Proximity relationships between residue 117 of rabbit skeletal troponin-I and residues in troponin-C and actin

Biophysical Journal

Volumn 81, Issue 1, 2001, Pages 321-333

  Li, Zhixing ^a,e   Gergely, John ^a,b,c   Tao, Terence ^a,c,d  

^a BOSTON BIOMEDICAL RESEARCH INSTITUTE   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; TROPONIN; TROPONIN C;

ALPHA HELIX; ANIMAL TISSUE; ARTICLE; COMPLEX FORMATION; CROSS LINKING; CRYSTAL STRUCTURE; ENERGY TRANSFER; NONHUMAN; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RABBIT; RECEPTOR AFFINITY; RESIDUE ANALYSIS; SKELETAL MUSCLE;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0034950021     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(01)75702-5     Document Type: Article

References (70)

1. Förster energy transfer measurements of thiol 1 to thiol 2 distances in myosin subfragment 1
2. The use of singlet-singlet transfer to study macromolecular assemblies
3. 2- and COOH-terminal regions of skeletal muscle troponin I
4. The troponin complex and regulation of muscle contraction
5. Probing the calcium-induced conformational transition of troponin-C with site-directed mutants
6. Structures of the troponin C regulatory domains in the apo and calcium-saturated states
7. Characterization of wild type and mutant chicken gizzard αcalponin expressed in E. coli
8. Regulation of contraction in striated muscle
9. Proteolytic fragments of troponin C: Interactions with the other troponin subunits and biological activity
10. Inhibition of mutant troponin C activity by an intra-domain disulphide bond
11. Molecular mechanism of troponin-C function
12. Reconstitution of Tn activity from three protein components
13. Purification and properties of the components from troponin
14. Structure of the calcium regulatory muscle protein troponin-C at 2.8 Å resolution
15. 2+-induced conformational transition of troponin C
16. Site-directed mutagenesis by overlap extension using the polymerase chain reaction
17. 2+-switch in the calmodulin superfamily
18. Photo-cross-linking of rabbit skeletal troponin I deletion mutants with troponin C and its thiol mutants: The inhibitory region enhances binding of troponin I fragments to troponin C
19. 2+-dependent structural and environmental changes in the troponin-tropomyosin complex and in reconstituted thin filaments
20. Structure of the troponin complex. Implications of photocross-linking of troponin I to troponin C thiol mutants
21. Cross-linking of residue 57 in the regulatory domain of a mutant rabbit skeletal muscle troponin C to the inhibitory region of troponin I
22. NMR studies delineating spatial relationships within the cardiac troponin I-troponin C complex
23. Thin filament proteins and thin filament-linked regulation of vertebrate muscle contraction
24. Cleavage of a specific bond in troponin C by thrombin
25. Cross-linking of rabbit skeletal muscle troponin with the photoactive reagent 4-maleimidobenzophenone: Identification of residues in troponin I that are close to cysteine-98 of troponin C
26. Cross-linking of rabbit skeletal muscle troponin subunits: Labeling of cysteine-98 of troponin C with 4-maleimidobenzophenone and analysis of products formed in the binary complex with troponin I and the ternary complex with troponins I and T
27. 2-terminal regulatory domain of troponin C
28. Binding of cardiac troponin-I147-163 induces a structural opening in human cardiac tropoin-C
29. Residues 48 and 82 at the N-terminal hydrophobic patch of troponin-C photo-cross-link to Met121 of troponin-I
30. Interactions of troponin-I Met121 with the N-terminal hydrophobic pocket of troponin-C
31. 2+ dependence of the distance between Cys48 and Cys133 of troponin I in the ternary troponin complex and reconstituted thin filaments
32. Localization of Cys133 of rabbit skeletal troponin-I with respect to troponin-C by resonance energy transfer
33. Photo-cross-linking of benzophenone-labeled single cysteine troponin I mutants to other thin filament proteins
34. 2- and COOH-terminal domains of troponin T. ATPase activation and binding to troponin I and troponin C
35. Structure and interaction site of the regulatory domain of troponin-C when complexed with the 96-148 region of troponin-I
36. Interaction of the second binding region of troponin I with the regulatory domain of skeletal muscle troponin C as determined by NMR spectroscopy
37. Defining the region of troponin-I that binds to troponin-C
38. 2+-bound complex: A small-angle x-ray and neutron scattering study
39. Mapping the domain of troponin T responsible for the activation of actomyosin ATPase activity: Identification of residues involved in binding to actin
40. The interaction of rabbit skeletal muscle troponin-T fragments with troponin-I
41. Evidence for two-site binding of troponin I inhibitory peptides to the N and C domains of troponin C
42. Interactions of structural C and regulatory N domains of troponin C with repeated sequence motifs in troponin I
43. Troponin T: Genetics, properties and function
44. Troponin I: Inhibitor or facilitator
45. 2+ regulation of muscle contraction
46. 2 terminus of fast skeletal muscle troponin I in its biological activity
47. NMR solution structure of calcium-saturated skeletal muscle troponin C
48. The use of moment index displacement in analyzing fluorescence time-decay data
49. Conformational variation of calcium-bound troponin C
50. The regulation of rabbit skeletal muscle contraction. Biochemical studies of the interaction of the tropomyosintroponin complex with actin and the proteolytic fragments of myosin
51. Identification and mutagenesis of a highly conserved domain in troponin T responsible for troponin I binding: Potential role for coiled coil interaction
52. 2+ on the in situ structures of troponin C and troponin I: A neutron scattering study
53. Fluorescence energy transfer as a spectroscopic ruler
54. Structural details of a calcium-induced molecular switch: X-ray crystallographic analysis of the calcium-saturated N-terminal domain of troponin C at 1.75 Å resolution
55. Molecular structure of troponin C from chicken skeletal muscle at 3 Å resolution
56. The relationship between biological activity and primary structure of troponin I from white skeletal muscle of the rabbit
57. Synthetic studies of the inhibitory region of rabbit skeletal troponin I
58. Nanosecond fluorescence depolarization studies on actin labeled with 1,5-IAEDANS and dansyl chloride
59. Fluorescence lifetime quenching studies on the accessibilities of actin sulfhydryl sites
60. Conformational changes induced in troponin I by interaction with troponin T and actin/tropomyosin
61. Calcium-induced movement of troponin-I relative to actin in skeletal muscle thin filaments
62. 2+ dependence of the distance between Cys-98 of troponin C and Cys-133 of troponin I in the ternary troponin complex: Resonance energy transfer measurements
63. Excitation energy transfer studies of the proximity between tropomyosin and actin in reconstituted skeletal muscle thin filaments
64. The conformation of the C-terminal region of actin: A site-specific photo-cross-linking study using benzophenone-4-maleimide
65. Thin filament-mediated regulation of cardiac contraction
66. 2+-dependent regulation of muscle contraction
67. 2+ sensitivity of the acto-S1-Tm ATPase activity of the thin filament
68. Crystal structure of troponin C in complex with troponin I fragment at 2.3 Å resolution
69. 2+- triggered conformational transition in troponin C
70. 2+-dependent interactions between the C-Helix of troponin-C and troponin-I. Photo-cross-linking and fluorescence studies using a recombinant troponin-C