Functional consequences of the human cardiac troponin I hypertrophic cardiomyopathy mutation R145G in transgenic mice

Journal of Biological Chemistry

Volumn 283, Issue 29, 2008, Pages 20484-20494

  Wen, Yuhui ^a   Pinto, Jose Renato ^a   Gomes, Aldrin V ^b   Xu, Yuanyuan ^a   Wang, Yingcai ^a   Wang, Ying ^a   Potter, James D ^a,c   Kerrick, W Glenn L ^a  

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL CULTURE; CALCIUM; CARDIOVASCULAR SYSTEM; FIBERS; TRANSIENTS;

ACTIVATION STATES; ATPASE ACTIVITIES; AVERAGE FORCES; CARDIAC TROPONIN; DIASTOLIC DYSFUNCTIONS; ENERGY CONSUMPTIONS; ENERGY COSTS; HYPERTROPHIC CARDIOMYOPATHIES; PAPILLARY MUSCLES; SIMULTANEOUS MEASUREMENTS; TRANSGENIC MOUSE; TURNOVER RATES; WILD TYPES;

PLANTS (BOTANY);

2,3 BUTANEDIONE; ADENOSINE TRIPHOSPHATASE; ARGININE; CALCIUM ION; DIACETYL OXIME; GLYCINE; TROPONIN; TROPONIN I; CALCIUM;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CONTROLLED STUDY; DIASTOLIC DYSFUNCTION; ELECTROSTIMULATION; ENERGY CONSUMPTION; ENERGY COST; ENZYME ACTIVATION; ENZYME ACTIVITY; FORCE; GENE MUTATION; HEART MUSCLE RELAXATION; HEART PAPILLARY MUSCLE; HUMAN; HYPERTROPHIC CARDIOMYOPATHY; MOUSE; MUSCLE FORCE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; STRAIN DIFFERENCE; TRANSGENIC MOUSE; TURNOVER TIME; WILD TYPE; ANIMAL; BODY WEIGHT; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MUTATION; ORGAN SIZE; PATHOLOGY;

MUS; MUS MUSCULUS;

ADENOSINE TRIPHOSPHATASES; ANIMALS; ARGININE; BODY WEIGHT; CALCIUM; CARDIOMYOPATHY, HYPERTROPHIC; GENE EXPRESSION REGULATION; HUMANS; MICE; MICE, TRANSGENIC; MUTATION; ORGAN SIZE; TROPONIN I;

EID: 50649125630     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M801661200     Document Type: Article

References (45)

1. World Health Organization/International Society and Federation of Cardiology Task Force (1980) Br. Heart J. 44, 672-673
2. Marian, A. J., and Roberts, R. (1998) J. Cardiovasc. Electrophysiol. 9, 88-99
3. Seidman, J. G., and Seidman, C. (2001) Cell 104, 557-567
4. Fatkin, D., McConnell, B. K., Mudd, J. O., Semsarian, C., Moskowitz, I. G., Schoen, F. J., Giewat, M., Seidman, C. E., and Seidman, J. G. (2000) J. Clin. Invest. 106, 1351-1359
5. Gomes, A. V., and Potter, J. D. (2004) Ann. N. Y. Acad. Sci. 1015, 214-224
6. Solaro, R. J., and Rarick, H. M. (1998) Circ. Res. 83, 471-480
7. Potter, J. D., and Gergely, J. (1974) Biochemistry 13, 2697-2703
8. Kimura, A., Harada, H., Park, J. E., Nishi, H., Satoh, M., Takahashi, M., Hiroi, S., Sasaoka, T., Ohbuchi, N., Nakamura, T., Koyanagi, T., Hwang, T. H., Choo, J. A., Chung, K. S., Hasegawa, A., Nagai, R., Okazaki, O., Nakamura, H., Matsuzaki, M., Sakamoto, T., Toshima, H., Koga, Y., Imaizumi, T., and Sasazuki, T. (1997) Nat. Genet. 16, 379-382
9. Richard, P., Charron, P., Carrier, L., Ledeuil, C., Cheav, T., Pichereau, C., Benaiche, A., Isnard, R., Dubourg, O., Burban, M., Gueffet, J. P., Millaire, A., Desnos, M., Schwartz, K., Hainque, B., and Komajda, M. (2003) Circulation 107, 2227-2232
10. Van Driest, S. L., Ellsworth, E. G., Ommen, S. R., Tajik, A. J., Gersh, B. J., and Ackerman, M. J. (2003) Circulation 108, 445-451
11. Kokado, H., Shimizu, M., Yoshio, H., Ino, H., Okeie, K., Emoto, Y., Matsuyama, T., Yamaguchi, M., Yasuda, T., Fujino, N., Ito, H., and Mabuchi, H. (2000) Circulation 102, 663-669
12. Morner, S., Richard, P., Kazzam, E., Hainque, B., Schwartz, K., and Waldenstrom, A. (2000) J. Mol. Cell Cardiol. 32, 521-525
13. Kruger, M., Zittrich, S., Redwood, C., Blaudeck, N., James, J., Robbins, J., Pfitzer, G., and Stehle, R. (2005) J. Physiol. 564, 347-357
14. Lang, R., Gomes, A. V., Zhao, J., Housmans, P. R., Miller, T., and Potter, J. D. (2002) J. Biol. Chem. 277, 11670-11678
15. Elliott, K., Watkins, H., and Redwood, C. S. (2000) J. Biol. Chem. 275, 22069-22074
16. Takahashi-Yanaga, F., Morimoto, S., Harada, K., Minakami, R., Shiraishi, F., Ohta, M., Lu, Q. W., Sasaguri, T., and Ohtsuki, I. (2001) J. Mol. Cell Cardiol. 33, 2095-2107
17. Burton, D., Abdulrazzak, H., Knott, A., Elliott, K., Redwood, C., Watkins, H., Marston, S., and Ashley, C. (2002) Biochem. J. 362, 443-451
18. Westfall, M. V., Borton, A. R., Albayya, F. P., and Metzger, J. M. (2002) Circ. Res. 91, 525-531
19. Kohler, J., Chen, Y., Brenner, B., Gordon, A. M., Kraft, T., Martyn, D. A., Regnier, M., Rivera, A. J., Wang, C. K., and Chase, P. B. (2003) Physiol. Genomics 14, 117-128
20. Takahashi-Yanaga, F., Morimoto, S., and Ohtsuki, I. (2000) J. Biochem. (Tokyo) 127, 355-357
21. James, J., Zhang, Y., Osinska, H., Sanbe, A., Klevitsky, R., Hewett, T. E., and Robbins, J. (2000) Circ. Res. 87, 805-811
22. Sanbe, A., James, J., Tuzcu, V., Nas, S., Martin, L., Gulick, J., Osinska, H., Sakthivel, S., Klevitsky, R., Ginsburg, K. S., Bers, D. M., Zinman, B., Lakatta, E. G., and Robbins, J. (2005) Circulation 111, 2330-2338
23. Ausubel, F. M., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A., and Struhl, K. (1995) in Current Protocols in Molecular Biology, Vol. 1, chapter 8, John Wiley & Sons, Inc., New York
24. Brinster, R. L., Chen, H. Y., Trumbauer, M. E., Yagle, M. K., and Palmiter, R. D. (1985) Proc. Natl. Acad. Sci. U. S. A. 82, 4438-4442
25. Donaldson, S. K., and Kerrick, W. G. (1975) J. Gen. Physiol. 66, 427-444
26. Allen, K., Xu, Y. Y., and Kerrick, W. G. (2000) J. Appl. Physiol. 88, 180-185
27. Guth, K., and Wojciechowski, R. (1986) Pflügers Arch. Eur. J. Physiol. 407, 552-557
28. Hernandez, O. M., Szczesna-Cordary, D., Knollmann, B. C., Miller, T., Bell, M., Zhao, J., Sirenko, S. G., Diaz, Z., Guzman, G., Xu, Y., Wang, Y., Kerrick, W. G., and Potter, J. D. (2005) J. Biol. Chem. 280, 37183-37194
29. Wang, Y., Xu, Y., Guth, K., and Kerrick, W. G. (1999) J. Muscle Res. Cell Motil. 20, 645-653
30. Ward, C. W., Williams, J. H., and Kerrick, W. G. L. (2004) J. Biol. Chem. 280, 37183-37194
31. Takashi, R., and Putnam, S. (1979) Anal. Biochem. 92, 375-382
32. Kerrick, W. G., and Xu, Y. (2004) J. Muscle Res. Cell Motil. 25, 107-117
33. Ferenczi, M. A., Homsher, E., and Trentham, D. R. (1984) J. Physiol. 352, 575-599
34. Wang, Y., Xu, Y., Kerrick, W. G., Wang, Y., Guzman, G., Diaz-Perez, Z., and Szczesna-Cordary, D. (2006) J. Mol. Biol. 361, 286-299
35. Ng, W. A., Grupp, I. L., Subramaniam, A., and Robbins, J. (1991) Circ. Res. 68, 1742-1750
36. Sinha, A. M., Umeda, P. K., Kavinsky, C. J., Rajamanickam, C., Hsu, H. J., Jakovcic, S., and Rabinowitz, M. (1982) Proc. Natl. Acad. Sci. U. S. A. 79, 5847-5851
37. Krenz, M., and Robbins, J. (2004) J. Am. Coll. Cardiol. 44, 2390-2397
38. Herron, T. J., Vandenboom, R., Fomicheva, E., Mundada, L., Edwards, T., and Metzger, J. M. (2007) Circ. Res. 100, 1182-1190
39. Abergel, E., and Oblak, A. (2006) Arch. Mal. Coeur Vaiss. 99, 969-974
40. Szczesna, D., Zhang, R., Zhao, J., Jones, M., Guzman, G., and Potter, J. D. (2000) J. Biol. Chem. 275, 624-630
41. Harada, K., and Potter, J. D. (2004) J. Biol. Chem. 279, 14488-14495
42. Robinson, J. M., Wang, Y., Kerrick, W. G., Kawai, R., and Cheung, H. C. (2002) J. Mol. Biol. 322, 1065-1088
43. Wang, Y., and Kerrick, W. G. (2002) J. Appl. Physiol. 92, 2409-2418
44. Johnson, J. D., Collins, J. H., Robertson, S. P., and Potter, J. D. (1980) J. Biol. Chem. 255, 9635-9640
45. Kobayashi, T., and Solaro, R. J. (2006) J. Biol. Chem. 281, 13471-13477