Acid hydrolytic method for determination of ginkgo biloba total flavonoids in Rat plasma by HPLC for pharmacokinetic studies

Tsinghua Science and Technology

Volumn 15, Issue 4, 2010, Pages 452-459

  Hu, Jun ^a   Zhao, Yunan ^a   Ma, Chao ^a   Wang, Weiyu ^a   Xing, Dongming ^a   Du, Lijun ^a  

^a TSINGHUA UNIVERSITY   (China)

Author keywords

acid hydrolysis; flavonoids; ginkgo biloba; isorhamnetin; kaempferol; orthogonal test; quercetin

Indexed keywords

ACID HYDROLYSIS; FLAVONOIDS; GINKGO BILOBA; KAEMPFEROL; ORTHOGONAL TEST;

ACIDS; FATTY ACIDS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PHARMACOKINETICS; PHENOLS; ULTRAVIOLET SPECTROSCOPY;

HYDROLYSIS;

EID: 77955405137     PISSN: 10070214     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1007-0214(10)70087-0     Document Type: Article

References (27)

1. K Ndjoko, JL Wolfender, K Hostettmann Determination of trace amounts of ginkgolic acids in Ginkgo biloba L. leaf extracts and phytopharmaceuticals by liquid chromatography-electrospray mass spectrometry J. Chromatogr. B 744 2 2000 249 255
2. XZ Zhu, XY Li, J Liu Recent pharmacological studies on natural products in China Eur. J. Pharmacol. 500 1-3 2004 221 230
3. A Biber Pharmacokinetics of Ginkgo biloba extracts Pharmacopsychiatry 36 2003 S32 S37
4. G Valli, EG Giardina Benefits, adverse effects and drug interactions of herbal therapies with cardiovascular effects J. Am. Coll. Cardiol. 39 7 2002 1083 1095
5. JM Sorensen Herb-drug, food-drug, nutrient-drug, and drug-drug interactions: Mechanisms involved and their medical implications J. Altern Complement Med. 8 3 2002 293 308
6. ML Chavez, MA Jordan, PI Chavez Evidence-based drug-herbal interactions Life Sci. 78 18 2006 2146 2157
7. PR Ortiz de Montellano Structure, mechanism, and inhibition of cytochrome P450 Drug Metab. Dispos. 23 11 1995 1181 1187
8. JW Budzinski, BC Foster, S Vandenhoek An in vitro evaluation of human cytochrome P450 3A4 inhibition by selected commercial herbal extracts and tinctures Phytomedicine 7 4 2000 273 282
9. C Gaudineau, R Beckerman, S Welbourn Inhibition of human P450 enzymes by multiple constituents of the Ginkgo biloba extract Biochem. Biophys. Res. Commun. 318 4 2004 1072 1078
10. YH Kim, DW Jeong, IB Paek Liquid chromatography with tandem mass spectrometry for the simultaneous determination of baicalein, baicalin, oroxylin A and wogonin in rat plasma J. Chromatogr. B 844 2 2006 261 267
11. VA Bhattaram, U Graefe, C Kohlert Pharmacokinetics and bioavailability of herbal medicinal products Phytomedicine. 9 Suppl 3 2002 1 33
12. U Justesen, P Knuthsen, T Leth Quantitative analysis of flavonols, flavones, and flavanones in fruits, vegetables and beverages by high-performance liquid chromatography with photo-diode array and mass spectrometric detection J. Chromatogr. A 799 1-2 1998 101 110
13. VD Bokkenheuser, CH Shackleton, J Winter Hydrolysis of dietary flavonoid glycosides by strains of intestinal Bacteroides from humans Biochem. J. 248 3 1987 953 956
14. LA Griffiths, A Barrow Metabolism of flavonoid compounds in germ-free rats Biochem. J. 130 4 1972 1161 1162
15. D Cova, L De Angelis, F Giavarini Pharmacokinetics and metabolism of oral diosmin in healthy volunteers Int. J. Clin. Pharmacol. Ther. Toxicol. 30 1 1992 29 33
16. C Manach, C Morand, O Texier Quercetin metabolites in plasma of rats fed diets containing rutin or quercetin J. Nutr. 125 7 1995 1911 1922
17. KD Setchell, NM Brown, P Desai Bioavailability of pure isoflavones in healthy humans and analysis of commercial soy isoflavone supplements J. Nutr. 131 Suppl 4 2001 1362S 1375S
18. PC Hollman, JH de Vries, SD van Leeuwen Absorption of dietary quercetin glycosides and quercetin in healthy ileostomy volunteers Am. J. Clin. Nutr. 62 6 1995 1276 1282
19. G Paganga, CA Rice-Evans The identification of flavonoids as glycosides in human plasma Febs. Lett. 401 1 1997 78 82
20. RA Walgren, JT Lin, RK Kinne Cellular uptake of dietary flavonoid quercetin 4′-beta-glucoside by sodium-dependent glucose transporter SGLT1 J. Pharmacol. Exp. Ther 294 3 2000 837 843
21. T Walle Absorption and metabolism of flavonoids Free. Radic. Biol. Med. 36 7 2004 829 837
22. PG Pietta, C Gardana, PL Mauri Identification of flavonoid metabolites after oral-administration to rats of a Ginkgo-biloba extract Journal of Chromatography B-Biomedical Applications 673 1 1995 75 80
23. PG Pietta, C Gardana, PL Mauri Identification of Ginkgo biloba flavonol metabolites after oral administration to humans J. Chromatogr. B 693 1 1997 249 255
24. W Mullen, BA Graf, ST Caldwell Determination of flavonol metabolites in plasma and tissues of rats by HPLC-radiocounting and tandem mass spectrometry following oral ingestion of [2-(14)C]quercetin-4′-glucoside J. Agric. Food. Chem. 50 23 2002 6902 6909
25. TA van Beek Chemical analysis of Ginkgo biloba leaves and extracts J. Chromatogr. A 967 1 2002 21 55
26. A Hasler, O Sticher, B Meier Identification and determination of the flavonoids from Ginkgo biloba by high-performance liquid chromatography J. Chromatogr. 605 1 1992 41 48
27. O Sticher Quality of Ginkgo preparations Planta Med. 59 1 1993 2 11