2003) An autoregulatory loop controls peroxisome proliferator-activated receptor gamma coactivator 1alpha expression in muscle. Proc Natl Acad Sci USA 100:7111-7116.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 7111-7116
    • Handschin, C.1    Rhee, J.2    Lin, J.3    Tarr, P.T.4    Spiegelman, B.M.5
  • 45
    • 0344010662 scopus 로고    scopus 로고
    • CREB controls hepatic lipid metabolism through nuclear hormone receptor PPAR-gamma
    • Herzig S, et al. (2003) CREB controls hepatic lipid metabolism through nuclear hormone receptor PPAR-gamma. Nature 426:190-193.
    • (2003) Nature , vol.426 , pp. 190-193
    • Herzig, S.1
  • 46
    • 68949132917 scopus 로고    scopus 로고
    • Combinatorial transcription factor regulation of the cyclic AMP-response element on the Pgc-1alpha promoter in white 3T3-L1 and brown HIB-1B preadipocytes
    • Karamitri A, Shore AM, Docherty K, Speakman JR, Lomax MA (2009) Combinatorial transcription factor regulation of the cyclic AMP-response element on the Pgc-1alpha promoter in white 3T3-L1 and brown HIB-1B preadipocytes. J Biol Chem 284:20738-20752.
    • (2009) J Biol Chem , vol.284 , pp. 20738-20752
    • Karamitri, A.1    Shore, A.M.2    Docherty, K.3    Speakman, J.R.4    Lomax, M.A.5
  • 47
    • 33748463364 scopus 로고    scopus 로고
    • NR4A orphan nuclear receptors are transcriptional regulators of hepatic glucose metabolism
    • Pei L, et al. (2006) NR4A orphan nuclear receptors are transcriptional regulators of hepatic glucose metabolism. Nat Med 12:1048-1055.
    • (2006) Nat Med , vol.12 , pp. 1048-1055
    • Pei, L.1
  • 48
    • 0033755914 scopus 로고    scopus 로고
    • Lentivirus vector gene expression during ES cell-derived hematopoietic development in vitro
    • Hamaguchi I, et al. (2000) Lentivirus vector gene expression during ES cell-derived hematopoietic development in vitro. J Virol 74:10778-10784.
    • (2000) J Virol , vol.74 , pp. 10778-10784
    • Hamaguchi, I.1
  • 49
    • 2342595896 scopus 로고    scopus 로고
    • The CREB family: Key regulators of hepatic metabolism
    • Montminy M, Koo SH, Zhang X (2004) The CREB family: Key regulators of hepatic metabolism. Ann Endocrinol (Paris) 65:73-75.
    • (2004) Ann Endocrinol (Paris) , vol.65 , pp. 73-75
    • Montminy, M.1    Koo, S.H.2    Zhang, X.3
  • 50
    • 0346220073 scopus 로고    scopus 로고
    • Defined conditions for neural commitment and differentiation
    • Ying QL, Smith AG (2003) Defined conditions for neural commitment and differentiation. Methods Enzymol 365:327-341.
    • (2003) Methods Enzymol , vol.365 , pp. 327-341
    • Ying, Q.L.1    Smith, A.G.2
  • 51
    • 0021100690 scopus 로고
    • Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
    • Dignam JD, Lebovitz RM, Roeder RG (1983) Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res 11:1475-1489.
    • (1983) Nucleic Acids Res , vol.11 , pp. 1475-1489
    • Dignam, J.D.1    Lebovitz, R.M.2    Roeder, R.G.3


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