Cross-reactive carbohydrate determinants strongly affect the results of the basophil activation test in hymenoptera-venom allergy

Clinical and Experimental Allergy

Volumn 40, Issue 9, 2010, Pages 1333-1345

  Mertens, M ^a   Amler, S ^a   Moerschbacher, B M ^a   Brehler, R ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

basophil activation test; biological activity; cross reactive carbohydrate determinants; hymenoptera venom allergy; venom double positivity

Indexed keywords

CARBOHYDRATE; HYMENOPTERA VENOM; IMMUNOGLOBULIN E; INSECT VENOM; UNCLASSIFIED DRUG; YELLOW JACKET VENOM;

ADULT; AGED; ALLERGY; ARTICLE; BASOPHIL; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; CROSS REACTION; FEMALE; HEPATITIS B VIRUS; HUMAN; HYMENOPTERA; INTRACUTANEOUS TEST; MAJOR CLINICAL STUDY; MALE; NONHUMAN; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGED; ALLERGENS; ANTIBODY SPECIFICITY; BASOPHILS; BEE VENOMS; CARBOHYDRATES; CROSS REACTIONS; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; HYPERSENSITIVITY; IMMUNOGLOBULIN E; IMMUNOLOGIC TESTS; MALE; MIDDLE AGED; SENSITIVITY AND SPECIFICITY; WASP VENOMS;

EID: 77955367116     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2010.03535.x     Document Type: Article

References (36)

1. Altmann F. The role of protein glycosylation in allergy. Int Arch Allergy Immunol 2007 142 : 99 115.
2. van Ree R. Carbohydrate epitopes and their relevance for the diagnosis and treatment of allergic diseases. Int Arch Allergy Immunol 2002 129 : 189 197.
3. Aalberse RC, Koshte V, Clemens JG. Immunoglobulin E antibodies that crossreact with vegetable foods, pollen, and hymenoptera venom. J Allergy Clin Immunol 1981 68 : 356 364.
4. Mari A. IgE to cross-reactive carbohydrate determinants: analysis of the distribution and appraisal of the in vivo and in vitro reactivity. Int Arch Allergy Immunol 2002 129 : 286 295.
5. Müller UR, Johansen N, Petersen AB, Fromberg-Nielsen J, Haeberli G. Hymenoptera venom allergy: analysis of double positivity to honey bee and Vespula venom by estimation of IgE antibodies to species-specific major allergens Api m1 and Ves v5. Allergy 2009 64 : 543 548.
6. Mari A, Ooievaar-de Heer P, Scala E et al. Evaluation by double-blind placebo-controlled oral challenge of the clinical relevance of IgE antibodies against plant glycans. Allergy 2008 63 : 891 896.
7. van der Veen MJ, van Ree R, Aalberse RC et al. Poor biologic activity of cross-reactive IgE directed to carbohydrate determinants of glycoproteins. J Allergy Clin Immunol 1997 100 : 327 334.
8. Ebo DG, Hagendorens MM, Bridts CH, De Clerck LS, Stevens WJ. Sensitization to cross-reactive carbohydrate determinants and the ubiquitous protein profilin: mimickers of allergy. Clin Exp Allergy 2004 34 : 137 144.
9. Mari A, Iacovacci P, Afferni C et al. Specific IgE to cross-reactive carbohydrate determinants strongly affect the in vitro diagnosis of allergic diseases. J Allergy Clin Immunol 1999 103 : 1005 1011.
10. Kochuyt A, Van Hoeyveld EM, Stevens EAM. Prevalence and clinical relevance of specific immunoglobulin E to pollen caused by sting-induced specific immunoglobulin E to cross-reacting carbohydrate determinants in hymenoptera venoms. Clin Exp Allergy 2005 35 : 441 447.
11. Bublin M, Radauer C, Wilson IBH et al. Cross-reactive N-glycans of Api g 5, a high molecular weight glycoprotein allergen from celery, are required for immunoglobulin E binding and activation of effector cells from allergic patients. FASEB J 2003 17 : 1697 1699.
12. Fötisch K, Altmann F, Haustein D, Vieths S. Involvement of carbohydrate epitopes in the IgE response of celery-allergic patients. Int Arch Allergy Immunol 1999 120 : 30 42.
13. Foetisch K, Westphal S, Lauer I et al. Biological activity of IgE specific for cross-reactive carbohydrate determinants. J Allergy Clin Immunol 2003 111 : 889 896.
14. Batanero E, Crespo JF, Monsalve RI, Martín-Esteban M, Villalba M, Rodríguez R. IgE-binding and histamine-release capabilities of the main carbohydrate component isolated from the major allergen of olive tree pollen, Ole e 1. J Allergy Clin Immunol 1999 103 : 147 153.
15. Iacovacci P, Afferni C, Butteroni C et al. Comparison between the native glycosylated and the recombinant Cup a1 allergen: role of carbohydrates in the histamine release from basophils. Clin Exp Allergy 2002 32 : 1620 1627.
16. Wicklein D, Lindner B, Moll H et al. Carbohydrate moieties can induce mediator release: a detailed characterization of two major timothy grass pollen allergens. Biol Chem 2004 385 : 397 407.
17. Müller U, Roth A, Yman L, Patrizzi R. Use of RAST technique in wasp sting hypersensitivity. Cross-reactions between various insect antigens are specially considered. Allergy 1978 33 : 197 202.
18. Egner W, Ward C, Brown DL, Ewan PW. The frequency and clinical significance of specific IgE to both wasp (Vespula) and honey-bee (Apis) venoms in the same patient. Clin Exp Allergy 1998 28 : 26 34.
19. Jappe U, Raulf-Heimsoth M, Hoffmann M, Burow G, Hübsch-Müller C, Enk A. In vitro hymenoptera venom allergy diagnosis: improved by screening for cross-reactive carbohydrate determinants and reciprocal inhibition. Allergy 2006 61 : 1220 1229.
20. Ebo DG, Hagendorens MM, Bridts CH, De Clerck LS, Stevens WJ. Hymenoptera venom allergy: taking the sting out of difficult cases. J Investig Allergol Clin Immunol 2007 17 : 357 360.
21. Hemmer W. Cross-reactivity to honeybee and wasp venom. Hautarzt 2008 59 : 194 199.
22. Bonifazi F, Jutel M, Biló BM, Birnbaum J, Muller U. Prevention and treatment of hymenoptera venom allergy: guidelines for clinical practice. Allergy 2005 60 : 1459 1470.
23. Sainte-Laudy J, Sabbah A, Drouet M, Lauret MG, Loiry M. Diagnosis of venom allergy by flow cytometry. Correlation with clinical history, skin tests, specific IgE, histamine and leukotriene C4 release. Clin Exp Allergy 2000 30 : 1166 1171.
24. Binder M, Fierlbeck G, King TI, Valent P, Bühring H. Individual hymenoptera venom compounds induce upregulation of the basophil activation marker ectonucleotide pyrophosphatase/phosphodiesterase 3 (CD203c) in sensitized patients. Int Arch Allergy Immunol 2002 129 : 160 168.
25. Erdmann SM, Sachs B, Kwiecien R, Moll-Slodowy S, Sauer I, Merk HF. The basophil activation test in wasp venom allergy: sensitivity, specificity and monitoring specific immunotherapy. Allergy 2004 59 : 1102 1109.
26. Sturm GJ, Böhm E, Trummer M, Weiglhofer I, Heinemann A, Aberer W. The CD63 basophil activation test in hymenoptera venom allergy: a prospective study. Allergy 2004 59 : 1110 1117.
27. Biló BM, Rueff F, Mosbech H, Bonifazi F, Oude-Elberink JNG. Diagnosis of hymenoptera venom allergy. Allergy 2005 60 : 1339 1349.
28. Eberlein-König B, Varga R, Mempel M, Darsow U, Behrendt H, Ring J. Comparison of basophil activation tests using CD63 or CD203c expression in patients with insect venom allergy. Allergy 2006 61 : 1084 1085.
29. Korosec P, Erzen R, Silar M, Bajrovic N, Kopac P, Kosnik M. Basophil responsiveness in patients with insect sting allergies and negative venom-specific immunoglobulin E and skin prick test results. Clin Exp Allergy 2009 39 : 1730 1737.
30. Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970 227 : 680 685.
31. The European Academy of Allergology and Clinical Immunology. Position paper: allergen standardisation and skin tests. Allergy 1993 48 : 48 82.
32. Kahlert H, Cromwell O, Fiebig H. Measurement of basophil-activating capacity of grass pollen allergens, allergoids and hypoallergenic recombinant derivatives by flow cytometry using anti-CD203c. Clin Exp Allergy 2003 33 : 1266 1272.
33. Wuhrer M, Balog CIA, Koeleman CAM, Deelder AM, Hokke CH. New features of site-specific horseradish peroxidase (HRP) glycosylation uncovered by nano-LC-MS with repeated ion-isolation/fragmentation cycles. Biochem Biophys Acta 2005 1723 : 229 239.
34. Ebo DG, Lechkar B, Schuerwegh AJ, Bridts CH, De Clerck LS, Stevens WJ. Validation of a two-color flow cytometric assay detecting in vitro basophil activation for the diagnosis of IgE-mediated natural rubber latex allergy. Allergy 2002 57 : 706 712.
35. Erdmann SM, Sachs B, Hoffmann-Sommergruber K et al. In vitro allergy diagnosis: should we follow the flow? Clin Exp Allergy 2004 34 : 332 339. Clin Exp Allergy 2004; 34:1498-9; author reply 1499-500.
36. Seismann H, Blank S, Braren I et al. Dissecting cross-reactivity in hymenoptera venom allergy by circumvention of alpha-1,3-core fucosylation. Mol Immunol 2010 47 : 799 808.