메뉴 건너뛰기




Volumn 169, Issue 4, 2010, Pages 1848-1859

Cortical kynurenic acid bi-directionally modulates prefrontal glutamate levels as assessed by microdialysis and rapid electrochemistry

Author keywords

Astrocytes; Microelectrode array; Schizophrenia; 7 nicotinic receptor

Indexed keywords

ALANINE DERIVATIVE; BUNGAROTOXIN RECEPTOR; GALANTAMINE; GLUTAMIC ACID; KYNURENIC ACID; KYNURENINE; S ETHYLSULFONYLBENZOYLALANINE; UNCLASSIFIED DRUG;

EID: 77955421801     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2010.05.052     Document Type: Article
Times cited : (80)

References (78)
  • 1
    • 0033995561 scopus 로고    scopus 로고
    • Nicotinic receptor activation in human cerebral cortical interneurons: a mechanism for the inhibition and disinhibition of neuronal networks
    • Alkondon M., Pereira E.F., Eisenberg H.J., Albuquerque E.X. Nicotinic receptor activation in human cerebral cortical interneurons: a mechanism for the inhibition and disinhibition of neuronal networks. J Neurosci 2000, 20:66-75.
    • (2000) J Neurosci , vol.20 , pp. 66-75
    • Alkondon, M.1    Pereira, E.F.2    Eisenberg, H.J.3    Albuquerque, E.X.4
  • 2
    • 26444477725 scopus 로고    scopus 로고
    • The cognitive neuroscience of schizophrenia
    • Barch D.M. The cognitive neuroscience of schizophrenia. Annu Rev Clin Psychol 2005, 1:321-353.
    • (2005) Annu Rev Clin Psychol , vol.1 , pp. 321-353
    • Barch, D.M.1
  • 3
    • 44749084727 scopus 로고    scopus 로고
    • The cognitive neuroscience of working memory: relevance to CNTRICS and schizophrenia
    • Barch D.M., Smith E. The cognitive neuroscience of working memory: relevance to CNTRICS and schizophrenia. Biol Psychiatry 2008, 64:11-17.
    • (2008) Biol Psychiatry , vol.64 , pp. 11-17
    • Barch, D.M.1    Smith, E.2
  • 5
    • 0035282173 scopus 로고    scopus 로고
    • Self referencing ceramic based multisite microelectrodes for the detection and elimination of interferences from the measurement of l-glutamate and other analytes
    • Burmeister J.J., Gerhardt G.A. Self referencing ceramic based multisite microelectrodes for the detection and elimination of interferences from the measurement of l-glutamate and other analytes. Anal Chem 2001, 73:1037-1042.
    • (2001) Anal Chem , vol.73 , pp. 1037-1042
    • Burmeister, J.J.1    Gerhardt, G.A.2
  • 6
    • 33747459300 scopus 로고    scopus 로고
    • Increased concentration of cerebral kynurenic acid alters stimulus processing and conditioned responding
    • Chess A.C., Bucci D.J. Increased concentration of cerebral kynurenic acid alters stimulus processing and conditioned responding. Behav Brain Res 2006, 170:326-332.
    • (2006) Behav Brain Res , vol.170 , pp. 326-332
    • Chess, A.C.1    Bucci, D.J.2
  • 7
    • 34248335693 scopus 로고    scopus 로고
    • Elevations of endogenous kynurenic acid produce spatial working memory deficits
    • Chess A.C., Simoni M.K., Alling T.E., Bucci D.J. Elevations of endogenous kynurenic acid produce spatial working memory deficits. Schizophr Bull 2007, 33:797-804.
    • (2007) Schizophr Bull , vol.33 , pp. 797-804
    • Chess, A.C.1    Simoni, M.K.2    Alling, T.E.3    Bucci, D.J.4
  • 8
    • 33947683385 scopus 로고    scopus 로고
    • Distributed network actions by nicotine increase the threshold for spike-timing-dependent plasticity in prefrontal cortex
    • Couey J.J., Meredith R.M., Spijker S., Poorthuis R.B., Smit A.B., Brussaard A.B., Mansvelder H.D. Distributed network actions by nicotine increase the threshold for spike-timing-dependent plasticity in prefrontal cortex. Neuron 2007, 54:73-87.
    • (2007) Neuron , vol.54 , pp. 73-87
    • Couey, J.J.1    Meredith, R.M.2    Spijker, S.3    Poorthuis, R.B.4    Smit, A.B.5    Brussaard, A.B.6    Mansvelder, H.D.7
  • 9
    • 33749074397 scopus 로고    scopus 로고
    • Glutamate and schizophrenia: beyond the dopamine hypothesis
    • Coyle J.T. Glutamate and schizophrenia: beyond the dopamine hypothesis. Cell Mol Neurobiol 2006, 26:365-384.
    • (2006) Cell Mol Neurobiol , vol.26 , pp. 365-384
    • Coyle, J.T.1
  • 10
    • 0032448645 scopus 로고    scopus 로고
    • Nitric oxide synthase and the acetylcholine receptor in the prefrontal cortex: metasynaptic organization of the brain
    • Csillik B., Nemcsók J., Boncz I., Knyihár-Csillik E. Nitric oxide synthase and the acetylcholine receptor in the prefrontal cortex: metasynaptic organization of the brain. Neurobiology (Bp) 1998, 6:383-404.
    • (1998) Neurobiology (Bp) , vol.6 , pp. 383-404
    • Csillik, B.1    Nemcsók, J.2    Boncz, I.3    Knyihár-Csillik, E.4
  • 11
    • 33644804953 scopus 로고    scopus 로고
    • Microelectrode array studies of basal and potassium-evoked release of l-glutamate in the anesthetized rat brain
    • Day B.K., Pomerleau F., Burmesiter J., Huettl P., Gerhardt G.A. Microelectrode array studies of basal and potassium-evoked release of l-glutamate in the anesthetized rat brain. J Neurochem 2006, 96:1626-1635.
    • (2006) J Neurochem , vol.96 , pp. 1626-1635
    • Day, B.K.1    Pomerleau, F.2    Burmesiter, J.3    Huettl, P.4    Gerhardt, G.A.5
  • 12
    • 0036932174 scopus 로고    scopus 로고
    • Decreased muscarinic1 receptors in the dorsolateral prefrontal cortex of subjects with schizophrenia
    • Dean B., McLeod M., Keriakous D., McKenzie J., Scarr E. Decreased muscarinic1 receptors in the dorsolateral prefrontal cortex of subjects with schizophrenia. Mol Psychiatry 2002, 7:1083-1091.
    • (2002) Mol Psychiatry , vol.7 , pp. 1083-1091
    • Dean, B.1    McLeod, M.2    Keriakous, D.3    McKenzie, J.4    Scarr, E.5
  • 13
    • 12144255382 scopus 로고    scopus 로고
    • Glutamate-dopamine in vivo interaction in the prefrontal cortex modulates the release of dopamine and acetylcholine in the nucleus accumbens of the awake rat
    • Del Arco A., Mora F. Glutamate-dopamine in vivo interaction in the prefrontal cortex modulates the release of dopamine and acetylcholine in the nucleus accumbens of the awake rat. J Neural Transm 2005, 112:97-109.
    • (2005) J Neural Transm , vol.112 , pp. 97-109
    • Del Arco, A.1    Mora, F.2
  • 14
    • 44649139791 scopus 로고    scopus 로고
    • Prefrontal cortex-nucleus accumbens interaction: in vivo modulation by dopamine and glutamate in the prefrontal cortex
    • Del Arco A., Mora F. Prefrontal cortex-nucleus accumbens interaction: in vivo modulation by dopamine and glutamate in the prefrontal cortex. Pharmacol Biochem Behav 2008, 90:226-235.
    • (2008) Pharmacol Biochem Behav , vol.90 , pp. 226-235
    • Del Arco, A.1    Mora, F.2
  • 15
    • 47949091887 scopus 로고    scopus 로고
    • Presynaptic α7- and β2-containing nicotinic acetylcholine receptors modulate excitatory amino acid release from rat prefrontal cortex nerve terminals via distinct cellular mechanisms
    • Dickinson J.A., Kew J.N., Wonnacott S. Presynaptic α7- and β2-containing nicotinic acetylcholine receptors modulate excitatory amino acid release from rat prefrontal cortex nerve terminals via distinct cellular mechanisms. Mol Pharmacol 2008, 74:348-359.
    • (2008) Mol Pharmacol , vol.74 , pp. 348-359
    • Dickinson, J.A.1    Kew, J.N.2    Wonnacott, S.3
  • 16
    • 67349269521 scopus 로고    scopus 로고
    • Spatial and intracellular relationships between the alpha7 nicotinic acetylcholine receptor and the vesicular acetylcholine transporter in the prefrontal cortex of rat and mouse
    • Duffy A., Zhou P., Milner T.A., Pickel V.M. Spatial and intracellular relationships between the alpha7 nicotinic acetylcholine receptor and the vesicular acetylcholine transporter in the prefrontal cortex of rat and mouse. Neuroscience 2009, 161:1091-1103.
    • (2009) Neuroscience , vol.161 , pp. 1091-1103
    • Duffy, A.1    Zhou, P.2    Milner, T.A.3    Pickel, V.M.4
  • 17
    • 59149090373 scopus 로고    scopus 로고
    • Pharmacological manipulation of kynurenic acid
    • Erhardt S., Olsson S.K., Engberg G. Pharmacological manipulation of kynurenic acid. CNS Drugs 2009, 23:91-101.
    • (2009) CNS Drugs , vol.23 , pp. 91-101
    • Erhardt, S.1    Olsson, S.K.2    Engberg, G.3
  • 20
    • 0026076136 scopus 로고
    • Blood-brain barrier transport of kynurenines: implications for brain synthesis and metabolism
    • Fukui S., Schwarcz R., Rapoport S.I., Takada Y., Smith Q.R. Blood-brain barrier transport of kynurenines: implications for brain synthesis and metabolism. J Neurochem 1991, 56:2007-2017.
    • (1991) J Neurochem , vol.56 , pp. 2007-2017
    • Fukui, S.1    Schwarcz, R.2    Rapoport, S.I.3    Takada, Y.4    Smith, Q.R.5
  • 21
    • 0017883532 scopus 로고
    • Synthesis and metabolism of l-kynurenine in rat brain
    • Gál E.M., Sherman A.D. Synthesis and metabolism of l-kynurenine in rat brain. J Neurochem 1978, 30:607-613.
    • (1978) J Neurochem , vol.30 , pp. 607-613
    • Gál, E.M.1    Sherman, A.D.2
  • 22
    • 13244266996 scopus 로고    scopus 로고
    • Brain levels and acetylcholinesterase inhibition with galantamine and donepezil in rats, mice, and rabbits
    • Geerts H., Guillaumat P.O., Grantham C., Bode W., Anciaux K., Sachak S. Brain levels and acetylcholinesterase inhibition with galantamine and donepezil in rats, mice, and rabbits. Brain Res 2005, 1033:186-193.
    • (2005) Brain Res , vol.1033 , pp. 186-193
    • Geerts, H.1    Guillaumat, P.O.2    Grantham, C.3    Bode, W.4    Anciaux, K.5    Sachak, S.6
  • 23
    • 0032948548 scopus 로고    scopus 로고
    • Nicotinic receptors in the rat prefrontal cortex: increase in glutamate release and facilitation of mediodorsal thalamo-cortical transmission
    • Gioanni Y., Rougeot C., Clarke P.B.S., Lepousé C., Thierry M., Vidal C. Nicotinic receptors in the rat prefrontal cortex: increase in glutamate release and facilitation of mediodorsal thalamo-cortical transmission. Eur J Neurosci 1999, 11:18-30.
    • (1999) Eur J Neurosci , vol.11 , pp. 18-30
    • Gioanni, Y.1    Rougeot, C.2    Clarke, P.B.S.3    Lepousé, C.4    Thierry, M.5    Vidal, C.6
  • 24
    • 0033519564 scopus 로고    scopus 로고
    • Decreased protein level of nicotinic receptor alpha7 subunit in the frontal cortex from schizophrenic brain
    • Guan Z.Z., Zhang X., Blennow K., Nordberg A. Decreased protein level of nicotinic receptor alpha7 subunit in the frontal cortex from schizophrenic brain. Neuroreport 1999, 10:1779-1782.
    • (1999) Neuroreport , vol.10 , pp. 1779-1782
    • Guan, Z.Z.1    Zhang, X.2    Blennow, K.3    Nordberg, A.4
  • 25
    • 34250156019 scopus 로고    scopus 로고
    • Mitochondrial aspartate aminotransferase: a third kynurenate-producing enzyme in the mammalian brain
    • Guidetti P., Amori L., Sapko M.T., Okuno E., Schwarcz R. Mitochondrial aspartate aminotransferase: a third kynurenate-producing enzyme in the mammalian brain. J Neurochem 2007, 102:103-111.
    • (2007) J Neurochem , vol.102 , pp. 103-111
    • Guidetti, P.1    Amori, L.2    Sapko, M.T.3    Okuno, E.4    Schwarcz, R.5
  • 26
    • 33751558659 scopus 로고    scopus 로고
    • Astrocytic localization of kynurenine aminotransferase II in the rat brain visualized by immunocytochemistry
    • Guidetti P., Hoffman G.E., Melendez-Ferro M., Albuquerque E.X., Schwarcz R. Astrocytic localization of kynurenine aminotransferase II in the rat brain visualized by immunocytochemistry. Glia 2007, 55:78-92.
    • (2007) Glia , vol.55 , pp. 78-92
    • Guidetti, P.1    Hoffman, G.E.2    Melendez-Ferro, M.3    Albuquerque, E.X.4    Schwarcz, R.5
  • 27
    • 0035478066 scopus 로고    scopus 로고
    • The brain metabolite kynurenic acid inhibits α7 nicotinic receptor activity and increases non-α7 nicotinic receptor expression: physiopathological implications
    • Hilmas C., Pereira E.F.R., Alkondon M., Rassoulpour A., Schwarcz R., Albuquerque E.X. The brain metabolite kynurenic acid inhibits α7 nicotinic receptor activity and increases non-α7 nicotinic receptor expression: physiopathological implications. J Neurosci 2001, 21:7463-7473.
    • (2001) J Neurosci , vol.21 , pp. 7463-7473
    • Hilmas, C.1    Pereira, E.F.R.2    Alkondon, M.3    Rassoulpour, A.4    Schwarcz, R.5    Albuquerque, E.X.6
  • 28
    • 0034934938 scopus 로고    scopus 로고
    • Cholinergic systems and schizophrenia: primary pathology or epiphenomena?
    • Hyde T.M., Crook J.M. Cholinergic systems and schizophrenia: primary pathology or epiphenomena?. J Chem Neuroanat 2001, 22:53-63.
    • (2001) J Chem Neuroanat , vol.22 , pp. 53-63
    • Hyde, T.M.1    Crook, J.M.2
  • 29
    • 0024564076 scopus 로고
    • A glycine site associated with N-methyl-d-aspartic acid receptors: characterization and identification of a new class of antagonists
    • Kessler M., Terramani T., Lynch G., Baudry M. A glycine site associated with N-methyl-d-aspartic acid receptors: characterization and identification of a new class of antagonists. J Neurochem 1989, 52:1319-1328.
    • (1989) J Neurochem , vol.52 , pp. 1319-1328
    • Kessler, M.1    Terramani, T.2    Lynch, G.3    Baudry, M.4
  • 31
    • 70349880602 scopus 로고    scopus 로고
    • Second-by-second analysis of alpha7 nicotine receptor regulation of glutamate release in the prefrontal cortex of awake rats
    • Konradsson-Geuken A., Gash C.R., Alexander K., Pomerleau F., Huettl P., Gerhardt G.A., Bruno J.P. Second-by-second analysis of alpha7 nicotine receptor regulation of glutamate release in the prefrontal cortex of awake rats. Synapse 2009, 63:1069-1082.
    • (2009) Synapse , vol.63 , pp. 1069-1082
    • Konradsson-Geuken, A.1    Gash, C.R.2    Alexander, K.3    Pomerleau, F.4    Huettl, P.5    Gerhardt, G.A.6    Bruno, J.P.7
  • 33
    • 0142095005 scopus 로고    scopus 로고
    • NMDA receptor antagonist effects, cortical glutamatergic function, and schizophrenia: toward a paradigm shift in medication development
    • Krystal J.H. NMDA receptor antagonist effects, cortical glutamatergic function, and schizophrenia: toward a paradigm shift in medication development. Psychopharmacology 2003, 169:215-233.
    • (2003) Psychopharmacology , vol.169 , pp. 215-233
    • Krystal, J.H.1
  • 34
    • 0037310070 scopus 로고    scopus 로고
    • Nicotine induces glutamate release from thalamocortical terminals in prefrontal cortex
    • Lambe E.K., Picciotto M.R., Aghajanian G.K. Nicotine induces glutamate release from thalamocortical terminals in prefrontal cortex. Neuropsychopharmacology 2003, 28:216-225.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 216-225
    • Lambe, E.K.1    Picciotto, M.R.2    Aghajanian, G.K.3
  • 35
    • 68949184845 scopus 로고    scopus 로고
    • Discrimination learning, reversal, and set-shifting in first-episode schizophrenia: stability over six years and specific associations with medication type and disorganization syndrome
    • Leeson V.C., Robbins T.W., Matheson E., Hutton S.B., Ron M.A., Barnes T.R., Joyce E.M. Discrimination learning, reversal, and set-shifting in first-episode schizophrenia: stability over six years and specific associations with medication type and disorganization syndrome. Biol Psychiatry 2009, 66:586-593.
    • (2009) Biol Psychiatry , vol.66 , pp. 586-593
    • Leeson, V.C.1    Robbins, T.W.2    Matheson, E.3    Hutton, S.B.4    Ron, M.A.5    Barnes, T.R.6    Joyce, E.M.7
  • 36
    • 33749645423 scopus 로고    scopus 로고
    • Cognitive dysfunction in schizophrenia: convergence of gamma-aminobutyric acid and glutamate alterations
    • Lewis D.A., Moghaddam B. Cognitive dysfunction in schizophrenia: convergence of gamma-aminobutyric acid and glutamate alterations. Arch Neurol 2006, 63:1372-1376.
    • (2006) Arch Neurol , vol.63 , pp. 1372-1376
    • Lewis, D.A.1    Moghaddam, B.2
  • 37
    • 75049084941 scopus 로고    scopus 로고
    • Glutamate-dopamine crosstalk in the rat prefrontal cortex is modulated by alpha7 nicotinic receptors and potentiated by PNU-120596
    • Livingstone P.D., Dickinson J.A., Srinivasan J., Kew J.N., Wonnacott S. Glutamate-dopamine crosstalk in the rat prefrontal cortex is modulated by alpha7 nicotinic receptors and potentiated by PNU-120596. J Mol Neurosci 2010, 40:172-176.
    • (2010) J Mol Neurosci , vol.40 , pp. 172-176
    • Livingstone, P.D.1    Dickinson, J.A.2    Srinivasan, J.3    Kew, J.N.4    Wonnacott, S.5
  • 38
    • 34250716453 scopus 로고    scopus 로고
    • Competitive antagonism between the nicotinic allosteric potentiating ligand galantamine and kynurenic acid at α7* nicotinic receptors
    • Lopes C., Pereira E.F.R., Wu H.-Q., Purushottamachar P., Njar V., Schwarcz R., Albuquerque E.X. Competitive antagonism between the nicotinic allosteric potentiating ligand galantamine and kynurenic acid at α7* nicotinic receptors. J Pharmacol Exp Ther 2007, 322:48-58.
    • (2007) J Pharmacol Exp Ther , vol.322 , pp. 48-58
    • Lopes, C.1    Pereira, E.F.R.2    Wu, H.-Q.3    Purushottamachar, P.4    Njar, V.5    Schwarcz, R.6    Albuquerque, E.X.7
  • 39
    • 0036325889 scopus 로고    scopus 로고
    • Direct evidence that release-stimulating alpha7* nicotinic cholinergic receptors are localized on human and rat brain glutamatergic axon terminals
    • Marchi M., Risso F., Viola C., Cavazzani P., Raiteri M. Direct evidence that release-stimulating alpha7* nicotinic cholinergic receptors are localized on human and rat brain glutamatergic axon terminals. J Neurochem 2002, 80:1071-1078.
    • (2002) J Neurochem , vol.80 , pp. 1071-1078
    • Marchi, M.1    Risso, F.2    Viola, C.3    Cavazzani, P.4    Raiteri, M.5
  • 41
    • 75049085096 scopus 로고    scopus 로고
    • Differential regulation of alpha7 nicotinic receptor gene (CHRNA7) expression in schizophrenic smokers
    • Mexal S., Berger R., Logel J., Ross R.G., Freedman R., Leonard S. Differential regulation of alpha7 nicotinic receptor gene (CHRNA7) expression in schizophrenic smokers. J Mol Neurosci 2010, 40:185-195.
    • (2010) J Mol Neurosci , vol.40 , pp. 185-195
    • Mexal, S.1    Berger, R.2    Logel, J.3    Ross, R.G.4    Freedman, R.5    Leonard, S.6
  • 42
    • 1242293696 scopus 로고    scopus 로고
    • Acetylcholine and choline amperometric enzyme sensors characterized in vitro and in vivo
    • Mitchell K.M. Acetylcholine and choline amperometric enzyme sensors characterized in vitro and in vivo. Anal Chem 2004, 76:1098-1106.
    • (2004) Anal Chem , vol.76 , pp. 1098-1106
    • Mitchell, K.M.1
  • 44
    • 43649087570 scopus 로고    scopus 로고
    • Glutamatergic contributions to nicotinic acetylcholine receptor agonist-evoked cholinergic transients in the prefrontal cortex
    • Parikh V., Man K., Decker M.W., Sarter M. Glutamatergic contributions to nicotinic acetylcholine receptor agonist-evoked cholinergic transients in the prefrontal cortex. J Neurosci 2008, 28:3769-3780.
    • (2008) J Neurosci , vol.28 , pp. 3769-3780
    • Parikh, V.1    Man, K.2    Decker, M.W.3    Sarter, M.4
  • 45
    • 34347265169 scopus 로고    scopus 로고
    • Evidence that α7 nicotinic receptor modulates glutamate release from mouse neocortical gliosomes
    • Patti L., Raiteri L., Grilli M., Zappettini S., Bonanno G., Marchi M. Evidence that α7 nicotinic receptor modulates glutamate release from mouse neocortical gliosomes. Neurochem Int 2007, 51:1-7.
    • (2007) Neurochem Int , vol.51 , pp. 1-7
    • Patti, L.1    Raiteri, L.2    Grilli, M.3    Zappettini, S.4    Bonanno, G.5    Marchi, M.6
  • 47
    • 33646765763 scopus 로고    scopus 로고
    • Modulators of the kynurenine pathway of tryptophan metabolism: synthesis and preliminary biological evaluation of S-4-(ethylsulfonyl)benzoylalanine, a potent and selective kynurenine aminotransferase II (KAT II) inhibitor
    • Pellicciari R., Rizzo R.C., Costantino G., Marinozzi M., Amori L., Guidetti P., Wu H.Q., Schwarcz R. Modulators of the kynurenine pathway of tryptophan metabolism: synthesis and preliminary biological evaluation of S-4-(ethylsulfonyl)benzoylalanine, a potent and selective kynurenine aminotransferase II (KAT II) inhibitor. Chem Med Chem 2006, 1:528-531.
    • (2006) Chem Med Chem , vol.1 , pp. 528-531
    • Pellicciari, R.1    Rizzo, R.C.2    Costantino, G.3    Marinozzi, M.4    Amori, L.5    Guidetti, P.6    Wu, H.Q.7    Schwarcz, R.8
  • 48
    • 0019967973 scopus 로고
    • An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid
    • Perkins M.N., Stone T.W. An iontophoretic investigation of the actions of convulsant kynurenines and their interaction with the endogenous excitant quinolinic acid. Brain Res 1982, 247:184-187.
    • (1982) Brain Res , vol.247 , pp. 184-187
    • Perkins, M.N.1    Stone, T.W.2
  • 49
    • 77953617514 scopus 로고    scopus 로고
    • Reduction of endogenous kynurenate formation enhances extracellular glutamate, hippocampal plasticity and cognitive behavior
    • Potter M.C., Elmer G.I., Bergeron R., Albuquerque E.X., Guidetti P., Wu H.-Q., Schwarcz R. Reduction of endogenous kynurenate formation enhances extracellular glutamate, hippocampal plasticity and cognitive behavior. Neuropsychopharmacology 2010, 35:1734-1742.
    • (2010) Neuropsychopharmacology , vol.35 , pp. 1734-1742
    • Potter, M.C.1    Elmer, G.I.2    Bergeron, R.3    Albuquerque, E.X.4    Guidetti, P.5    Wu, H.-Q.6    Schwarcz, R.7
  • 50
    • 1442299425 scopus 로고    scopus 로고
    • Opposite modulatory roles for adenosine A1 and A2A receptors on glutamate and dopamine release in the shell of the nucleus accumbens. Effects of chronic caffeine exposure
    • Quarta D., Ferré S., Solinas M., You Z.B., Hockemeyer J., Popoli P., Goldberg S.R. Opposite modulatory roles for adenosine A1 and A2A receptors on glutamate and dopamine release in the shell of the nucleus accumbens. Effects of chronic caffeine exposure. J Neurochem 2004, 88:1151-1158.
    • (2004) J Neurochem , vol.88 , pp. 1151-1158
    • Quarta, D.1    Ferré, S.2    Solinas, M.3    You, Z.B.4    Hockemeyer, J.5    Popoli, P.6    Goldberg, S.R.7
  • 51
    • 18144402868 scopus 로고    scopus 로고
    • Nanomolar concentrations of kynurenic acid reduce extracellular dopamine levels in the striatum
    • Rassoulpour A., Wu H.Q., Ferré S., Schwarcz R. Nanomolar concentrations of kynurenic acid reduce extracellular dopamine levels in the striatum. J Neurochem 2005, 93:762-765.
    • (2005) J Neurochem , vol.93 , pp. 762-765
    • Rassoulpour, A.1    Wu, H.Q.2    Ferré, S.3    Schwarcz, R.4
  • 53
    • 33645096364 scopus 로고    scopus 로고
    • Behavioural pharmacology: 40+ years of progress, with a focus on glutamate receptors and cognition
    • Robbins T.W., Murphy E.R. Behavioural pharmacology: 40+ years of progress, with a focus on glutamate receptors and cognition. Trends Pharmacol Sci 2006, 27:141-148.
    • (2006) Trends Pharmacol Sci , vol.27 , pp. 141-148
    • Robbins, T.W.1    Murphy, E.R.2
  • 54
    • 21344459009 scopus 로고    scopus 로고
    • Presynaptic α7 and non-α7 nicotinic acetylcholine receptors modulate [3H]D-aspartate release from rat frontal cortex in vitro
    • Rousseau S.J., Jones W.W., Pullar I.A., Wonnacott S. Presynaptic α7 and non-α7 nicotinic acetylcholine receptors modulate [3H]D-aspartate release from rat frontal cortex in vitro. Neuropharmacology 2005, 49:59-72.
    • (2005) Neuropharmacology , vol.49 , pp. 59-72
    • Rousseau, S.J.1    Jones, W.W.2    Pullar, I.A.3    Wonnacott, S.4
  • 55
    • 34447330987 scopus 로고    scopus 로고
    • Chronic second-by-second measures of l-glutamate in the central nervous system of freely moving rats
    • Rutherford E.C., Pomerleau F., Huettl P., Strömberg I., Gerhardt G.A. Chronic second-by-second measures of l-glutamate in the central nervous system of freely moving rats. J Neurochem 2007, 102:712-722.
    • (2007) J Neurochem , vol.102 , pp. 712-722
    • Rutherford, E.C.1    Pomerleau, F.2    Huettl, P.3    Strömberg, I.4    Gerhardt, G.A.5
  • 57
    • 20844438007 scopus 로고    scopus 로고
    • Cortical cholinergic transmission and cortical information processing in schizophrenia
    • Sarter M., Nelson C.L., Bruno J.P. Cortical cholinergic transmission and cortical information processing in schizophrenia. Schizophr Bull 2005, 31:117-138.
    • (2005) Schizophr Bull , vol.31 , pp. 117-138
    • Sarter, M.1    Nelson, C.L.2    Bruno, J.P.3
  • 58
    • 70350446516 scopus 로고    scopus 로고
    • Decreased cortical muscarinic receptors define a subgroup of subjects with schizophrenia
    • Scarr E., Cowie T.F., Kanellakis S., Sundram S., Pantelis C., Dean B. Decreased cortical muscarinic receptors define a subgroup of subjects with schizophrenia. Mol Psychiatry 2009, 14:1017-1023.
    • (2009) Mol Psychiatry , vol.14 , pp. 1017-1023
    • Scarr, E.1    Cowie, T.F.2    Kanellakis, S.3    Sundram, S.4    Pantelis, C.5    Dean, B.6
  • 59
    • 33748751285 scopus 로고    scopus 로고
    • Galantamine improves cognition in schizophrenic patients stabilized on risperidone
    • Schubert M.H., Young K.A., Hicks P.B. Galantamine improves cognition in schizophrenic patients stabilized on risperidone. Biol Psychiatry 2006, 60:530-533.
    • (2006) Biol Psychiatry , vol.60 , pp. 530-533
    • Schubert, M.H.1    Young, K.A.2    Hicks, P.B.3
  • 61
    • 0042887022 scopus 로고    scopus 로고
    • Micromolar brain levels of kynurenic acid are associated with a disruption of auditory sensory gating in the rat
    • Shepard P.D., Joy B., Clerkin L., Schwarcz R. Micromolar brain levels of kynurenic acid are associated with a disruption of auditory sensory gating in the rat. Neuropsychopharmacology 2003, 28:1454-1462.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 1454-1462
    • Shepard, P.D.1    Joy, B.2    Clerkin, L.3    Schwarcz, R.4
  • 62
    • 0025277138 scopus 로고
    • Determination of extracellular kynurenic acid in the striatum of unanesthetized rats: effect of aminooxyacetic acid
    • Speciale C., Wu H.Q., Gramsbergen J.B., Turski W.A., Ungerstedt U., Schwarcz R. Determination of extracellular kynurenic acid in the striatum of unanesthetized rats: effect of aminooxyacetic acid. Neurosci Lett 1990, 116:198-203.
    • (1990) Neurosci Lett , vol.116 , pp. 198-203
    • Speciale, C.1    Wu, H.Q.2    Gramsbergen, J.B.3    Turski, W.A.4    Ungerstedt, U.5    Schwarcz, R.6
  • 63
    • 34250017113 scopus 로고    scopus 로고
    • Kynurenic acid blocks nicotinic synaptic transmission to hippocampal interneurons in young rats
    • Stone T.W. Kynurenic acid blocks nicotinic synaptic transmission to hippocampal interneurons in young rats. Eur J Neurosci 2007, 25:2656-2665.
    • (2007) Eur J Neurosci , vol.25 , pp. 2656-2665
    • Stone, T.W.1
  • 64
    • 0025482465 scopus 로고
    • Cerebral synthesis and release of kynurenic acid: an endogenous antagonist of excitatory amino acid receptors
    • Swartz K.J., During M.J., Freese A., Beal M.F. Cerebral synthesis and release of kynurenic acid: an endogenous antagonist of excitatory amino acid receptors. J Neurosci 1990, 10:2965-2973.
    • (1990) J Neurosci , vol.10 , pp. 2965-2973
    • Swartz, K.J.1    During, M.J.2    Freese, A.3    Beal, M.F.4
  • 65
    • 38449120712 scopus 로고    scopus 로고
    • Dysfunctional and compensatory prefrontal cortical systems, genes, and the pathogenesis of schizophrenia
    • Tan H.Y., Callicott J.H., Weinberger D.R. Dysfunctional and compensatory prefrontal cortical systems, genes, and the pathogenesis of schizophrenia. Cereb Cortex 2007, 17(Suppl 1):171-181.
    • (2007) Cereb Cortex , vol.17 , Issue.SUPPL. 1 , pp. 171-181
    • Tan, H.Y.1    Callicott, J.H.2    Weinberger, D.R.3
  • 66
    • 77949462775 scopus 로고    scopus 로고
    • Cognitive improvement by activation of alpha7 nicotinic acetylcholine receptors: from animal models to human pathophysiology
    • Thomsen M.S., Hansen H.H., Timmerman D.B., Mikkelsen J.D. Cognitive improvement by activation of alpha7 nicotinic acetylcholine receptors: from animal models to human pathophysiology. Curr Pharm Des 2010, 16:323-343.
    • (2010) Curr Pharm Des , vol.16 , pp. 323-343
    • Thomsen, M.S.1    Hansen, H.H.2    Timmerman, D.B.3    Mikkelsen, J.D.4
  • 67
    • 0027239593 scopus 로고
    • Effect of nicotine on levels of extracellular amino acids in regions of the rat brain in vivo
    • Toth E., Vizi E.S., Lajtha A. Effect of nicotine on levels of extracellular amino acids in regions of the rat brain in vivo. Neuropharmacology 1993, 32:827-832.
    • (1993) Neuropharmacology , vol.32 , pp. 827-832
    • Toth, E.1    Vizi, E.S.2    Lajtha, A.3
  • 68
    • 0024536479 scopus 로고
    • Rat brain slices produce and liberate kynurenic acid upon exposure to l-kynurenine
    • Turski W.A., Gramsbergen J.B.P., Traitler H., Schwarcz R. Rat brain slices produce and liberate kynurenic acid upon exposure to l-kynurenine. J Neurochem 1989, 52:1629-1636.
    • (1989) J Neurochem , vol.52 , pp. 1629-1636
    • Turski, W.A.1    Gramsbergen, J.B.P.2    Traitler, H.3    Schwarcz, R.4
  • 70
    • 0023183119 scopus 로고
    • The continuing problem of false positives in repeated measures ANOVA in psychophysiology: a multivariate solution
    • Vasey M.W., Thayer J.F. The continuing problem of false positives in repeated measures ANOVA in psychophysiology: a multivariate solution. Psychophysiology 1987, 24:479-486.
    • (1987) Psychophysiology , vol.24 , pp. 479-486
    • Vasey, M.W.1    Thayer, J.F.2
  • 71
    • 0027338209 scopus 로고
    • Nicotinic and muscarinic modulations of excitatory synaptic transmission in the rat prefrontal cortex in vitro
    • Vidal C., Changeux J.P. Nicotinic and muscarinic modulations of excitatory synaptic transmission in the rat prefrontal cortex in vitro. Neuroscience 1993, 56:23-32.
    • (1993) Neuroscience , vol.56 , pp. 23-32
    • Vidal, C.1    Changeux, J.P.2
  • 72
    • 0036955770 scopus 로고    scopus 로고
    • Impaired prefrontal inhibition in schizophrenia: relevance for cognitive dysfunction
    • Volk D.W., Lewis D.A. Impaired prefrontal inhibition in schizophrenia: relevance for cognitive dysfunction. Physiol Behav 2002, 77:501-505.
    • (2002) Physiol Behav , vol.77 , pp. 501-505
    • Volk, D.W.1    Lewis, D.A.2
  • 73
    • 33646021946 scopus 로고    scopus 로고
    • 2+/calmodulin signaling pathway in rat prefrontal cortex nerve terminals
    • 2+/calmodulin signaling pathway in rat prefrontal cortex nerve terminals. Synapse 2006, 59:491-501.
    • (2006) Synapse , vol.59 , pp. 491-501
    • Wang, H.W.1    Liao, W.N.2    Chang, C.T.3    Wang, S.J.4
  • 74
    • 77749242786 scopus 로고    scopus 로고
    • Cortical kynurenine pathway metabolism: a novel target for cognitive enhancement in schizophrenia
    • Wonodi I., Schwarcz R. Cortical kynurenine pathway metabolism: a novel target for cognitive enhancement in schizophrenia. Schizophr Bull 2010, 36:211-218.
    • (2010) Schizophr Bull , vol.36 , pp. 211-218
    • Wonodi, I.1    Schwarcz, R.2
  • 75
    • 59149092182 scopus 로고    scopus 로고
    • Bidirectional regulation of extracellular dopamine by endogenous kynurenic acid in the rat medial prefrontal cortex
    • Wu H.Q., Pellicciari R., Schwarcz R. Bidirectional regulation of extracellular dopamine by endogenous kynurenic acid in the rat medial prefrontal cortex. Soc Neurosci Abstr 2006, 32:624.3.
    • (2006) Soc Neurosci Abstr , vol.32
    • Wu, H.Q.1    Pellicciari, R.2    Schwarcz, R.3
  • 76
    • 75049085333 scopus 로고    scopus 로고
    • The astrocyte-derived α7 nicotinic receptor antagonist kynurenic acid controls extracellular glutamate levels in the prefrontal cortex
    • Wu H.Q., Pereira E.F.R., Bruno J.P., Pellicciari R., Albuquerque E.X., Schwarcz R. The astrocyte-derived α7 nicotinic receptor antagonist kynurenic acid controls extracellular glutamate levels in the prefrontal cortex. J Mol Neurosci 2010, 40:204-210.
    • (2010) J Mol Neurosci , vol.40 , pp. 204-210
    • Wu, H.Q.1    Pereira, E.F.R.2    Bruno, J.P.3    Pellicciari, R.4    Albuquerque, E.X.5    Schwarcz, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.