Brain levels and acetylcholinesterase inhibition with galantamine and donepezil in rats, mice, and rabbits

Brain Research

Volumn 1033, Issue 2, 2005, Pages 186-193

  Geerts, Hugo ^a   Guillaumat, Pierre Olivier ^b   Grantham, Christopher ^c   Bode, Wilhelmina ^c   Anciaux, Katelijne ^c   Sachak, Sohel ^d  

^a In Silico Biosciences   (United States)

^b CIT   (France)

^c JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^d JANSSEN RESEARCH AND DEVELOPMENT   (United States)

Author keywords

AChE inhibitors; Brain AChE; Pharmacodynamics; Pharmacokinetics; Rodent

Indexed keywords

DONEPEZIL; GALANTAMINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHOLINESTERASE INHIBITION; CONTROLLED STUDY; DOSE CALCULATION; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG CLEARANCE; INHIBITION KINETICS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RABBIT; RAT;

ACETYLCHOLINESTERASE; ANIMALS; BRAIN; CHOLINESTERASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; GALANTAMINE; INDANS; MALE; MICE; MICE, INBRED C57BL; PIPERIDINES; RABBITS; RATS; RATS, SPRAGUE-DAWLEY; SPECIES SPECIFICITY;

EID: 13244266996     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2004.11.042     Document Type: Article

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