Lys184 deletion in troponin I impairs relaxation kinetics and induces hypercontractility in murine cardiac myofibrils

Cardiovascular Research

Volumn 77, Issue 4, 2008, Pages 676-686

  Iorga, Bogdan ^a,b   Blaudeck, Natascha ^a   Solzin, Johannes ^a   Neulen, Axel ^a   Stehle, Ina ^a   Davila, Alfredo J Lopez ^a   Pfitzer, Gabriele ^a   Stehle, Robert ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

^b UNIVERSITY OF BUCHAREST   (Romania)

Author keywords

Ca2+ sensitization; Cross bridge kinetics; Diastolic dysfunction; Hypercontractility; Sarcomere dynamics

Indexed keywords

CALCIUM; DIACETYL OXIME; LYSINE; TROPONIN I;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CHEMOSENSITIVITY; CONFORMATION; CONTROLLED STUDY; DIASTOLE; EXPERIMENTAL PIG; FAMILIAL HYPERTROPHIC CARDIOMYOPATHY; FLUORESCENCE; FORCE; GENE DELETION; GENE MUTATION; GUINEA PIG; HEART CONTRACTION; HEART LEFT VENTRICLE; HEART MUSCLE CONTRACTILITY; HEART MUSCLE RELAXATION; KINETICS; MOLECULAR DYNAMICS; MOUSE; MUSCLE FIBRIL; MUTANT; NONHUMAN; OSCILLATION; PRIORITY JOURNAL; PROTEIN FUNCTION; REGULATORY MECHANISM; SARCOMERE; SYSTOLE; TRANSGENIC MOUSE; UPREGULATION; WILD TYPE;

EID: 39749106653     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvm113     Document Type: Article

References (31)