-
1
-
-
0029871708
-
Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine
-
Muslin AJ, Tanner JW, Allen PM, Shaw AS (1996) Interaction of 14-3-3 with signaling proteins is mediated by the recognition of phosphoserine. Cell 84: 889-897.
-
(1996)
Cell
, vol.84
, pp. 889-897
-
-
Muslin, A.J.1
Tanner, J.W.2
Allen, P.M.3
Shaw, A.S.4
-
2
-
-
58149488988
-
The 14-3-3 proteins: Integrators of diverse signaling cues that impact cell fate and cancer development
-
Morrison DK (2009) The 14-3-3 proteins: integrators of diverse signaling cues that impact cell fate and cancer development. Trends Cell Biol 19: 16-23.
-
(2009)
Trends Cell Biol
, vol.19
, pp. 16-23
-
-
Morrison, D.K.1
-
3
-
-
0028901576
-
Regulation of Raf-1 kinase activity by the 14-3-3 family of proteins
-
Li S, Janosch P, Tanji M, Rosenfeld GC, Waymire JC, et al. (1995) Regulation of Raf-1 kinase activity by the 14-3-3 family of proteins. Embo J 14: 685-696.
-
(1995)
Embo J
, vol.14
, pp. 685-696
-
-
Li, S.1
Janosch, P.2
Tanji, M.3
Rosenfeld, G.C.4
Waymire, J.C.5
-
4
-
-
0035976981
-
The G2/M regulator 14-3-3sigma prevents apoptosis through sequestration of Bax
-
Samuel T, Weber HO, Rauch P, Verdoodt B, Eppel JT, et al. (2001) The G2/M regulator 14-3-3sigma prevents apoptosis through sequestration of Bax. J Biol Chem 276: 45201-45206.
-
(2001)
J Biol Chem
, vol.276
, pp. 45201-45206
-
-
Samuel, T.1
Weber, H.O.2
Rauch, P.3
Verdoodt, B.4
Eppel, J.T.5
-
5
-
-
0034752989
-
Cell cycle roles for two 14-3-3 proteins during Drosophila development
-
Su TT, Parry DH, Donahoe B, Chien CT, O'Farrell PH, et al. (2001) Cell cycle roles for two 14-3-3 proteins during Drosophila development. J Cell Sci 114: 3445-3454.
-
(2001)
J Cell Sci
, vol.114
, pp. 3445-3454
-
-
Su, T.T.1
Parry, D.H.2
Donahoe, B.3
Chien, C.T.4
O'Farrell, P.H.5
-
6
-
-
0030611095
-
Mitotic and G2 checkpoint control: Regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216
-
Peng CY, Graves PR, Thoma RS, Wu Z, Shaw AS, et al. (1997) Mitotic and G2 checkpoint control: regulation of 14-3-3 protein binding by phosphorylation of Cdc25C on serine-216. Science 277: 1501-1505.
-
(1997)
Science
, vol.277
, pp. 1501-1505
-
-
Peng, C.Y.1
Graves, P.R.2
Thoma, R.S.3
Wu, Z.4
Shaw, A.S.5
-
7
-
-
0345059753
-
The 14-3-3 cancer connection
-
Hermeking H (2003) The 14-3-3 cancer connection. Nat Rev Cancer 3: 931-943.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 931-943
-
-
Hermeking, H.1
-
8
-
-
12944275670
-
High frequency of hypermethylation at the 14-3-3 sigma locus leads to gene silencing in breast cancer
-
Ferguson AT, Evron E, Umbricht CB, Pandita TK, Chan TA, et al. (2000) High frequency of hypermethylation at the 14-3-3 sigma locus leads to gene silencing in breast cancer. Proc Natl Acad Sci U S A 97: 6049-6054.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 6049-6054
-
-
Ferguson, A.T.1
Evron, E.2
Umbricht, C.B.3
Pandita, T.K.4
Chan, T.A.5
-
9
-
-
0031310665
-
14-3-3 sigma is a p53-regulated inhibitor of G2/M progression
-
Hermeking H, Lengauer C, Polyak K, He TC, Zhang L, et al. (1997) 14-3-3 sigma is a p53-regulated inhibitor of G2/M progression. Mol Cell 1: 3-11.
-
(1997)
Mol Cell
, vol.1
, pp. 3-11
-
-
Hermeking, H.1
Lengauer, C.2
Polyak, K.3
He, T.C.4
Zhang, L.5
-
10
-
-
69249240289
-
14-3-3zeta Cooperates with ErbB2 to promote ductal carcinoma in situ progression to invasive breast cancer by inducing epithelial-mesenchymal transition
-
Lu J, Guo H, Treekitkarnmongkol W, Li P, Zhang J, et al. (2009) 14-3-3zeta Cooperates with ErbB2 to promote ductal carcinoma in situ progression to invasive breast cancer by inducing epithelial-mesenchymal transition. Cancer Cell 16: 195-207.
-
(2009)
Cancer Cell
, vol.16
, pp. 195-207
-
-
Lu, J.1
Guo, H.2
Treekitkarnmongkol, W.3
Li, P.4
Zhang, J.5
-
11
-
-
34548012353
-
Up-regulation of 14-3-3zeta in lung cancer and its implication as prognostic and therapeutic target
-
Fan T, Li R, Todd NW, Qiu Q, Fang HB, et al. (2007) Up-regulation of 14-3-3zeta in lung cancer and its implication as prognostic and therapeutic target. Cancer Res 67: 7901-7906.
-
(2007)
Cancer Res
, vol.67
, pp. 7901-7906
-
-
Fan, T.1
Li, R.2
Todd, N.W.3
Qiu, Q.4
Fang, H.B.5
-
12
-
-
4544269166
-
Enhanced expression of 14-3-3sigma in pancreatic cancer and its role in cell cycle regulation and apoptosis
-
Guweidhi A, Kleeff J, Giese N, El Fitori J, Ketterer K, et al. (2004) Enhanced expression of 14-3-3sigma in pancreatic cancer and its role in cell cycle regulation and apoptosis. Carcinogenesis 25: 1575-1585.
-
(2004)
Carcinogenesis
, vol.25
, pp. 1575-1585
-
-
Guweidhi, A.1
Kleeff, J.2
Giese, N.3
El, F.J.4
Ketterer, K.5
-
13
-
-
11144256205
-
Isoform-specific expression of 14-3-3 proteins in human lung cancer tissues
-
Qi W, Liu X, Qiao D, Martinez JD (2005) Isoform-specific expression of 14-3-3 proteins in human lung cancer tissues. Int J Cancer 113: 359-363.
-
(2005)
Int J Cancer
, vol.113
, pp. 359-363
-
-
Qi, W.1
Liu, X.2
Qiao, D.3
Martinez, J.D.4
-
14
-
-
39749143163
-
Sirt2 interacts with 14-3-3 beta/gamma and down-regulates the activity of p53
-
Jin YH, Kim YJ, Kim DW, Baek KH, Kang BY, et al. (2008) Sirt2 interacts with 14-3-3 beta/gamma and down-regulates the activity of p53. Biochem Biophys Res Commun 368: 690-695.
-
(2008)
Biochem Biophys Res Commun
, vol.368
, pp. 690-695
-
-
Jin, Y.H.1
Kim, Y.J.2
Kim, D.W.3
Baek, K.H.4
Kang, B.Y.5
-
15
-
-
0022408348
-
Experimental metastatic ability of Hras-transformed NIH3T3 cells
-
Bondy GP, Wilson S, Chambers AF (1985) Experimental metastatic ability of Hras-transformed NIH3T3 cells. Cancer Res 45: 6005-6009.
-
(1985)
Cancer Res
, vol.45
, pp. 6005-6009
-
-
Bondy, G.P.1
Wilson, S.2
Chambers, A.F.3
-
16
-
-
0029101797
-
Human breast carcinoma cells transfected with the gene encoding a c-myc promoter-binding protein (MBP-1) inhibits tumors in nude mice
-
Ray RB, Steele R, Seftor E, Hendrix M (1995) Human breast carcinoma cells transfected with the gene encoding a c-myc promoter-binding protein (MBP-1) inhibits tumors in nude mice. Cancer Res 55: 3747-3751.
-
(1995)
Cancer Res
, vol.55
, pp. 3747-3751
-
-
Ray, R.B.1
Steele, R.2
Seftor, E.3
Hendrix, M.4
-
17
-
-
0029120430
-
Activation of Raf-1 by Ras in intact cells
-
Morrison DK (1995) Activation of Raf-1 by Ras in intact cells. Methods Enzymol 255: 301-310.
-
(1995)
Methods Enzymol
, vol.255
, pp. 301-310
-
-
Morrison, D.K.1
-
18
-
-
17944363504
-
Mutation of somatostatin receptor type 5 in an acromegalic patient resistant to somatostatin analog treatment
-
Ballare E, Persani L, Lania AG, Filopanti M, Giammona E, et al. (2001) Mutation of somatostatin receptor type 5 in an acromegalic patient resistant to somatostatin analog treatment. J Clin Endocrinol Metab 86: 3809-3814.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 3809-3814
-
-
Ballare, E.1
Persani, L.2
Lania, A.G.3
Filopanti, M.4
Giammona, E.5
-
19
-
-
0029830747
-
Phosphatidylinositol 3-kinase-independent signal transduction pathway for platelet-derived growth factor-induced chemotaxis
-
Higaki M, Sakaue H, Ogawa W, Kasuga M, Shimokado K (1996) Phosphatidylinositol 3-kinase-independent signal transduction pathway for platelet-derived growth factor-induced chemotaxis. J Biol Chem 271: 29342-29346.
-
(1996)
J Biol Chem
, vol.271
, pp. 29342-29346
-
-
Higaki, M.1
Sakaue, H.2
Ogawa, W.3
Kasuga, M.4
Shimokado, K.5
-
20
-
-
0033729507
-
Role of the beta isoform of 14-3-3 proteins in cellular proliferation and oncogenic transformation
-
Takihara Y, Matsuda Y, Hara J (2000) Role of the beta isoform of 14-3-3 proteins in cellular proliferation and oncogenic transformation. Carcinogenesis 21: 2073-2077.
-
(2000)
Carcinogenesis
, vol.21
, pp. 2073-2077
-
-
Takihara, Y.1
Matsuda, Y.2
Hara, J.3
-
21
-
-
35148852568
-
Overexpression of 14-3-3gamma causes polyploidization in H322 lung cancer cells
-
Qi W, Liu X, Chen W, Li Q, Martinez JD (2007) Overexpression of 14-3-3gamma causes polyploidization in H322 lung cancer cells. Mol Carcinog 46: 847-856.
-
(2007)
Mol Carcinog
, vol.46
, pp. 847-856
-
-
Qi, W.1
Liu, X.2
Chen, W.3
Li, Q.4
Martinez, J.D.5
-
22
-
-
0024512513
-
Overexpression of normal human p53 in established fibroblasts leads to their tumorigenic conversion
-
Tuck SP, Crawford L (1989) Overexpression of normal human p53 in established fibroblasts leads to their tumorigenic conversion. Oncogene Res 4: 81-96.
-
(1989)
Oncogene Res
, vol.4
, pp. 81-96
-
-
Tuck, S.P.1
Crawford, L.2
-
23
-
-
0027944852
-
Activation of Raf-1 by 14-3-3 proteins
-
Fantl WJ, Muslin AJ, Kikuchi A, Martin JA, MacNicol AM, et al. (1994) Activation of Raf-1 by 14-3-3 proteins. Nature 371: 612-614.
-
(1994)
Nature
, vol.371
, pp. 612-614
-
-
Fantl, W.J.1
Muslin, A.J.2
Kikuchi, A.3
Martin, J.A.4
Macnicol, A.M.5
-
25
-
-
4444315579
-
Transformation potential of Ras isoforms correlates with activation of phosphatidylinositol 3-kinase but not ERK
-
Li W, Zhu T, Guan KL (2004) Transformation potential of Ras isoforms correlates with activation of phosphatidylinositol 3-kinase but not ERK. J Biol Chem 279: 37398-37406.
-
(2004)
J Biol Chem
, vol.279
, pp. 37398-37406
-
-
Li, W.1
Zhu, T.2
Guan, K.L.3
-
26
-
-
0034661839
-
Phosphoinositide 3-kinase forms a complex with platelet membrane glycoprotein Ib-IX-V complex and 14-3-3zeta
-
Munday AD, Berndt MC, Mitchell CA (2000) Phosphoinositide 3-kinase forms a complex with platelet membrane glycoprotein Ib-IX-V complex and 14-3-3zeta. Blood 96: 577-584.
-
(2000)
Blood
, vol.96
, pp. 577-584
-
-
Munday, A.D.1
Berndt, M.C.2
Mitchell, C.A.3
-
27
-
-
33646111903
-
Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning
-
Cai SL, Tee AR, Short JD, Bergeron JM, Kim J, et al. (2006) Activity of TSC2 is inhibited by AKT-mediated phosphorylation and membrane partitioning. J Cell Biol 173: 279-289.
-
(2006)
J Cell Biol
, vol.173
, pp. 279-289
-
-
Cai, S.L.1
Tee, A.R.2
Short, J.D.3
Bergeron, J.M.4
Kim, J.5
-
28
-
-
0036479325
-
14-3-3 proteins: Active cofactors in cellular regulation by serine/threonine phosphorylation
-
Tzivion G, Avruch J (2002) 14-3-3 proteins: active cofactors in cellular regulation by serine/threonine phosphorylation. J Biol Chem 277: 3061-3064.
-
(2002)
J Biol Chem
, vol.277
, pp. 3061-3064
-
-
Tzivion, G.1
Avruch, J.2
-
29
-
-
0028141496
-
Transformation of mammalian cells by constitutively active MAP kinase kinase
-
Mansour SJ, Matten WT, Hermann AS, Candia JM, Rong S, et al. (1994) Transformation of mammalian cells by constitutively active MAP kinase kinase. Science 265: 966-970.
-
(1994)
Science
, vol.265
, pp. 966-970
-
-
Mansour, S.J.1
Matten, W.T.2
Hermann, A.S.3
Candia, J.M.4
Rong, S.5
-
30
-
-
51849128358
-
Class I PI3K in oncogenic cellular transformation
-
Zhao L, Vogt PK (2008) Class I PI3K in oncogenic cellular transformation. Oncogene 27: 5486-5496.
-
(2008)
Oncogene
, vol.27
, pp. 5486-5496
-
-
Zhao, L.1
Vogt, P.K.2
-
31
-
-
0029071689
-
14-3-3 is not essential for Raf-1 function: Identification of Raf-1 proteins that are biologically activated in a 14-3-3- and Ras-independent manner
-
Michaud NR, Fabian JR, Mathes KD, Morrison DK (1995) 14-3-3 is not essential for Raf-1 function: identification of Raf-1 proteins that are biologically activated in a 14-3-3- and Ras-independent manner. Mol Cell Biol 15: 3390-3397.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 3390-3397
-
-
Michaud, N.R.1
Fabian, J.R.2
Mathes, K.D.3
Morrison, D.K.4
-
33
-
-
0037112527
-
14-3-3 interacts with the tumor suppressor tuberin at Akt phosphorylation site(s)
-
Liu MY, Cai S, Espejo A, Bedford MT, Walker CL (2002) 14-3-3 interacts with the tumor suppressor tuberin at Akt phosphorylation site(s). Cancer Res 62: 6475-6480.
-
(2002)
Cancer Res
, vol.62
, pp. 6475-6480
-
-
Liu, M.Y.1
Cai, S.2
Espejo, A.3
Bedford, M.T.4
Walker, C.L.5
-
34
-
-
0347988005
-
Loss of Tsc1/Tsc2 activates mTOR and disrupts PI3K-Akt signaling through downregulation of PDGFR
-
Zhang H, Cicchetti G, Onda H, Koon HB, Asrican K, et al. (2003) Loss of Tsc1/Tsc2 activates mTOR and disrupts PI3K-Akt signaling through downregulation of PDGFR. J Clin Invest 112: 1223-1233.
-
(2003)
J Clin Invest
, vol.112
, pp. 1223-1233
-
-
Zhang, H.1
Cicchetti, G.2
Onda, H.3
Koon, H.B.4
Asrican, K.5
-
35
-
-
17444431201
-
Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis
-
Ma L, Chen Z, Erdjument-Bromage H, Tempst P, Pandolfi PP (2005) Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis. Cell 121: 179-193.
-
(2005)
Cell
, vol.121
, pp. 179-193
-
-
Ma, L.1
Chen, Z.2
Erdjument-Bromage, H.3
Tempst, P.4
Pandolfi, P.P.5
-
36
-
-
18544375193
-
Phosphatidylinositol 3-kinase/Akt pathway regulates tuberous sclerosis tumor suppressor complex by phosphorylation of tuberin
-
Dan HC, Sun M, Yang L, Feldman RI, Sui XM, et al. (2002) Phosphatidylinositol 3-kinase/Akt pathway regulates tuberous sclerosis tumor suppressor complex by phosphorylation of tuberin. J Biol Chem 277: 35364-35370.
-
(2002)
J Biol Chem
, vol.277
, pp. 35364-35370
-
-
Dan, H.C.1
Sun, M.2
Yang, L.3
Feldman, R.I.4
Sui, X.M.5
-
37
-
-
0036713778
-
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
-
Inoki K, Li Y, Zhu T, Wu J, Guan KL (2002) TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nat Cell Biol 4: 648-657.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 648-657
-
-
Inoki, K.1
Li, Y.2
Zhu, T.3
Wu, J.4
Guan, K.L.5
-
38
-
-
0036714127
-
Akt regulates growth by directly phosphorylating Tsc2
-
Potter CJ, Pedraza LG, Xu T (2002) Akt regulates growth by directly phosphorylating Tsc2. Nat Cell Biol 4: 658-665.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 658-665
-
-
Potter, C.J.1
Pedraza, L.G.2
Xu, T.3
-
39
-
-
0034597517
-
Frequent hypermethylation of CpG islands and loss of expression of the 14-3-3 sigma gene in human hepatocellular carcinoma
-
Iwata N, Yamamoto H, Sasaki S, Itoh F, Suzuki H, et al. (2000) Frequent hypermethylation of CpG islands and loss of expression of the 14-3-3 sigma gene in human hepatocellular carcinoma. Oncogene 19: 5298-5302.
-
(2000)
Oncogene
, vol.19
, pp. 5298-5302
-
-
Iwata, N.1
Yamamoto, H.2
Sasaki, S.3
Itoh, F.4
Suzuki, H.5
-
40
-
-
0037142070
-
Efp targets 14-3-3 sigma for proteolysis and promotes breast tumour growth
-
Urano T, Saito T, Tsukui T, Fujita M, Hosoi T, et al. (2002) Efp targets 14-3-3 sigma for proteolysis and promotes breast tumour growth. Nature 417: 871-875.
-
(2002)
Nature
, vol.417
, pp. 871-875
-
-
Urano, T.1
Saito, T.2
Tsukui, T.3
Fujita, M.4
Hosoi, T.5
-
41
-
-
33645532245
-
DNA damageinduced protein 14-3-3 sigma inhibits protein kinase B/Akt activation and suppresses Akt-activated cancer
-
Yang H, Wen YY, Zhao R, Lin YL, Fournier K, et al. (2006) DNA damageinduced protein 14-3-3 sigma inhibits protein kinase B/Akt activation and suppresses Akt-activated cancer. Cancer Res 66: 3096-3105.
-
(2006)
Cancer Res
, vol.66
, pp. 3096-3105
-
-
Yang, H.1
Wen, Y.Y.2
Zhao, R.3
Lin, Y.L.4
Fournier, K.5
|